ATE361982T1 - Enon reduktase gen und mikrobielle herstellung von levodion - Google Patents
Enon reduktase gen und mikrobielle herstellung von levodionInfo
- Publication number
- ATE361982T1 ATE361982T1 AT03757875T AT03757875T ATE361982T1 AT E361982 T1 ATE361982 T1 AT E361982T1 AT 03757875 T AT03757875 T AT 03757875T AT 03757875 T AT03757875 T AT 03757875T AT E361982 T1 ATE361982 T1 AT E361982T1
- Authority
- AT
- Austria
- Prior art keywords
- levodion
- enon
- reductase gene
- microbial production
- enzyme
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 2
- ACFIXJIJDZMPPO-NNYOXOHSSA-N NADPH Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](OP(O)(O)=O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 ACFIXJIJDZMPPO-NNYOXOHSSA-N 0.000 abstract 1
- 102000004316 Oxidoreductases Human genes 0.000 abstract 1
- 108090000854 Oxidoreductases Proteins 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02021098 | 2002-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE361982T1 true ATE361982T1 (de) | 2007-06-15 |
Family
ID=32010922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03757875T ATE361982T1 (de) | 2002-09-23 | 2003-09-19 | Enon reduktase gen und mikrobielle herstellung von levodion |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7592166B2 (de) |
| EP (1) | EP1543125B1 (de) |
| JP (1) | JP2006500018A (de) |
| CN (1) | CN100584949C (de) |
| AT (1) | ATE361982T1 (de) |
| AU (1) | AU2003273910A1 (de) |
| DE (1) | DE60313784D1 (de) |
| WO (1) | WO2004027065A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7818372B1 (en) * | 2008-01-16 | 2010-10-19 | Sprint Communications Company L.P. | Web portal framework for open innovation |
| TW201000635A (en) * | 2008-05-20 | 2010-01-01 | Dsm Ip Assets Bv | Preparation of epsilon-caprolactam from (Z)-6,7-dihydro-1H-azepin-2(5H)-one |
| EP2123767A1 (de) * | 2008-05-20 | 2009-11-25 | DSM IP Assets B.V. | Herstellung von Epsilon-Caprolactam mittels Lysinzyklisierung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4095038A (en) * | 1974-08-21 | 1978-06-13 | Hoffmann-La Roche Inc. | Optically active cyclohexane derivatives |
| CA2315837A1 (en) * | 1999-08-02 | 2001-02-02 | F. Hoffmann-La Roche Ag | Microbial production of levodione |
| JP4688313B2 (ja) | 2001-02-23 | 2011-05-25 | ダイセル化学工業株式会社 | 新規なエノン還元酵素、その製造方法、およびこれを利用したα，β−不飽和ケトンの炭素−炭素２重結合を選択的に還元する方法 |
| CN1639347A (zh) | 2002-02-22 | 2005-07-13 | Dsmip资产公司 | 生产左旋二酮的方法 |
| AU2003210271A1 (en) | 2002-02-22 | 2003-09-09 | Dsm Ip Assets B.V. | Enone reductase |
-
2003
- 2003-09-19 US US10/528,960 patent/US7592166B2/en not_active Expired - Fee Related
- 2003-09-19 EP EP03757875A patent/EP1543125B1/de not_active Expired - Lifetime
- 2003-09-19 DE DE60313784T patent/DE60313784D1/de not_active Expired - Lifetime
- 2003-09-19 AU AU2003273910A patent/AU2003273910A1/en not_active Abandoned
- 2003-09-19 CN CN03822613A patent/CN100584949C/zh not_active Expired - Fee Related
- 2003-09-19 AT AT03757875T patent/ATE361982T1/de not_active IP Right Cessation
- 2003-09-19 JP JP2004537136A patent/JP2006500018A/ja active Pending
- 2003-09-19 WO PCT/EP2003/010473 patent/WO2004027065A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006500018A (ja) | 2006-01-05 |
| DE60313784D1 (de) | 2007-06-21 |
| CN100584949C (zh) | 2010-01-27 |
| US20060128000A1 (en) | 2006-06-15 |
| CN1751123A (zh) | 2006-03-22 |
| EP1543125A2 (de) | 2005-06-22 |
| WO2004027065A2 (en) | 2004-04-01 |
| EP1543125B1 (de) | 2007-05-09 |
| US7592166B2 (en) | 2009-09-22 |
| WO2004027065A3 (en) | 2004-05-27 |
| AU2003273910A1 (en) | 2004-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |