ATE343586T1 - Verfahren zur verwendung einer universellen bibliothek von peptid-nukleinsäuren zur optimierung der dns-hybridisierung - Google Patents

Verfahren zur verwendung einer universellen bibliothek von peptid-nukleinsäuren zur optimierung der dns-hybridisierung

Info

Publication number
ATE343586T1
ATE343586T1 AT99933646T AT99933646T ATE343586T1 AT E343586 T1 ATE343586 T1 AT E343586T1 AT 99933646 T AT99933646 T AT 99933646T AT 99933646 T AT99933646 T AT 99933646T AT E343586 T1 ATE343586 T1 AT E343586T1
Authority
AT
Austria
Prior art keywords
library
component
sequence
universal
high throughput
Prior art date
Application number
AT99933646T
Other languages
English (en)
Inventor
Soonkap Hahn
Andrew Patron
Roberto Fagnani
Original Assignee
Biocept Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocept Inc filed Critical Biocept Inc
Application granted granted Critical
Publication of ATE343586T1 publication Critical patent/ATE343586T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003Peptide-nucleic acids (PNAs)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT99933646T 1998-07-09 1999-07-01 Verfahren zur verwendung einer universellen bibliothek von peptid-nukleinsäuren zur optimierung der dns-hybridisierung ATE343586T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11321198A 1998-07-09 1998-07-09

Publications (1)

Publication Number Publication Date
ATE343586T1 true ATE343586T1 (de) 2006-11-15

Family

ID=22348188

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99933646T ATE343586T1 (de) 1998-07-09 1999-07-01 Verfahren zur verwendung einer universellen bibliothek von peptid-nukleinsäuren zur optimierung der dns-hybridisierung

Country Status (8)

Country Link
US (1) US6433134B1 (de)
EP (1) EP1095054B1 (de)
JP (1) JP2002520008A (de)
KR (1) KR100694914B1 (de)
AT (1) ATE343586T1 (de)
AU (1) AU4965499A (de)
DE (1) DE69933770D1 (de)
WO (1) WO2000002899A1 (de)

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US20030175828A1 (en) * 2002-03-15 2003-09-18 Lazar James G. Signal amplification by Hybrid Capture
KR20030084444A (ko) * 2002-04-26 2003-11-01 주식회사 파나진 Pna 올리고머를 합성하기 위한 신규한 단량체 및 그의제조방법
EP1575990B1 (de) * 2002-09-08 2009-11-18 Applera Corporation Festphasengebundene PNA-Dimere und deren Synthese
AU2004247729A1 (en) * 2003-06-12 2004-12-23 Applera Corporation Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same
US7211668B2 (en) 2003-07-28 2007-05-01 Panagene, Inc. PNA monomer and precursor
JP2008527979A (ja) * 2005-01-12 2008-07-31 アプレラ コーポレイション 核酸の選択的増幅のための組成物、方法およびキット
US7482353B2 (en) 2005-06-15 2009-01-27 Applied Biosystems Inc. Compositions and methods pertaining to PNA synthons and oligomers comprising a universal base
WO2007041201A2 (en) 2005-10-03 2007-04-12 Applera Corporation Compositions, methods, and kits for amplifying nucleic acids
US20070172842A1 (en) * 2006-01-25 2007-07-26 Andreas Braun Methods for isolating and identifying novel target-specific structuremers for use in the biological sciences
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US9404864B2 (en) 2013-03-13 2016-08-02 Denovo Sciences, Inc. System for imaging captured cells
US10466160B2 (en) 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
US9174216B2 (en) 2013-03-13 2015-11-03 DeNovo Science, Inc. System for capturing and analyzing cells
US9752181B2 (en) 2013-01-26 2017-09-05 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US9707562B2 (en) 2013-03-13 2017-07-18 Denovo Sciences, Inc. System for capturing and analyzing cells
US9856535B2 (en) 2013-05-31 2018-01-02 Denovo Sciences, Inc. System for isolating cells
US10391490B2 (en) 2013-05-31 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
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KR102626448B1 (ko) 2015-02-24 2024-01-19 더 유니버시티 오브 브리티시 콜롬비아 연속 흐름 미세유체 시스템
ES3047482T3 (en) 2016-01-06 2025-12-03 Univ British Columbia Bifurcating mixers and methods of their use and manufacture
CN106117153B (zh) * 2016-07-05 2018-11-23 淮阴师范学院 2-哌嗪酮的制备方法
WO2018191389A1 (en) * 2017-04-12 2018-10-18 Roche Sequencing Solutions, Inc. A method for sequencing reaction with tagged nucleoside obtained via pictet spengler reaction
WO2019046307A1 (en) 2017-08-29 2019-03-07 Celsee Diagnostics, Inc. SYSTEM AND METHOD FOR ISOLATING AND ANALYZING CELLS
US11419947B2 (en) 2017-10-30 2022-08-23 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
US10633693B1 (en) 2019-04-16 2020-04-28 Celsee Diagnostics, Inc. System and method for leakage control in a particle capture system
US11578322B2 (en) 2019-05-07 2023-02-14 Bio-Rad Laboratories, Inc. System and method for automated single cell processing
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EP3975841A1 (de) 2019-05-30 2022-04-06 Massachusetts Institute of Technology Peptid-nukleinsäurefunktionalisierte hydrogelmikronadeln zur probenahme und detektion von nukleinsäuren in interstitieller flüssigkeit
EP3982716A4 (de) 2019-06-14 2023-09-06 Bio-Rad Laboratories, Inc. System und verfahren für automatisierte einzelzellenverarbeitung und -analyse
CN110511973B (zh) * 2019-07-16 2021-05-07 杭州原合生物科技有限公司 一种用于核酸原位合成的固相载体及其制备方法
KR102403904B1 (ko) * 2019-12-24 2022-06-02 주식회사 시선바이오머티리얼스 용액공정상 pna 올리고머의 제조방법
US11504719B2 (en) 2020-03-12 2022-11-22 Bio-Rad Laboratories, Inc. System and method for receiving and delivering a fluid for sample processing
KR20220057138A (ko) 2020-10-29 2022-05-09 엘지전자 주식회사 청소기
CN118369438A (zh) 2021-12-10 2024-07-19 伯乐实验室有限公司 用形态可调节功能化颗粒进行样品处理的组合物、方法和系统
KR102804687B1 (ko) 2023-02-10 2025-05-12 엘지전자 주식회사 청소기 및 청소기 제어 방법

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Also Published As

Publication number Publication date
JP2002520008A (ja) 2002-07-09
WO2000002899A9 (en) 2000-07-27
US6433134B1 (en) 2002-08-13
EP1095054B1 (de) 2006-10-25
KR20010074672A (ko) 2001-08-08
DE69933770D1 (de) 2006-12-07
EP1095054A1 (de) 2001-05-02
AU4965499A (en) 2000-02-01
KR100694914B1 (ko) 2007-03-14
WO2000002899A1 (en) 2000-01-20

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