ATE34390T1 - Pyrrolyl-amino-piperidine, ein verfahren zu ihrer herstellung und ihre verwendung als medikament. - Google Patents

Pyrrolyl-amino-piperidine, ein verfahren zu ihrer herstellung und ihre verwendung als medikament.

Info

Publication number: ATE34390T1
Authority: AT; Austria
Prior art keywords: hydrogen; piperidines; pyrrolyl; medication; amino
Prior art date: 1983-09-19

Application number

AT84110975T

Other languages

English (en)

Inventor

Richard Charles Effland

Joseph Thomas Klein

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-19

Filing date

1984-09-14

Publication date

1988-06-15

1984-09-14 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1988-06-15 Application granted granted Critical

1988-06-15 Publication of ATE34390T1 publication Critical patent/ATE34390T1/de

Links

229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
150000002431 hydrogen Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
FIVYWRFRMCVAEE-UHFFFAOYSA-N n-(1h-pyrrol-2-yl)piperidin-1-amine Chemical class C1CCCCN1NC1=CC=CN1 FIVYWRFRMCVAEE-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT84110975T 1983-09-19 1984-09-14 Pyrrolyl-amino-piperidine, ein verfahren zu ihrer herstellung und ihre verwendung als medikament. ATE34390T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/533,677 US4452803A (en)	1983-09-19	1983-09-19	Pyrrolylaminopiperidines
EP84110975A EP0141968B1 (de)	1983-09-19	1984-09-14	Pyrrolyl-amino-piperidine, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament

Publications (1)

Publication Number	Publication Date
ATE34390T1 true ATE34390T1 (de)	1988-06-15

Family

ID=24126985

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT84110975T ATE34390T1 (de)	1983-09-19	1984-09-14	Pyrrolyl-amino-piperidine, ein verfahren zu ihrer herstellung und ihre verwendung als medikament.

Country Status (14)

Country	Link
US (1)	US4452803A (de)
EP (1)	EP0141968B1 (de)
JP (1)	JPS6087285A (de)
KR (1)	KR880002626B1 (de)
AT (1)	ATE34390T1 (de)
AU (1)	AU577313B2 (de)
CA (1)	CA1262547A (de)
DE (1)	DE3471307D1 (de)
DK (1)	DK443784A (de)
ES (4)	ES8607296A1 (de)
GR (1)	GR80385B (de)
HU (2)	HU193903B (de)
PT (1)	PT79219B (de)
ZA (1)	ZA847328B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4546105A (en) *	1984-09-04	1985-10-08	Hoechst-Roussel Pharmaceuticals Inc.	Pyrrolylaminopiperidines, compositions thereof and methods of use
US6140349A (en) *	1998-02-02	2000-10-31	Merck & Co., Inc.	Cyclic amine modulators of chemokine receptor activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4172835A (en) *	1973-06-21	1979-10-30	Sterling Drug Inc.	1-(Phenylamino)pyrrole
GB1476503A (en) *	1973-06-21	1977-06-16	Sterling Drug Inc	1-arylamino-and 1-arylimino-pyrroles and preparation thereof
CH583195A5 (en) *	1974-03-21	1976-12-31	Siegfried Ag	Schiff's bases prodn. from 1-amino 3-phenylindole - by reaction with aldehydes, useful as bacteriostats and fungistats
US4348524A (en) *	1980-03-28	1982-09-07	Ciba-Geigy Corporation	Amide derivatives of polyalkylpiperidines
US4302455A (en) *	1980-04-14	1981-11-24	Merck & Co., Inc.	2-(4-Aminopiperidino)pyrazines

1983
- 1983-09-19 US US06/533,677 patent/US4452803A/en not_active Expired - Fee Related
1984
- 1984-09-13 HU HU843460A patent/HU193903B/hu not_active IP Right Cessation
- 1984-09-13 HU HU873061A patent/HU199140B/hu not_active IP Right Cessation
- 1984-09-14 AT AT84110975T patent/ATE34390T1/de not_active IP Right Cessation
- 1984-09-14 EP EP84110975A patent/EP0141968B1/de not_active Expired
- 1984-09-14 DE DE8484110975T patent/DE3471307D1/de not_active Expired
- 1984-09-17 ES ES535973A patent/ES8607296A1/es not_active Expired
- 1984-09-17 GR GR80385A patent/GR80385B/el unknown
- 1984-09-18 JP JP59194084A patent/JPS6087285A/ja active Pending
- 1984-09-18 CA CA000463494A patent/CA1262547A/en not_active Expired
- 1984-09-18 DK DK443784A patent/DK443784A/da not_active Application Discontinuation
- 1984-09-18 ZA ZA847328A patent/ZA847328B/xx unknown
- 1984-09-18 PT PT79219A patent/PT79219B/pt unknown
- 1984-09-18 AU AU33259/84A patent/AU577313B2/en not_active Ceased
- 1984-09-19 KR KR1019840005716A patent/KR880002626B1/ko not_active Expired
1985
- 1985-12-16 ES ES549954A patent/ES8701755A1/es not_active Expired
- 1985-12-16 ES ES549953A patent/ES8701754A1/es not_active Expired
- 1985-12-16 ES ES549952A patent/ES8701753A1/es not_active Expired

Also Published As

Publication number	Publication date
DK443784A (da)	1985-03-20
EP0141968B1 (de)	1988-05-18
ES549954A0 (es)	1986-12-01
AU577313B2 (en)	1988-09-22
ES549953A0 (es)	1986-12-01
DE3471307D1 (en)	1988-06-23
AU3325984A (en)	1985-03-28
CA1262547A (en)	1989-10-31
HU199140B (en)	1990-01-29
ES535973A0 (es)	1986-05-16
GR80385B (en)	1985-01-18
ES549952A0 (es)	1986-12-01
ES8607296A1 (es)	1986-05-16
KR850002266A (ko)	1985-05-10
HUT35668A (en)	1985-07-29
JPS6087285A (ja)	1985-05-16
EP0141968A1 (de)	1985-05-22
ES8701754A1 (es)	1986-12-01
US4452803A (en)	1984-06-05
PT79219B (en)	1986-09-10
DK443784D0 (da)	1984-09-18
PT79219A (en)	1984-10-01
KR880002626B1 (ko)	1988-12-07
ES8701753A1 (es)	1986-12-01
HU193903B (en)	1987-12-28
ZA847328B (en)	1985-05-29
ES8701755A1 (es)	1986-12-01

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Legal Events

Date	Code	Title	Description
1988-09-15	UEP	Publication of translation of european patent specification
1991-06-15	REN	Ceased due to non-payment of the annual fee