ATE360030T1 - Polymorphismen der kationentransporter octn1 und octn2 welche mit entzündlichen darmerkrankungen in zusammenhang stehen - Google Patents
Polymorphismen der kationentransporter octn1 und octn2 welche mit entzündlichen darmerkrankungen in zusammenhang stehenInfo
- Publication number
- ATE360030T1 ATE360030T1 AT02781695T AT02781695T ATE360030T1 AT E360030 T1 ATE360030 T1 AT E360030T1 AT 02781695 T AT02781695 T AT 02781695T AT 02781695 T AT02781695 T AT 02781695T AT E360030 T1 ATE360030 T1 AT E360030T1
- Authority
- AT
- Austria
- Prior art keywords
- mutations
- inflammatory bowel
- provides
- transcription
- octn2
- Prior art date
Links
- 208000022559 Inflammatory bowel disease Diseases 0.000 title abstract 3
- 101000713272 Homo sapiens Solute carrier family 22 member 4 Proteins 0.000 title abstract 2
- 108010038615 Solute Carrier Family 22 Member 5 Proteins 0.000 title abstract 2
- 102100036924 Solute carrier family 22 member 5 Human genes 0.000 title abstract 2
- 102000054765 polymorphisms of proteins Human genes 0.000 title 1
- 208000011231 Crohn disease Diseases 0.000 abstract 4
- 230000035772 mutation Effects 0.000 abstract 4
- 238000013518 transcription Methods 0.000 abstract 3
- 230000035897 transcription Effects 0.000 abstract 3
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108700039691 Genetic Promoter Regions Proteins 0.000 abstract 1
- 108050008339 Heat Shock Transcription Factor Proteins 0.000 abstract 1
- 102000000039 Heat Shock Transcription Factor Human genes 0.000 abstract 1
- 102100032606 Heat shock factor protein 1 Human genes 0.000 abstract 1
- 101710190344 Heat shock factor protein 1 Proteins 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 229940114079 arachidonic acid Drugs 0.000 abstract 1
- 235000021342 arachidonic acid Nutrition 0.000 abstract 1
- 229960004203 carnitine Drugs 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 102000054766 genetic haplotypes Human genes 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000006609 metabolic stress Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002892 organic cations Chemical class 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 239000003440 toxic substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34333801P | 2001-12-21 | 2001-12-21 | |
| US36271702P | 2002-03-08 | 2002-03-08 | |
| US36270002P | 2002-03-08 | 2002-03-08 | |
| US42752902P | 2002-11-19 | 2002-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360030T1 true ATE360030T1 (de) | 2007-05-15 |
Family
ID=32966684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02781695T ATE360030T1 (de) | 2001-12-21 | 2002-12-20 | Polymorphismen der kationentransporter octn1 und octn2 welche mit entzündlichen darmerkrankungen in zusammenhang stehen |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20040197777A1 (de) |
| EP (1) | EP1470156B1 (de) |
| JP (1) | JP2005526491A (de) |
| AT (1) | ATE360030T1 (de) |
| DE (1) | DE60219692T2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1761784B1 (de) * | 2004-05-24 | 2016-10-26 | Universität Zu Köln | Identifizierung des ergothionein-transporters und therapeutische verwendungen davon |
| WO2009114756A2 (en) * | 2008-03-14 | 2009-09-17 | Exagen Diagnostics, Inc. | Biomarkers for inflammatory bowel disease and irritable bowel syndrome |
| KR101741596B1 (ko) | 2014-12-30 | 2017-05-31 | 이화여자대학교 산학협력단 | Octn1 프로모터 내 단일염기다형성 및 이의 용도 |
| JP6513112B2 (ja) * | 2017-02-23 | 2019-05-15 | 本田技研工業株式会社 | 動力伝達装置及び動力伝達装置の潤滑構造 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5219727A (en) * | 1989-08-21 | 1993-06-15 | Hoffmann-Laroche Inc. | Quantitation of nucleic acids using the polymerase chain reaction |
| US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| JP3778545B2 (ja) * | 1997-09-08 | 2006-05-24 | 中外製薬株式会社 | トランスポーター遺伝子 |
| US5969123A (en) * | 1998-03-06 | 1999-10-19 | Millennium Biotherapeutics, Inc. | Nucleic acid molecules derived from a brain tissue library |
| US20030204075A9 (en) * | 1999-08-09 | 2003-10-30 | The Snp Consortium | Identification and mapping of single nucleotide polymorphisms in the human genome |
-
2002
- 2002-12-20 AT AT02781695T patent/ATE360030T1/de not_active IP Right Cessation
- 2002-12-20 JP JP2003554727A patent/JP2005526491A/ja active Pending
- 2002-12-20 EP EP02781695A patent/EP1470156B1/de not_active Expired - Lifetime
- 2002-12-20 US US10/327,188 patent/US20040197777A1/en not_active Abandoned
- 2002-12-20 DE DE60219692T patent/DE60219692T2/de not_active Expired - Fee Related
-
2005
- 2005-12-27 US US11/318,813 patent/US20060105381A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005526491A (ja) | 2005-09-08 |
| EP1470156A2 (de) | 2004-10-27 |
| DE60219692T2 (de) | 2007-12-27 |
| EP1470156B1 (de) | 2007-04-18 |
| DE60219692D1 (de) | 2007-05-31 |
| US20060105381A1 (en) | 2006-05-18 |
| US20040197777A1 (en) | 2004-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |