ATE346162T1 - HOCHSENSITIVER NACHWEIS VON BIOMOLEKÜLEN MITTELS ßPHAGE DISPLAYß - Google Patents

HOCHSENSITIVER NACHWEIS VON BIOMOLEKÜLEN MITTELS ßPHAGE DISPLAYß

Info

Publication number
ATE346162T1
ATE346162T1 AT00926011T AT00926011T ATE346162T1 AT E346162 T1 ATE346162 T1 AT E346162T1 AT 00926011 T AT00926011 T AT 00926011T AT 00926011 T AT00926011 T AT 00926011T AT E346162 T1 ATE346162 T1 AT E346162T1
Authority
AT
Austria
Prior art keywords
phage
ßphage
displayß
biomolecules
target biomolecule
Prior art date
Application number
AT00926011T
Other languages
English (en)
Inventor
Carl R Merril
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE346162T1 publication Critical patent/ATE346162T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT00926011T 1999-04-14 2000-04-13 HOCHSENSITIVER NACHWEIS VON BIOMOLEKÜLEN MITTELS ßPHAGE DISPLAYß ATE346162T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12921599P 1999-04-14 1999-04-14

Publications (1)

Publication Number Publication Date
ATE346162T1 true ATE346162T1 (de) 2006-12-15

Family

ID=22438929

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00926011T ATE346162T1 (de) 1999-04-14 2000-04-13 HOCHSENSITIVER NACHWEIS VON BIOMOLEKÜLEN MITTELS ßPHAGE DISPLAYß

Country Status (8)

Country Link
US (1) US6740492B2 (de)
EP (1) EP1169473B1 (de)
JP (1) JP2002541818A (de)
AT (1) ATE346162T1 (de)
AU (1) AU778776B2 (de)
CA (1) CA2368875A1 (de)
DE (1) DE60031965D1 (de)
WO (1) WO2000061790A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2360282A (en) * 2000-03-17 2001-09-19 Bioinvent Int Ab Making and using micro-arrays of biological materials
WO2003010198A1 (en) * 2001-07-26 2003-02-06 Kenton Srl Identification of specific tumour antigens by selection of cdna libraries with sera and use of said antigens in diagnostic techniques
WO2003011902A1 (en) * 2001-07-27 2003-02-13 Kenton S.R.L. Identification of specific tumour antigens by selection of cdna libraries with sera
MXPA05002934A (es) * 2002-09-18 2006-02-24 Univ Pennsylvania Composiciones, metodos y kits para deteccion de un antigeno en una celula y en una mezcla biologica.
GB0304832D0 (en) * 2003-03-04 2003-04-09 Secr Defence Assay method
US8173002B2 (en) * 2005-02-24 2012-05-08 Life Technologies Corporation Electro-blotting devices, systems, and kits, and methods for their use
EP1885853A2 (de) 2005-05-27 2008-02-13 Guild Associates, Inc. Biologisches detektionssystem und -verfahren
US8066866B2 (en) * 2005-10-17 2011-11-29 Lifescan, Inc. Methods for measuring physiological fluids
WO2007064462A1 (en) * 2005-11-29 2007-06-07 The Trustees Of The University Of Pennsylvania Phage particle diagnostic reagents
US20100044229A1 (en) * 2008-07-11 2010-02-25 Life Technologies Corporation Electrophoretically Enhanced Detection of Analytes on a Solid Support
USD738527S1 (en) 2013-05-28 2015-09-08 Life Technologies Corporation Electroblotting apparatus
TWI570243B (zh) * 2015-11-03 2017-02-11 國立清華大學 噬菌體之篩選裝置及方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
GB9104411D0 (en) * 1991-03-01 1991-04-17 Elchrom Limited Improvement of gel composition in gels for submerged gel electrophoresis
BE1006312A3 (fr) * 1991-11-29 1994-07-19 Univ Catholique Louvain Procede de selection de microorganismes recombinants comportant a leur surface au moins une molecule a activite enzymatique.
US5650267A (en) * 1993-04-27 1997-07-22 Symbiotech, Inc. Method of detecting compounds utilizing genetically modified lambdoid bacteriophage
US5679510A (en) * 1993-04-27 1997-10-21 Hybridon, Inc. Quantitative detection of specific nucleic acid sequences using lambdoid bacteriophages linked by oligonucleotides to solid support
US6027877A (en) * 1993-11-04 2000-02-22 Gene Check, Inc. Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification
US5702892A (en) * 1995-05-09 1997-12-30 The United States Of America As Represented By The Department Of Health And Human Services Phage-display of immunoglobulin heavy chain libraries
IL114149A0 (en) * 1995-06-14 1995-10-31 Yeda Res & Dev Modified avidin and streptavidin molecules and use thereof
AU1127097A (en) * 1995-12-15 1997-07-14 Pharmacia & Upjohn Company Method for the simultaneous detection of a therapeutic target for a disease state and its neutralizing antibody-like molecule
DK0934526T3 (da) * 1996-10-08 2003-05-05 Bisys B V U Fremgangsmåder og midler til udvælgelse af peptider og proteiner, der har specifik affinitet til et mål

Also Published As

Publication number Publication date
AU4461200A (en) 2000-11-14
DE60031965D1 (de) 2007-01-04
JP2002541818A (ja) 2002-12-10
AU778776B2 (en) 2004-12-23
US20020110806A1 (en) 2002-08-15
US6740492B2 (en) 2004-05-25
EP1169473A1 (de) 2002-01-09
WO2000061790A1 (en) 2000-10-19
EP1169473B1 (de) 2006-11-22
CA2368875A1 (en) 2000-10-19

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