ATE354640T1 - Herstellung von geschichteten und nach zelltyp geordneten geweben in vitro - Google Patents

Herstellung von geschichteten und nach zelltyp geordneten geweben in vitro

Info

Publication number
ATE354640T1
ATE354640T1 AT01991014T AT01991014T ATE354640T1 AT E354640 T1 ATE354640 T1 AT E354640T1 AT 01991014 T AT01991014 T AT 01991014T AT 01991014 T AT01991014 T AT 01991014T AT E354640 T1 ATE354640 T1 AT E354640T1
Authority
AT
Austria
Prior art keywords
tissue
vitro
cell
cell type
ordered
Prior art date
Application number
AT01991014T
Other languages
English (en)
Inventor
Warren K Hoeffler
Deborah Finlay
Original Assignee
Xgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xgene Corp filed Critical Xgene Corp
Application granted granted Critical
Publication of ATE354640T1 publication Critical patent/ATE354640T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/30—Coculture with; Conditioned medium produced by tumour cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/04—Screening or testing on artificial tissues
    • C12N2503/06—Screening or testing on artificial skin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT01991014T 2000-12-08 2001-12-07 Herstellung von geschichteten und nach zelltyp geordneten geweben in vitro ATE354640T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25478100P 2000-12-08 2000-12-08

Publications (1)

Publication Number Publication Date
ATE354640T1 true ATE354640T1 (de) 2007-03-15

Family

ID=22965565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01991014T ATE354640T1 (de) 2000-12-08 2001-12-07 Herstellung von geschichteten und nach zelltyp geordneten geweben in vitro

Country Status (6)

Country Link
US (2) US6815202B2 (de)
EP (1) EP1339831B1 (de)
AT (1) ATE354640T1 (de)
AU (1) AU2002230768A1 (de)
DE (1) DE60126815T2 (de)
WO (1) WO2002046375A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY137139A (en) * 2004-06-29 2008-12-31 Univ Kebangsaan Malaysia Formation of tissue engineered human skin using hpd as biomaterials
GB2442271B (en) * 2006-09-27 2011-06-15 Denis Eon Solomon An in vitro human skin assay protocol which directly uses the natural cellular interactions between un-manipulated autologous human epidermal and dermal cells
US8709081B2 (en) 2006-10-23 2014-04-29 Stemedica Cell Technologies, Inc. Cellular scaffold
US8105380B2 (en) * 2006-10-23 2012-01-31 Stemedica Cell Technologies, Inc. Cellular scaffold
US20080279830A1 (en) * 2007-05-08 2008-11-13 Xgene Corporation Spongy epithelial cell scaffold for vascularizing wounds
EP2582791B8 (de) * 2010-06-18 2018-05-23 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Neogenese von haarfollikeln
EP2991692B1 (de) 2013-05-03 2019-08-21 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Hautersatzstoffe und verfahren zur neubildung von haarfollikeln
KR101673424B1 (ko) * 2015-11-13 2016-11-07 호서대학교 산학협력단 외부자극 및 도포물질 휘산 방지용 보호장치
GB201715929D0 (en) * 2017-09-30 2017-11-15 Upside Biotechnologies Ltd Method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5988423A (ja) * 1982-11-09 1984-05-22 Nippon Chem Res Kk ヒト腫瘍細胞変性因子の製造方法
WO1997018296A1 (en) * 1995-11-15 1997-05-22 University Of Utah Novel method of culturing human epithelial cells for the identification of cancer therapeutics and diagnostics
US20010048917A1 (en) * 1998-03-09 2001-12-06 Warren Hoeffler Skin equivalent and methods of forming and using same

Also Published As

Publication number Publication date
EP1339831B1 (de) 2007-02-21
DE60126815D1 (de) 2007-04-05
US20020120950A1 (en) 2002-08-29
US6815202B2 (en) 2004-11-09
DE60126815T2 (de) 2007-11-15
EP1339831A1 (de) 2003-09-03
US20050118146A1 (en) 2005-06-02
WO2002046375A1 (en) 2002-06-13
AU2002230768A1 (en) 2002-06-18

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