ATE346863T1 - Verwendung von eif4e-bindungsreagenzien in der therapie - Google Patents
Verwendung von eif4e-bindungsreagenzien in der therapieInfo
- Publication number
- ATE346863T1 ATE346863T1 AT00940589T AT00940589T ATE346863T1 AT E346863 T1 ATE346863 T1 AT E346863T1 AT 00940589 T AT00940589 T AT 00940589T AT 00940589 T AT00940589 T AT 00940589T AT E346863 T1 ATE346863 T1 AT E346863T1
- Authority
- AT
- Austria
- Prior art keywords
- therapy
- binding reagents
- eif4e binding
- eif4e
- xxyxxx
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 102000005233 Eukaryotic Initiation Factor-4E Human genes 0.000 title 1
- 108060002636 Eukaryotic Initiation Factor-4E Proteins 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 238000003782 apoptosis assay Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000005522 programmed cell death Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9914480.0A GB9914480D0 (en) | 1999-06-21 | 1999-06-21 | Use of peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE346863T1 true ATE346863T1 (de) | 2006-12-15 |
Family
ID=10855771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00940589T ATE346863T1 (de) | 1999-06-21 | 2000-06-21 | Verwendung von eif4e-bindungsreagenzien in der therapie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7141541B1 (de) |
| EP (1) | EP1189936B1 (de) |
| JP (1) | JP2003502440A (de) |
| AT (1) | ATE346863T1 (de) |
| DE (1) | DE60032143D1 (de) |
| GB (1) | GB9914480D0 (de) |
| WO (1) | WO2000078803A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030144190A1 (en) * | 1999-12-02 | 2003-07-31 | Nahum Sonenberg | Method of modulating and antiapoptotic and antiapoptotic pathways in cells |
| US6759394B2 (en) | 2001-07-26 | 2004-07-06 | Board Of Supervisors Of La. State Un. & Agricultural And Mechanical College | Cancer gene therapy based on translational control of a suicide gene |
| WO2009083188A2 (en) * | 2007-12-28 | 2009-07-09 | Fovea Pharmaceuticals | Compositions and methods for prophylaxis and treatment of cellular degenerative disorders |
| FR2942798B1 (fr) * | 2009-03-05 | 2011-04-08 | Centre Nat Rech Scient | Peptides utilisables pour le traitement de la leucemie lymphoide chronique |
| EP2569327B1 (de) * | 2010-04-27 | 2016-05-25 | Agency For Science, Technology And Research | Eif4e-bindende peptide |
| EP2870174A1 (de) | 2012-07-09 | 2015-05-13 | F. Hoffmann-La Roche AG | Zellenpenetrierende, gegen eif4e gerichtete peptide |
| TW202114681A (zh) | 2019-07-02 | 2021-04-16 | 美商eFFECTOR醫療公司 | 轉譯抑制劑及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994018345A1 (en) | 1993-02-05 | 1994-08-18 | Affymax Technologies N.V. | Receptor-binding antiproliferative peptides |
| US5622852A (en) | 1994-10-31 | 1997-04-22 | Washington University | Bcl-x/Bcl-2 associated cell death regulator |
| WO1998039357A1 (en) | 1997-03-05 | 1998-09-11 | The Regents Of The University Of California | Method of alleviating neuropathic pain |
| US6610508B1 (en) * | 1999-03-08 | 2003-08-26 | Anadys Pharmaceuticals, Inc. | Translation driver system and methods for use thereof |
-
1999
- 1999-06-21 GB GBGB9914480.0A patent/GB9914480D0/en not_active Ceased
-
2000
- 2000-06-21 WO PCT/GB2000/002414 patent/WO2000078803A2/en not_active Ceased
- 2000-06-21 JP JP2001505561A patent/JP2003502440A/ja not_active Withdrawn
- 2000-06-21 DE DE60032143T patent/DE60032143D1/de not_active Expired - Lifetime
- 2000-06-21 US US10/019,198 patent/US7141541B1/en not_active Expired - Fee Related
- 2000-06-21 EP EP00940589A patent/EP1189936B1/de not_active Expired - Lifetime
- 2000-06-21 AT AT00940589T patent/ATE346863T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000078803A2 (en) | 2000-12-28 |
| GB9914480D0 (en) | 1999-08-18 |
| EP1189936A2 (de) | 2002-03-27 |
| JP2003502440A (ja) | 2003-01-21 |
| EP1189936B1 (de) | 2006-11-29 |
| DE60032143D1 (de) | 2007-01-11 |
| WO2000078803A3 (en) | 2001-07-26 |
| US7141541B1 (en) | 2006-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |