ATE347912T1 - IONIC AND NON-IONIC RADIOGRAPHIC CONTRAST AGENT FOR USE IN COMBINED X-ray and nuclear magnetic resonance imaging diagnostics - Google Patents

IONIC AND NON-IONIC RADIOGRAPHIC CONTRAST AGENT FOR USE IN COMBINED X-ray and nuclear magnetic resonance imaging diagnostics

Info

Publication number
ATE347912T1
ATE347912T1 AT02758379T AT02758379T ATE347912T1 AT E347912 T1 ATE347912 T1 AT E347912T1 AT 02758379 T AT02758379 T AT 02758379T AT 02758379 T AT02758379 T AT 02758379T AT E347912 T1 ATE347912 T1 AT E347912T1
Authority
AT
Austria
Prior art keywords
ionic
ray
combined
magnetic resonance
nuclear magnetic
Prior art date
Application number
AT02758379T
Other languages
German (de)
Inventor
Silvio Aime
Alessandro Barge
Valentina Mainero
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Application granted granted Critical
Publication of ATE347912T1 publication Critical patent/ATE347912T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

The invention discloses the use of ionic and non-ionic radiographic contrast agents for combined X-ray and nuclear magnetic resonance (MRI) diagnostics.
AT02758379T 2001-08-03 2002-07-23 IONIC AND NON-IONIC RADIOGRAPHIC CONTRAST AGENT FOR USE IN COMBINED X-ray and nuclear magnetic resonance imaging diagnostics ATE347912T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI001706A ITMI20011706A1 (en) 2001-08-03 2001-08-03 IONIC AND NON-IONIC RADIOGRAPHIC CONTRAST AGENTS, USABLE FOR THE COMBINED DIAGNOSTIC INVESTIGATION THROUGH X-RAYS AND MAGNETIC RESONANCE

Publications (1)

Publication Number Publication Date
ATE347912T1 true ATE347912T1 (en) 2007-01-15

Family

ID=11448229

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02758379T ATE347912T1 (en) 2001-08-03 2002-07-23 IONIC AND NON-IONIC RADIOGRAPHIC CONTRAST AGENT FOR USE IN COMBINED X-ray and nuclear magnetic resonance imaging diagnostics

Country Status (9)

Country Link
US (1) US8211404B2 (en)
EP (1) EP1411992B1 (en)
JP (1) JP4310187B2 (en)
AT (1) ATE347912T1 (en)
DE (1) DE60216770T2 (en)
DK (1) DK1411992T3 (en)
ES (1) ES2278946T3 (en)
IT (1) ITMI20011706A1 (en)
WO (1) WO2003013616A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE529135T1 (en) 2004-03-11 2011-11-15 Mallinckrodt Llc X-RAY CONTRAST FORMULATION WITH A MIXTURE OF AN IODINATED MONOMER AND DIMER
DE102005028882A1 (en) * 2005-06-22 2007-01-04 Siemens Ag A solution and method for assisting imaging on a patient
EP1907873B1 (en) * 2005-07-21 2015-02-25 Johns Hopkins University Non-invasive mri measurement of tissue glycogen
EP2073723A4 (en) * 2006-10-10 2011-03-30 Mayo Foundation REDUCTION OF TOXICITY INDUCED BY A CONTRAST AGENT
ES2413160T3 (en) * 2007-10-12 2013-07-15 Ge Healthcare As Contrast agents
JP2011504939A (en) * 2007-11-07 2011-02-17 ジーイー・ヘルスケア・アクスイェ・セルスカプ Contrast agent
DE102007058220A1 (en) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft New metal complexes useful e.g. for manufacturing agent for X-ray diagnostics and magnetic resonance tomography-diagnostics of brain infarcts and liver tumor, and/or space-process in liver and abdomen tumors and musculoskeletal tumors
JP2011506286A (en) * 2007-12-05 2011-03-03 ジーイー・ヘルスケア・アクスイェ・セルスカプ Contrast agent
US8535642B2 (en) * 2008-02-27 2013-09-17 Ge Healthcare As Contrast agents
EP2243767A1 (en) * 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2541272A1 (en) * 1983-02-23 1984-08-24 Guerbet Sa BROMINE COMPOUNDS AND OPACIFIER PRODUCTS CONTAINING THEM
JPH10500999A (en) 1995-02-24 1998-01-27 ブラッコ リサーチ ソシエテ アノニム Liposomal suspensions as blood pool imaging contrast agents
US5648536A (en) * 1995-06-07 1997-07-15 Dunn; Thomas Jeffrey Process for producing ioversol
CN1221250C (en) * 1998-04-09 2005-10-05 阿莫萨姆保健公司 Use of particulate contrast agents in diagnostic imaging for studying physiological parameters
EP1178837A2 (en) * 1999-04-21 2002-02-13 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Method for enhancing contrast produced by mri
FR2794744B1 (en) 1999-06-09 2001-09-21 Guerbet Sa METAL COMPLEXES OF BICYCLIC POLYAMINOACIDS, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN MEDICAL IMAGING

Also Published As

Publication number Publication date
EP1411992A1 (en) 2004-04-28
ES2278946T3 (en) 2007-08-16
ITMI20011706A1 (en) 2003-02-03
EP1411992B1 (en) 2006-12-13
JP2005505527A (en) 2005-02-24
US8211404B2 (en) 2012-07-03
WO2003013616A8 (en) 2004-04-08
ITMI20011706A0 (en) 2001-08-03
US20050113675A1 (en) 2005-05-26
DK1411992T3 (en) 2007-04-10
WO2003013616A1 (en) 2003-02-20
DE60216770T2 (en) 2007-04-12
DE60216770D1 (en) 2007-01-25
JP4310187B2 (en) 2009-08-05

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