ATE355053T1 - Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid - Google Patents

Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid

Info

Publication number: ATE355053T1
Authority: AT; Austria
Prior art keywords: propylene glycol; ionic surfactant; cyclosporine; pharmaceutical formulation; glycol ester
Prior art date: 2002-08-02

Application number

AT03766449T

Other languages

English (en)

Inventor

Satishchandra Punambhai Patel

Original Assignee

Satishchandra Punambhai Patel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-02

Filing date

2003-07-31

Publication date

2006-03-15

2003-07-31 Application filed by Satishchandra Punambhai Patel filed Critical Satishchandra Punambhai Patel

2006-03-15 Application granted granted Critical

2006-03-15 Publication of ATE355053T1 publication Critical patent/ATE355053T1/de

Links

DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 title abstract 6
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 3
108010036949 Cyclosporine Proteins 0.000 title abstract 3
229960001265 ciclosporin Drugs 0.000 title abstract 3
229930182912 cyclosporin Natural products 0.000 title abstract 2
239000002736 nonionic surfactant Substances 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 3
229930105110 Cyclosporin A Natural products 0.000 abstract 2
235000014113 dietary fatty acids Nutrition 0.000 abstract 2
239000000194 fatty acid Substances 0.000 abstract 2
229930195729 fatty acid Natural products 0.000 abstract 2
150000004665 fatty acids Chemical class 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000005690 diesters Chemical class 0.000 abstract 1
239000000839 emulsion Substances 0.000 abstract 1
239000012530 fluid Substances 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1
239000012456 homogeneous solution Substances 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dispersion Chemistry (AREA)
Tropical Medicine & Parasitology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT03766449T 2002-08-02 2003-07-31 Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid ATE355053T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB0218002A GB2391471B (en)	2002-08-02	2002-08-02	Pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
ATE355053T1 true ATE355053T1 (de)	2006-03-15

Family

ID=9941655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03766449T ATE355053T1 (de)	2002-08-02	2003-07-31	Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid

Country Status (12)

Country	Link
US (1)	US7670618B2 (de)
EP (1)	EP1551375B1 (de)
JP (1)	JP2006501208A (de)
KR (1)	KR101068255B1 (de)
AT (1)	ATE355053T1 (de)
AU (1)	AU2003248969A1 (de)
CA (1)	CA2494796C (de)
DE (1)	DE60312193T2 (de)
ES (1)	ES2285196T3 (de)
GB (1)	GB2391471B (de)
MX (1)	MXPA05001352A (de)
WO (1)	WO2004012716A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5858401A (en) *	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
KR100440209B1 (ko) *	2002-01-28	2004-07-14	용문산은행영농조합법인	은행꿀차 및 이의 제조방법
US7671017B2 (en) *	2004-07-14	2010-03-02	Novartis Ag	Use of a combination of cyclosporine and pegylated interferon for treating hepatitis C (HCV)
BRPI0518484A2 (pt) *	2004-11-24	2008-11-18	Merck & Co Inc	composiÇço, cÁpsula, e, processo para preparar a mesma
US7288520B2 (en) *	2005-07-13	2007-10-30	Allergan, Inc.	Cyclosporin compositions
US7202209B2 (en)	2005-07-13	2007-04-10	Allergan, Inc.	Cyclosporin compositions
US20070015691A1 (en)	2005-07-13	2007-01-18	Allergan, Inc.	Cyclosporin compositions
US20070015693A1 (en) *	2005-07-13	2007-01-18	Allergan, Inc.	Cyclosporin compositions
US7297679B2 (en)	2005-07-13	2007-11-20	Allergan, Inc.	Cyclosporin compositions
US7276476B2 (en) *	2005-07-13	2007-10-02	Allergan, Inc.	Cyclosporin compositions
US7501393B2 (en)	2005-07-27	2009-03-10	Allergan, Inc.	Pharmaceutical compositions comprising cyclosporins
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
US7745400B2 (en) *	2005-10-14	2010-06-29	Gregg Feinerman	Prevention and treatment of ocular side effects with a cyclosporin
US7988883B2 (en)	2006-02-10	2011-08-02	Dupont Tate & Lyle Bio Products Company, Llc	Heat transfer compositions comprising renewably-based biodegradable 1,3-propanediol
JP2011500512A (ja) *	2007-07-31	2011-01-06	リメリックバイオファーマ，インコーポレイティド	リン酸化ピロン類似体および方法
WO2009158031A2 (en) *	2008-06-27	2009-12-30	Limerick Biopharma, Inc.	Methods and compositions for therapeutic treatment
US20130317117A1 (en) *	2010-11-24	2013-11-28	Pharmaceutics International, Inc.	Self micro-emulsifying drug delivery system with increased bioavailability
JP6302671B2 (ja) *	2013-12-27	2018-03-28	花王株式会社	皮膚洗浄剤組成物
CN104115914A (zh) *	2014-07-21	2014-10-29	如皋市太阳肠衣食品有限公司	一种肠衣保鲜方法
CN104115912A (zh) *	2014-07-21	2014-10-29	如皋市太阳肠衣食品有限公司	一种肠衣氧化预处理方法
WO2017168416A1 (en) *	2016-03-28	2017-10-05	Vidac Pharma Ltd.	Stable pharmaceutical compositions for topical administration and uses thereof
BR112022007535A2 (pt)	2019-11-07	2022-07-12	Chugai Pharmaceutical Co Ltd	Composto peptídico cíclico tendo ação inibitória de kras

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2907460A1 (de)	1978-03-07	1979-09-13	Sandoz Ag	Neue resorbierbare galenische kompositionen
US5639724A (en)	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
US5342625A (en)	1988-09-16	1994-08-30	Sandoz Ltd.	Pharmaceutical compositions comprising cyclosporins
GB9405304D0 (en) *	1994-03-16	1994-04-27	Scherer Ltd R P	Delivery systems for hydrophobic drugs
US5858401A (en)	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
SK285019B6 (sk) *	1997-01-30	2006-04-06	Novartis Ag	Tvrdá želatínová tobolka
CA2283780A1 (en) *	1997-03-12	1998-09-17	Abbott Laboratories	Lipophilic binary systems for the administration of lipophilic compounds
ID25908A (id) *	1998-03-06	2000-11-09	Novartis Ag	Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
US6638522B1 (en) *	1998-12-11	2003-10-28	Pharmasolutions, Inc.	Microemulsion concentrate composition of cyclosporin
US6294192B1 (en) *	1999-02-26	2001-09-25	Lipocine, Inc.	Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6057289A (en)	1999-04-30	2000-05-02	Pharmasolutions, Inc.	Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system
EP1227793A1 (de) *	1999-11-02	2002-08-07	Cipla Ltd.	Cyclosporin formulierung
GB0008785D0 (en) *	2000-04-10	2000-05-31	Novartis Ag	Organic compounds
EP1170919A1 (de)	2000-07-04	2002-01-09	TELEFONAKTIEBOLAGET LM ERICSSON (publ)	Verfahren und System zur Verbesserung der Funktion eines Kommunikationssystems mit Schichtprotokollstapel
TW200409644A (en) *	2002-12-04	2004-06-16	Bio Max Inc	Improved carrier system for cyclosporin pharmaceutical compositions

2002
- 2002-08-02 GB GB0218002A patent/GB2391471B/en not_active Expired - Lifetime
2003
- 2003-07-31 AU AU2003248969A patent/AU2003248969A1/en not_active Abandoned
- 2003-07-31 MX MXPA05001352A patent/MXPA05001352A/es active IP Right Grant
- 2003-07-31 KR KR1020057001939A patent/KR101068255B1/ko not_active Expired - Fee Related
- 2003-07-31 ES ES03766449T patent/ES2285196T3/es not_active Expired - Lifetime
- 2003-07-31 WO PCT/GB2003/003304 patent/WO2004012716A1/en not_active Ceased
- 2003-07-31 EP EP03766449A patent/EP1551375B1/de not_active Expired - Lifetime
- 2003-07-31 JP JP2004525538A patent/JP2006501208A/ja active Pending
- 2003-07-31 AT AT03766449T patent/ATE355053T1/de not_active IP Right Cessation
- 2003-07-31 DE DE60312193T patent/DE60312193T2/de not_active Expired - Lifetime
- 2003-07-31 CA CA2494796A patent/CA2494796C/en not_active Expired - Fee Related
- 2003-08-04 US US10/632,970 patent/US7670618B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2494796C (en)	2012-03-27
GB0218002D0 (en)	2002-09-11
DE60312193T2 (de)	2007-11-08
JP2006501208A (ja)	2006-01-12
GB2391471B (en)	2005-05-04
GB2391471A (en)	2004-02-11
ES2285196T3 (es)	2007-11-16
DE60312193D1 (de)	2007-04-12
KR20050083608A (ko)	2005-08-26
US20040048789A1 (en)	2004-03-11
EP1551375A1 (de)	2005-07-13
CA2494796A1 (en)	2004-02-12
AU2003248969A1 (en)	2004-02-23
MXPA05001352A (es)	2005-10-05
US7670618B2 (en)	2010-03-02
WO2004012716A1 (en)	2004-02-12
KR101068255B1 (ko)	2011-09-28
EP1551375B1 (de)	2007-02-28

Legal Events

Date	Code	Title	Description
2007-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE355053T1 (de)	2006-03-15	Pharmazeutische formulierung mit cyclosporin, propylenglycol-ester und nichtionischem tensid
JP4761093B2 (ja)	2011-08-31	オメガ−３脂肪酸油を含む医薬組成物
EP0790822B1 (de)	2002-03-06	MITTEL MIT GESTEUERTER FREISETZUNG, DIE EINE UMGEKEHRTE MICELLARE (L2) STRUKTUR ODER EINE NORMALE MICELLARE (l1) STRUKTUR BILDEN
CA2185347A1 (en)	1995-09-21	A carrier for hydrophobic drugs and a pharmaceutical composition based thereon
EP2062571B1 (de)	2012-11-14	Selbstemulgierende pharmazeutische Zusammensetzung mit verbesserter Bioverfügbarkeit
KR101344557B1 (ko)	2013-12-26	베시클 함유 조성물
AR015729A1 (es)	2001-05-16	Una composicion en la forma de un preconcentrado en emulsion o en microemulsion para la administracion oral, el uso de la misma para la fabricacion de unmedicamento y un metodo para reducir la variabilidad de los niveles de biodisponibilidad de una ciclosporina o un macrolido.
DE60028384D1 (de)	2006-07-06	Propofol enthaltende anästhetische zusammensetzung zur intravenösen injektion
NZ512287A (en)	2002-12-20	Pharmaceutical compositions comprising a lipophilic drug in a propylene glycol ester of a higher fatty acid carrier, where 60% of the ester is a monoester
ES2168271T3 (es)	2002-06-16	Composiciones farmaceuticas que contienen ciclosporinas.
WO1999056727A2 (en)	1999-11-11	Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems
DK0957942T3 (da)	2004-10-25	Polymer-lipid-mikroindkapslede gasser til anvendelse som billeddannende midler
ATE152613T1 (de)	1997-05-15	Zusammensetzung, die bei peroraler verabreichung eine mikroemulsion bildet
DE60024429D1 (de)	2006-01-05	Orale pharmazeutische zusammensetzungen, die langkettige triglyceride und lipophile tenside enthalten
WO2007144139A2 (en)	2007-12-21	Pharmaceutical compositions with biological barriers permeation enhancing properties
EP1682091A1 (de)	2006-07-26	Zusammensetzungen von lipiden und kationischen peptiden
AU667483B2 (en)	1996-03-28	W/O microemulsions
CN101528196A (zh)	2009-09-09	用于生物利用性差的药物的自乳化组合物
IL143604A0 (en)	2002-04-21	Dispersable concentrate for the delivery of cyclosporin
DE60326989D1 (de)	2009-05-14	Orale pharmazeutische zubereitungen enthaltend cyclosporin
ATE198547T1 (de)	2001-01-15	Mizelleförmige feinteilige pharmazeutische zusammensetzungen
JP2014214134A (ja)	2014-11-17	水性組成物
Miyamoto et al.	1999	Preparation of gadolinium-containing emulsions stabilized with phosphatidylcholine-surfactant mixtures for neutron-capture therapy
CA2030204C (en)	1996-02-27	Pharmaceutical compositions of tebufelone
JP4048389B2 (ja)	2008-02-20	シクロスポリン軟カプセル剤