ATE352357T1 - Chromatographisches sorptionsmittel aus mineraloxidperlen deren poren hydroxylapatit enthalten - Google Patents

Chromatographisches sorptionsmittel aus mineraloxidperlen deren poren hydroxylapatit enthalten

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Publication number
ATE352357T1
ATE352357T1 AT02258148T AT02258148T ATE352357T1 AT E352357 T1 ATE352357 T1 AT E352357T1 AT 02258148 T AT02258148 T AT 02258148T AT 02258148 T AT02258148 T AT 02258148T AT E352357 T1 ATE352357 T1 AT E352357T1
Authority
AT
Austria
Prior art keywords
mineral oxide
sorpent
chromatographic
oxide beads
whose pores
Prior art date
Application number
AT02258148T
Other languages
English (en)
Inventor
Egisto Boschetti
Pierre Girot
Original Assignee
Pall Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pall Corp filed Critical Pall Corp
Application granted granted Critical
Publication of ATE352357T1 publication Critical patent/ATE352357T1/de

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/0203—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of metals not provided for in B01J20/04
    • B01J20/0211—Compounds of Ti, Zr, Hf
    • B—PERFORMING OPERATIONS; TRANSPORTING
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
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  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
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AT02258148T 2001-11-27 2002-11-27 Chromatographisches sorptionsmittel aus mineraloxidperlen deren poren hydroxylapatit enthalten ATE352357T1 (de)

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US33314901P 2001-11-27 2001-11-27

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ATE352357T1 true ATE352357T1 (de) 2007-02-15

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Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2834227A1 (fr) * 2001-12-27 2003-07-04 Chiralsep Sarl Materiaux supports optiquement actifs, leur procede de preparation et leurs utilisations
US8287914B2 (en) * 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
US7468973B2 (en) * 2006-07-07 2008-12-23 Alcatel-Lucent Usa Inc. Switch data transform to IMS process
KR100828096B1 (ko) 2006-12-28 2008-05-08 금오공과대학교 산학협력단 하이드록시아파타이트 및 폴리아크릴아미드 복합 겔의제조방법
RU2405623C1 (ru) * 2009-07-27 2010-12-10 Учреждение Российской академии наук Институт биологии Коми научного центра Уральского отделения РАН Способ получения адсорбента для препаративной хроматографии белков
IT1395280B1 (it) 2009-08-12 2012-09-05 London Equitable Ltd In Its Capacity As Trustee Of The Think Tank Trust Gruppo di catetere ad espansione e relativo corredo o kit
JP5724050B2 (ja) 2009-09-28 2015-05-27 Hoya株式会社 粉体、粉体の製造方法、吸着装置
JP5636685B2 (ja) * 2010-02-02 2014-12-10 独立行政法人水産総合研究センター ノロウイルス検出用材料および該材料を用いるノロウイルスの検出方法
US9815695B2 (en) 2012-05-30 2017-11-14 Bio-Rad Laboratories, Inc. In situ restoration of apatite-based chromatography resins
MY178616A (en) 2012-09-17 2020-10-19 Grace W R & Co Chromatography media and devices
JP6914189B2 (ja) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 官能化担体材料並びに官能化担体材料を作製及び使用する方法
CN105392569B (zh) * 2014-06-23 2019-08-20 生物辐射实验室股份有限公司 磷灰石预处理
WO2016040106A1 (en) * 2014-09-08 2016-03-17 The Board Of Trustees Of The University Of Illinois Refractive index-based detection for liquid chromatography using a microring resonator array
CN107921407B (zh) 2015-06-05 2022-07-05 格雷斯公司 生物处理吸附澄清剂及其制备和使用方法
JP6588765B2 (ja) * 2015-08-07 2019-10-09 学校法人 神野学園 Ｄｎａ吸着担体及びその利用方法
JP6710823B2 (ja) * 2015-09-01 2020-06-17 国立研究開発法人産業技術総合研究所 タンパク質固定化用担体及びその製造方法
EP4574227A3 (de) 2016-09-29 2025-09-03 Bio-Rad Laboratories, Inc. Reinigungsverfahren für protein-nanopartikel-konjugat
US10814305B2 (en) 2016-09-29 2020-10-27 Bio-Rad Laboratories, Inc. Agarose-filled ceramic apatite
WO2020128021A1 (en) * 2018-12-20 2020-06-25 Solvay Sa Particles comprising hydroxyapatite, process for making and their use
JP7577538B2 (ja) 2020-02-19 2024-11-05 バイオ－ラッド ラボラトリーズ インコーポレーティッド ポリマー充填クロマトグラフィー樹脂を調製する方法
CN115477535A (zh) * 2022-09-09 2022-12-16 晞华生物科技(上海)有限公司 一种层析用陶瓷羟基磷灰石及其制备方法、用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5441635A (en) * 1986-07-05 1995-08-15 Asahi Kogaku Kogyo Kabushiki Kaisha Packing material for liquid chromatography
US3954678A (en) * 1974-07-11 1976-05-04 E. I. Du Pont De Nemours And Company Semipermeable microcapsules containing a silica gel
JPH0762674B2 (ja) 1986-03-07 1995-07-05 株式会社高研 クロマトグラフイ−用吸着剤、及びその製造方法、並びに該吸着剤を使用したクロマトグラフイ−カラム
JP2573825B2 (ja) 1986-03-31 1997-01-22 東燃株式会社 水酸アパタイト粒子集合体、その製造方法及びそのクロマトグラフイ−充填剤としての用途
CA1329800C (en) * 1987-12-29 1994-05-24 Hiroaki Takayanagi Composite separating agent
US5240601A (en) * 1988-11-09 1993-08-31 Chembiomed, Ltd. Affinity supports for hemoperfusion
EP0673667B1 (de) * 1989-04-21 2000-09-20 Asahi Kogaku Kogyo Kabushiki Kaisha Filterschicht
JPH0832551B2 (ja) * 1989-06-24 1996-03-29 旭光学工業株式会社 多孔質リン酸カルシウム系化合物粒子及びその製造方法
BE1007489A3 (nl) * 1993-09-10 1995-07-11 Philips Electronics Nv Zuighulpstuk, alsmede sproeiorgaan geschikt voor toepassing in een dergelijk zuighulpstuk en stofzuiger voorzien van een dergelijk zuighulpstuk.
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
SE9700769D0 (sv) * 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
US6613234B2 (en) * 1998-04-06 2003-09-02 Ciphergen Biosystems, Inc. Large pore volume composite mineral oxide beads, their preparation and their applications for adsorption and chromatography

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JP2005512070A (ja) 2005-04-28
DE60217800T2 (de) 2007-11-15
US20060021941A1 (en) 2006-02-02
EP1314467B1 (de) 2007-01-24
EP1314467A1 (de) 2003-05-28
DE60217800D1 (de) 2007-03-15
WO2003049833A1 (en) 2003-06-19
AU2002350258A1 (en) 2003-06-23
US20030125529A1 (en) 2003-07-03
US6972090B2 (en) 2005-12-06

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