ATE350474T1 - Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird - Google Patents

Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird

Info

Publication number
ATE350474T1
ATE350474T1 AT99942113T AT99942113T ATE350474T1 AT E350474 T1 ATE350474 T1 AT E350474T1 AT 99942113 T AT99942113 T AT 99942113T AT 99942113 T AT99942113 T AT 99942113T AT E350474 T1 ATE350474 T1 AT E350474T1
Authority
AT
Austria
Prior art keywords
bpc
secreted
cancer cells
expressed
bladder cancer
Prior art date
Application number
AT99942113T
Other languages
English (en)
Inventor
Daniel E Afar
Rene S Hubert
Kahan Leong
Arthur B Raitano
Douglas C Saffran
Aya Jakobovits
Original Assignee
Agensys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agensys Inc filed Critical Agensys Inc
Application granted granted Critical
Publication of ATE350474T1 publication Critical patent/ATE350474T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT99942113T 1998-08-10 1999-08-10 Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird ATE350474T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9598298P 1998-08-10 1998-08-10

Publications (1)

Publication Number Publication Date
ATE350474T1 true ATE350474T1 (de) 2007-01-15

Family

ID=22254489

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99942113T ATE350474T1 (de) 1998-08-10 1999-08-10 Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird

Country Status (9)

Country Link
US (4) US6277972B1 (de)
EP (1) EP1104462B1 (de)
JP (2) JP4282906B2 (de)
AT (1) ATE350474T1 (de)
AU (1) AU756452B2 (de)
CA (1) CA2338982C (de)
DE (1) DE69934694T2 (de)
IL (2) IL141061A0 (de)
WO (1) WO2000009691A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276488B2 (en) * 1997-06-04 2007-10-02 Oxford Biomedica (Uk) Limited Vector system
US7635687B2 (en) * 1997-06-04 2009-12-22 Oxford Biomedica (Uk) Limited Vector system
US6852703B1 (en) * 1997-06-04 2005-02-08 Oxford Biomedica (Uk) Limited Tumor targeted vector
US8096872B2 (en) * 1998-06-22 2012-01-17 Igt Method and apparatus for providing electronic credits at a gaming device without first requiring payment therefor
DE69934694T2 (de) * 1998-08-10 2007-10-04 Agensys, Inc., Santa Monica Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird
WO2000071711A2 (en) * 1999-05-20 2000-11-30 Fahri Saatcioglu Differentially expressed genes in prostate cancer
US7189565B2 (en) * 2001-03-23 2007-03-13 Fahri Saatcioglu Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US7611892B2 (en) * 2000-03-24 2009-11-03 President And Fellows Of Harvard College Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
EP1301533A1 (de) * 2000-07-07 2003-04-16 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Tumorassoziiertes antigen (b345), gekennzeichnet durch eine aminosäuresequenz wie in seq. id. no. 4
US7390263B1 (en) * 2000-10-19 2008-06-24 Igt Method of implementing cashless play of gaming devices interconnected by a computer network
GB0126378D0 (en) * 2001-11-02 2002-01-02 Oxford Biomedica Ltd Antigen
AU2003208871A1 (en) * 2002-02-18 2003-09-04 Lynkeus Bio Tech Gmbh Novel retina specific human proteins wdr17, net01, protein kinase a203, protein kinase mak a194, protein a105, protein a106 and c12orf3variants
US20040018580A1 (en) * 2002-05-10 2004-01-29 Chai Karl X. Synthetic substrates for prostasin
CA2514058C (en) * 2003-01-24 2014-05-13 Agensys, Inc. Nucleic acids and corresponding proteins entitled 254p1d6b useful in treatment and detection of cancer
DE602004032107D1 (de) * 2003-02-07 2011-05-19 Univ California Nell-peptidexpressionssysteme und knochenbildende aktivität des nell-peptids
WO2005027845A2 (en) * 2003-09-18 2005-03-31 Alexion Pharmaceuticals, Inc. Method of identifying cell surface molecules involved in cancer metastasis
CA2631184A1 (en) 2005-11-28 2007-05-31 Genmab A/S Recombinant monovalent antibodies and methods for production thereof
US8142280B2 (en) * 2006-07-25 2012-03-27 Igt Method and apparatus for conditional payouts in a gaming device
EP2156184B1 (de) * 2007-05-08 2013-11-27 Picobella, LLC Verfahren zur diagnostizierung und behandlung von prostata- und lungenkrebs
JP2009245920A (ja) * 2008-03-11 2009-10-22 Sony Corp 燃料電池、電子機器および燃料電池用緩衝液

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002480D0 (sv) * 1990-07-23 1990-07-23 Hans Lilja Assay of free and complexed prostate-specific antigen
ATE302789T1 (de) * 1993-02-09 2005-09-15 Univ Johns Hopkins Med Zellkernmatrixproteine
EP0904397A4 (de) * 1996-04-16 2003-01-29 Smithkline Beecham Corp Methode zur erkennung des prostat-spezifischen antigens zur überwachung und diagnose von prostatkrebs
DE69934694T2 (de) * 1998-08-10 2007-10-04 Agensys, Inc., Santa Monica Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird
CA2296792A1 (en) 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
US20020164705A1 (en) 2001-01-08 2002-11-07 Rajasekhar Bandaru 39362, a novel human CUB domain-containing protein family member and uses thereof
CA2446437A1 (en) 2001-05-03 2002-11-14 Curagen Corporation Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
US20040248251A1 (en) 2001-07-17 2004-12-09 Lal Preeti G Receptors and membrane associated proteins

Also Published As

Publication number Publication date
IL141061A (en) 2009-12-24
US20050148012A1 (en) 2005-07-07
EP1104462A2 (de) 2001-06-06
EP1104462B1 (de) 2007-01-03
JP4637055B2 (ja) 2011-02-23
US20020161212A1 (en) 2002-10-31
US6277972B1 (en) 2001-08-21
JP2006320324A (ja) 2006-11-30
US7785811B2 (en) 2010-08-31
AU756452B2 (en) 2003-01-16
DE69934694D1 (de) 2007-02-15
JP2002522076A (ja) 2002-07-23
CA2338982A1 (en) 2000-02-24
WO2000009691A3 (en) 2000-05-11
CA2338982C (en) 2011-03-15
WO2000009691A2 (en) 2000-02-24
US20100168027A1 (en) 2010-07-01
US8003758B2 (en) 2011-08-23
IL141061A0 (en) 2002-02-10
WO2000009691A9 (en) 2000-08-03
JP4282906B2 (ja) 2009-06-24
AU5556199A (en) 2000-03-06
DE69934694T2 (de) 2007-10-04

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