ATE348888T1 - Eine den gp41-zwischenzustand imitierende struktur bildendes polypeptid-antigen - Google Patents

Eine den gp41-zwischenzustand imitierende struktur bildendes polypeptid-antigen

Info

Publication number
ATE348888T1
ATE348888T1 AT02783174T AT02783174T ATE348888T1 AT E348888 T1 ATE348888 T1 AT E348888T1 AT 02783174 T AT02783174 T AT 02783174T AT 02783174 T AT02783174 T AT 02783174T AT E348888 T1 ATE348888 T1 AT E348888T1
Authority
AT
Austria
Prior art keywords
intermediate state
mimicing
polypeptide antigen
polypeptide
antigen forming
Prior art date
Application number
AT02783174T
Other languages
English (en)
Inventor
Michel Chevalier
Habib Raphaelle El
Tino Krell
Regis Sodoyer
Original Assignee
Sanofi Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0112806A external-priority patent/FR2830534B1/fr
Application filed by Sanofi Pasteur filed Critical Sanofi Pasteur
Application granted granted Critical
Publication of ATE348888T1 publication Critical patent/ATE348888T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02783174T 2001-10-05 2002-09-18 Eine den gp41-zwischenzustand imitierende struktur bildendes polypeptid-antigen ATE348888T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0112806A FR2830534B1 (fr) 2001-10-05 2001-10-05 Antigene polypeptidique formant une structure mimant l'etat intermediaire de gp41.
US34790901P 2001-11-07 2001-11-07

Publications (1)

Publication Number Publication Date
ATE348888T1 true ATE348888T1 (de) 2007-01-15

Family

ID=26213208

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02783174T ATE348888T1 (de) 2001-10-05 2002-09-18 Eine den gp41-zwischenzustand imitierende struktur bildendes polypeptid-antigen

Country Status (10)

Country Link
US (1) US6821723B2 (de)
EP (1) EP1442124B1 (de)
AT (1) ATE348888T1 (de)
CA (1) CA2462710C (de)
CY (1) CY1106017T1 (de)
DE (1) DE60216958T2 (de)
DK (1) DK1442124T3 (de)
ES (1) ES2275926T3 (de)
PT (1) PT1442124E (de)
WO (1) WO2003042388A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0422439D0 (en) * 2004-10-08 2004-11-10 European Molecular Biology Lab Embl Inhibitors of infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2781676B1 (fr) * 1998-07-31 2004-04-02 Pasteur Merieux Serums Vacc Trimere du produit d'expression du gene env de hiv
JP2003529319A (ja) * 1999-01-08 2003-10-07 キャロル ディ. ウエイス, HIV−1gp41を標的化する広範に中和する抗体を誘発する方法
DE60037450T2 (de) * 1999-12-16 2008-12-04 Whitehead Institute For Biomedical Research, Cambridge Fünf-helix protein
WO2001070262A2 (en) * 2000-03-17 2001-09-27 Panacos Pharmaceuticals, Inc. A method for generating immunogens that elicit neutralizing antibodies against fusion-active regions of hiv envelope proteins

Also Published As

Publication number Publication date
CY1106017T1 (el) 2011-04-06
DE60216958D1 (de) 2007-02-01
CA2462710C (en) 2011-05-17
DE60216958T2 (de) 2007-10-04
EP1442124A1 (de) 2004-08-04
PT1442124E (pt) 2007-02-28
ES2275926T3 (es) 2007-06-16
DK1442124T3 (da) 2007-04-10
WO2003042388A1 (fr) 2003-05-22
US6821723B2 (en) 2004-11-23
CA2462710A1 (en) 2003-05-22
US20030138445A1 (en) 2003-07-24
EP1442124B1 (de) 2006-12-20

Similar Documents

Publication Publication Date Title
DE60110822D1 (de) Zubereitung zur immunisierung gegen den aids-virus
ID30497A (id) Peptida hiv, antigen, komposisi vaksin, kit imunoasai dan metoda untuk mendeteksi antibodi yang diinduksi oleh hiv
BR9814487A (pt) "vacina"
WO2002020554A3 (en) Hiv peptides from conserved regions in gag p17 and 924 and their application in e.g. vaccines
TR199801722T2 (xx) Peptit imm�nojenler.
MA24638A1 (fr) Vaccin
ATE125157T1 (de) Methoden und zusammensetzungen zur impfung gegen hiv.
AP2002002592A0 (en) Vaccine for the prophylactic or therapeutic immunization against HIV.
DK2133100T3 (da) MTB32A-Antigen af Mycobacterium tuberculosis med inaktiveret aktivt sted og fusionsproteiner deraf
ES2194836T3 (es) Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana.
EA200700496A1 (ru) Инактивированная полиомиелитная вакцина, полученная из штамма сейбина вируса полиомиелита
WO2003015702A3 (en) Epitopes of human immunodeficiency virus-1
EP0881910A4 (de) Verwendung von immunokonjugaten zur erhöhung der effektivität von mehrstufigen kaskaden-impfstoffen
DE60222296D1 (de) Impfstoff von umhüllten viren und verfahren zu seiner herstellung
WO2001060404A3 (en) Use of opri lipoprotein from pseudomonas as a th1 inducing natural adjuvant for heterologous antigens
DE69327529D1 (de) Immunologisch mit HLA homologe HIV Protein Epitope
ATE185073T1 (de) Impfstoff zubereitungen
DE60216958D1 (de) Eine den gp41-zwischenzustand imitierende struktur bildendes polypeptid-antigen
WO2004053100A3 (en) Immunogenic mutant human immunodeficiency virus gp120 polypeptides, and methods of using same
DE69433057D1 (de) Peptide zur verwendung bei der impfung und induktion neutralisierender antikörper gegen das menschliche immunschwäche-virus
DK1368478T3 (da) Polypeptid, der fremkalder HIV-neutraliserende antistoffer
DE69233271D1 (de) Therapeutischer- und präventivimpfstoff gegen hiv
ATE134649T1 (de) Arzneimittel und verfahren zur behandlung von erworbenem immundefizienzsyndrom (aids) und aids- verwandtem komplex unter verwendung von karbohydratspezifischen antikörpern
JP2004532198A5 (de)
WO2002085409A3 (en) Methods and compositions for inducing an immune response to an antigen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1442124

Country of ref document: EP