ATE349694T1 - Vorrichtung zur automatischen elektrodenpositionierung - Google Patents
Vorrichtung zur automatischen elektrodenpositionierungInfo
- Publication number
- ATE349694T1 ATE349694T1 AT98919082T AT98919082T ATE349694T1 AT E349694 T1 ATE349694 T1 AT E349694T1 AT 98919082 T AT98919082 T AT 98919082T AT 98919082 T AT98919082 T AT 98919082T AT E349694 T1 ATE349694 T1 AT E349694T1
- Authority
- AT
- Austria
- Prior art keywords
- automatic electrode
- methods
- electrode positioning
- cell
- automatic
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 238000004070 electrodeposition Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Discharge Heating (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK49697 | 1997-05-01 | ||
| DK90297 | 1997-08-01 | ||
| DK115197 | 1997-10-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE349694T1 true ATE349694T1 (de) | 2007-01-15 |
Family
ID=27220731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98919082T ATE349694T1 (de) | 1997-05-01 | 1998-04-29 | Vorrichtung zur automatischen elektrodenpositionierung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6470226B1 (de) |
| EP (1) | EP0980523B1 (de) |
| JP (1) | JP2002507278A (de) |
| AT (1) | ATE349694T1 (de) |
| AU (1) | AU729397B2 (de) |
| CA (1) | CA2285279A1 (de) |
| DE (1) | DE69836736T2 (de) |
| DK (1) | DK0980523T3 (de) |
| IL (1) | IL131823A0 (de) |
| NZ (1) | NZ337814A (de) |
| WO (1) | WO1998050791A1 (de) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003046170A1 (en) * | 2001-11-27 | 2003-06-05 | Cellectricon Ab | A method for combined parallel agent delivery and electroporation for cell structures and use thereof |
| US7244349B2 (en) | 1997-12-17 | 2007-07-17 | Molecular Devices Corporation | Multiaperture sample positioning and analysis system |
| US20020144905A1 (en) | 1997-12-17 | 2002-10-10 | Christian Schmidt | Sample positioning and analysis system |
| WO1999031503A1 (de) | 1997-12-17 | 1999-06-24 | Horst Vogel | Positionierung und elektrophysiologische charakterisierung einzelner zellen und rekonstituierter membransysteme auf mikrostrukturierten trägern |
| GB9812783D0 (en) | 1998-06-12 | 1998-08-12 | Cenes Ltd | High throuoghput screen |
| AU775985B2 (en) * | 1998-12-05 | 2004-08-19 | Xention Limited | Interface patch clamping |
| JP3582390B2 (ja) * | 1999-01-13 | 2004-10-27 | 松下電器産業株式会社 | 微細物体の自動探索装置 |
| JP4620254B2 (ja) | 1999-04-19 | 2011-01-26 | イオンスコープ リミテッド | 光学顕微鏡法および細胞研究におけるその使用 |
| WO2001059447A1 (en) * | 2000-02-11 | 2001-08-16 | Yale University | Planar patch clamp electrodes |
| GB0006748D0 (en) * | 2000-03-21 | 2000-05-10 | Cenes Ltd | Improved interface patch clamping |
| US7011939B2 (en) * | 2000-03-22 | 2006-03-14 | Abbott Laboratories | Apparatus and method for electrophysiological testing |
| US7270730B2 (en) * | 2000-08-04 | 2007-09-18 | Essen Instruments, Inc. | High-throughput electrophysiological measurement system |
| US7067046B2 (en) | 2000-08-04 | 2006-06-27 | Essen Instruments, Inc. | System for rapid chemical activation in high-throughput electrophysiological measurements |
| US6461860B2 (en) * | 2001-01-25 | 2002-10-08 | Axon Instruments, Inc. | Alignment mechanism for two-electrode voltage-clamp perfusion chamber for electrophysiological testing of oocytes |
| FR2820756B1 (fr) * | 2001-02-09 | 2004-01-23 | Daniel Attias | Incubateur et procede d'incubation menageant l'organisme mis a incuber |
| US6815197B2 (en) * | 2001-02-16 | 2004-11-09 | Multi Channel System Mcs Gmbh | Apparatus for conducting electrophysiological measurements on cells |
| CA2441366A1 (en) | 2001-03-24 | 2002-10-03 | Aviva Biosciences Corporation | Biochips including ion transport detecting structures and methods of use |
| US20060029955A1 (en) | 2001-03-24 | 2006-02-09 | Antonio Guia | High-density ion transport measurement biochip devices and methods |
| EP1399479B1 (de) | 2001-06-06 | 2009-09-16 | Neurosearch A/S | Kationenleitende gaba-a-rezeptoren und deren verwendung |
| US20050158845A1 (en) * | 2001-08-06 | 2005-07-21 | Wikswo John P. | Device and methods for measuring the response of a least one cell to a medium |
| EP1434850A2 (de) * | 2001-09-05 | 2004-07-07 | Essen Instruments, Inc. | Elektrophysiologisches messsystem mit hohem durchsatz |
| WO2003029921A2 (en) * | 2001-09-28 | 2003-04-10 | University Of North Carolina At Chapel Hill | Methods and systems for three-dimensional motion control and tracking of a mechanically unattached magnetic probe |
| EP1451339A4 (de) | 2001-11-30 | 2005-01-05 | Bristol Myers Squibb Co | Flüssige schnittstellen-konfigurationen zur automatischen aufzeichnung mit patch-clamp |
| EP1530505A4 (de) | 2001-11-30 | 2007-09-12 | Bristol Myers Squibb Co | Pipettenkonfigurationen und arrays dafür zur messung zellularer elektrischer eigenschaften |
| CA2475348A1 (en) * | 2002-02-12 | 2003-08-21 | Cellectricon Ab | Systems and methods for rapidly changing the solution environment around sensors |
| US7470518B2 (en) * | 2002-02-12 | 2008-12-30 | Cellectricon Ab | Systems and method for rapidly changing the solution environment around sensors |
| US7136696B2 (en) | 2002-04-05 | 2006-11-14 | The Cleveland Clinic Foundation | Neuron signal analysis system and method |
| EP1501924A4 (de) | 2002-05-04 | 2006-05-24 | Aviva Biosciences Corp | Vorrichtung mit strukturen nachweisendem ionentransport und verwendungsverfahren |
| IL151315A (en) * | 2002-08-18 | 2010-04-29 | Maroon J Abu Nassar | Fixture for electrode placement |
| WO2004018690A1 (en) * | 2002-08-21 | 2004-03-04 | Cellectricon Ab | System and method for obtaining and maintaining high resistance seals in patch clamp recordings |
| WO2004036202A1 (en) | 2002-10-16 | 2004-04-29 | Cellectricon Ab | Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells |
| US7119645B2 (en) * | 2003-02-25 | 2006-10-10 | The University Of North Carolina | Methods and systems for controlling motion of and tracking a mechanically unattached probe |
| US7015376B2 (en) * | 2004-01-30 | 2006-03-21 | Pioneer Hi-Bred International, Inc. | Soybean variety 95M80 |
| US20050256541A1 (en) * | 2004-04-30 | 2005-11-17 | Medtronic, Inc. | Catheter with temporary stimulation electrode |
| US20050241940A1 (en) * | 2004-05-03 | 2005-11-03 | Wyeth | Fast perfusion system and patch clamp technique utilizing an interface chamber system having high throughput and low volume requirements |
| US7465558B2 (en) * | 2004-05-12 | 2008-12-16 | Wyeth | Perfusion system and apparatus for automated multi-channel patch-clamp recordings utilizing inside-out whole-cell configuration |
| WO2006020187A2 (en) * | 2004-07-16 | 2006-02-23 | The University Of North Carolina At Chapel Hill | Methods, systems and computer program products for full spectrum projection |
| US8095210B2 (en) * | 2007-01-19 | 2012-01-10 | California Institute Of Technology | Prosthetic devices and methods and systems related thereto |
| WO2008103430A2 (en) * | 2007-02-22 | 2008-08-28 | The University Of North Carolina At Chapel Hill | Methods and systems for multiforce high throughput screening |
| DE102008010436A1 (de) * | 2008-02-21 | 2009-09-03 | Berthold Technologies Gmbh & Co. Kg | Vorrichtung und Verfahren zur Messung von Lumineszenz und Fluoreszenz von transfizierten Zellen oder Organteilen |
| ES2673008T3 (es) * | 2008-11-12 | 2018-06-19 | Kerr Scientific Instruments Limited | Aparato para ensayar la actividad eléctrica a partir de una muestra de tejido biológico |
| DE102008058065A1 (de) * | 2008-11-18 | 2010-05-20 | Diasys Diagnostic Systems Gmbh | Automatisierte Analysevorrichtung mit einer automatischen Pipettiervorrichtung und mit einer Messvorrichtung zum Bestimmen der Position der Pipettiernadelspitze |
| WO2010151780A2 (en) | 2009-06-25 | 2010-12-29 | The University Of North Carolina At Chapel Hill | Methods and systems for using actuated surface-attached posts for assessing biofluid rheology |
| BE1018834A3 (nl) * | 2009-07-21 | 2011-09-06 | Praet Peter Van | Inspectie camera gemonteerd op een medische diagnose automaat. |
| EP2302375B1 (de) | 2009-09-29 | 2012-09-12 | Karlsruher Institut für Technologie | Verfahren und Vorrichtung zum Erfassen der Stromspannungskurve einer Zelle |
| EP2710109B1 (de) | 2011-05-19 | 2017-10-25 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen | Verfahren und verwendung einer vorrichtung zur automatisierten positionsbestimmung eines mikrosystems zur manipulation eines sphärischen mikro-objekts |
| CN102866247A (zh) * | 2012-09-26 | 2013-01-09 | 东南大学 | 一种全自动膜片钳电生理纪录系统及记录方法 |
| EP2913391B1 (de) * | 2012-10-25 | 2020-07-01 | Hamamatsu Photonics K.K. | Zellbeobachtungsvorrichtung und zellbeobachtungsverfahren |
| WO2014065330A1 (ja) * | 2012-10-25 | 2014-05-01 | 浜松ホトニクス株式会社 | 細胞観察装置、電気刺激装置、及び細胞観察方法 |
| US9952149B2 (en) | 2012-11-30 | 2018-04-24 | The University Of North Carolina At Chapel Hill | Methods, systems, and computer readable media for determining physical properties of a specimen in a portable point of care diagnostic device |
| US10324080B2 (en) * | 2015-11-17 | 2019-06-18 | Purdue Research Foundation | Systems and methods for automated image-guided patch-clamp electrophysiology in vitro |
| US12085530B2 (en) * | 2015-12-05 | 2024-09-10 | Nano Hesgarsazan Salamat Arya Ncubation Center For Medical Equipment And Devices | Electromechanical approach for cancer detection |
| DK179325B1 (en) | 2016-03-17 | 2018-04-30 | Itu Business Dev A/S | A robot and a method of controlling a robot |
| US10702690B2 (en) | 2017-02-03 | 2020-07-07 | Infinitesimal Llc | Electroporation system with micromanipulator and probe |
| SG11202005265TA (en) | 2017-12-08 | 2020-07-29 | Inventia Life Science Pty Ltd | Bioprinter for fabricating 3d cell constructs |
| EP4231011B1 (de) | 2022-02-16 | 2025-07-09 | Luigs & Neumann Feinmechanik und Elektrotechnik GmbH | Vorrichtungen und verfahren für patch-clamp-messtechnik |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3718066A1 (de) * | 1987-05-29 | 1988-12-08 | Zeiss Carl Fa | Verfahren zur mikroinjektion in zellen bzw. zum absaugen aus einzelnen zellen oder ganzer zellen aus zellkulturen |
| US5108926A (en) * | 1987-09-08 | 1992-04-28 | Board Of Regents, The University Of Texas System | Apparatus for the precise positioning of cells |
| US4932044A (en) * | 1988-11-04 | 1990-06-05 | Yale University | Tissue analyzer |
| US5991028A (en) * | 1991-02-22 | 1999-11-23 | Applied Spectral Imaging Ltd. | Spectral bio-imaging methods for cell classification |
| CA2084099C (en) * | 1991-12-06 | 1996-06-18 | James V. Bacus | Method and apparatus for automated cell analysis |
| US5484731A (en) * | 1993-05-26 | 1996-01-16 | Becton, Dickinson And Company | Multiwell in-vitro fertilization plate |
| EP0788600B1 (de) * | 1994-10-28 | 2002-04-10 | Sophion Bioscience A/S | Patch-clamp-vorrichtung und -technik mit hohem durchfluss und niedrigen flüssigkeitsvolumenanforderungen |
| WO1997017426A1 (en) * | 1995-11-08 | 1997-05-15 | Trustees Of Boston University | Cellular physiology workstations for automated data acquisition and perfusion control |
-
1998
- 1998-04-29 EP EP98919082A patent/EP0980523B1/de not_active Expired - Lifetime
- 1998-04-29 AU AU72054/98A patent/AU729397B2/en not_active Ceased
- 1998-04-29 WO PCT/DK1998/000167 patent/WO1998050791A1/en not_active Ceased
- 1998-04-29 DK DK98919082T patent/DK0980523T3/da active
- 1998-04-29 CA CA002285279A patent/CA2285279A1/en not_active Abandoned
- 1998-04-29 IL IL13182398A patent/IL131823A0/xx unknown
- 1998-04-29 NZ NZ337814A patent/NZ337814A/en unknown
- 1998-04-29 AT AT98919082T patent/ATE349694T1/de not_active IP Right Cessation
- 1998-04-29 DE DE69836736T patent/DE69836736T2/de not_active Expired - Lifetime
- 1998-04-29 JP JP54764298A patent/JP2002507278A/ja active Pending
-
1999
- 1999-09-21 US US09/400,283 patent/US6470226B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69836736D1 (de) | 2007-02-08 |
| NZ337814A (en) | 2001-04-27 |
| WO1998050791A1 (en) | 1998-11-12 |
| IL131823A0 (en) | 2001-03-19 |
| AU729397B2 (en) | 2001-02-01 |
| CA2285279A1 (en) | 1998-11-12 |
| AU7205498A (en) | 1998-11-27 |
| US6470226B1 (en) | 2002-10-22 |
| JP2002507278A (ja) | 2002-03-05 |
| DE69836736T2 (de) | 2007-10-04 |
| DK0980523T3 (da) | 2007-04-30 |
| EP0980523A1 (de) | 2000-02-23 |
| EP0980523B1 (de) | 2006-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |