ATE354371T1 - Adjuvantien und verfahren zur induktion einer th2 immunantwort - Google Patents

Adjuvantien und verfahren zur induktion einer th2 immunantwort

Info

Publication number: ATE354371T1
Authority: AT; Austria
Prior art keywords: immune response; gingivalis; detoxified; derivatives; lps
Prior art date: 2000-06-16

Application number

AT01944590T

Other languages

English (en)

Inventor

Bali Pulendran

Jacques F Banchereau

Christopher W Cutler

Original Assignee

Baylor Res Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-16

Filing date

2001-06-18

Publication date

2007-03-15

2001-06-18 Application filed by Baylor Res Inst filed Critical Baylor Res Inst

2007-03-15 Application granted granted Critical

2007-03-15 Publication of ATE354371T1 publication Critical patent/ATE354371T1/de

Links

230000029069 type 2 immune response Effects 0.000 title abstract 5
239000002671 adjuvant Substances 0.000 title abstract 2
230000001939 inductive effect Effects 0.000 title 1
241000605862 Porphyromonas gingivalis Species 0.000 abstract 8
GZQKNULLWNGMCW-PWQABINMSA-N lipid A (E. coli) Chemical compound O1[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H]1OC[C@@H]1[C@@H](O)[C@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OP(O)(O)=O)O1 GZQKNULLWNGMCW-PWQABINMSA-N 0.000 abstract 4
241001465754 Metazoa Species 0.000 abstract 2
208000035473 Communicable disease Diseases 0.000 abstract 1
230000029662 T-helper 1 type immune response Effects 0.000 abstract 1
238000010171 animal model Methods 0.000 abstract 1
230000006472 autoimmune response Effects 0.000 abstract 1
238000009776 industrial production Methods 0.000 abstract 1
238000002255 vaccination Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/739—Lipopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Mycology (AREA)
Microbiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT01944590T 2000-06-16 2001-06-18 Adjuvantien und verfahren zur induktion einer th2 immunantwort ATE354371T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US21218200P	2000-06-16	2000-06-16

Publications (1)

Publication Number	Publication Date
ATE354371T1 true ATE354371T1 (de)	2007-03-15

Family

ID=22789909

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01944590T ATE354371T1 (de)	2000-06-16	2001-06-18	Adjuvantien und verfahren zur induktion einer th2 immunantwort

Country Status (6)

Country	Link
US (1)	US6818221B2 (de)
EP (1)	EP1292332B1 (de)
AT (1)	ATE354371T1 (de)
AU (1)	AU2001266983A1 (de)
DE (1)	DE60126768T2 (de)
WO (1)	WO2001097838A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004074435A2 (en) *	2003-01-30	2004-09-02	Emory University	Methods for identifying and administering agents that bias the immune response via dendritic cells
JP2007504145A (ja) *	2003-08-25	2007-03-01	スリーエムイノベイティブプロパティズカンパニー	免疫刺激性の組み合わせおよび治療
US7622128B2 (en) *	2005-12-13	2009-11-24	University Of Washington	Porphyromonas gingivalis 1435/1449 LPS as an immune modulator

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2249994A1 (en) *	1996-03-22	1997-09-25	University Of Georgia Research Foundation, Inc.	Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
AUPN901296A0 (en) *	1996-03-29	1996-04-26	University Of Melbourne, The	Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis

2001
- 2001-06-18 DE DE60126768T patent/DE60126768T2/de not_active Expired - Lifetime
- 2001-06-18 EP EP01944590A patent/EP1292332B1/de not_active Expired - Lifetime
- 2001-06-18 AT AT01944590T patent/ATE354371T1/de not_active IP Right Cessation
- 2001-06-18 WO PCT/US2001/019411 patent/WO2001097838A2/en not_active Ceased
- 2001-06-18 US US10/311,123 patent/US6818221B2/en not_active Expired - Fee Related
- 2001-06-18 AU AU2001266983A patent/AU2001266983A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE60126768T2 (de)	2007-10-25
DE60126768D1 (de)	2007-04-05
EP1292332A2 (de)	2003-03-19
AU2001266983A1 (en)	2002-01-02
WO2001097838A2 (en)	2001-12-27
WO2001097838A3 (en)	2002-06-27
US6818221B2 (en)	2004-11-16
EP1292332B1 (de)	2007-02-21
US20040082538A1 (en)	2004-04-29

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Legal Events

Date	Code	Title	Description
2007-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties