ATE361749T1 - Benzthiazol-3 oxide zur behandlung von proliferativen störungen - Google Patents

Benzthiazol-3 oxide zur behandlung von proliferativen störungen

Info

Publication number: ATE361749T1
Authority: AT; Austria
Prior art keywords: sup; sub; nhr; saturated; ring system
Prior art date: 2003-01-30

Application number

AT04705459T

Other languages

English (en)

Inventor

Campbell Mcinnes

Christopher Meades

Mokdad Mezna

Peter Fischer

Original Assignee

Cyclacel Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-30

Filing date

2004-01-27

Publication date

2007-06-15

2004-01-27 Application filed by Cyclacel Ltd filed Critical Cyclacel Ltd

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE361749T1 publication Critical patent/ATE361749T1/de

Links

230000002062 proliferating effect Effects 0.000 title abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 3
125000005842 heteroatom Chemical group 0.000 abstract 3
229920006395 saturated elastomer Polymers 0.000 abstract 3
-1 COOR<SUP>6</SUP> Chemical group 0.000 abstract 2
125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 2
125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Lubricants (AREA)
Thiazole And Isothizaole Compounds (AREA)

AT04705459T 2003-01-30 2004-01-27 Benzthiazol-3 oxide zur behandlung von proliferativen störungen ATE361749T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0302220.9A GB0302220D0 (en)	2003-01-30	2003-01-30	Use

Publications (1)

Publication Number	Publication Date
ATE361749T1 true ATE361749T1 (de)	2007-06-15

Family

ID=9952174

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04705459T ATE361749T1 (de)	2003-01-30	2004-01-27	Benzthiazol-3 oxide zur behandlung von proliferativen störungen

Country Status (7)

Country	Link
US (1)	US20060040997A1 (de)
EP (1)	EP1589967B1 (de)
JP (1)	JP2006518361A (de)
AT (1)	ATE361749T1 (de)
DE (1)	DE602004006379T2 (de)
GB (1)	GB0302220D0 (de)
WO (1)	WO2004067000A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0012528D0 (en) *	2000-05-23	2000-07-12	Univ Palackeho	Triterpenoid derivatives
GB0219052D0 (en) *	2002-08-15	2002-09-25	Cyclacel Ltd	New puring derivatives
US7245789B2 (en)	2002-10-07	2007-07-17	Vascular Imaging Corporation	Systems and methods for minimally-invasive optical-acoustic imaging
US7504513B2 (en)	2006-02-27	2009-03-17	Hoffman-La Roche Inc.	Thiazolyl-benzimidazoles
US8563542B2 (en)	2007-09-28	2013-10-22	Cyclacel Limited	Pyrimidine derivatives as protein kinase inhibitors
WO2010039950A1 (en)	2008-10-02	2010-04-08	Eberle Michael J	Optical ultrasound receiver
EP2379543A2 (de)	2008-12-18	2011-10-26	F. Hoffmann-La Roche AG	Thiazolyl-benzimidazole
FR2967672B1 (fr) *	2010-11-22	2012-12-28	Sanofi Aventis	Derives de nitrobenzothiazoles, leur preparation et leurs applications therapeutiques
GB201205752D0 (en)	2012-03-30	2012-05-16	Cyclacel Ltd	Treatment
US20170283445A1 (en)	2016-04-05	2017-10-05	University Of South Carolina	Small Molecule Inhibitors Selective For Polo-Like Kinase Proteins
US11162083B2 (en)	2018-06-14	2021-11-02	University Of South Carolina	Peptide based inhibitors of Raf kinase protein dimerization and kinase activity
KR102081417B1 (ko) *	2018-11-23	2020-02-25	주식회사 이뮤니스바이오	Ｂｔｏ―１의 ｎｋ 세포 증식 용도
CA3145286A1 (en)	2019-08-16	2021-02-25	Benjamin Skead	Crystalline forms of pyrimidino diazepine derivative
WO2021032958A1 (en)	2019-08-16	2021-02-25	Cyclacel Limited	Process for the preparation of a pyrimidino-diazepine derivative
US12559733B2 (en)	2020-10-22	2026-02-24	University Of South Carolina	Optimization of type IV BRAF inhibitors for the treatment of melanoma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1904653A1 (de) *	1969-01-31	1970-08-13	Bayer Ag	Substituierte Benzthiazol-N-oxide
DE2013434A1 (en) *	1970-03-20	1971-10-07	Farbenfabriken Bayer Ag, 5090 Lever Kusen	Benzothiazole 3-oxides as concrementinhibitors
DE3835660A1 (de) *	1988-03-25	1989-10-12	Bayer Ag	7-substituierte 2-carbonamido-benzthiazol-3-oxide
EP1100496A4 (de) *	1998-07-21	2002-10-23	Univ Jefferson	Kleine moleküle die bcl-2 proteine hemmen

2003
- 2003-01-30 GB GBGB0302220.9A patent/GB0302220D0/en not_active Ceased
2004
- 2004-01-27 EP EP04705459A patent/EP1589967B1/de not_active Expired - Lifetime
- 2004-01-27 JP JP2006502204A patent/JP2006518361A/ja active Pending
- 2004-01-27 DE DE602004006379T patent/DE602004006379T2/de not_active Expired - Fee Related
- 2004-01-27 AT AT04705459T patent/ATE361749T1/de not_active IP Right Cessation
- 2004-01-27 WO PCT/GB2004/000327 patent/WO2004067000A1/en not_active Ceased
2005
- 2005-07-28 US US11/192,893 patent/US20060040997A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2006518361A (ja)	2006-08-10
DE602004006379D1 (de)	2007-06-21
GB0302220D0 (en)	2003-03-05
DE602004006379T2 (de)	2008-01-10
EP1589967B1 (de)	2007-05-09
WO2004067000A1 (en)	2004-08-12
US20060040997A1 (en)	2006-02-23
EP1589967A1 (de)	2005-11-02

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2007-11-15

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Publication of translation of european patent specification

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2009-10-15

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Ceased due to non-payment of the annual fee