ATE349456T1 - Herstellung von 2-18f-2-desoxy-d-glucose durch festphasensynthese - Google Patents

Herstellung von 2-18f-2-desoxy-d-glucose durch festphasensynthese

Info

Publication number
ATE349456T1
ATE349456T1 AT04743612T AT04743612T ATE349456T1 AT E349456 T1 ATE349456 T1 AT E349456T1 AT 04743612 T AT04743612 T AT 04743612T AT 04743612 T AT04743612 T AT 04743612T AT E349456 T1 ATE349456 T1 AT E349456T1
Authority
AT
Austria
Prior art keywords
desoxy
glucose
production
solid phase
phase synthesis
Prior art date
Application number
AT04743612T
Other languages
English (en)
Inventor
Lynda Jane Brown
Richard C D Brown
Harry John Wadsworth
Alexander Ge Jackson
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Application granted granted Critical
Publication of ATE349456T1 publication Critical patent/ATE349456T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Catalysts (AREA)
AT04743612T 2003-07-31 2004-07-29 Herstellung von 2-18f-2-desoxy-d-glucose durch festphasensynthese ATE349456T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0317920.7A GB0317920D0 (en) 2003-07-31 2003-07-31 Solid-phase synthesis

Publications (1)

Publication Number Publication Date
ATE349456T1 true ATE349456T1 (de) 2007-01-15

Family

ID=27799539

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04743612T ATE349456T1 (de) 2003-07-31 2004-07-29 Herstellung von 2-18f-2-desoxy-d-glucose durch festphasensynthese

Country Status (8)

Country Link
US (1) US7976824B2 (de)
EP (1) EP1648912B1 (de)
JP (1) JP4731477B2 (de)
AT (1) ATE349456T1 (de)
DE (1) DE602004003948T2 (de)
ES (1) ES2279403T3 (de)
GB (1) GB0317920D0 (de)
WO (1) WO2005012319A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
US7485283B2 (en) 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
US7824659B2 (en) * 2005-08-10 2010-11-02 Lantheus Medical Imaging, Inc. Methods of making radiolabeled tracers and precursors thereof
WO2009110984A2 (en) 2008-02-29 2009-09-11 Lantheus Medical Imaging, Inc. Contrast agents for applications including perfusion imaging
CA2729635A1 (en) * 2008-07-03 2010-01-07 Ananth Srinivasan Compounds and processes for production of radiopharmaceuticals
ES2770364T3 (es) 2009-04-15 2020-07-01 Lantheus Medical Imaging Inc Estabilización de composiciones radiofarmacéuticas utilizando ácido ascórbico
DE102010007097A1 (de) * 2010-02-06 2011-08-11 Matteo Scabini Konjugate aus [F-18]-Traegern mit bioaktiven, organischen Verbindungen und deren Darstellung
RU2631500C2 (ru) 2010-02-08 2017-09-25 Лантеус Медикал Имаджинг, Инк. Способы и устройство для синтезирования радиофармацевтических препаратов и их промежуточных продуктов
US9073802B2 (en) * 2010-02-12 2015-07-07 Tokyo Institute Of Technology Method for producing 18F-labeled compound and high molecular compound to be used in the method
KR101351878B1 (ko) 2010-12-14 2014-02-06 서강대학교산학협력단 １８ｆ 방사성의약품 제조를 위한 고체 지지체에 연결된 전구체 화합물, 이의 제조방법 및 응용
CN102775419B (zh) * 2011-05-13 2015-03-04 上海医药工业研究院 一种4,6-o-苄叉基-3-o-乙酰基-d-葡萄糖烯的制备方法
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
GB201405591D0 (en) * 2014-03-28 2014-05-14 Ge Healthcare Ltd Heatseal
JP7668480B2 (ja) 2021-01-19 2025-04-25 国立大学法人東京科学大学 放射性ハロゲン標識前駆体化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0206386A (pt) 2001-01-12 2005-04-26 Amersham Plc Ativador ligado a suporte, suporte ativado, kit, biblioteca de alvos ativados pelo suporte, suporte fortemente ácido, suporte sililador, método de fixar covalentemente um nucleófilo a um composto apresentando um grupo hidróxi ou uma cetona enolizável, e, reagente ligador
GB0115927D0 (en) 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
GB0115929D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase electrophilic fluorination

Also Published As

Publication number Publication date
JP2007500688A (ja) 2007-01-18
EP1648912B1 (de) 2006-12-27
WO2005012319A1 (en) 2005-02-10
JP4731477B2 (ja) 2011-07-27
DE602004003948T2 (de) 2007-10-11
GB0317920D0 (en) 2003-09-03
US20070274911A1 (en) 2007-11-29
DE602004003948D1 (de) 2007-02-08
EP1648912A1 (de) 2006-04-26
ES2279403T3 (es) 2007-08-16
US7976824B2 (en) 2011-07-12

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