ATE350040T1 - Stabilisierte pharmazeutische zusammensetzung enthaltend einen nichtsteroiden entzündungshemmenden wirkstoff und prostaglandin - Google Patents
Stabilisierte pharmazeutische zusammensetzung enthaltend einen nichtsteroiden entzündungshemmenden wirkstoff und prostaglandinInfo
- Publication number
- ATE350040T1 ATE350040T1 AT00910474T AT00910474T ATE350040T1 AT E350040 T1 ATE350040 T1 AT E350040T1 AT 00910474 T AT00910474 T AT 00910474T AT 00910474 T AT00910474 T AT 00910474T AT E350040 T1 ATE350040 T1 AT E350040T1
- Authority
- AT
- Austria
- Prior art keywords
- prostaglandin
- pharmaceutical composition
- nsaid
- composition containing
- composition
- Prior art date
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 3
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229960001259 diclofenac Drugs 0.000 abstract 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- OJLOPKGSLYJEMD-URPKTTJQSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(1e)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC OJLOPKGSLYJEMD-URPKTTJQSA-N 0.000 abstract 1
- 229960005249 misoprostol Drugs 0.000 abstract 1
- 229960002702 piroxicam Drugs 0.000 abstract 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007909 solid dosage form Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/273,692 US6183779B1 (en) | 1999-03-22 | 1999-03-22 | Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE350040T1 true ATE350040T1 (de) | 2007-01-15 |
Family
ID=23045012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00910474T ATE350040T1 (de) | 1999-03-22 | 2000-03-20 | Stabilisierte pharmazeutische zusammensetzung enthaltend einen nichtsteroiden entzündungshemmenden wirkstoff und prostaglandin |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6183779B1 (de) |
| EP (1) | EP1162975B1 (de) |
| AT (1) | ATE350040T1 (de) |
| AU (1) | AU3269200A (de) |
| CA (1) | CA2301378C (de) |
| DE (1) | DE60032749T2 (de) |
| WO (1) | WO2000056339A1 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8022095B2 (en) | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
| US6319519B2 (en) | 1998-07-07 | 2001-11-20 | Norton Healthcare Ltd. | Anti-inflammatory pharmaceutical formulations |
| US6514525B2 (en) | 1998-09-10 | 2003-02-04 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| US6387410B1 (en) * | 1998-09-10 | 2002-05-14 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| JP2003510347A (ja) * | 1999-10-01 | 2003-03-18 | ノートン ヘルスケアー リミテッド | 抗炎症医薬品製剤 |
| KR20030019326A (ko) * | 2000-03-21 | 2003-03-06 | 니뽄 신야쿠 가부시키가이샤 | 방출 제어형 경구 투여 제제 |
| AR030557A1 (es) * | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
| US20020035107A1 (en) * | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
| US20020192299A1 (en) * | 2000-12-28 | 2002-12-19 | Rajneesh Taneja | Pharmaceutical compositions of a non-enteric coated proton pump inhibitor with a carbonate salt and bicarbonate salt combination |
| US20020177626A1 (en) | 2001-01-19 | 2002-11-28 | Cook Graham D. | Treatment of sleep disturbances |
| US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
| GB2380937A (en) * | 2001-10-18 | 2003-04-23 | David Ian Slovick | Method of dispensing a plurality of medical substances into capsules |
| DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
| RU2196570C1 (ru) * | 2001-12-13 | 2003-01-20 | ЗАО "Медисорб" | Фармацевтическая композиция, обладающая противовоспалительной активностью |
| GB2386817B (en) * | 2002-02-20 | 2006-08-23 | Walcom Animal Science | Feed for fish and use therof |
| US8323692B2 (en) | 2002-02-21 | 2012-12-04 | Valeant International Bermuda | Controlled release dosage forms |
| AU2003211146B2 (en) * | 2002-02-21 | 2007-07-19 | Valeant International (Barbados) Srl | Controlled release dosage forms |
| US20050124699A1 (en) * | 2002-07-02 | 2005-06-09 | Wakamoto Pharmaceutical Co., Ltd. | Drugs for treating or preventing disorders of corneal and/or conjunctival epithelial cells |
| US20040082618A1 (en) * | 2002-07-03 | 2004-04-29 | Rajneesh Taneja | Liquid dosage forms of acid labile drugs |
| US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
| US20070243251A1 (en) * | 2002-12-20 | 2007-10-18 | Rajneesh Taneja | Dosage Forms Containing A PPI, NSAID, and Buffer |
| US20040121004A1 (en) * | 2002-12-20 | 2004-06-24 | Rajneesh Taneja | Dosage forms containing a PPI, NSAID, and buffer |
| CA2554012A1 (en) * | 2003-01-21 | 2004-08-05 | Smartrix Technologies Inc. | Oral dosage formulation |
| EP1462098B1 (de) * | 2003-03-03 | 2007-07-04 | SPRL Franpharma | Stabilisierte pharmazeutische Zusammensetzung enthaltend einen NSAID und einen Prostaglandin |
| WO2004091579A1 (en) * | 2003-04-16 | 2004-10-28 | Pharmacia Corporation | Stabilized prostaglandin formulation |
| US20050096311A1 (en) * | 2003-10-30 | 2005-05-05 | Cns Response | Compositions and methods for treatment of nervous system disorders |
| EP1568369A1 (de) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam zur Behandlung von Atemwegserkrankungen bei Schweinen |
| DE102004021281A1 (de) * | 2004-04-29 | 2005-11-24 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin |
| DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
| WO2006070406A1 (en) * | 2004-12-29 | 2006-07-06 | J.B. Chemicals & Pharmaceuticals Ltd | Bilayer tablets of oxcarbazepine for controlled delivery and a process of preparation thereof |
| US20060177504A1 (en) * | 2005-02-08 | 2006-08-10 | Renjit Sundharadas | Combination pain medication |
| US20070053868A1 (en) * | 2005-03-08 | 2007-03-08 | Banner Pharmacaps, Inc. | Solvent system for enhancing the solubility of pharmaceutical agents |
| WO2006099618A1 (en) * | 2005-03-16 | 2006-09-21 | Dr. Reddy's Laboratories Ltd. | Delivery system for multiple drugs |
| US20070224259A1 (en) * | 2005-09-21 | 2007-09-27 | Gupta Anil K | Anti-inflammatory pharmaceutical composition |
| SG166115A1 (en) * | 2005-09-30 | 2010-11-29 | Boehringer Ingelheim Vetmed | Pharmaceutical preparation containing meloxicam |
| US20090304786A1 (en) * | 2005-11-25 | 2009-12-10 | Viswaprasad Varanasi | Stable Dosage Forms of an Antidepressant |
| RU2403013C2 (ru) * | 2005-12-16 | 2010-11-10 | Ханми Фарм. Ко., Лтд. | Твердая дисперсия, содержащая активный ингредиент с низкой температурой плавления, и содержащая ее таблетка для перорального введения |
| EP1988886A1 (de) * | 2006-02-13 | 2008-11-12 | Intelgenx Corporation | Pharmazeutische orale dosierform mit verzögerter freisetzung und herstellungsverfahren dafür |
| US8653066B2 (en) | 2006-10-09 | 2014-02-18 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
| US8574625B2 (en) | 2007-05-30 | 2013-11-05 | Wockhardt Ltd. | Tablet dosage form |
| US20090012165A1 (en) * | 2007-07-03 | 2009-01-08 | Sucampo Ag | Pharmaceutical combination of nsaid and prostaglandin compound |
| EP2240022B1 (de) | 2008-01-09 | 2016-12-28 | Charleston Laboratories, Inc. | Oxycodone und Promethazine enthaltende zweischichtige Tabletten |
| US20090214648A1 (en) * | 2008-02-15 | 2009-08-27 | Malathi Kandakatla | Pharmaceutical formulations comprising ibuprofen and diphenhydramine |
| US8569375B2 (en) * | 2008-08-22 | 2013-10-29 | Reckitt Benckiser Healthcare (Uk) Limited | Compositions |
| KR20110079641A (ko) | 2008-09-09 | 2011-07-07 | 아스트라제네카 아베 | 제약 조성물을 이를 필요로 하는 환자에게 전달하는 방법 |
| US20100233259A1 (en) * | 2008-12-12 | 2010-09-16 | Pascal Grenier | Dosage form of ropinirole |
| MX2011013467A (es) | 2009-06-25 | 2012-02-13 | Astrazeneca Ab | Metodo para tratar un paciente que corre el riesgo de desarollar una ulcera asociada a antiinflamatorio no esteroide (aine). |
| NZ597534A (en) * | 2009-06-25 | 2013-09-27 | Pozen Inc | Method for treating a patient in need of aspirin therapy |
| EP2451274B1 (de) | 2009-07-08 | 2017-10-04 | Charleston Laboratories, Inc. | Pharmazeutische zusammensetzungen |
| US9101529B2 (en) | 2009-10-12 | 2015-08-11 | Boehringer Ingelheim Vetmedica Gmbh | Containers for compositions comprising meloxicam |
| WO2011107150A1 (en) | 2010-03-03 | 2011-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| CN102336693B (zh) * | 2010-07-21 | 2014-01-22 | 上海天伟生物制药有限公司 | 卡前列素氨丁三醇的晶体及其制备方法和用途 |
| EP2765999A4 (de) * | 2011-10-14 | 2015-04-01 | Purdue Research Foundation | Einnehmbare mehrschichtige einheit mit vorgegebenen funktionen und kombinationen |
| US9539214B2 (en) | 2011-12-28 | 2017-01-10 | Pozen Inc. | Compositions and methods for delivery of omeprazole plus acetylsalicylic acid |
| CN105435239B (zh) * | 2014-08-29 | 2019-04-26 | 武汉光谷人福生物医药有限公司 | 美索舒利薄膜衣片及其制备方法 |
| US9839212B2 (en) | 2015-04-16 | 2017-12-12 | Bio-Lab, Inc. | Multicomponent and multilayer compacted tablets |
| US10179109B2 (en) | 2016-03-04 | 2019-01-15 | Charleston Laboratories, Inc. | Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates |
| CN115040491A (zh) * | 2021-03-09 | 2022-09-13 | 上海天慈生物谷生物工程有限公司 | 钾离子竞争性酸阻滞剂和乙酰水杨酸的复方制剂及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3781429A (en) | 1972-09-29 | 1973-12-25 | American Cyanamid Co | Method of inhibiting ulcerogenesis induced by non-steroidal anti-inflammatory agents |
| US3927213A (en) | 1973-07-10 | 1975-12-16 | American Home Prod | Prostaglandin E{HD 2 {B and derivatives for reducing the side effects of anti-inflammatory agents |
| US3928588A (en) | 1974-02-22 | 1975-12-23 | Upjohn Co | Method of reducing the undesirable gastrointestinal effects of prostaglandin synthetase inhibitors |
| US3954787A (en) | 1974-06-18 | 1976-05-04 | Pfizer Inc. | Stabilized E-series prostaglandins |
| US4301146A (en) | 1980-07-29 | 1981-11-17 | G. D. Searle & Co. | Stabilization of 16-oxygenated prostanoic acid derivatives |
| US5015481A (en) | 1990-05-03 | 1991-05-14 | G. D. Searle & Co. | Stabilized pharmaceutical admixture composition |
| WO1991016895A1 (en) | 1990-05-03 | 1991-11-14 | G.D. Searle & Co. | Pharmaceutical composition |
| AU9062998A (en) | 1997-09-11 | 1999-03-29 | Nycomed Danmark A/S | Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (nsaids) |
| CA2241342C (en) | 1998-06-15 | 2000-02-08 | Bernard Charles Sherman | Pharmaceutical tablets comprising an nsaid and a prostaglandin |
| GB9814215D0 (en) | 1998-07-01 | 1998-09-02 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| GB9819685D0 (en) | 1998-09-10 | 1998-11-04 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
-
1999
- 1999-03-22 US US09/273,692 patent/US6183779B1/en not_active Expired - Lifetime
-
2000
- 2000-03-20 DE DE60032749T patent/DE60032749T2/de not_active Expired - Lifetime
- 2000-03-20 WO PCT/CA2000/000301 patent/WO2000056339A1/en not_active Ceased
- 2000-03-20 AU AU32692/00A patent/AU3269200A/en not_active Abandoned
- 2000-03-20 US US09/528,550 patent/US6287600B1/en not_active Expired - Fee Related
- 2000-03-20 AT AT00910474T patent/ATE350040T1/de not_active IP Right Cessation
- 2000-03-20 CA CA002301378A patent/CA2301378C/en not_active Expired - Fee Related
- 2000-03-20 EP EP00910474A patent/EP1162975B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2301378C (en) | 2005-07-26 |
| EP1162975B1 (de) | 2007-01-03 |
| WO2000056339A1 (en) | 2000-09-28 |
| CA2301378A1 (en) | 2000-09-22 |
| DE60032749T2 (de) | 2007-10-18 |
| AU3269200A (en) | 2000-10-09 |
| EP1162975A1 (de) | 2001-12-19 |
| US6287600B1 (en) | 2001-09-11 |
| DE60032749D1 (de) | 2007-02-15 |
| US6183779B1 (en) | 2001-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |