ATE359294T1 - Toxinrezeptoren aus zonula occludens - Google Patents

Toxinrezeptoren aus zonula occludens

Info

Publication number
ATE359294T1
ATE359294T1 AT98904957T AT98904957T ATE359294T1 AT E359294 T1 ATE359294 T1 AT E359294T1 AT 98904957 T AT98904957 T AT 98904957T AT 98904957 T AT98904957 T AT 98904957T AT E359294 T1 ATE359294 T1 AT E359294T1
Authority
AT
Austria
Prior art keywords
zonula occludens
toxin receptors
receptors
toxin
zonula
Prior art date
Application number
AT98904957T
Other languages
English (en)
Inventor
Alessio Fasano
Original Assignee
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/803,364 external-priority patent/US5864014A/en
Application filed by Univ Maryland filed Critical Univ Maryland
Application granted granted Critical
Publication of ATE359294T1 publication Critical patent/ATE359294T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/909—Vibrio
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98904957T 1997-02-20 1998-02-18 Toxinrezeptoren aus zonula occludens ATE359294T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/803,364 US5864014A (en) 1997-02-20 1997-02-20 Zonula occludens toxin receptor
US09/024,198 US5912323A (en) 1997-02-20 1998-02-17 Zonula occludens toxin receptors

Publications (1)

Publication Number Publication Date
ATE359294T1 true ATE359294T1 (de) 2007-05-15

Family

ID=26698164

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98904957T ATE359294T1 (de) 1997-02-20 1998-02-18 Toxinrezeptoren aus zonula occludens

Country Status (9)

Country Link
US (2) US5912323A (de)
EP (1) EP1007553B1 (de)
JP (1) JP4215827B2 (de)
AT (1) ATE359294T1 (de)
AU (1) AU6270298A (de)
CA (1) CA2281617A1 (de)
DE (1) DE69837546T2 (de)
ES (1) ES2285762T3 (de)
WO (1) WO1998037096A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458925B1 (en) 1998-08-03 2002-10-01 University Of Maryland, Baltimore Peptide antagonists of zonulin and methods for use of the same
EP1249244A1 (de) 2001-04-13 2002-10-16 Universiteit Gent Therapeutische Zusammensetzungen zur Behandlung einer g-actin / f-actin-gleichgewicht vermittelten Erkrankung, z.b. einer respiratorischen Erkrankung
JP2005526772A (ja) 2002-03-15 2005-09-08 リテック 消化機能病理を処置するための組成物
FR2844201A1 (fr) * 2002-09-06 2004-03-12 Rytek Compositions pour le traitement de pathologies fonctionnelles digestives
AU2003268489B2 (en) 2002-09-06 2008-01-24 Promega Corporation Method for detecting transferase enzymatic activity
JP4485470B2 (ja) 2002-12-23 2010-06-23 プロメガ コーポレイション ルシフェラーゼ酵素活性を保護するための方法及びキット
EP1648917A4 (de) * 2003-07-15 2008-11-12 Univ Maryland Agonistpolypeptid des rezeptors für zot und zonulin
US20080038843A1 (en) * 2006-08-11 2008-02-14 University Of Maryland - Baltimore Method of diagnosing celiac disease
WO2006088491A2 (en) * 2004-06-29 2006-08-24 Massachusetts Institute Of Technology Methods and compositions related to the modulation of intercellular junctions
FR2879100B1 (fr) 2004-12-09 2007-07-06 Lionel Bueno Compositions pour le traitement des pathologies oculaires de surface et de la retine
TW200637573A (en) * 2005-01-14 2006-11-01 Univ Maryland Peptide for delivery of mucosal vaccines
AR057058A1 (es) * 2005-06-09 2007-11-14 Alba Therapeutics Corp Metodo para usar antagonistas de zonulina para prevenir la perdida o para regenerar celulas pancreaticas
ES2459018T3 (es) 2006-02-09 2014-05-07 Alba Therapeutics Corporation Formulaciones de efectores de la unión estrecha
WO2008043107A2 (en) * 2006-10-06 2008-04-10 Alba Therapeutics Corporation Use of tight junction antagonists to treat inflammatory bowel disease
US8034776B2 (en) * 2006-10-26 2011-10-11 Alba Therapeutics Corporation Materials and methods for the treatment of celiac disease
US20100144646A1 (en) * 2006-11-03 2010-06-10 Blake Paterson Method of diagnosing and treating asthma
US8728491B2 (en) * 2007-05-07 2014-05-20 Alba Therapeutics Corporation Transcutaneous delivery of therapeutic agents
US20110201543A1 (en) * 2007-06-29 2011-08-18 Blake Paterson Use of tight junction antagonists in the treatment of acute lung injury and acute respiratory distress
US8198233B2 (en) 2007-07-26 2012-06-12 Alba Therapeutics Corporation Synthetic peptides that enhance tight junction permeability

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216126A (en) * 1991-06-19 1993-06-01 Genentech, Inc. Receptor polypeptides and their production and uses
US5665389A (en) * 1995-05-24 1997-09-09 University Of Maryland At Baltimore Oral dosage composition for intestinal delivery and method of treating diabetes

Also Published As

Publication number Publication date
WO1998037096A1 (en) 1998-08-27
US5912323A (en) 1999-06-15
CA2281617A1 (en) 1998-08-27
AU6270298A (en) 1998-09-09
JP2001518077A (ja) 2001-10-09
EP1007553A4 (de) 2004-09-22
EP1007553B1 (de) 2007-04-11
ES2285762T3 (es) 2007-11-16
DE69837546T2 (de) 2007-12-27
DE69837546D1 (de) 2007-05-24
US5948629A (en) 1999-09-07
JP4215827B2 (ja) 2009-01-28
EP1007553A1 (de) 2000-06-14

Similar Documents

Publication Publication Date Title
DE69837546D1 (de) Toxinrezeptoren aus zonula occludens
DE69737592D1 (de) Mittel gegen juckreiz
BR0112701B1 (pt) retentor de aba cranial.
ID29552A (id) Senyawa-senyawa triazola dan penggunaannya
TR200200205T2 (tr) MEK inhibitörleri kullanılarak kronik ağrının tedavi edilmesi
ATE264863T1 (de) 28-epirapaloge
BR9916798A (pt) 4-arilamino, 4-arilóxi e 4-ariltio diarilaminas e seus derivados como inibidores seletivos de mek
IT1317757B1 (it) Metodo per la preparazione di idrocarburi idrogenati.
DK0920429T3 (da) Substituerede pyrido- eller pyrimidoholdige, 6,6- eller 6,7-bicykliske derivater
CO5210911A1 (es) Trifluorbutenos nematicidas
DK1355889T3 (da) Substituerede triazoldiaminderivater som kinaseinhibitorer
EA200001129A2 (ru) Способ получения 4-карбоксиамино-2-замещенного-1,2,3,4-тетрагидрохинолина
BR0114903A (pt) 7-azaindóis, sua aplicação como inibidores da fosfodiesterase 4 e processos para a sua preparação
TR199800608A3 (tr) Propanolamin türevleri, bunlarin üretim usulü.
DK0971922T3 (da) Tetrahydropyrido-forbindelser
TR200001102T2 (tr) İkameli tetrahidropirimidinen türevleri, üretimleri ve kullanımları.
WO2001030330A3 (en) Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
DK1144666T3 (da) Replikationsdeficient baculovirusekspressionssystem
DE69628458D1 (de) 25-hydroxy-16-ene-26,27-bishome-cholecalceriferol derivate
SE9803107D0 (sv) Novel Compunds
TR199902914T2 (xx) �zole sistolik hipertansiyonu tedavi y�ntemi.
ITPD950052V0 (it) Dispositivo aspirante, particolarmente per w.c.
ITBO970065A0 (it) Dispositivo per la formazione di gruppi di sigarette.
ITRE20020101A1 (it) Sistema per la produzione di idrogeno da idrocarburi.
YU47301A (sh) Diarilamini sa supstituisanim 1-heterociklom

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties