ATE355281T1 - 1,4,7,10-tetraazacyclododecan-1,4-diessigsäure - Google Patents

1,4,7,10-tetraazacyclododecan-1,4-diessigsäure

Info

Publication number
ATE355281T1
ATE355281T1 AT98966652T AT98966652T ATE355281T1 AT E355281 T1 ATE355281 T1 AT E355281T1 AT 98966652 T AT98966652 T AT 98966652T AT 98966652 T AT98966652 T AT 98966652T AT E355281 T1 ATE355281 T1 AT E355281T1
Authority
AT
Austria
Prior art keywords
diacetic acid
anions
well
tetraazacyclododecan
salts
Prior art date
Application number
AT98966652T
Other languages
English (en)
Inventor
Renato Geremia
Marcella Murru
Giorgio Ripa
Vittorio Valle
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Application granted granted Critical
Publication of ATE355281T1 publication Critical patent/ATE355281T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A61K49/108—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA the metal complex being Gd-DOTA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98966652T 1997-12-30 1998-12-21 1,4,7,10-tetraazacyclododecan-1,4-diessigsäure ATE355281T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002895A IT1297034B1 (it) 1997-12-30 1997-12-30 Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico

Publications (1)

Publication Number Publication Date
ATE355281T1 true ATE355281T1 (de) 2006-03-15

Family

ID=11378473

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98966652T ATE355281T1 (de) 1997-12-30 1998-12-21 1,4,7,10-tetraazacyclododecan-1,4-diessigsäure

Country Status (8)

Country Link
US (1) US6417354B1 (de)
EP (1) EP1045838B1 (de)
JP (1) JP4460766B2 (de)
AT (1) ATE355281T1 (de)
AU (1) AU2415699A (de)
DE (1) DE69837219T2 (de)
IT (1) IT1297034B1 (de)
WO (1) WO1999035134A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050187126A1 (en) * 2002-08-27 2005-08-25 Busch Daryle H. Catalysts and methods for catalytic oxidation
ZA981883B (en) * 1997-03-07 1998-09-01 Univ Kansas Catalysts and methods for catalytic oxidation
TR199902673T2 (en) * 1997-03-07 2000-04-21 The Procter & Gamble Company A�art�c� bile�imler.
US20080125344A1 (en) * 2006-11-28 2008-05-29 Daryle Hadley Busch Bleach compositions
US20030017941A1 (en) * 1997-03-07 2003-01-23 The Procter & Gamble Company Catalysts and methods for catalytic oxidation
IT1297035B1 (it) * 1997-12-30 1999-08-03 Bracco Spa Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico
US20040048763A1 (en) * 2002-08-27 2004-03-11 The Procter & Gamble Co. Bleach compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132409A (en) * 1987-01-12 1992-07-21 Bracco Industria Chimica S.P.A. Macrocyclic chelating agents and chelates thereof
IT1224416B (it) * 1987-12-24 1990-10-04 Bracco Ind Chimica Spa Chelanti macrociclici e loro chelati
US5410043A (en) * 1991-12-06 1995-04-25 Schering Aktiengesellschaft Process for the production of mono-N-substituted tetraaza macrocycles
EP0730616B1 (de) * 1993-11-26 2003-02-05 Dow Global Technologies Inc. Verfahren zur herstellung von polyazamacrocylen
US5833948A (en) * 1995-06-15 1998-11-10 Bracco Research S.A. Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
BR9708470A (pt) * 1996-04-01 1999-04-13 Epix Medical Inc Agentes de contraste bioativados para formação de imagem para diagnósticos

Also Published As

Publication number Publication date
US6417354B1 (en) 2002-07-09
DE69837219D1 (de) 2007-04-12
EP1045838B1 (de) 2007-02-28
IT1297034B1 (it) 1999-08-03
WO1999035134A1 (en) 1999-07-15
DE69837219T2 (de) 2007-07-05
JP2002500219A (ja) 2002-01-08
ITMI972895A1 (it) 1999-06-30
AU2415699A (en) 1999-07-26
JP4460766B2 (ja) 2010-05-12
EP1045838A1 (de) 2000-10-25

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties