ATE344031T1 - Thrombopoietin-mimetika - Google Patents
Thrombopoietin-mimetikaInfo
- Publication number
- ATE344031T1 ATE344031T1 AT00984123T AT00984123T ATE344031T1 AT E344031 T1 ATE344031 T1 AT E344031T1 AT 00984123 T AT00984123 T AT 00984123T AT 00984123 T AT00984123 T AT 00984123T AT E344031 T1 ATE344031 T1 AT E344031T1
- Authority
- AT
- Austria
- Prior art keywords
- mammal
- invented
- thrombopoietin mimetics
- mimetics
- thrombopoietin
- Prior art date
Links
- 102000036693 Thrombopoietin Human genes 0.000 title 1
- 108010041111 Thrombopoietin Proteins 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- USYCQABRSUEURP-UHFFFAOYSA-N 1h-benzo[f]benzimidazole Chemical class C1=CC=C2C=C(NC=N3)C3=CC2=C1 USYCQABRSUEURP-UHFFFAOYSA-N 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 206010043554 thrombocytopenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16913099P | 1999-12-06 | 1999-12-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE344031T1 true ATE344031T1 (de) | 2006-11-15 |
Family
ID=22614367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00984123T ATE344031T1 (de) | 1999-12-06 | 2000-12-06 | Thrombopoietin-mimetika |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1244446B1 (de) |
| JP (1) | JP2003515560A (de) |
| AT (1) | ATE344031T1 (de) |
| AU (1) | AU2079901A (de) |
| DE (1) | DE60031714T2 (de) |
| ES (1) | ES2275567T3 (de) |
| WO (1) | WO2001039773A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1552828A4 (de) | 2002-08-14 | 2007-01-24 | Nissan Chemical Ind Ltd | Thrombopoetin-rezeptor-aktivator und verfahren zu seiner herstellung |
| TWI324593B (en) | 2002-10-09 | 2010-05-11 | Nissan Chemical Ind Ltd | Pyrazolone compounds and thrombopoietin receptor activator |
| AU2003302238A1 (en) | 2002-12-03 | 2004-06-23 | Axys Pharmaceuticals, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
| AU2003297925A1 (en) * | 2002-12-13 | 2004-07-09 | Smithkline Beecham Corporation | Thrombopoietin mimetics |
| US8030336B2 (en) * | 2002-12-13 | 2011-10-04 | Ym Biosciences Australia Pty Ltd | Nicotinamide-based kinase inhibitors |
| TW200418791A (en) * | 2003-01-23 | 2004-10-01 | Bristol Myers Squibb Co | Pharmaceutical compositions for inhibiting proteasome |
| CA2535665A1 (en) * | 2003-08-14 | 2005-02-24 | Asahi Kasei Pharma Corporation | Substituted arylalkanoic acid derivative and use thereof |
| US8729117B2 (en) | 2004-06-02 | 2014-05-20 | Pharmacyclics, Inc. | Factor VIIa inhibitor |
| CA2588979C (en) | 2004-12-08 | 2013-01-22 | Nissan Chemical Industries, Ltd. | 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators |
| US8134013B2 (en) | 2004-12-14 | 2012-03-13 | Nissan Chemical Industries, Ltd. | Amide compound and thrombopoietin receptor activator |
| MX2008000462A (es) * | 2005-07-14 | 2008-03-10 | Irm Llc | Compuestos heterotetraciclicos como mimeticos de tpo. |
| WO2007010954A1 (en) | 2005-07-15 | 2007-01-25 | Nissan Chemical Industries, Ltd. | Thiophene compounds and thrombopoietin receptor activators |
| KR101290484B1 (ko) | 2005-07-20 | 2013-07-26 | 닛산 가가쿠 고교 가부시키 가이샤 | 피라졸 화합물 및 트롬보포이에틴 수용체 활성화제 |
| KR20080035700A (ko) * | 2005-08-15 | 2008-04-23 | 아이알엠 엘엘씨 | Ｔｐｏ 모방체로서의 화합물 및 조성물 |
| JP5205967B2 (ja) | 2005-11-07 | 2013-06-05 | 日産化学工業株式会社 | ヒドラジド化合物及びトロンボポエチンレセプター活性化剤 |
| JP5157900B2 (ja) | 2006-06-07 | 2013-03-06 | 日産化学工業株式会社 | 含窒素ヘテロ環化合物及びトロンボポエチンレセプター活性化剤 |
| JP5054770B2 (ja) | 2006-07-11 | 2012-10-24 | デウン ファーマシューティカル カンパニー リミテッド | 新規のビアリールベンゾイミダゾール誘導体及びこれを含む医薬組成物 |
| KR20100019470A (ko) | 2007-04-30 | 2010-02-18 | 아보트 러보러터리즈 | 디아실글리세롤 ｏ-아실트랜스퍼라제 타입 １ 효소의 억제제 |
| CN101481352A (zh) | 2008-01-10 | 2009-07-15 | 上海恒瑞医药有限公司 | 双环取代吡唑酮偶氮类衍生物、其制备方法及其在医药上的应用 |
| PE20100362A1 (es) | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
| CN101921232A (zh) | 2009-06-11 | 2010-12-22 | 上海恒瑞医药有限公司 | 双环取代吡唑酮偶氮类衍生物的盐,其制备方法及其在医药上的应用 |
| WO2012102937A2 (en) | 2011-01-25 | 2012-08-02 | Irm Llc | Compounds that expand hematopoietic stem cells |
| EP2788476B1 (de) | 2011-12-08 | 2019-05-22 | Fred Hutchinson Cancer Research Center | Zusammensetzungen und verfahren zur erhöhten erzeugung von hämatopoietischen stamm-/vorläuferzellen |
| EP2807165B1 (de) | 2012-01-27 | 2019-05-15 | Université de Montréal | Pyrimido-[4,5-b-]indolderivate und verwendung davon in der expansion von hämatopoetischen stammzellen |
| JP6762233B2 (ja) | 2014-04-22 | 2020-09-30 | ウニヴェルシテ ド モントリオールＵｎｉｖｅｒｓｉｔｅ Ｄｅ Ｍｏｎｔｒｅａｌ | 化合物および造血幹細胞および／または造血前駆細胞の増大におけるその使用 |
| JP6658535B2 (ja) | 2014-10-31 | 2020-03-04 | 日産化学株式会社 | リガンド結合繊維及び当該繊維を用いた細胞培養基材 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE193350C (de) * | ||||
| US851444A (en) * | 1905-11-13 | 1907-04-23 | Agfa Ag | Amido-oxy-sulfonic acid of phenylnaphthimidazol and process of making same. |
| US4435417A (en) * | 1981-02-20 | 1984-03-06 | Gruppo Lepetit S.P.A. | Antiinflammatory 3H-naphtho[1,2-d]imidazoles |
| DE4126612A1 (de) * | 1990-08-14 | 1992-02-20 | Ciba Geigy Ag | Reaktivfarbstoffe, deren herstellung und verwendung |
| PT98673B (pt) * | 1990-08-15 | 1999-01-29 | British Bio Technology | Processo para a preparacao de compostos que sao antagonistas do factor de activacao de plaquetas por exemplo derivados de benzimidazole e de seus intermediarios |
-
2000
- 2000-12-06 ES ES00984123T patent/ES2275567T3/es not_active Expired - Lifetime
- 2000-12-06 AU AU20799/01A patent/AU2079901A/en not_active Abandoned
- 2000-12-06 EP EP00984123A patent/EP1244446B1/de not_active Expired - Lifetime
- 2000-12-06 JP JP2001541505A patent/JP2003515560A/ja active Pending
- 2000-12-06 WO PCT/US2000/033432 patent/WO2001039773A1/en not_active Ceased
- 2000-12-06 AT AT00984123T patent/ATE344031T1/de not_active IP Right Cessation
- 2000-12-06 DE DE60031714T patent/DE60031714T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2275567T3 (es) | 2007-06-16 |
| EP1244446B1 (de) | 2006-11-02 |
| JP2003515560A (ja) | 2003-05-07 |
| EP1244446A1 (de) | 2002-10-02 |
| WO2001039773A1 (en) | 2001-06-07 |
| DE60031714T2 (de) | 2007-09-06 |
| EP1244446A4 (de) | 2003-01-08 |
| AU2079901A (en) | 2001-06-12 |
| DE60031714D1 (de) | 2006-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |