ATE345813T1 - Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat - Google Patents

Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat

Info

Publication number: ATE345813T1
Authority: AT; Austria
Prior art keywords: membrane; membranes; vaccine; viruses; proteins
Prior art date: 1997-09-18

Application number

AT98947150T

Other languages

English (en)

Inventor

Dennis T Brown

Racquel Hernandez

Original Assignee

Res Dev Foundation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-18

Filing date

1998-09-18

Publication date

2006-12-15

1998-09-18 Application filed by Res Dev Foundation filed Critical Res Dev Foundation

2006-12-15 Application granted granted Critical

2006-12-15 Publication of ATE345813T1 publication Critical patent/ATE345813T1/de

Links

239000012528 membrane Substances 0.000 title abstract 9
241000700605 Viruses Species 0.000 title abstract 5
229960005486 vaccine Drugs 0.000 title abstract 5
230000035772 mutation Effects 0.000 title abstract 3
238000001228 spectrum Methods 0.000 title 1
239000000758 substrate Substances 0.000 title 1
238000000034 method Methods 0.000 abstract 3
102000004169 proteins and genes Human genes 0.000 abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 3
102000012750 Membrane Glycoproteins Human genes 0.000 abstract 2
108010090054 Membrane Glycoproteins Proteins 0.000 abstract 2
210000004027 cell Anatomy 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
241000238631 Hexapoda Species 0.000 abstract 1
241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
230000037430 deletion Effects 0.000 abstract 1
238000012217 deletion Methods 0.000 abstract 1
230000002209 hydrophobic effect Effects 0.000 abstract 1
210000004962 mammalian cell Anatomy 0.000 abstract 1
102000035160 transmembrane proteins Human genes 0.000 abstract 1
108091005703 transmembrane proteins Proteins 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36161—Methods of inactivation or attenuation

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Immunology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Engineering & Computer Science (AREA)
Mycology (AREA)
Epidemiology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT98947150T 1997-09-18 1998-09-18 Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat ATE345813T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5966897P	1997-09-18	1997-09-18

Publications (1)

Publication Number	Publication Date
ATE345813T1 true ATE345813T1 (de)	2006-12-15

Family

ID=22024455

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98947150T ATE345813T1 (de)	1997-09-18	1998-09-18	Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat

Country Status (15)

Country	Link
US (1)	US6306401B1 (de)
EP (1)	EP1037603B1 (de)
JP (1)	JP4318399B2 (de)
KR (1)	KR20010024148A (de)
CN (1)	CN1284859C (de)
AT (1)	ATE345813T1 (de)
AU (1)	AU737088B2 (de)
CA (1)	CA2302809C (de)
DE (1)	DE69836499T2 (de)
IL (2)	IL134978A0 (de)
NZ (1)	NZ503128A (de)
RU (1)	RU2218403C2 (de)
TW (1)	TW589381B (de)
WO (1)	WO1999013818A2 (de)
ZA (1)	ZA988446B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7335363B2 (en)	1997-09-18	2008-02-26	Research Development Foundation	Membrane virus host range mutations and their uses as vaccine substrates
US7128915B2 (en) *	1997-09-18	2006-10-31	Research Development Foundation	Membrane virus host range mutations and their uses as vaccine substrates
US6589533B1 (en) *	1997-09-18	2003-07-08	Research Development Foundation	Genetically-engineered alphaviruses, flaviviruses, and bunyaviruses with modified envelope transmembrane glycoproteins and altered host-range phenotype
JP2002523053A (ja) *	1998-07-30	2002-07-30	ジョーンズホプキンスユニバーシティースクールオブメディシン	標的化されたアルファウイルスおよびアルファウイルスベクター
CA2611056C (en)	2005-06-01	2016-06-28	California Institute Of Technology	Method of targeted gene delivery using viral vectors
CN100427918C (zh) *	2006-06-05	2008-10-22	中国科学院南海海洋研究所	一种海水鱼类卵子电镜扫描样品制备方法
BRPI0714495B8 (pt)	2006-07-21	2021-05-25	California Inst Of Techn	lentivírus deficiente para replicação recombinante pseudotipado
KR101790187B1 (ko)	2009-07-24	2017-10-25	이뮨 디자인 코포레이션	신드비스 바이러스 외피 당단백질로 가성형태화된 렌티바이러스 벡터
US10238734B2 (en)	2010-03-23	2019-03-26	The Regents Of The University Of California	Compositions and methods for self-adjuvanting vaccines against microbes and tumors
BR112012024224A2 (pt) *	2010-03-24	2016-11-29	Arbovax Inc	mutações da faixa de hospedeiro de flavivírus e seu uso.
WO2012003320A2 (en)	2010-07-01	2012-01-05	Research Development Foundation	Flavivirus host-range mutations and uses thereof
DK2831095T3 (en)	2012-03-30	2019-02-18	Immune Design Corp	LENTIVIRAL VECTOR PARTICLES WITH IMPROVED TRANSDUCTION EFFICIENCY FOR CELL EXPRESSING DC SIGN
US9713635B2 (en)	2012-03-30	2017-07-25	Immune Design Corp.	Materials and methods for producing improved lentiviral vector particles
US8323662B1 (en)	2012-03-30	2012-12-04	Immune Design Corp.	Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
US8895028B2 (en) *	2012-07-20	2014-11-25	Arbovax, Inc.	Methods and compositions for dengue virus 3 (DV3) infectious clone
US9701719B2 (en)	2012-09-27	2017-07-11	Research Development Foundation	Attenuated Chikungunya virus
AR107262A1 (es)	2016-01-27	2018-04-11	Lilly Co Eli	Inactivación de patógenos por delipidación
CN109943592B (zh) *	2019-04-29	2020-11-17	华中农业大学	含猪伪狂犬病病毒gD蛋白基因的重组杆状病毒转移载体、重组杆状病毒及制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5026686A (en) *	1989-02-01	1991-06-25	Washington University	Antiviral peptides

1998
- 1998-09-16 ZA ZA9808446A patent/ZA988446B/xx unknown
- 1998-09-18 DE DE69836499T patent/DE69836499T2/de not_active Expired - Lifetime
- 1998-09-18 KR KR1020007002912A patent/KR20010024148A/ko not_active Ceased
- 1998-09-18 NZ NZ503128A patent/NZ503128A/en not_active IP Right Cessation
- 1998-09-18 JP JP2000511447A patent/JP4318399B2/ja not_active Expired - Fee Related
- 1998-09-18 US US09/157,270 patent/US6306401B1/en not_active Expired - Lifetime
- 1998-09-18 AT AT98947150T patent/ATE345813T1/de not_active IP Right Cessation
- 1998-09-18 CN CNB988092484A patent/CN1284859C/zh not_active Expired - Fee Related
- 1998-09-18 EP EP98947150A patent/EP1037603B1/de not_active Expired - Lifetime
- 1998-09-18 AU AU93996/98A patent/AU737088B2/en not_active Ceased
- 1998-09-18 IL IL13497898A patent/IL134978A0/xx active IP Right Grant
- 1998-09-18 RU RU2000109569/13A patent/RU2218403C2/ru not_active IP Right Cessation
- 1998-09-18 CA CA2302809A patent/CA2302809C/en not_active Expired - Fee Related
- 1998-09-18 WO PCT/US1998/019556 patent/WO1999013818A2/en not_active Ceased
- 1998-10-13 TW TW087116968A patent/TW589381B/zh not_active IP Right Cessation
2000
- 2000-03-09 IL IL134978A patent/IL134978A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL134978A0 (en)	2001-05-20
ZA988446B (en)	2000-03-22
JP2003525564A (ja)	2003-09-02
DE69836499D1 (de)	2007-01-04
DE69836499T2 (de)	2007-10-11
NZ503128A (en)	2001-08-31
IL134978A (en)	2008-03-20
AU9399698A (en)	1999-04-05
AU737088B2 (en)	2001-08-09
CA2302809A1 (en)	1999-03-25
HK1033544A1 (en)	2001-09-07
US6306401B1 (en)	2001-10-23
CN1553961A (zh)	2004-12-08
WO1999013818A2 (en)	1999-03-25
WO1999013818A3 (en)	2003-12-04
TW589381B (en)	2004-06-01
CN1284859C (zh)	2006-11-15
KR20010024148A (ko)	2001-03-26
CA2302809C (en)	2011-08-09
EP1037603A4 (de)	2004-03-17
EP1037603B1 (de)	2006-11-22
JP4318399B2 (ja)	2009-08-19
RU2218403C2 (ru)	2003-12-10
EP1037603A1 (de)	2000-09-27

Legal Events

Date	Code	Title	Description
2007-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69836499D1 (de)	2007-01-04	Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat
Hernández et al.	2017	The hallmarks of cell-cell fusion
DE69434578D1 (de)	2006-01-26	Expressionsvektoren die für bispezifische Proteine kodieren, und Verfahren zur Herstellung von biologisch-aktiven bispezifischen Fusionsproteine in Zellen von Säugertieren
ATE278024T1 (de)	2004-10-15	Methode zur herstellung von rekombinanten zellen
WO2003068947A8 (en)	2003-10-23	Assay electrodes having immobilized lipid/protein layers and methods of making and using the same
Knowles et al.	1994	Cooperative action between band 3 and glycophorin A in human erythrocytes: immobilization of band 3 induced by antibodies to glycophorin A
DK457587A (da)	1987-11-02	Fremgangsmaade til fremstilling af et protein af faktor viii:c-typen
ATE500331T1 (de)	2011-03-15	Verfahren zur gleichzeitigen herstellung von multiplen proteinen; vektoren und zellen, die hierfür verwendung finden
ATE272109T1 (de)	2004-08-15	Rekombinante collagenase typ i aus clostridium histolyticum und ihre verwendung zur isolierung von zellen und zellverbänden
ATE213271T1 (de)	2002-02-15	Verfahren zur herstellung von rekombinanten proteinen in e. coli mittels hochzelldichte- fermentation
DE69836082D1 (de)	2006-11-16	Membranproteine aus säugetierzellen; verwandte reagentien
Zipperle et al.	2010	Identification of key residues in virulent canine distemper virus hemagglutinin that control CD150/SLAM-binding activity
DE69939330D1 (de)	2008-09-25	Wachstumsfaktor-homologe zvegf-3
BR9811675A (pt)	2000-09-19	Genes isolados para proteìna da membrana de célula dentrìtica
Zapf et al.	2015	Synthesis and Functional Reconstitution of Light‐Harvesting Complex II into Polymeric Membrane Architectures
WO2022108832A1 (en)	2022-05-27	Increased voltage-gated sodium channel alpha protein subunit expression through viral 2a-mediated co-expression of nav beta subunits
BR112023011689A2 (pt)	2023-10-31	Método para obter uma célula produtora de anticorpos, anticorpo, e, célula hospedeira de mamífero
Ocklind et al.	1980	Different cell surface glycoproteins are involved in cell—cell and cell—collagen adhesion of rat hepatocytes
Kajstura et al.	1993	Disruption of microtubules induces formation of actin fibrils in density-inhibited 3T3 cells.
ATE196165T1 (de)	2000-09-15	Methoden zur herstellung von protein c
DE60216721D1 (de)	2007-01-25	Verfahren zum Nachweis von Protein-Proteininteraktionen in Membranen
Kimura	1973	Further evidence of the similarity of microtubule protein from mitotic apparatus and sperm tail of the sea urchin, as a substrate in thiol-disulfide exchange reaction
WO1999047673A3 (en)	1999-11-18	Isolated mammalian membrane protein genes and related reagents
DE69631624D1 (de)	2004-04-01	Antikörper gegen menschliches restrictin
Yoneda	2000	New steps toward the nucleocytoplasmic traffic of macromolecules