ATE361762T1 - Rekombinante pockenviren des waschbaers und deren verwendung als effektiver impfschutz gegen infektion mit fiv - Google Patents

Rekombinante pockenviren des waschbaers und deren verwendung als effektiver impfschutz gegen infektion mit fiv

Info

Publication number
ATE361762T1
ATE361762T1 AT03013934T AT03013934T ATE361762T1 AT E361762 T1 ATE361762 T1 AT E361762T1 AT 03013934 T AT03013934 T AT 03013934T AT 03013934 T AT03013934 T AT 03013934T AT E361762 T1 ATE361762 T1 AT E361762T1
Authority
AT
Austria
Prior art keywords
fiv
protection against
against infection
effective vaccine
vaccine protection
Prior art date
Application number
AT03013934T
Other languages
English (en)
Inventor
Terri Wasmoen
Hsien-Jue Chu
Lloyd George Chavez
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE361762T1 publication Critical patent/ATE361762T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24041Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/819Viral vaccine for feline species, e.g. cats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03013934T 1995-06-07 1996-06-03 Rekombinante pockenviren des waschbaers und deren verwendung als effektiver impfschutz gegen infektion mit fiv ATE361762T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/482,090 US5820869A (en) 1995-06-07 1995-06-07 Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection

Publications (1)

Publication Number Publication Date
ATE361762T1 true ATE361762T1 (de) 2007-06-15

Family

ID=23914612

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96917038T ATE257015T1 (de) 1995-06-07 1996-06-03 Rekombinante pockenviren des waschbaers sowie ihre verwendung als ein effektiver impfstoff gegen eine infektion mit immunschwaecheviren der katze
AT03013934T ATE361762T1 (de) 1995-06-07 1996-06-03 Rekombinante pockenviren des waschbaers und deren verwendung als effektiver impfschutz gegen infektion mit fiv

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT96917038T ATE257015T1 (de) 1995-06-07 1996-06-03 Rekombinante pockenviren des waschbaers sowie ihre verwendung als ein effektiver impfstoff gegen eine infektion mit immunschwaecheviren der katze

Country Status (16)

Country Link
US (2) US5820869A (de)
EP (2) EP0831921B1 (de)
JP (1) JP4052667B2 (de)
AR (2) AR003425A1 (de)
AT (2) ATE257015T1 (de)
AU (1) AU699794B2 (de)
BR (1) BR9609089A (de)
CA (1) CA2224257C (de)
CO (1) CO4750842A1 (de)
DE (2) DE69631246T2 (de)
DK (1) DK0831921T3 (de)
ES (1) ES2213178T3 (de)
PT (1) PT831921E (de)
SI (1) SI0831921T1 (de)
WO (1) WO1996040268A1 (de)
ZA (1) ZA964694B (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087234B1 (en) 1991-07-09 2006-08-08 Cornell Research Foundation, Inc. Recombinant multivalent viral vaccine
US6254872B1 (en) * 1995-08-25 2001-07-03 University Of Florida Multi-subtype FIV vaccines
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US6106841A (en) * 1998-02-04 2000-08-22 Heska Corporation Delivery method for recombinant raccoon poxvirus
FR2775601B1 (fr) * 1998-03-03 2001-09-21 Merial Sas Vaccins vivants recombines et adjuves
FR2776928B1 (fr) * 1998-04-03 2000-06-23 Merial Sas Vaccins adn adjuves
US7279168B2 (en) 1998-05-01 2007-10-09 Texas A & M University System Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof
CA2327528C (en) * 1998-05-01 2010-10-12 Barbara J. Winslow Recombinant virus expressing foreign dna encoding feline cd80, feline ctla-4 or feline cd86 and uses thereof
US6458528B1 (en) * 1998-05-15 2002-10-01 Idexx Laboratories, Inc. Diagnosis of feline immunodeficiency virus infection using ENV/GAG polypeptide markers
US6641816B1 (en) 1998-06-26 2003-11-04 Aventis Pasteur S.A. Use of poxviruses as enhancer of specific immunity
US6294176B1 (en) * 1998-07-10 2001-09-25 Schering-Plough Veterinary Corp. Recombinant raccoonpox virus and uses thereof as a vaccine in mammalian and avian species
WO2000044935A2 (en) * 1999-01-29 2000-08-03 Bavarian Nordic Research Institute A/S Multiplex real-time pcr
US6497883B1 (en) 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
EP1074625A3 (de) 1999-06-14 2002-01-02 Pfizer Products Inc. DNS impfstoff gegen das immunschwächevirus der Katze
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
MY129765A (en) 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
US20030129161A1 (en) * 2001-09-17 2003-07-10 Hsien-Jue Chu Interleukin-12 as a veterinary vaccine adjuvant
ATE435425T1 (de) * 2003-09-11 2009-07-15 Idexx Lab Inc Verfahren zum nachweis des felinen immunschwächevirus
AU2005267607B8 (en) * 2003-09-11 2009-07-16 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
WO2005062053A2 (en) * 2003-12-18 2005-07-07 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
WO2005080939A2 (en) * 2004-02-19 2005-09-01 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
WO2005123756A1 (en) * 2004-06-21 2005-12-29 University Of Guelph A method of diagnosing fiv
AU2005267605B2 (en) * 2004-06-30 2009-03-26 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
JP4866848B2 (ja) * 2004-06-30 2012-02-01 アイデックス ラボラトリーズ インコーポレイテッド ネコ免疫不全ウイルス(fiv)のenvタンパク質のv3領域に由来するペプチドの使用を含むfivを検出するための方法および装置
US7291338B2 (en) * 2005-03-09 2007-11-06 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
US20080299149A1 (en) * 2007-05-30 2008-12-04 Wyeth Raccoon Poxvirus Expressing Genes of Feline Antigens
WO2011123781A1 (en) 2010-04-02 2011-10-06 Idexx Laboratories, Inc. Detection of feline immunodeficiency virus
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
EP3049106A1 (de) 2013-09-25 2016-08-03 Zoetis Services LLC Divergente impfstoffzusammensetzung gegen pcv2b und verfahren zur verwendung
WO2015077717A1 (en) 2013-11-25 2015-05-28 The Broad Institute Inc. Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
WO2015085147A1 (en) 2013-12-05 2015-06-11 The Broad Institute Inc. Polymorphic gene typing and somatic change detection using sequencing data
KR20230076867A (ko) 2013-12-20 2023-05-31 더 브로드 인스티튜트, 인코퍼레이티드 신생항원 백신과의 병용 요법
US10975442B2 (en) 2014-12-19 2021-04-13 Massachusetts Institute Of Technology Molecular biomarkers for cancer immunotherapy
EP3234130B1 (de) 2014-12-19 2020-11-25 The Broad Institute, Inc. Verfahren zum profiling vom t-zell-rezeptor-repertoire
IL294183B2 (en) 2015-05-20 2023-10-01 Dana Farber Cancer Inst Inc shared neoantigens
TW202241500A (zh) 2015-06-09 2022-11-01 美商博德研究所有限公司 用於贅瘤疫苗之調配物及其製備方法
AU2017254477A1 (en) 2016-04-18 2018-11-01 Jennifer G. ABELIN Improved HLA epitope prediction
US11549149B2 (en) 2017-01-24 2023-01-10 The Broad Institute, Inc. Compositions and methods for detecting a mutant variant of a polynucleotide
WO2020072700A1 (en) 2018-10-02 2020-04-09 Dana-Farber Cancer Institute, Inc. Hla single allele lines
US20220062394A1 (en) 2018-12-17 2022-03-03 The Broad Institute, Inc. Methods for identifying neoantigens
US12394502B2 (en) 2019-10-02 2025-08-19 The General Hospital Corporation Method for predicting HLA-binding peptides using protein structural features
WO2024015892A1 (en) 2022-07-13 2024-01-18 The Broad Institute, Inc. Hla-ii immunopeptidome methods and systems for antigen discovery

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2602478C3 (de) * 1976-01-23 1980-10-09 Behringwerke Ag, 3550 Marburg Impfstoff gegen die Panleukopenie der Feliden
DK507079A (da) * 1978-11-30 1980-05-31 Wellcome Found Svaekket stamme af infektioes katteperitonitisvirus,fremgangsmaade til dens fremstilling og vaccine indeholdende den svaekkedevirusstamme
US5266313A (en) * 1987-02-03 1993-11-30 The United States Of America As Represented By The Department Of Health And Human Services Raccoon poxvirus as a gene expression and vaccine vector for genes of rabies virus and other organisms
US5583112A (en) * 1987-05-29 1996-12-10 Cambridge Biotech Corporation Saponin-antigen conjugates and the use thereof
US5256767A (en) * 1987-06-10 1993-10-26 The Immune Response Corporation Retroviral antigens
CA1341439C (en) * 1987-08-26 2003-09-23 Niels C. Pedersen Feline t-lymphotropic lentivirus
US5118602A (en) * 1987-08-26 1992-06-02 The Regents Of The University Of California Feline T-lymphotropic lentivirus assay
EP0331939B1 (de) * 1988-02-16 2001-11-14 Greatbatch Gen-Aid, Ltd Modifizierte Zellen mit Resistenz gegen Retroviralinfektionen
US5324664A (en) * 1988-08-08 1994-06-28 The Upjohn Company Herpes virus thymidien kinase-encoding DNA
US5219725A (en) * 1988-12-05 1993-06-15 Idexx Laboratories Incorporated Monoclonal antibodies to feline-t-lymphotropic lentivirus
US5177014A (en) * 1988-12-05 1993-01-05 Idexx Laboratories, Inc. Monoclonal antibodies to feline-T-lymphotropic lentivirus
JP3058685B2 (ja) * 1989-05-08 2000-07-04 アイデックス ラボラトリーズ インコーポレーテッド ネコt細胞リンパトロピック レンチウィルスのポリペプチド
US5252348A (en) * 1990-10-19 1993-10-12 Univ. Of Florida Research Foundation, Inc. Artificial viral envelopes
US5242686A (en) * 1990-11-07 1993-09-07 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
FR2669338A1 (fr) * 1990-11-21 1992-05-22 Centre Nat Rech Scient Fragments peptidiques issus de la proteine externe du vif, anticorps antifragments, application de ceux-ci au diagnostic et/ou au traitement de l'immunodeficience feline.
US6228608B1 (en) * 1991-02-28 2001-05-08 Aquila Biopharmaceuticals, Inc. Recombinant FIV glycoprotein 160 and P24 gag protein
AU2299892A (en) * 1991-07-05 1993-02-11 Regents Of The University Of California, The Feline lymphoid cell lines capable of producing fiv
US5413927A (en) * 1991-09-03 1995-05-09 North Carolina State University Feline immunodeficiency virus isolate NCSU1Lb
WO1993008836A1 (en) * 1991-10-28 1993-05-13 Institut Pasteur Induction of protection against viral infection by synergy between viral proteins and viral peptides
DK0584348T3 (da) * 1992-03-11 2005-09-19 Powderject Vaccines Inc Genetisk vaccine mod immundefektvirusser
ATE278018T1 (de) * 1992-06-16 2004-10-15 Centre Nat Rech Scient Nukleotid- und peptidsequenzen des immunschwächevirus der katze, isolat wo und anwendungen der sequenzen in der diagnostik und zur verhinderung der infektion
EP0576092B1 (de) * 1992-06-26 2002-10-16 Akzo Nobel N.V. Rekombinanter Katzen-Herpesvirus-Impfstoff
GB9215233D0 (en) * 1992-07-17 1992-09-02 Pitman Moore Inc Vaccines
GB9215232D0 (en) * 1992-07-17 1992-09-02 Pitman Moore Inc Vaccines
GB9219936D0 (en) * 1992-09-21 1992-11-04 Pitman Moore Inc Vaccines
CA2142325A1 (en) * 1992-09-21 1994-03-31 William T. L. Lee Recombinant retroviral vector against felv and/or fiv
WO1994020622A1 (en) * 1993-03-11 1994-09-15 Akzo Nobel N.V. Polypeptide fragment capable of inducing neutralising antibodies against feline immuno-deficiency virus
TW377373B (en) * 1993-09-22 1999-12-21 Wyeth Corp Recombinant raccoon pox viruses and their use as an effective vaccine against feline infectious peritonitis virus disease

Also Published As

Publication number Publication date
AR042378A2 (es) 2005-06-22
EP1374910B1 (de) 2007-05-09
DE69631246T2 (de) 2004-11-25
US5820869A (en) 1998-10-13
US5989562A (en) 1999-11-23
AU699794B2 (en) 1998-12-17
AU5973196A (en) 1996-12-30
ZA964694B (en) 1997-12-05
JP4052667B2 (ja) 2008-02-27
CA2224257A1 (en) 1996-12-19
EP0831921A1 (de) 1998-04-01
DE69637080D1 (de) 2007-06-21
EP0831921B1 (de) 2004-01-02
EP1374910A1 (de) 2004-01-02
CO4750842A1 (es) 1999-03-31
HK1008982A1 (en) 1999-05-21
CA2224257C (en) 2005-08-16
DE69637080T2 (de) 2008-01-10
ATE257015T1 (de) 2004-01-15
SI0831921T1 (en) 2004-06-30
PT831921E (pt) 2004-05-31
WO1996040268A1 (en) 1996-12-19
JPH11506614A (ja) 1999-06-15
ES2213178T3 (es) 2004-08-16
HK1060847A1 (en) 2004-08-27
AR003425A1 (es) 1998-08-05
BR9609089A (pt) 1999-02-02
DK0831921T3 (da) 2004-04-26
DE69631246D1 (de) 2004-02-05

Similar Documents

Publication Publication Date Title
ATE361762T1 (de) Rekombinante pockenviren des waschbaers und deren verwendung als effektiver impfschutz gegen infektion mit fiv
FI933145L (fi) Hyönteiskarkotteella ja -suojalla varustettu kangas
ITRM940587A0 (it) Composizione insetticida e repellente per gli insetti
DE69716429D1 (de) Insektenabwehrendes sonnenschutzmittel
DE69310525D1 (de) Schutz gegen leberschäden mit hgf
DE69632568D1 (de) Intramuskuläre Stimulationsleitung mit verstärkten Abwehreigenschaften gegen Infektionen
DE69619745D1 (de) Nadelschutzvorrichtung mit auslösbarem Verschluss
GR1002767B (el) Αντιπαρασιτικη συνθεση για την θεραπεια και την προστασια των ζωων συντροφιας.
FI941270L (fi) Kiinteä UV-suoja-aine, sen valmistus ja käytt¦
DE69228492D1 (de) 3,4,N-Trisubstituierte-4,5-dihydro-1H-Pyrazol-1-carboxamide und deren Anwendung als Insektizide
DE69431965D1 (de) Wirkstoff gegen fettsucht
DE69729449D1 (de) Rekombinante alpha-2,3-sialyltransferasen und deren verwendung
NZ310055A (en) Genetically altered feline immunodeficiency viruses and their use as an effective vaccine against feline immunodeficiency virus infection
DE69322280D1 (de) Therapeutisches agenz aus mycobacterium vaccae und seine verwendung gegen eine hiv-infektion mit aids
ATE227117T1 (de) Sonnenschutzformulierungen mit wirkung gegen herpes simplex viren
FI940139A7 (fi) Alkenyyliryhmiä sisältäviä siloksaanikopolymeerejä, niiden valmistus ja käyttö
FI934221A7 (fi) Piperidiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI945177L (fi) Vinyylioksiryhmiä sisältävät siloksaanisekapolymeerit, niiden valmistus ja käyttö
DE69420985D1 (de) Gegen Wärmestrahlung schützendes Material
ATE316793T1 (de) Stimulierung wirtseigener abwehrmechanismen gegen virusangriffe
FI915850A7 (fi) Verkkoutuvia, fluoripitoisia kopolymeerejä ja näihin kopolymeereihin perustuvia lakkoja
DE69330385D1 (de) Schützende antigene gegen eine (echinococcus granulosus) infektion und impfstoffe die entsprechende antigene enthalten
NO973230D0 (no) Nye peptider, deres fremstilling og anvendelse
FI945178A7 (fi) Vinyylioksiryhmiä sisältävät siloksaanikopolymeerit, niiden valmistus ja käyttö
DE68927340D1 (de) Biologischer impfstoff, wirksam gegen aphanomyces

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties