ATE350021T1 - PHARMACEUTICAL FORMULATION CONTAINING CARRIER BEADS WITH A LAYER OF VALACICLOVIR APPLIED - Google Patents

PHARMACEUTICAL FORMULATION CONTAINING CARRIER BEADS WITH A LAYER OF VALACICLOVIR APPLIED

Info

Publication number
ATE350021T1
ATE350021T1 AT01926063T AT01926063T ATE350021T1 AT E350021 T1 ATE350021 T1 AT E350021T1 AT 01926063 T AT01926063 T AT 01926063T AT 01926063 T AT01926063 T AT 01926063T AT E350021 T1 ATE350021 T1 AT E350021T1
Authority
AT
Austria
Prior art keywords
valaciclovir
pharmaceutical formulation
layer
carrier beads
formulation containing
Prior art date
Application number
AT01926063T
Other languages
German (de)
Inventor
Koho Kawamura
Yasuhiro Mishima
Kiyoshi Ohtsuka
Nobuya Sugibayashi
Keiichi Sugisawa
Hitomi Yanagihara
Makio Yasuda
Original Assignee
Glaxosmithkline Kabushiki Kais
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Kabushiki Kais filed Critical Glaxosmithkline Kabushiki Kais
Application granted granted Critical
Publication of ATE350021T1 publication Critical patent/ATE350021T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A pharmaceutical formulation for valaciclovir comprising carrier beads coated with one or more layers of pharmaceutically acceptable substances, wherein, at least one layer comprises valaciclovir, or a pharmaceutically acceptable derivative thereof, as the active ingredient. There is also provided a process for the preparation of such a formulation.
AT01926063T 2000-04-28 2001-04-27 PHARMACEUTICAL FORMULATION CONTAINING CARRIER BEADS WITH A LAYER OF VALACICLOVIR APPLIED ATE350021T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0010446.3A GB0010446D0 (en) 2000-04-28 2000-04-28 Pharmaceutical formulation

Publications (1)

Publication Number Publication Date
ATE350021T1 true ATE350021T1 (en) 2007-01-15

Family

ID=9890736

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01926063T ATE350021T1 (en) 2000-04-28 2001-04-27 PHARMACEUTICAL FORMULATION CONTAINING CARRIER BEADS WITH A LAYER OF VALACICLOVIR APPLIED

Country Status (11)

Country Link
US (1) US20030108615A1 (en)
EP (1) EP1278515B1 (en)
JP (2) JP4141688B2 (en)
KR (1) KR100803490B1 (en)
AT (1) ATE350021T1 (en)
AU (1) AU781197B2 (en)
CA (1) CA2433897A1 (en)
DE (1) DE60125750T2 (en)
ES (1) ES2280362T3 (en)
GB (1) GB0010446D0 (en)
WO (1) WO2001082905A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040016202A (en) * 2002-08-16 2004-02-21 주식회사 제이알팜 The composition and method for masking bitter taste of hydrocortisone oral preparations
EP2040676A2 (en) * 2006-07-06 2009-04-01 Forest Laboratories, Inc. Orally dissolving formulations of memantine
JP5405752B2 (en) * 2007-01-31 2014-02-05 大日本住友製薬株式会社 Coated drug-containing particles and solid preparation containing the particles
EP2165706A1 (en) 2008-09-18 2010-03-24 BioAlliance Pharma Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers.
EP2335690A1 (en) * 2009-12-09 2011-06-22 BioAlliance Pharma Mucoadhesive buccal tablets for the treatment of orofacial herpes
US8592434B2 (en) 2009-12-09 2013-11-26 Bioalliance Pharma Sa Mucoadhesive buccal tablets for the treatment of orofacial herpes
WO2011070125A1 (en) * 2009-12-09 2011-06-16 Bioalliance Pharma Mucoadhesive buccal tablets for the treatment of orofacial herpes
US20120149720A1 (en) * 2010-07-30 2012-06-14 Ranbaxy Laboratories Limited Valacyclovir formulations
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
HUE050303T2 (en) * 2013-03-13 2020-11-30 Intervet Int Bv Stable bioactive substances and methods of making
EP3416494A4 (en) * 2016-02-17 2019-11-13 Corr-Jensen Inc. VITAMINS AND MINERALS WITH CONTROLLED RELEASE IN EDIBLE OILS
GB201716716D0 (en) * 2017-10-12 2017-11-29 Univ Of Hertfordshire Higher Education Corporation Method for coating particles

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487613A (en) 1892-12-06 Toy wagon
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
US4938966A (en) * 1988-11-30 1990-07-03 Riker Laboratories, Inc. Controlled release flecainide acetate formulation
DE3903217A1 (en) * 1989-02-03 1990-08-09 Boehringer Ingelheim Vetmed PROCESS FOR PRODUCING SOLID PHARMACEUTICAL PREPARATIONS
UA37214C2 (en) * 1991-01-30 2001-05-15 Дзе Веллкам Фаундейшн Лімітед TABLETS DISPERSED IN WATER AND METHOD OF PREPARATION
JPH04283520A (en) * 1991-03-12 1992-10-08 Asahi Chem Ind Co Ltd Spherical nuclei and spherical granule
JP2665858B2 (en) * 1992-05-30 1997-10-22 日本ヘキスト・マリオン・ルセル株式会社 Long-acting oxybutynin hydrochloride preparation
JPH0826977A (en) * 1994-07-19 1996-01-30 Tanabe Seiyaku Co Ltd Controlled dissolution oral formulation
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
JPH0971524A (en) * 1995-09-08 1997-03-18 Fujisawa Pharmaceut Co Ltd Sustained release granule and method for producing the same
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
CA2243237C (en) * 1996-01-19 2008-09-02 Glaxo Group Limited Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application
US6248636B1 (en) * 1998-05-28 2001-06-19 Samsung Electronics Co., Ltd. Method for forming contact holes of semiconductor memory device
JP3466921B2 (en) * 1998-06-03 2003-11-17 大塚製薬株式会社 Taste masking pharmaceutical formulation
JP2000103732A (en) * 1998-07-28 2000-04-11 Tanabe Seiyaku Co Ltd Intestinal release-in-place preparation
JP2000053563A (en) * 1998-08-07 2000-02-22 Bayer Yakuhin Ltd Quick-release fine granules with masked bitterness
WO2000009133A1 (en) * 1998-08-10 2000-02-24 Asahi Kasei Kogyo Kabushiki Kaisha Sustained release oral preparations of fasudil hydrochloride
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Also Published As

Publication number Publication date
KR100803490B1 (en) 2008-02-14
CA2433897A1 (en) 2001-11-08
KR20030011834A (en) 2003-02-11
JP2006290903A (en) 2006-10-26
AU781197B2 (en) 2005-05-12
US20030108615A1 (en) 2003-06-12
JP2003531851A (en) 2003-10-28
JP4141688B2 (en) 2008-08-27
AU5265801A (en) 2001-11-12
DE60125750D1 (en) 2007-02-15
ES2280362T3 (en) 2007-09-16
WO2001082905A1 (en) 2001-11-08
EP1278515B1 (en) 2007-01-03
GB0010446D0 (en) 2000-06-14
EP1278515A1 (en) 2003-01-29
DE60125750T2 (en) 2007-10-31

Similar Documents

Publication Publication Date Title
EP1356808A3 (en) Coating technique for deposition of drug substance on a substrate
NO975131D0 (en) Powder coating composition for electrostatic coating of pharmaceutical substrates
CA2398555A1 (en) Sustained release preparation and method for producing the same
HUP0201788A2 (en) Multilayered film containing an active substance and made of cross-linked hydrophilic polymers
JP2002511411A5 (en)
DE60125750D1 (en) PHARMACEUTICAL FORMULATION CONTAINING SUPPORT BEADS WITH LAYERED VALACICLOVIR LAYER
UY26372A1 (en) "IMIDAZO-3-IL-AMINAS BICÍCLICAS PROCEDURE FOR ITS PREPARATION AND DRUGS THAT CONTAIN THEM"
WO2002072033A3 (en) Chronotherapeutic dosage forms containing glucocorticosteroid
DE69909316D1 (en) PHARMACEUTICAL FORMULATION WITH OMEPRAZOL
AU2002226674A1 (en) Tricyclic and heterocyclic derivative compounds and drugs containing these compounds as the active ingredient
CA2490820A1 (en) Articles, systems and methods for dispensing volatile materials into the environment
IT1264517B1 (en) PHARMACEUTICAL TABLET SUITABLE FOR THE RELEASE IN SUBSEQUENT TIMES OF THE ACTIVE PRINCIPLES CARRIED THEREIN
PT1231918E (en) NEW COMPOSITION AND USE
NO20034149L (en) Medicines containing triazaspiro [5.5] undecane derivatives as the active ingredient
AU2002219174A1 (en) Quinazoline derivatives, medicaments containing said compounds, their utilization and method for the production thereof
AU2002238855A1 (en) N-phenylarylsulfonamide compound, drug containing the compound as active ingredient, intermediate for the compound, and processes for producing the same
DE59907481D1 (en) CONTROLLING RELEASING PHARMACEUTICAL COMPOSITION WITH TILIDINE MESYLATE AS AN ACTIVE SUBSTANCE
ATE304013T1 (en) 1,2,3-SUBSTITUTED INDOLIZINE DERIVATIVES, FGF INHIBITORS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME
AU2001288114A1 (en) Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient
AU2001234107A1 (en) Benzoic acid derivatives, process for producing the same and drugs containing the same as the active ingredient
EA199800593A1 (en) MICROGRAWNS WITH PROLONGED SURVENT, CONTAINING DILTIAZE AS AN ACTIVE INGREDIENT
ATE341312T1 (en) ORAL DELAYED RELEASE PHARMACEUTICAL COMPOSITION
DE69706070D1 (en) PREPARATION FOR PERCUTANEOUS ADMINISTRATION CONTAINING 6-AMINO-5-CHLORO-1-ISOPROPYL-2- (4-METHYL-1-PIPERAZINYL) BENZIMIDAZOLE
DK0599064T3 (en) Retard form for pharmaceutically active agents
ES2060293T3 (en) NEW ANTI-ULCER SUBSTANCE.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties