ATE349212T1 - Mittel gegen krebs - Google Patents
Mittel gegen krebsInfo
- Publication number
- ATE349212T1 ATE349212T1 AT00962991T AT00962991T ATE349212T1 AT E349212 T1 ATE349212 T1 AT E349212T1 AT 00962991 T AT00962991 T AT 00962991T AT 00962991 T AT00962991 T AT 00962991T AT E349212 T1 ATE349212 T1 AT E349212T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- anticancer agents
- against cancer
- fibroblasts
- prodrugs
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 208000002260 Keloid Diseases 0.000 abstract 1
- 206010023330 Keloid scar Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000008640 diphenylmethylpiperazines Chemical class 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 210000001117 keloid Anatomy 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 208000005069 pulmonary fibrosis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28087499 | 1999-09-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE349212T1 true ATE349212T1 (de) | 2007-01-15 |
Family
ID=17631164
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05077245T ATE359788T1 (de) | 1999-09-30 | 2000-09-29 | Verwendung von diphenylmethylpiperazin-derivaten zur herstellung eines medikaments zur unterdrückung der proliferation von fibroblasten |
| AT00962991T ATE349212T1 (de) | 1999-09-30 | 2000-09-29 | Mittel gegen krebs |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05077245T ATE359788T1 (de) | 1999-09-30 | 2000-09-29 | Verwendung von diphenylmethylpiperazin-derivaten zur herstellung eines medikaments zur unterdrückung der proliferation von fibroblasten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6683083B1 (de) |
| EP (2) | EP1637140B1 (de) |
| AT (2) | ATE359788T1 (de) |
| AU (1) | AU776745B2 (de) |
| CA (1) | CA2385996C (de) |
| DE (2) | DE60032620T2 (de) |
| TW (1) | TWI289450B (de) |
| WO (1) | WO2001022968A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7879840B2 (en) * | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US7393652B2 (en) * | 2000-05-10 | 2008-07-01 | The Trustees Of Columbia University In The City Of New York | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) |
| US20040048780A1 (en) * | 2000-05-10 | 2004-03-11 | The Trustees Of Columbia University In The City Of New York | Method for treating and preventing cardiac arrhythmia |
| US20060293266A1 (en) * | 2000-05-10 | 2006-12-28 | The Trustees Of Columbia | Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure |
| US20040229781A1 (en) * | 2000-05-10 | 2004-11-18 | Marks Andrew Robert | Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias |
| US6489125B1 (en) * | 2000-05-10 | 2002-12-03 | The Trustees Of Columbia University In The City Of New York | Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor |
| US7718644B2 (en) * | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
| US8022058B2 (en) | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US7312044B2 (en) | 2003-03-07 | 2007-12-25 | The Trustees Of Columbia University In The City Of New York | Type 1 ryanodine receptor-based methods |
| US7544678B2 (en) * | 2002-11-05 | 2009-06-09 | The Trustees Of Columbia University In The City Of New York | Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) |
| US8710045B2 (en) * | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
| US7704990B2 (en) * | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US20070052304A1 (en) * | 2005-09-07 | 2007-03-08 | Philippe Masson | Multi-pattern high temperature superconducting motor using flux trapping and concentration |
| JP5318938B2 (ja) * | 2011-06-09 | 2013-10-16 | 株式会社アエタスファルマ | ジフェニルメチルピペラジン誘導体、及びそれを用いた医薬組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340821C (en) * | 1988-10-06 | 1999-11-16 | Nobuyuki Fukazawa | Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components |
| JP2651043B2 (ja) | 1990-07-10 | 1997-09-10 | 麒麟麦酒株式会社 | ジフェニルメチルピペラジン誘導体 |
| JP2518965B2 (ja) * | 1990-09-21 | 1996-07-31 | 三井東圧化学株式会社 | 新規ピリジン誘導体及びそれを有効成分として含有する制癌剤効果増強剤 |
-
2000
- 2000-09-29 AT AT05077245T patent/ATE359788T1/de active
- 2000-09-29 EP EP05077245A patent/EP1637140B1/de not_active Expired - Lifetime
- 2000-09-29 DE DE60032620T patent/DE60032620T2/de not_active Expired - Lifetime
- 2000-09-29 EP EP00962991A patent/EP1222924B1/de not_active Expired - Lifetime
- 2000-09-29 AU AU74498/00A patent/AU776745B2/en not_active Ceased
- 2000-09-29 US US10/089,718 patent/US6683083B1/en not_active Expired - Fee Related
- 2000-09-29 DE DE60034494T patent/DE60034494T2/de not_active Expired - Lifetime
- 2000-09-29 WO PCT/JP2000/006786 patent/WO2001022968A1/ja not_active Ceased
- 2000-09-29 AT AT00962991T patent/ATE349212T1/de active
- 2000-09-29 CA CA002385996A patent/CA2385996C/en not_active Expired - Fee Related
- 2000-09-30 TW TW089120410A patent/TWI289450B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60034494D1 (de) | 2007-05-31 |
| EP1222924A4 (de) | 2004-08-04 |
| DE60032620D1 (de) | 2007-02-08 |
| EP1222924B1 (de) | 2006-12-27 |
| DE60034494T2 (de) | 2008-01-03 |
| CA2385996A1 (en) | 2001-04-05 |
| US6683083B1 (en) | 2004-01-27 |
| AU7449800A (en) | 2001-04-30 |
| EP1637140B1 (de) | 2007-04-18 |
| EP1222924A1 (de) | 2002-07-17 |
| DE60032620T2 (de) | 2007-10-04 |
| AU776745B2 (en) | 2004-09-23 |
| EP1637140A1 (de) | 2006-03-22 |
| CA2385996C (en) | 2008-02-12 |
| TWI289450B (en) | 2007-11-11 |
| WO2001022968A1 (en) | 2001-04-05 |
| ATE359788T1 (de) | 2007-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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