ATE356215T1 - Verfahren zur herstellung von 2,4-didesoxyhexosen und 2,4,6-tridesoxyhexosen - Google Patents

Verfahren zur herstellung von 2,4-didesoxyhexosen und 2,4,6-tridesoxyhexosen

Info

Publication number: ATE356215T1
Authority: AT; Austria
Prior art keywords: substituted; trideoxyhexose; dideoxyhexose; preparation; unsubstituted
Prior art date: 2001-07-12

Application number

AT02746200T

Other languages

English (en)

Inventor

Joannes Gerardus Theo Kierkels

Daniel Mink

Sven Panke

Franciscus Alphons Mari Lommen

Dennis Heemskerk

Original Assignee

Dsm Ip Assets Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-12

Filing date

2002-07-09

Publication date

2007-03-15

2001-07-12 Priority claimed from NL1018525A external-priority patent/NL1018525C2/nl

2001-12-20 Priority claimed from NL1019622A external-priority patent/NL1019622C2/nl

2002-07-09 Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv

2007-03-15 Application granted granted Critical

2007-03-15 Publication of ATE356215T1 publication Critical patent/ATE356215T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
HNPRLDIJKHZNSL-RITPCOANSA-N (3s,5s)-3,5,6-trihydroxyhexanal Chemical compound OC[C@@H](O)C[C@H](O)CC=O HNPRLDIJKHZNSL-RITPCOANSA-N 0.000 abstract 3
150000001299 aldehydes Chemical class 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
150000001728 carbonyl compounds Chemical class 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
239000011541 reaction mixture Substances 0.000 abstract 2
102000001390 Fructose-Bisphosphate Aldolase Human genes 0.000 abstract 1
108010068561 Fructose-Bisphosphate Aldolase Proteins 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
DFVFTMTWCUHJBL-BQBZGAKWSA-N statine Chemical compound CC(C)C[C@H](N)[C@@H](O)CC(O)=O DFVFTMTWCUHJBL-BQBZGAKWSA-N 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT02746200T 2001-07-12 2002-07-09 Verfahren zur herstellung von 2,4-didesoxyhexosen und 2,4,6-tridesoxyhexosen ATE356215T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL1018525A NL1018525C2 (nl)	2001-07-12	2001-07-12	Werkwijze voor de bereiding van 2,4-dideoxyhexosen en 2,4,6-trideoxyhexosen.
NL1019622A NL1019622C2 (nl)	2001-12-20	2001-12-20	Werkwijze voor de bereiding van 2,4-dideoxyhexosen en 2,4,6-trideoxyhexosen.

Publications (1)

Publication Number	Publication Date
ATE356215T1 true ATE356215T1 (de)	2007-03-15

Family

ID=26643375

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02746200T ATE356215T1 (de)	2001-07-12	2002-07-09	Verfahren zur herstellung von 2,4-didesoxyhexosen und 2,4,6-tridesoxyhexosen

Country Status (12)

Country	Link
US (2)	US6964863B2 (de)
EP (1)	EP1404844B1 (de)
JP (1)	JP4248392B2 (de)
CN (1)	CN1300132C (de)
AT (1)	ATE356215T1 (de)
CA (1)	CA2448517A1 (de)
DE (1)	DE60218678T2 (de)
DK (1)	DK1404844T3 (de)
ES (1)	ES2282433T3 (de)
HU (1)	HU228734B1 (de)
MX (1)	MXPA04000310A (de)
WO (1)	WO2003006656A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004027075A2 (en) *	2002-09-20	2004-04-01	Diversa Corporation	Chemoenzymatic methods for the synthesis of statins and stain intermediates
US7402710B2 (en)	2004-03-29	2008-07-22	Mitsui Chemicals, Inc.	Process for producing chiral hydroxyaldehyde compounds
KR100807523B1 (ko)	2004-12-31	2008-02-26	주식회사유한양행	광학 활성 디올 유도체의 신규 제조방법
WO2007137816A1 (en) *	2006-05-30	2007-12-06	Dsm Ip Assets B.V.	Process for the preparation of epoxide intermediates for pharmaceutical compounds such as statins
US8642783B2 (en)	2007-08-03	2014-02-04	Pfizer Inc.	Process for preparing chiral compounds
WO2009092702A2 (en) *	2008-01-23	2009-07-30	Lek Pharmaceuticals D.D.	((2s,4r)-4,6-dihydroxytetrahydro-2h-pyran-2-yl)methyl carboxylate and process for the production thereof
ES2623495T3 (es)	2011-12-09	2017-07-11	Dsm Sinochem Pharmaceuticals Netherlands B.V.	Procedimiento para la preparación de un tioprecursor para estatinas
HK1201062A1 (en)	2011-12-09	2015-08-21	中化帝斯曼制药有限公司荷兰公司	Process for the preparation of a statin precursor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5278313A (en) *	1992-03-27	1994-01-11	E. R. Squibb & Sons, Inc.	Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
US5795749A (en) *	1995-04-05	1998-08-18	The Scripps Research Institution	Use of 2-deoxyribose-5-phosphate aldolase to prepare 2-deoxyfucose, analogues and derivatives
HUP0101122A3 (en)	1998-08-05	2006-02-28	Kaneka Corp	Process for the preparation of optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivatives

2002
- 2002-07-09 CA CA002448517A patent/CA2448517A1/en not_active Abandoned
- 2002-07-09 WO PCT/NL2002/000450 patent/WO2003006656A2/en not_active Ceased
- 2002-07-09 AT AT02746200T patent/ATE356215T1/de not_active IP Right Cessation
- 2002-07-09 MX MXPA04000310A patent/MXPA04000310A/es active IP Right Grant
- 2002-07-09 JP JP2003512413A patent/JP4248392B2/ja not_active Expired - Fee Related
- 2002-07-09 DE DE60218678T patent/DE60218678T2/de not_active Expired - Lifetime
- 2002-07-09 DK DK02746200T patent/DK1404844T3/da active
- 2002-07-09 US US10/481,303 patent/US6964863B2/en not_active Expired - Lifetime
- 2002-07-09 CN CNB028139429A patent/CN1300132C/zh not_active Expired - Lifetime
- 2002-07-09 EP EP02746200A patent/EP1404844B1/de not_active Expired - Lifetime
- 2002-07-09 ES ES02746200T patent/ES2282433T3/es not_active Expired - Lifetime
- 2002-07-09 HU HU0401577A patent/HU228734B1/hu not_active IP Right Cessation
2005
- 2005-08-17 US US11/206,574 patent/US7439046B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE60218678T2 (de)	2008-02-14
US20050287650A1 (en)	2005-12-29
US6964863B2 (en)	2005-11-15
EP1404844B1 (de)	2007-03-07
JP2005500838A (ja)	2005-01-13
US7439046B2 (en)	2008-10-21
US20040171125A1 (en)	2004-09-02
WO2003006656A2 (en)	2003-01-23
CN1526019A (zh)	2004-09-01
HUP0401577A2 (hu)	2004-11-29
CA2448517A1 (en)	2003-01-23
WO2003006656A3 (en)	2003-12-11
EP1404844A2 (de)	2004-04-07
HUP0401577A3 (en)	2010-03-29
HU228734B1 (hu)	2013-05-28
DK1404844T3 (da)	2007-06-04
ES2282433T3 (es)	2007-10-16
MXPA04000310A (es)	2004-05-04
DE60218678D1 (de)	2007-04-19
CN1300132C (zh)	2007-02-14
JP4248392B2 (ja)	2009-04-02

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Legal Events

Date

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Title

Description

2007-08-15

UEP

Publication of translation of european patent specification

Ref document number: 1404844

Country of ref document: EP

2010-04-15

REN

Ceased due to non-payment of the annual fee