ATE358185T1 - Mutationsanalyse mittels pcr und massenspektrometrie - Google Patents

Mutationsanalyse mittels pcr und massenspektrometrie

Info

Publication number: ATE358185T1
Authority: AT; Austria
Prior art keywords: pcr; primers; linkers; analysis; mass spectrometric
Prior art date: 2002-02-01

Application number

AT02002522T

Other languages

English (en)

Inventor

Jochen Franzen

Original Assignee

Bruker Daltonik Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-01

Filing date

2002-02-01

Publication date

2007-04-15

2002-02-01 Application filed by Bruker Daltonik Gmbh filed Critical Bruker Daltonik Gmbh

2007-04-15 Application granted granted Critical

2007-04-15 Publication of ATE358185T1 publication Critical patent/ATE358185T1/de

Links

238000004949 mass spectrometry Methods 0.000 title abstract 3
230000035772 mutation Effects 0.000 title abstract 3
238000004458 analytical method Methods 0.000 title abstract 2
238000000034 method Methods 0.000 abstract 3
238000003752 polymerase chain reaction Methods 0.000 abstract 3
108091034117 Oligonucleotide Proteins 0.000 abstract 2
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 2
230000003321 amplification Effects 0.000 abstract 2
238000003199 nucleic acid amplification method Methods 0.000 abstract 2
108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
239000006227 byproduct Substances 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
102000054765 polymorphisms of proteins Human genes 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

AT02002522T 2002-02-01 2002-02-01 Mutationsanalyse mittels pcr und massenspektrometrie ATE358185T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02002522A EP1333101B1 (de)	2002-02-01	2002-02-01	Mutationsanalyse Mittels PCR und Massenspektrometrie

Publications (1)

Publication Number	Publication Date
ATE358185T1 true ATE358185T1 (de)	2007-04-15

Family

ID=8185417

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02002522T ATE358185T1 (de)	2002-02-01	2002-02-01	Mutationsanalyse mittels pcr und massenspektrometrie

Country Status (4)

Country	Link
US (1)	US6750022B2 (de)
EP (1)	EP1333101B1 (de)
AT (1)	ATE358185T1 (de)
DE (1)	DE60219132T2 (de)

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US8073627B2 (en)	2001-06-26	2011-12-06	Ibis Biosciences, Inc.	System for indentification of pathogens
US7217510B2 (en)	2001-06-26	2007-05-15	Isis Pharmaceuticals, Inc.	Methods for providing bacterial bioagent characterizing information
US8046171B2 (en)	2003-04-18	2011-10-25	Ibis Biosciences, Inc.	Methods and apparatus for genetic evaluation
US8057993B2 (en)	2003-04-26	2011-11-15	Ibis Biosciences, Inc.	Methods for identification of coronaviruses
US8158354B2 (en)	2003-05-13	2012-04-17	Ibis Biosciences, Inc.	Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US7964343B2 (en)	2003-05-13	2011-06-21	Ibis Biosciences, Inc.	Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8242254B2 (en)	2003-09-11	2012-08-14	Ibis Biosciences, Inc.	Compositions for use in identification of bacteria
US8546082B2 (en)	2003-09-11	2013-10-01	Ibis Biosciences, Inc.	Methods for identification of sepsis-causing bacteria
US8097416B2 (en)	2003-09-11	2012-01-17	Ibis Biosciences, Inc.	Methods for identification of sepsis-causing bacteria
US7666592B2 (en)	2004-02-18	2010-02-23	Ibis Biosciences, Inc.	Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en)	2004-03-03	2012-02-21	Ibis Biosciences, Inc.	Compositions for use in identification of alphaviruses
ES2641832T3 (es)	2004-05-24	2017-11-14	Ibis Biosciences, Inc.	Espectrometría de masas con filtración de iones selectiva por establecimiento de umbrales digitales
US20050266411A1 (en)	2004-05-25	2005-12-01	Hofstadler Steven A	Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en)	2004-07-14	2010-10-12	Ibis Biosciences, Inc.	Methods for repairing degraded DNA
WO2006135400A2 (en)	2004-08-24	2006-12-21	Isis Pharmaceuticals, Inc.	Methods for rapid identification of recombinant organisms
US8084207B2 (en)	2005-03-03	2011-12-27	Ibis Bioscience, Inc.	Compositions for use in identification of papillomavirus
US20060205040A1 (en)	2005-03-03	2006-09-14	Rangarajan Sampath	Compositions for use in identification of adventitious viruses
JP2009502137A (ja)	2005-07-21	2009-01-29	アイシスファーマシューティカルズインコーポレイティッド	核酸変種の迅速な同定および定量のための方法
GB0601031D0 (en) *	2006-01-18	2006-03-01	Novartis Ag	Organic compounds
WO2007115059A2 (en)	2006-03-29	2007-10-11	Merial Limited	Vaccine against streptococci
EP2010679A2 (de)	2006-04-06	2009-01-07	Ibis Biosciences, Inc.	Zusammensetzungen für die identifizierung von pilzen
US9149473B2 (en)	2006-09-14	2015-10-06	Ibis Biosciences, Inc.	Targeted whole genome amplification method for identification of pathogens
EP2126132B1 (de)	2007-02-23	2013-03-20	Ibis Biosciences, Inc.	Verfahren für schnelle forensische dna-analyse
WO2008151023A2 (en)	2007-06-01	2008-12-11	Ibis Biosciences, Inc.	Methods and compositions for multiple displacement amplification of nucleic acids
US8550694B2 (en)	2008-09-16	2013-10-08	Ibis Biosciences, Inc.	Mixing cartridges, mixing stations, and related kits, systems, and methods
US8148163B2 (en)	2008-09-16	2012-04-03	Ibis Biosciences, Inc.	Sample processing units, systems, and related methods
WO2010033625A1 (en)	2008-09-16	2010-03-25	Ibis Biosciences, Inc.	Microplate handling systems and related computer program products and methods
EP2396803A4 (de)	2009-02-12	2016-10-26	Ibis Biosciences Inc	Ionisationssondenanordnungen
US9719083B2 (en)	2009-03-08	2017-08-01	Ibis Biosciences, Inc.	Bioagent detection methods
WO2010114842A1 (en)	2009-03-30	2010-10-07	Ibis Biosciences, Inc.	Bioagent detection systems, devices, and methods
EP2454000A4 (de)	2009-07-17	2016-08-10	Ibis Biosciences Inc	Systeme zur identifizierung von biowirkstoffen
US8950604B2 (en)	2009-07-17	2015-02-10	Ibis Biosciences, Inc.	Lift and mount apparatus
WO2011014811A1 (en)	2009-07-31	2011-02-03	Ibis Biosciences, Inc.	Capture primers and capture sequence linked solid supports for molecular diagnostic tests
EP3098325A1 (de)	2009-08-06	2016-11-30	Ibis Biosciences, Inc.	Basenzusammensetzungen ohne massenbestimmung zur nukleinsäureerkennung
EP2488656B1 (de)	2009-10-15	2015-06-03	Ibis Biosciences, Inc.	Mehrfache verschiebungsverstärkung
US9758840B2 (en)	2010-03-14	2017-09-12	Ibis Biosciences, Inc.	Parasite detection via endosymbiont detection
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2002
- 2002-02-01 EP EP02002522A patent/EP1333101B1/de not_active Expired - Lifetime
- 2002-02-01 AT AT02002522T patent/ATE358185T1/de not_active IP Right Cessation
- 2002-02-01 DE DE60219132T patent/DE60219132T2/de not_active Expired - Lifetime
- 2002-02-20 US US10/079,271 patent/US6750022B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE60219132T2 (de)	2007-12-13
EP1333101B1 (de)	2007-03-28
EP1333101A1 (de)	2003-08-06
DE60219132D1 (de)	2007-05-10
US6750022B2 (en)	2004-06-15
US20030148293A1 (en)	2003-08-07

Legal Events

Date	Code	Title	Description
2007-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE358185T1 (de)	2007-04-15	Mutationsanalyse mittels pcr und massenspektrometrie
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