ATE360680T1 - Universelles, durch licht einschaltbares genpromotorsystem - Google Patents
Universelles, durch licht einschaltbares genpromotorsystemInfo
- Publication number
- ATE360680T1 ATE360680T1 AT02757404T AT02757404T ATE360680T1 AT E360680 T1 ATE360680 T1 AT E360680T1 AT 02757404 T AT02757404 T AT 02757404T AT 02757404 T AT02757404 T AT 02757404T AT E360680 T1 ATE360680 T1 AT E360680T1
- Authority
- AT
- Austria
- Prior art keywords
- phytochrome
- light
- promoter
- activation
- gene
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 108090000679 Phytochrome Proteins 0.000 abstract 4
- 230000004913 activation Effects 0.000 abstract 2
- 230000004568 DNA-binding Effects 0.000 abstract 1
- 108010047161 Plant Photoreceptors Proteins 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000029279 positive regulation of transcription, DNA-dependent Effects 0.000 abstract 1
- 108020001580 protein domains Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000002441 reversible effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Air-Conditioning For Vehicles (AREA)
- Lighting Device Outwards From Vehicle And Optical Signal (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31461501P | 2001-08-23 | 2001-08-23 | |
| US35540202P | 2002-02-06 | 2002-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360680T1 true ATE360680T1 (de) | 2007-05-15 |
Family
ID=26979455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02757404T ATE360680T1 (de) | 2001-08-23 | 2002-08-23 | Universelles, durch licht einschaltbares genpromotorsystem |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6858429B2 (de) |
| EP (1) | EP1434852B1 (de) |
| AT (1) | ATE360680T1 (de) |
| CA (1) | CA2458224A1 (de) |
| DE (1) | DE60219810D1 (de) |
| WO (1) | WO2003018777A1 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002243280A1 (en) * | 2000-10-23 | 2002-06-24 | Engeneos, Inc. | Engineered stimulus-responsive switches |
| US7795397B2 (en) * | 2004-05-06 | 2010-09-14 | The Regents Of The University Of California | Red and near infrared flourescent phyotochrome |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US10052497B2 (en) | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| EP1919497B1 (de) | 2005-07-22 | 2020-02-12 | The Board of Trustees of the Leland Stanford Junior University | Lichtaktivierter kationenkanal und dessen verwendung |
| US9238150B2 (en) | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
| US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US20070136897A1 (en) * | 2005-10-12 | 2007-06-14 | Kim Jeong-Ii | Nucleic acid molecules encoding hyperactive nucleoside di-phosphate kinase 2 and uses thereof |
| US7613574B2 (en) * | 2005-10-28 | 2009-11-03 | S-Matrix | System and method for automating scientific and engineering experimentation for deriving surrogate response data |
| WO2007120989A2 (en) * | 2006-02-24 | 2007-10-25 | Ceres, Inc. | Shade regulatory regions |
| WO2008067089A2 (en) * | 2006-10-27 | 2008-06-05 | Indiana University Research & Technology Corporation | Light-regulated transcription system for use in prokaryotic organisms |
| WO2008086470A1 (en) | 2007-01-10 | 2008-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| DE102007003577A1 (de) | 2007-01-24 | 2008-08-07 | Julius-Maximilians-Universität Würzburg | Zwei-Komponentensystem zur Programmierung bakterieller Membranen |
| WO2008106694A2 (en) | 2007-03-01 | 2008-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Systems, methods and compositions for optical stimulation of target cells |
| US8480662B2 (en) * | 2007-08-22 | 2013-07-09 | Cardiac Pacemakers, Inc. | Systems and devices for photoablation |
| US20090054828A1 (en) * | 2007-08-22 | 2009-02-26 | Cardiac Pacemakers, Inc. | Systems for transient conduction control |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| US10035027B2 (en) | 2007-10-31 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for ultrasonic neuromodulation via stereotactic frame based technique |
| JP5801188B2 (ja) | 2008-04-23 | 2015-10-28 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 標的細胞を光刺激するためのシステム、方法、および組成物 |
| US8828658B2 (en) * | 2008-05-23 | 2014-09-09 | The Regents Of The University Of California | Spatio-temporal control of protein interactions using phytochromes |
| MY162929A (en) | 2008-06-17 | 2017-07-31 | Univ Leland Stanford Junior | Apparatus and methods for controlling cellular development |
| AR072376A1 (es) | 2008-06-27 | 2010-08-25 | Sapphire Energy Inc | Induccion de floculacion en organismos fotosinteticos tales como algas |
| US9101759B2 (en) | 2008-07-08 | 2015-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| US8419145B2 (en) * | 2008-07-25 | 2013-04-16 | Eastman Kodak Company | Inkjet printhead and method of printing with multiple drop volumes |
| NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| WO2011130540A1 (en) * | 2010-04-14 | 2011-10-20 | Duke University | Light stimulated protein interaction molecules and methods of use |
| EP2635111B1 (de) | 2010-11-05 | 2018-05-23 | The Board of Trustees of the Leland Stanford Junior University | Stabilisierte opsin-proteine mit stufenfunktion und verwendungsverfahren dafür |
| CA2816968C (en) | 2010-11-05 | 2019-11-26 | The Board Of Trustees Of The Leland Stanford Junior University | Optically-controlled cns dysfunction |
| CA2816972C (en) | 2010-11-05 | 2019-12-03 | The Board Of Trustees Of The Leland Stanford Junior University | Control and characterization of memory function |
| WO2012061679A2 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| US9522288B2 (en) | 2010-11-05 | 2016-12-20 | The Board Of Trustees Of The Leland Stanford Junior University | Upconversion of light for use in optogenetic methods |
| WO2012061688A1 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of reward-related behaviors |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| CN102643852B (zh) * | 2011-02-28 | 2015-04-08 | 华东理工大学 | 光可控的基因表达系统 |
| US10041057B2 (en) | 2011-07-27 | 2018-08-07 | University Of Wyoming | Near-infrared light-activated proteins |
| DK2737062T3 (en) | 2011-07-27 | 2017-12-04 | Univ Wyoming | NEAR-INFRARED LIGHT-ACTIVATED PROTEINS |
| ES2724803T3 (es) | 2011-12-16 | 2019-09-16 | Univ Leland Stanford Junior | Polipéptidos opsinas y métodos de utilización de los mismos |
| CN104363961B (zh) | 2012-02-21 | 2017-10-03 | 斯坦福大学托管董事会 | 用于治疗盆底神经源性病症的组合物和方法 |
| EP2674497A1 (de) * | 2012-06-12 | 2013-12-18 | Baden-Württemberg Stiftung gGmbH | Lichtreguliertes transgenes Expressionssystem |
| CN103031327B (zh) * | 2012-08-02 | 2015-11-25 | 华东理工大学 | 原核细菌光诱导基因表达系统及其调控基因表达的方法 |
| WO2014121806A1 (en) * | 2013-02-08 | 2014-08-14 | Baden-Württemberg Stiftung Gmbh | System for the caging and controlled release of proteins |
| JP6594854B2 (ja) | 2013-03-15 | 2019-10-23 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 行動状態の光遺伝学的制御方法 |
| JP6549559B2 (ja) * | 2013-04-29 | 2019-07-24 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 標的細胞における活動電位の光遺伝学的調節のための装置、システム及び方法 |
| JP6621747B2 (ja) | 2013-08-14 | 2019-12-18 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 疼痛を制御するための組成物及び方法 |
| US10702581B2 (en) | 2015-05-04 | 2020-07-07 | Ilias Biologics Inc. | Compositions containing protein loaded exosome and methods for preparing and delivering the same |
| KR20160130937A (ko) * | 2015-05-04 | 2016-11-15 | 한국과학기술원 | 목적 단백질을 포함하는 엑소솜의 제조 방법 및 상기 제조 방법에 의해 제조된 엑소솜을 이용하여 목적 단백질을 세포질로 전달시키는 방법 |
| WO2016209654A1 (en) | 2015-06-22 | 2016-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging and/or optogenetic control of light-responsive neurons |
| KR101751917B1 (ko) * | 2016-02-02 | 2017-06-28 | 기초과학연구원 | 가역적으로 활성화 가능한 항체 유사체 및 그의 용도 |
| CN107177629A (zh) * | 2016-03-10 | 2017-09-19 | 华东师范大学 | 一种基因环路远程调控系统进行转基因调控表达的方法 |
| US11859223B2 (en) | 2016-04-07 | 2024-01-02 | The Trustees Of Princeton University | System and method of optogenetically controlling metabolic pathways for the production of chemicals |
| US11294165B2 (en) | 2017-03-30 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modular, electro-optical device for increasing the imaging field of view using time-sequential capture |
| US12054700B2 (en) * | 2019-05-14 | 2024-08-06 | The Regents Of The University Of California | Illumination device for spatial and temporal control of morphogen signaling in cell cultures |
| US12351605B2 (en) | 2020-01-17 | 2025-07-08 | The Johns Hopkins University | Optically controllable FGFR stimulation using wireless controlled cellular lighting system |
| CN112899157A (zh) * | 2020-12-28 | 2021-06-04 | 中国科学院长春应用化学研究所 | 微流控芯片光刺激装置和酵母单细胞光调控基因表达方法及应用 |
| US20240262878A1 (en) | 2021-06-07 | 2024-08-08 | The Board Of Trustees Of The University Of Illinois | Photoactivatable gasdermin proteins |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639952A (en) * | 1989-01-05 | 1997-06-17 | Mycogen Plant Science, Inc. | Dark and light regulated chlorophyll A/B binding protein promoter-regulatory system |
| US5283173A (en) * | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| JP2003524368A (ja) * | 1997-08-26 | 2003-08-19 | アリアド ジーン セラピューティクス インコーポレイテッド | ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、ｄｎａ結合ドメインまたはリガンド結合ドメインを含む融合蛋白 |
| US6251676B1 (en) * | 2000-03-24 | 2001-06-26 | The General Hospital Corporation | Mammalian cell two-hybrid system |
-
2002
- 2002-08-23 AT AT02757404T patent/ATE360680T1/de not_active IP Right Cessation
- 2002-08-23 US US10/227,035 patent/US6858429B2/en not_active Expired - Lifetime
- 2002-08-23 WO PCT/US2002/027216 patent/WO2003018777A1/en not_active Ceased
- 2002-08-23 CA CA002458224A patent/CA2458224A1/en not_active Abandoned
- 2002-08-23 DE DE60219810T patent/DE60219810D1/de not_active Expired - Lifetime
- 2002-08-23 EP EP02757404A patent/EP1434852B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003018777A1 (en) | 2003-03-06 |
| US20030082809A1 (en) | 2003-05-01 |
| CA2458224A1 (en) | 2003-03-06 |
| EP1434852A1 (de) | 2004-07-07 |
| DE60219810D1 (de) | 2007-06-06 |
| EP1434852A4 (de) | 2004-12-22 |
| EP1434852B1 (de) | 2007-04-25 |
| US6858429B2 (en) | 2005-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |