ATE34661T1 - Verbindungen zur verminderung des lipidspiegels. - Google Patents

Verbindungen zur verminderung des lipidspiegels.

Info

Publication number: ATE34661T1
Authority: AT; Austria
Prior art keywords: thioxomethyl; napthalenyl; methylglycine; methoxy; derivatives
Prior art date: 1983-08-01

Application number

AT84304919T

Other languages

English (en)

Inventor

Mary-Ann Kallai-Sanfacon

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-08-01

Filing date

1984-07-19

Publication date

1988-06-15

1984-07-19 Application filed by American Home Prod filed Critical American Home Prod

1988-06-15 Application granted granted Critical

1988-06-15 Publication of ATE34661T1 publication Critical patent/ATE34661T1/de

Links

150000002632 lipids Chemical class 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 2
YQHPVWRRSORYIV-UHFFFAOYSA-N 2-(naphthalene-1-carbonylamino)acetic acid Chemical class C1=CC=C2C(C(=O)NCC(=O)O)=CC=CC2=C1 YQHPVWRRSORYIV-UHFFFAOYSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000003524 antilipemic agent Substances 0.000 abstract 1
150000007529 inorganic bases Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
LUBHDINQXIHVLS-UHFFFAOYSA-N tolrestat Chemical compound OC(=O)CN(C)C(=S)C1=CC=CC2=C(C(F)(F)F)C(OC)=CC=C21 LUBHDINQXIHVLS-UHFFFAOYSA-N 0.000 abstract 1
125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Thiazole And Isothizaole Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Steroid Compounds (AREA)

AT84304919T 1983-08-01 1984-07-19 Verbindungen zur verminderung des lipidspiegels. ATE34661T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/518,997 US4492706A (en)	1983-08-01	1983-08-01	Method of lowering lipid levels
EP84304919A EP0132994B1 (de)	1983-08-01	1984-07-19	Verbindungen zur Verminderung des Lipidspiegels

Publications (1)

Publication Number	Publication Date
ATE34661T1 true ATE34661T1 (de)	1988-06-15

Family

ID=24066357

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT84304919T ATE34661T1 (de)	1983-08-01	1984-07-19	Verbindungen zur verminderung des lipidspiegels.

Country Status (9)

Country	Link
US (1)	US4492706A (de)
EP (1)	EP0132994B1 (de)
JP (1)	JPS6056920A (de)
AT (1)	ATE34661T1 (de)
BE (1)	BE900277A (de)
DE (1)	DE3428230A1 (de)
IT (1)	IT1206130B (de)
PH (1)	PH21601A (de)
ZA (1)	ZA845723B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0310931A3 (de) *	1987-10-08	1990-10-03	Ethyl Corporation	Hühnerfutter
JPH01263367A (ja) *	1988-04-14	1989-10-19	Kajima Corp	ダイビングプール
US5972685A (en) *	1988-07-21	1999-10-26	Iowa State University Research Foundation, Inc.	Oral administration of coprostanol producing microorganisms to humans to decrease plasma cholesterol concentration
US4921710A (en) *	1988-07-21	1990-05-01	Iowa State University Research Foundation, Inc.	Method of converting cholesterol in food to coprostanol
JP2551951Y2 (ja) *	1990-09-18	1997-10-27	三菱自動車工業株式会社	レーザ焼入処理した内面を有するシリンダ
US5391551A (en) *	1993-05-10	1995-02-21	Pfizer Inc.	Method of lowering blood lipid levels
US5674488A (en) *	1994-10-07	1997-10-07	Reich; John J.	Method for prevention and treatment of hyperchlolesterolemia by in vivo hydrogenation of cholesterol
IL120264A0 (en) *	1996-02-29	1997-06-10	Pfizer	Method of reducing tissue damage associated with non-cardiac ischemia
AU2112699A (en) *	1998-01-12	1999-07-26	Lipogenics, Inc.	Methods for treating diabetic dyslipidemia using tocotrienols

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1191156A (en) *	1981-10-15	1985-07-30	Francesco Bellini	N-((6-(lower alkoxy)-5-(trifluoromethylthio)-1- naphthalenyl)-thioxomethyl)-n-(lower alkyl)glycines
AU544067B2 (en) *	1981-03-02	1985-05-16	Wyeth-Ayerst Canada Inc.	Thioamides and amides. treatment of diabetes
CA1176269A (en) *	1981-03-02	1984-10-16	Kazimir Sestanj	N-naphthoylglycine derivatives
US4446150A (en) *	1982-09-21	1984-05-01	Ayerst, Mckenna & Harrison, Inc.	Naphthalenylthiazole derivatives

1983
- 1983-08-01 US US06/518,997 patent/US4492706A/en not_active Expired - Lifetime
1984
- 1984-07-19 AT AT84304919T patent/ATE34661T1/de not_active IP Right Cessation
- 1984-07-19 EP EP84304919A patent/EP0132994B1/de not_active Expired
- 1984-07-24 ZA ZA845723A patent/ZA845723B/xx unknown
- 1984-07-31 JP JP59162772A patent/JPS6056920A/ja active Pending
- 1984-07-31 DE DE3428230A patent/DE3428230A1/de not_active Withdrawn
- 1984-08-01 BE BE0/213430A patent/BE900277A/fr not_active IP Right Cessation
- 1984-08-01 IT IT8422178A patent/IT1206130B/it active
- 1984-08-01 PH PH31058A patent/PH21601A/en unknown

Also Published As

Publication number	Publication date
DE3428230A1 (de)	1985-02-21
US4492706A (en)	1985-01-08
EP0132994B1 (de)	1988-06-01
ZA845723B (en)	1986-03-26
IT1206130B (it)	1989-04-14
PH21601A (en)	1987-12-11
EP0132994A1 (de)	1985-02-13
IT8422178A0 (it)	1984-08-01
JPS6056920A (ja)	1985-04-02
BE900277A (fr)	1985-02-01

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Legal Events

Date	Code	Title	Description
1988-09-15	UEP	Publication of translation of european patent specification
1990-04-15	REN	Ceased due to non-payment of the annual fee