ATE359830T1 - Chemisch definierten nicht-polymer wertigen plattformmolokülen und ihren konjugaten - Google Patents
Chemisch definierten nicht-polymer wertigen plattformmolokülen und ihren konjugatenInfo
- Publication number
- ATE359830T1 ATE359830T1 AT93309720T AT93309720T ATE359830T1 AT E359830 T1 ATE359830 T1 AT E359830T1 AT 93309720 T AT93309720 T AT 93309720T AT 93309720 T AT93309720 T AT 93309720T AT E359830 T1 ATE359830 T1 AT E359830T1
- Authority
- AT
- Austria
- Prior art keywords
- conjugates
- molocules
- chemically defined
- defined non
- chemically
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/118,055 US6060056A (en) | 1991-02-08 | 1993-09-08 | Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule |
| US14259893A | 1993-10-22 | 1993-10-22 | |
| US08/152,506 US5552391A (en) | 1990-01-16 | 1993-11-15 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| EP93309288 | 1993-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE359830T1 true ATE359830T1 (de) | 2007-05-15 |
Family
ID=38015477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93309720T ATE359830T1 (de) | 1993-09-08 | 1993-12-03 | Chemisch definierten nicht-polymer wertigen plattformmolokülen und ihren konjugaten |
Country Status (5)
| Country | Link |
|---|---|
| EP (2) | EP0642798B1 (de) |
| AT (1) | ATE359830T1 (de) |
| DE (1) | DE69334133T2 (de) |
| DK (1) | DK0642798T3 (de) |
| ES (1) | ES2282988T3 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552391A (en) * | 1990-01-16 | 1996-09-03 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| ATE359830T1 (de) * | 1993-09-08 | 2007-05-15 | Jolla Pharma | Chemisch definierten nicht-polymer wertigen plattformmolokülen und ihren konjugaten |
| KR100361933B1 (ko) | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| US5874409A (en) * | 1995-06-07 | 1999-02-23 | La Jolla Pharmaceutical Company | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
| US6410775B1 (en) | 1995-06-07 | 2002-06-25 | La Jolla Pharmaceutical Company | APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies |
| WO1997006166A1 (en) * | 1995-08-03 | 1997-02-20 | Dade Chemistry Systems Inc. | Quinidine conjugates and their use in immunoassays |
| KR20000016414A (ko) * | 1996-06-06 | 2000-03-25 | 와이즈먼 앤드루 | Apl 면역반응성 펩티드, 그것의 콘주게이트 및 apl항체-매개병변의 치료방법 |
| EP0855403A1 (de) * | 1996-06-10 | 1998-07-29 | Laboratory of Molecular Biophotonics | Photosplatbare zyklische oligonukleotide |
| US7094943B2 (en) * | 1998-04-27 | 2006-08-22 | Hubert Köster | Solution phase biopolymer synthesis |
| US6858210B1 (en) | 1998-06-09 | 2005-02-22 | La Jolla Pharmaceutical Co. | Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same |
| US6458953B1 (en) | 1998-12-09 | 2002-10-01 | La Jolla Pharmaceutical Company | Valency platform molecules comprising carbamate linkages |
| US6399578B1 (en) * | 1998-12-09 | 2002-06-04 | La Jolla Pharmaceutical Company | Conjugates comprising galactose α1,3 galactosyl epitopes and methods of using same |
| CA2376057A1 (en) * | 1999-06-08 | 2000-12-14 | La Jolla Pharmaceutical Company | Valency platform molecules comprising aminooxy groups |
| CN1399562A (zh) * | 1999-11-28 | 2003-02-26 | 拉卓拉药物公司 | 基于抗体亲和力来治疗狼疮的方法及使用这种方法的筛选方法和组合物 |
| CA2414076A1 (en) * | 2000-06-08 | 2001-12-13 | La Jolla Pharmaceutical Company | Multivalent platform molecules comprising high molecular weight polyethylene oxide |
| CN103037903A (zh) * | 2010-05-18 | 2013-04-10 | 天蓝制药公司 | 用于治疗自身免疫性疾病或其它疾病的组合物和方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3676670D1 (de) * | 1985-06-26 | 1991-02-07 | Cetus Corp | Solubilisierung von proteinen fuer pharmazeutische zusammensetzungen mittels polymerkonjugierung. |
| US4904582A (en) * | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
| US5552391A (en) * | 1990-01-16 | 1996-09-03 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| US5162515A (en) * | 1990-01-16 | 1992-11-10 | La Jolla Pharmaceutical Company | Conjugates of biologically stable polymers and polynucleotides for treating systemic lupus erythematosus |
| JPH04218000A (ja) * | 1990-02-13 | 1992-08-07 | Kirin Amgen Inc | 修飾ポリペプチド |
| ATE359830T1 (de) * | 1993-09-08 | 2007-05-15 | Jolla Pharma | Chemisch definierten nicht-polymer wertigen plattformmolokülen und ihren konjugaten |
-
1993
- 1993-12-03 AT AT93309720T patent/ATE359830T1/de not_active IP Right Cessation
- 1993-12-03 DK DK93309720T patent/DK0642798T3/da active
- 1993-12-03 ES ES93309720T patent/ES2282988T3/es not_active Expired - Lifetime
- 1993-12-03 EP EP93309720A patent/EP0642798B1/de not_active Expired - Lifetime
- 1993-12-03 EP EP07004965A patent/EP1808183A3/de not_active Withdrawn
- 1993-12-03 DE DE69334133T patent/DE69334133T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69334133T2 (de) | 2007-12-27 |
| HK1014240A1 (en) | 1999-09-24 |
| DE69334133D1 (de) | 2007-05-31 |
| DK0642798T3 (da) | 2007-09-10 |
| EP1808183A3 (de) | 2009-07-01 |
| EP0642798A2 (de) | 1995-03-15 |
| EP0642798A3 (de) | 1998-09-16 |
| ES2282988T3 (es) | 2007-10-16 |
| EP0642798B1 (de) | 2007-04-18 |
| EP1808183A2 (de) | 2007-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0642798 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |