ATE362397T1 - Matricen mit speichern und verwendungen davon - Google Patents

Matricen mit speichern und verwendungen davon

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Publication number
ATE362397T1
ATE362397T1 AT96934064T AT96934064T ATE362397T1 AT E362397 T1 ATE362397 T1 AT E362397T1 AT 96934064 T AT96934064 T AT 96934064T AT 96934064 T AT96934064 T AT 96934064T AT E362397 T1 ATE362397 T1 AT E362397T1
Authority
AT
Austria
Prior art keywords
memories
matrix
materials
combinations
matrix materials
Prior art date
Application number
AT96934064T
Other languages
English (en)
Inventor
Michael Nova
Hanan Potash
Xioa-Yi Xiao
Bradley Sargent
Zahra Parandoosh
Gary David
Original Assignee
Discovery Partners Internation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/538,387 external-priority patent/US5874214A/en
Priority claimed from US08/567,746 external-priority patent/US6025129A/en
Priority claimed from US08/633,410 external-priority patent/US6100026A/en
Priority claimed from US08/669,252 external-priority patent/US6319668B1/en
Priority claimed from US08/711,426 external-priority patent/US6284459B1/en
Priority claimed from US08/709,435 external-priority patent/US6017496A/en
Application filed by Discovery Partners Internation filed Critical Discovery Partners Internation
Application granted granted Critical
Publication of ATE362397T1 publication Critical patent/ATE362397T1/de

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    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
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    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00782—Type of codes reprogrammmable code
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/02—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change
    • G11C13/025—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change using fullerenes, e.g. C60, or nanotubes, e.g. carbon or silicon nanotubes

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  • Biochemistry (AREA)
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  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
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  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Indole Compounds (AREA)
  • Air Bags (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
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AT96934064T 1995-10-03 1996-10-03 Matricen mit speichern und verwendungen davon ATE362397T1 (de)

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US08/538,387 US5874214A (en) 1995-04-25 1995-10-03 Remotely programmable matrices with memories
US08/567,746 US6025129A (en) 1995-04-25 1995-12-05 Remotely programmable matrices with memories and uses thereof
US63981396A 1996-04-02 1996-04-02
US08/633,410 US6100026A (en) 1995-04-25 1996-06-10 Matrices with memories and uses thereof
US08/669,252 US6319668B1 (en) 1995-04-25 1996-06-24 Method for tagging and screening molecules
US08/711,426 US6284459B1 (en) 1995-04-25 1996-09-05 Solid support matrices with memories and combinatorial libraries therefrom
US08/709,435 US6017496A (en) 1995-06-07 1996-09-06 Matrices with memories and uses thereof
US08/723,423 US5961923A (en) 1995-04-25 1996-09-30 Matrices with memories and uses thereof

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Families Citing this family (282)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287850B1 (en) 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
US6256643B1 (en) * 1998-03-10 2001-07-03 Baxter International Inc. Systems and methods for storing, retrieving, and manipulating data in medical processing devices
US5925562A (en) * 1995-04-25 1999-07-20 Irori Remotely programmable matrices with memories
CN1181720A (zh) 1995-04-25 1998-05-13 伊萝莉公司 可远程编程的存储器材料及其应用
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US6319668B1 (en) 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
US6352854B1 (en) 1995-04-25 2002-03-05 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6340588B1 (en) 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US5704910A (en) 1995-06-05 1998-01-06 Nephros Therapeutics, Inc. Implantable device and use therefor
US6720149B1 (en) * 1995-06-07 2004-04-13 Affymetrix, Inc. Methods for concurrently processing multiple biological chip assays
US20030203390A1 (en) * 1995-10-26 2003-10-30 Kaye Paul H. Coded particles for process sequence tracking in combinatorial compound library preparation
US6001571A (en) 1995-11-30 1999-12-14 Mandecki; Wlodek Multiplex assay for nucleic acids employing transponders
US5641634A (en) 1995-11-30 1997-06-24 Mandecki; Wlodek Electronically-indexed solid-phase assay for biomolecules
AU1061997A (en) 1995-11-30 1997-06-19 Wlodek Mandecki Screening of drugs from chemical combinatorial libraries employing transponders
US6215401B1 (en) * 1996-03-25 2001-04-10 Intermec Ip Corp. Non-laminated coating for radio frequency transponder (RF tag)
US7144119B2 (en) * 1996-04-25 2006-12-05 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US7041510B2 (en) 1996-04-25 2006-05-09 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US6387707B1 (en) * 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
US6251691B1 (en) 1996-04-25 2001-06-26 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US6958245B2 (en) 1996-04-25 2005-10-25 Bioarray Solutions Ltd. Array cytometry
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
WO1998015825A2 (en) * 1996-10-07 1998-04-16 Irori Matrices with memories in automated drug discovery and units therefor
IL156002A0 (en) 1997-02-12 2003-12-23 Eugene Y Chan Methods and products for analyzing polymers
US6023540A (en) * 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US7622294B2 (en) 1997-03-14 2009-11-24 Trustees Of Tufts College Methods for detecting target analytes and enzymatic reactions
US20030027126A1 (en) 1997-03-14 2003-02-06 Walt David R. Methods for detecting target analytes and enzymatic reactions
US20020119580A1 (en) * 1997-04-17 2002-08-29 Corless Anthony Robert Radiofrequency encoded chemical library synthesis particles method
GB2337268B (en) * 1997-04-17 2002-10-09 Zeneca Ltd Radiofrequency encoded chemical library synthesis particles
NL1005914C2 (nl) * 1997-04-28 1998-10-29 Sgt Exploitatie Bv Inrichting voor het opslaan en/of behandelen van chemicaliën.
DE69838067T2 (de) * 1997-05-23 2008-03-13 Bioarray Solutions Ltd. Farbkodierung und in situ abfrage von matrix-gekoppelten chemischen verbindungen
US20020084329A1 (en) * 1997-07-16 2002-07-04 Kaye Paul H. Coded items for labeling objects
US7068830B2 (en) * 1997-07-25 2006-06-27 Affymetrix, Inc. Method and system for providing a probe array chip design database
US6484183B1 (en) * 1997-07-25 2002-11-19 Affymetrix, Inc. Method and system for providing a polymorphism database
US6826296B2 (en) 1997-07-25 2004-11-30 Affymetrix, Inc. Method and system for providing a probe array chip design database
US6420108B2 (en) * 1998-02-09 2002-07-16 Affymetrix, Inc. Computer-aided display for comparative gene expression
EP1002297A1 (de) * 1997-08-07 2000-05-24 Imaging Research, Inc. Digitales bilderzeugungssystem für testverfahren in mehrlochplatten, gelen und bloten
US6093574A (en) * 1997-08-11 2000-07-25 Ventana Medical Systems Method and apparatus for rinsing a microscope slide
JP3719932B2 (ja) * 1997-08-18 2005-11-24 アメルシャム・パブリック・リミテッド・カンパニー シンチレーションプロキシミティー試験
US5961925A (en) * 1997-09-22 1999-10-05 Bristol-Myers Squibb Company Apparatus for synthesis of multiple organic compounds with pinch valve block
US6117643A (en) * 1997-11-25 2000-09-12 Ut Battelle, Llc Bioluminescent bioreporter integrated circuit
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
AU761085B2 (en) * 1998-03-07 2003-05-29 Claus-Frenz Claussen Method and device for evaluating an kinetic pattern
GB9809265D0 (en) * 1998-05-01 1998-07-01 Central Research Lab Ltd Apparatus for locating a plurality of articles
US6872535B2 (en) * 1998-05-20 2005-03-29 Aventis Pharmaceuticals Inc. Three-dimensional array of supports for solid-phase parallel synthesis and method of use
US6171870B1 (en) * 1998-08-06 2001-01-09 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6185561B1 (en) 1998-09-17 2001-02-06 Affymetrix, Inc. Method and apparatus for providing and expression data mining database
GB9820163D0 (en) * 1998-09-17 1998-11-11 Sentec Ltd Micro-fabricated coded labels, reading systems and their applications
US20040199544A1 (en) * 2000-11-02 2004-10-07 Affymetrix, Inc. Method and apparatus for providing an expression data mining database
GB9822436D0 (en) * 1998-10-14 1998-12-09 Cambridge Combinatorial Ltd Sintered/co-sintered materials
US6908737B2 (en) * 1999-04-15 2005-06-21 Vitra Bioscience, Inc. Systems and methods of conducting multiplexed experiments
US7253435B2 (en) * 1999-04-15 2007-08-07 Millipore Corporation Particles with light-polarizing codes
US20030207249A1 (en) * 1999-04-15 2003-11-06 Beske Oren E. Connection of cells to substrates using association pairs
US20030166015A1 (en) * 1999-04-15 2003-09-04 Zarowitz Michael A. Multiplexed analysis of cell-substrate interactions
US20030129654A1 (en) * 1999-04-15 2003-07-10 Ilya Ravkin Coded particles for multiplexed analysis of biological samples
US20030134330A1 (en) * 1999-04-15 2003-07-17 Ilya Ravkin Chemical-library composition and method
AU4245900A (en) * 1999-04-15 2000-11-02 Virtual Arrays, Inc. Combinatorial chemical library supports having indicia at coding positions and methods of use
AU771517B2 (en) 1999-04-16 2004-03-25 Mycartis Nv Encoding of microcarriers
CA2406572A1 (en) * 1999-04-23 2000-11-02 Monica Palacios-Boyce Microelectromechanical devices useful for manipulating cells or embryos, kits thereof, methods of making same, and methods of use thereof
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
US7179638B2 (en) 1999-07-30 2007-02-20 Large Scale Biology Corporation Microarrays and their manufacture by slicing
US6653151B2 (en) 1999-07-30 2003-11-25 Large Scale Proteomics Corporation Dry deposition of materials for microarrays using matrix displacement
US6713309B1 (en) 1999-07-30 2004-03-30 Large Scale Proteomics Corporation Microarrays and their manufacture
WO2001056636A1 (de) * 2000-02-01 2001-08-09 Disetronic Licensing Ag Konfigurierbare vorrichtung und verfahren zur abgabe einer substanz
WO2001059159A2 (en) * 2000-02-10 2001-08-16 Instastain Molecular biological kit apparatus and method
AU2001241668A1 (en) * 2000-02-23 2001-09-03 Xenoport, Inc. Self-encoded combinatorial synthesis of compound multiplets
US7102024B1 (en) 2000-08-01 2006-09-05 Schwartz David A Functional biopolymer modification reagents and uses thereof
US6686461B1 (en) 2000-03-22 2004-02-03 Solulink Bioscience, Inc. Triphosphate oligonucleotide modification reagents and uses thereof
US7216113B1 (en) * 2000-03-24 2007-05-08 Symyx Technologies, Inc. Remote Execution of Materials Library Designs
GB0008392D0 (en) * 2000-04-05 2000-05-24 Unilever Plc Process for the production of a deodorant or antiperspirant product
US6432365B1 (en) 2000-04-14 2002-08-13 Discovery Partners International, Inc. System and method for dispensing solution to a multi-well container
US6824738B1 (en) 2000-04-14 2004-11-30 Discovery Partners International, Inc. System and method for treatment of samples on solid supports
US6503457B1 (en) 2000-04-14 2003-01-07 Discovery Partners International, Inc. Container and method for high volume treatment of samples on solid supports
GB0009719D0 (en) * 2000-04-19 2000-06-07 Scient Generics Ltd A method of fabricating coded particles
AU2001261116A1 (en) * 2000-05-03 2001-11-12 Charles Pidgeon Method and compositions for drug discovery
WO2001085325A2 (en) * 2000-05-05 2001-11-15 Palti Yoram Prof Parallel chemical reactor
US7396675B2 (en) * 2000-06-02 2008-07-08 Bayer Technology Services Gmbh Kit and method for determining a plurality of analytes
GB0013619D0 (en) * 2000-06-06 2000-07-26 Glaxo Group Ltd Sample container
DE10028875A1 (de) * 2000-06-10 2001-12-20 Hte Gmbh Rechnergestützte Optimierung von Substanzbibliotheken
US6347650B1 (en) 2000-06-16 2002-02-19 Discovery Partners International, Inc. Device and method for dispensing particulate material
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
AU7299301A (en) 2000-06-21 2002-01-02 Bioarray Solutions Ltd Multianalyte molecular analysis using application-specific random particle arrays
EP2100971A3 (de) * 2000-07-07 2009-11-25 Visigen Biotechnologies, Inc. Echtzeit-Sequenzbestimmung
EP1304417A4 (de) * 2000-07-21 2009-09-02 Hitachi Construction Machinery Vorrichtung zur übertragung von daten für eine baumaschine
CH694935A5 (de) * 2000-07-26 2005-09-30 Straumann Holding Ag Oberflaechenmodifizierte Implantate.
WO2002021428A1 (en) * 2000-09-01 2002-03-14 Large Scale Proteomics Corporation Reference database
US6539102B1 (en) 2000-09-01 2003-03-25 Large Scale Proteomics Reference database
US6980674B2 (en) * 2000-09-01 2005-12-27 Large Scale Proteomics Corp. Reference database
US7785810B2 (en) * 2000-09-09 2010-08-31 The Research Foundation Of State University Of New York Method and compositions for isolating metastatic cancer cells, and use in measuring metastatic potential of a cancer thereof
US7057704B2 (en) * 2000-09-17 2006-06-06 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US6910044B2 (en) * 2000-09-20 2005-06-21 Sap Aktiengesellschaft Method and apparatus for structuring, maintaining, and using families of data
US20030045005A1 (en) * 2000-10-17 2003-03-06 Michael Seul Light-controlled electrokinetic assembly of particles near surfaces
GB2384777B (en) * 2000-10-18 2005-03-02 Virtual Arrays Inc Multiplexed cell analysis system
JP2004537712A (ja) * 2000-10-18 2004-12-16 バーチャル・アレイズ・インコーポレーテッド 多重細胞分析システム
US6826487B1 (en) * 2000-10-25 2004-11-30 General Electric Company Method for defining an experimental space and method and system for conducting combinatorial high throughput screening of mixtures
DE10054055A1 (de) * 2000-10-31 2002-05-23 Nmi Univ Tuebingen Verfahren zur Analyse von Proteinen
EP1341475A1 (de) * 2000-12-01 2003-09-10 Nephros Therapeutics, Inc. Gerät zur konditionierung von intravaskulärem blut
US7211414B2 (en) 2000-12-01 2007-05-01 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US20030009293A1 (en) * 2001-01-09 2003-01-09 Anderson Norman G. Reference database
ATE359512T1 (de) * 2001-02-13 2007-05-15 Pronostics Ltd Biochemisches verfahren und vorrichtung zur bestimmung von eigenschaften von proteinen
DE10117274B4 (de) * 2001-04-06 2005-03-03 Hte Ag The High Throughput Experimentation Company Verfahren zur Analyse und Archivierung von wenigstens einer Materialbibliothek
US20030211464A1 (en) * 2001-05-02 2003-11-13 Charles Pidgeon Method and compositions for drug discovery
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US7668697B2 (en) 2006-02-06 2010-02-23 Andrei Volkov Method for analyzing dynamic detectable events at the single molecule level
JP3935487B2 (ja) 2001-07-16 2007-06-20 フーベルト・ケスター 捕獲化合物、その収集物、ならびにプロテオームおよび複合組成物の分析方法
US20030143612A1 (en) * 2001-07-18 2003-07-31 Pointilliste, Inc. Collections of binding proteins and tags and uses thereof for nested sorting and high throughput screening
US20050043421A1 (en) * 2001-08-29 2005-02-24 Van Der Wal Hanno R Process to manufacture polyurethane products using polymer polyols in which the carrier polyol is a tertiary amone based polyol
ES2712173T3 (es) 2001-10-15 2019-05-09 Bioarray Solutions Ltd Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas
US20030219800A1 (en) * 2001-10-18 2003-11-27 Beske Oren E. Multiplexed cell transfection using coded carriers
US20080187949A1 (en) * 2001-10-26 2008-08-07 Millipore Corporation Multiplexed assays of cell migration
AU2002363076A1 (en) * 2001-10-26 2003-05-06 Virtual Arrays, Inc. Assay systems with adjustable fluid communication
JP2005514603A (ja) * 2001-11-06 2005-05-19 アジリックス・コーポレイション 高感度コード化検出システム
US7335153B2 (en) * 2001-12-28 2008-02-26 Bio Array Solutions Ltd. Arrays of microparticles and methods of preparation thereof
EP1474504A2 (de) * 2002-01-24 2004-11-10 Pointilliste, Inc. Verwendung von sammlungen von bindungsstellen für die probenprofilierung und andere anwendungen
US8775196B2 (en) 2002-01-29 2014-07-08 Baxter International Inc. System and method for notification and escalation of medical data
US10173008B2 (en) 2002-01-29 2019-01-08 Baxter International Inc. System and method for communicating with a dialysis machine through a network
ES2319634T3 (es) * 2002-03-11 2009-05-11 Caprotec Bioanalytics Gmbh Compuestos y metodos para analizar el proteoma.
US20030177380A1 (en) * 2002-03-18 2003-09-18 Woods Stanley P. Devices for storing array data and methods of using the same
US8234128B2 (en) 2002-04-30 2012-07-31 Baxter International, Inc. System and method for verifying medical device operational parameters
US7460960B2 (en) * 2002-05-10 2008-12-02 Epitome Biosystems, Inc. Proteome epitope tags and methods of use thereof in protein modification analysis
US7618788B2 (en) * 2002-05-10 2009-11-17 Millipore Corporation Proteome epitope tags and methods of use thereof in protein modification analysis
EP1532439A4 (de) * 2002-05-10 2006-10-18 Epitome Biosystems Inc Unverwechselbare erkennungssequenzen und deren verwendung in der proteinanalyse
US20040126773A1 (en) * 2002-05-23 2004-07-01 Beske Oren E. Assays with coded sensor particles to sense assay conditions
US20030236759A1 (en) * 2002-06-21 2003-12-25 Tsung-Hsuan Ho Neural network for determining the endpoint in a process
US7619819B2 (en) 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
AU2003270726A1 (en) 2002-09-12 2004-04-30 Cidra Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
EP1575707A1 (de) 2002-09-12 2005-09-21 Cyvera Corporation Verfahren und vorrichtung zur ausrichtung von länglichen mikroperlen zu deren untersuchung
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
US20080207465A1 (en) * 2002-10-28 2008-08-28 Millipore Corporation Assay systems with adjustable fluid communication
CA2504443A1 (en) * 2002-10-30 2004-05-13 Pointilliste, Inc. Methods for producing polypeptide-tagged collections and capture systems containing the tagged polypeptides
US20040096986A1 (en) * 2002-11-13 2004-05-20 Klein Kenneth J. Pharmaceutical combi-chem purification factory system
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US20040115794A1 (en) * 2002-12-12 2004-06-17 Affymetrix, Inc. Methods for detecting transcriptional factor binding sites
EP1583972B1 (de) * 2003-01-16 2010-11-24 caprotec bioanalytics GmbH Verfahren zur identifizierung von auf arzneimittel nicht-zielgerichteten proteinen
US8081792B2 (en) 2003-08-20 2011-12-20 Illumina, Inc. Fourier scattering methods for encoding microbeads and methods and apparatus for reading the same
WO2004071641A2 (en) * 2003-02-10 2004-08-26 Pointilliste, Inc. Self-assembling arrays and uses thereof
US7179596B2 (en) * 2003-02-17 2007-02-20 Sceptor Industries, Inc. Biological particulate matter analogue
GB0306914D0 (en) * 2003-03-26 2003-04-30 Millennium Pharm Inc Solid support devices
US20040235056A1 (en) * 2003-05-07 2004-11-25 Mallouk Thomas E. Method of assembling particle libraries
US20040241659A1 (en) * 2003-05-30 2004-12-02 Applera Corporation Apparatus and method for hybridization and SPR detection
US7556660B2 (en) * 2003-06-11 2009-07-07 James Kevin Shurtleff Apparatus and system for promoting a substantially complete reaction of an anhydrous hydride reactant
US8719053B2 (en) 2003-07-17 2014-05-06 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
US7860727B2 (en) 2003-07-17 2010-12-28 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
PT1662987E (pt) 2003-09-11 2012-02-14 Theranos Inc Dispositivo médico para monitorização de analito e distribuição de droga
US7488451B2 (en) * 2003-09-15 2009-02-10 Millipore Corporation Systems for particle manipulation
EP1676133A4 (de) * 2003-09-15 2008-05-21 Millipore Corp Tests mit primärzellen
WO2005029705A2 (en) 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
PT1664722E (pt) 2003-09-22 2011-12-28 Bioarray Solutions Ltd Polielectrólito imobilizado à superfície com grupos funcionais múltiplos capazes de se ligarem covalentemente às biomoléculas
US7858108B2 (en) * 2003-10-21 2010-12-28 Richard Nagler Elutable surface coating
US20110165244A1 (en) * 2003-10-21 2011-07-07 Allvivo Vascular, Inc. Bioresponsive polymer formulations for delivery of bioactive agents
EP1692298A4 (de) 2003-10-28 2008-08-13 Bioarray Solutions Ltd Optimierung der genexpressionsanalyse unter verwendung immobilisierter fängersonden
WO2005045060A2 (en) 2003-10-29 2005-05-19 Bioarray Solutions, Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
WO2005050224A2 (en) * 2003-11-13 2005-06-02 Epitome Biosystems Inc. Small molecule and peptide arrays and uses thereof
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
DE102004026240B4 (de) * 2004-05-25 2007-10-04 Eppendorf Ag Mikrotiterplatte und Verfahren zum Herstellen einer Mikrotiterplatte
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
US7315019B2 (en) * 2004-09-17 2008-01-01 Pacific Biosciences Of California, Inc. Arrays of optical confinements and uses thereof
US8015725B2 (en) * 2004-09-21 2011-09-13 Dos-I Solutions, S.L. Method and machine for the sintering and/or drying of powder materials using infrared radiation
US7602952B2 (en) 2004-11-16 2009-10-13 Illumina, Inc. Scanner having spatial light modulator
US7604173B2 (en) 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
US20060205015A1 (en) * 2005-02-14 2006-09-14 Herve Ansanay Method for detecting the interactions between a G protein-coupled receptor (GPCR) and one of the Galpha or Gbetagamma subunits
MX2007013985A (es) * 2005-05-09 2008-02-22 Theranos Inc Sistemas de fluidos de punto de cuidado y usos de los mismos.
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
US8784336B2 (en) 2005-08-24 2014-07-22 C. R. Bard, Inc. Stylet apparatuses and methods of manufacture
JP2009516313A (ja) * 2005-11-11 2009-04-16 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 走査装置において情報キャリアを位置合わせするシステム及び方法
US7623624B2 (en) 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
JP4933563B2 (ja) 2005-12-19 2012-05-16 ヴェンタナ メディカル システムズ， インコーポレイテッド 解剖病理学における自動リーンメソッド
US8048419B2 (en) 2006-02-02 2011-11-01 Innovative Biotherapies, Inc. Extracorporeal cell-based therapeutic device and delivery system
US7855057B2 (en) * 2006-03-23 2010-12-21 Millipore Corporation Protein splice variant/isoform discrimination and quantitative measurements thereof
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US20080107739A1 (en) * 2006-06-02 2008-05-08 Clifford Kraft Medical nanobody
US20080241938A1 (en) * 2006-07-20 2008-10-02 Visigen Biotechnologies, Inc. Automated synthesis or sequencing apparatus and method for making and using same
US7794407B2 (en) 2006-10-23 2010-09-14 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
US8388546B2 (en) 2006-10-23 2013-03-05 Bard Access Systems, Inc. Method of locating the tip of a central venous catheter
US20090275075A1 (en) * 2006-10-26 2009-11-05 Dodd Eric B Methods and systems for ensuring the security of food commodities
US7807344B2 (en) * 2006-10-26 2010-10-05 Global Grain Security, Llc Methods and systems for ensuring the security of grain stores
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US9658178B2 (en) 2012-09-28 2017-05-23 General Electric Company Sensor systems for measuring an interface level in a multi-phase fluid composition
US9589686B2 (en) * 2006-11-16 2017-03-07 General Electric Company Apparatus for detecting contaminants in a liquid and a system for use thereof
US9538657B2 (en) 2012-06-29 2017-01-03 General Electric Company Resonant sensor and an associated sensing method
US9536122B2 (en) 2014-11-04 2017-01-03 General Electric Company Disposable multivariable sensing devices having radio frequency based sensors
US10914698B2 (en) 2006-11-16 2021-02-09 General Electric Company Sensing method and system
EP2677309B9 (de) * 2006-12-14 2014-11-19 Life Technologies Corporation Verfahren zur Sequenzierung einer Nukleinsäure mittels grosser FET-Arrays, geeignet zur Messung in einem begrenzten pH-Bereich
US20080153696A1 (en) * 2006-12-26 2008-06-26 Roth Joseph D Security feature
US7625500B2 (en) * 2006-12-26 2009-12-01 Ncr Corporation Security feature
US8357214B2 (en) 2007-04-26 2013-01-22 Trulite, Inc. Apparatus, system, and method for generating a gas from solid reactant pouches
AU2008279082A1 (en) 2007-07-25 2009-01-29 Trulite, Inc. Apparatus, system, and method to manage the generation and use of hybrid electric power
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
US8734718B2 (en) 2007-08-17 2014-05-27 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having an actively controllable therapeutic agent delivery component
US8162924B2 (en) * 2007-08-17 2012-04-24 The Invention Science Fund I, Llc System, devices, and methods including actively-controllable superoxide water generating systems
US8647292B2 (en) 2007-08-17 2014-02-11 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having components that are actively controllable between two or more wettability states
US8366652B2 (en) 2007-08-17 2013-02-05 The Invention Science Fund I, Llc Systems, devices, and methods including infection-fighting and monitoring shunts
US8460229B2 (en) * 2007-08-17 2013-06-11 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having components that are actively controllable between transmissive and reflective states
US8753304B2 (en) 2007-08-17 2014-06-17 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having acoustically actuatable waveguide components for delivering a sterilizing stimulus to a region proximate a surface of the catheter
US9005263B2 (en) 2007-08-17 2015-04-14 The Invention Science Fund I, Llc System, devices, and methods including actively-controllable sterilizing excitation delivery implants
US8702640B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc System, devices, and methods including catheters configured to monitor and inhibit biofilm formation
US8706211B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having self-cleaning surfaces
US10449330B2 (en) 2007-11-26 2019-10-22 C. R. Bard, Inc. Magnetic element-equipped needle assemblies
US9456766B2 (en) 2007-11-26 2016-10-04 C. R. Bard, Inc. Apparatus for use with needle insertion guidance system
US8849382B2 (en) 2007-11-26 2014-09-30 C. R. Bard, Inc. Apparatus and display methods relating to intravascular placement of a catheter
US10524691B2 (en) 2007-11-26 2020-01-07 C. R. Bard, Inc. Needle assembly including an aligned magnetic element
US10751509B2 (en) 2007-11-26 2020-08-25 C. R. Bard, Inc. Iconic representations for guidance of an indwelling medical device
US8781555B2 (en) 2007-11-26 2014-07-15 C. R. Bard, Inc. System for placement of a catheter including a signal-generating stylet
US9521961B2 (en) 2007-11-26 2016-12-20 C. R. Bard, Inc. Systems and methods for guiding a medical instrument
CN103750858B (zh) 2007-11-26 2017-04-12 C·R·巴德股份有限公司 用于脉管系统内的导管放置的集成系统
US9649048B2 (en) 2007-11-26 2017-05-16 C. R. Bard, Inc. Systems and methods for breaching a sterile field for intravascular placement of a catheter
US8478382B2 (en) 2008-02-11 2013-07-02 C. R. Bard, Inc. Systems and methods for positioning a catheter
US20090242399A1 (en) * 2008-03-25 2009-10-01 Dexcom, Inc. Analyte sensor
JP2011515102A (ja) 2008-03-28 2011-05-19 パシフィック バイオサイエンシーズ オブ カリフォルニア， インコーポレイテッド 核酸シーケンシング用組成物及び方法
CA2728215A1 (en) 2008-06-18 2010-06-24 Innovative Biotherapies, Inc. Methods for enhanced propagation of cells
US10089443B2 (en) 2012-05-15 2018-10-02 Baxter International Inc. Home medical device systems and methods for therapy prescription and tracking, servicing and inventory
US9901714B2 (en) 2008-08-22 2018-02-27 C. R. Bard, Inc. Catheter assembly including ECG sensor and magnetic assemblies
US8610830B2 (en) * 2008-09-11 2013-12-17 Apple Inc. Video rotation method and device
US8437833B2 (en) 2008-10-07 2013-05-07 Bard Access Systems, Inc. Percutaneous magnetic gastrostomy
US8554579B2 (en) 2008-10-13 2013-10-08 Fht, Inc. Management, reporting and benchmarking of medication preparation
US20110160681A1 (en) * 2008-12-04 2011-06-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including catheters having light removable coatings based on a sensed condition
US20120041287A1 (en) 2008-12-04 2012-02-16 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
US20110208023A1 (en) * 2008-12-04 2011-08-25 Goodall Eleanor V Systems, devices, and methods including implantable devices with anti-microbial properties
US8585627B2 (en) 2008-12-04 2013-11-19 The Invention Science Fund I, Llc Systems, devices, and methods including catheters configured to monitor biofilm formation having biofilm spectral information configured as a data structure
US20100312401A1 (en) * 2009-06-08 2010-12-09 Dresser, Inc. Chemical Injection System
US9445734B2 (en) 2009-06-12 2016-09-20 Bard Access Systems, Inc. Devices and methods for endovascular electrography
US9532724B2 (en) 2009-06-12 2017-01-03 Bard Access Systems, Inc. Apparatus and method for catheter navigation using endovascular energy mapping
CN102802514B (zh) 2009-06-12 2015-12-02 巴德阿克塞斯系统股份有限公司 导管末端定位设备
EP2482719A4 (de) 2009-09-29 2016-03-09 Bard Inc C R Dornen zur verwendung in einer vorrichtung zur intravaskulären positionierung eines katheters
US11103213B2 (en) 2009-10-08 2021-08-31 C. R. Bard, Inc. Spacers for use with an ultrasound probe
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
AU2010308329B2 (en) 2009-10-19 2016-10-13 Labrador Diagnostics Llc Integrated health data capture and analysis system
EP2506771A4 (de) * 2009-12-03 2015-01-28 Searete Llc Systeme, vorrichtungen und verfahren mit zur überwachung und hemmung von biofilmformierungen konfigurierten katalysatoren
CN102821679B (zh) 2010-02-02 2016-04-27 C·R·巴德股份有限公司 用于导管导航和末端定位的装置和方法
ES2778041T3 (es) 2010-05-28 2020-08-07 Bard Inc C R Aparato para su uso con sistema de guiado de inserción de aguja
CA2806353A1 (en) 2010-08-09 2012-02-16 C.R. Bard Inc. Support and cover structures for an ultrasound probe head
US20120046562A1 (en) 2010-08-20 2012-02-23 C. R. Bard, Inc. Reconfirmation of ecg-assisted catheter tip placement
EP2632360A4 (de) 2010-10-29 2014-05-21 Bard Inc C R Bioimpedanz-gestützte platzierung einer medizinischen vorrichtung
US8542023B2 (en) 2010-11-09 2013-09-24 General Electric Company Highly selective chemical and biological sensors
RU2587060C2 (ru) * 2010-11-11 2016-06-10 Нестек С.А. Капсула, аппарат для приготовления напитков и система для приготовления продукта питания
CA2835890A1 (en) 2011-07-06 2013-01-10 C.R. Bard, Inc. Needle length determination and calibration for insertion guidance system
USD724745S1 (en) 2011-08-09 2015-03-17 C. R. Bard, Inc. Cap for an ultrasound probe
USD699359S1 (en) 2011-08-09 2014-02-11 C. R. Bard, Inc. Ultrasound probe head
US8997864B2 (en) 2011-08-23 2015-04-07 Harris Corporation Method for hydrocarbon resource recovery including actuator operated positioning of an RF applicator and related apparatus
US8967248B2 (en) 2011-08-23 2015-03-03 Harris Corporation Method for hydrocarbon resource recovery including actuator operated positioning of an RF sensor and related apparatus
US9057712B1 (en) 2011-10-27 2015-06-16 Copilot Ventures Fund Iii Llc Methods of delivery of encapsulated perfluorocarbon taggants
WO2013070775A1 (en) 2011-11-07 2013-05-16 C.R. Bard, Inc Ruggedized ultrasound hydrogel insert
EP2861153A4 (de) 2012-06-15 2016-10-19 Bard Inc C R Vorrichtung und verfahren zum nachweis einer abnehmbaren kappe auf einer ultraschallsonde
US10598650B2 (en) 2012-08-22 2020-03-24 General Electric Company System and method for measuring an operative condition of a machine
DE112013004129T5 (de) 2012-08-22 2015-05-21 General Electric Company Drahtloses System und Verfahren zum Messen einer Betriebsbedingung einer Maschine
US10684268B2 (en) 2012-09-28 2020-06-16 Bl Technologies, Inc. Sensor systems for measuring an interface level in a multi-phase fluid composition
NZ707431A (en) 2012-10-26 2016-05-27 Baxter Corp Englewood Improved image acquisition for medical dose preparation system
EP2911641B1 (de) 2012-10-26 2018-10-17 Baxter Corporation Englewood Verbesserte arbeitsstation für medizinische dosiszubereitung
ITMI20130692A1 (it) 2013-04-26 2014-10-27 Copan Italia Spa Dispositivo e procedimento per il processamento automatico di piastre di coltura per campioni microbiologici
WO2015120256A2 (en) 2014-02-06 2015-08-13 C.R. Bard, Inc. Systems and methods for guidance and placement of an intravascular device
US11107574B2 (en) 2014-09-30 2021-08-31 Baxter Corporation Englewood Management of medication preparation with formulary management
NZ731172A (en) 2014-10-24 2022-07-01 Baxter Corp Englewood Automated exchange of healthcare information for fulfillment of medication doses
AU2015358483A1 (en) 2014-12-05 2017-06-15 Baxter Corporation Englewood Dose preparation data analytics
US10973584B2 (en) 2015-01-19 2021-04-13 Bard Access Systems, Inc. Device and method for vascular access
WO2016130555A1 (en) * 2015-02-10 2016-08-18 Bio-Rad Laboratories, Inc. Dry protein transfer
JP2018507487A (ja) 2015-03-03 2018-03-15 バクスター・コーポレーション・イングルウッドＢａｘｔｅｒ Ｃｏｒｐｏｒａｔｉｏｎ Ｅｎｇｌｅｗｏｏｄ アラート統合を伴う薬局ワークフロー管理
US10349890B2 (en) 2015-06-26 2019-07-16 C. R. Bard, Inc. Connector interface for ECG-based catheter positioning system
US11000207B2 (en) 2016-01-29 2021-05-11 C. R. Bard, Inc. Multiple coil system for tracking a medical device
US20170336428A1 (en) * 2016-05-19 2017-11-23 Roche Molecular Systems, Inc. RFID Tracking Systems And Methods
US20200016567A1 (en) * 2017-03-13 2020-01-16 Arizona Board Of Regents On Behalf Of Arizona State University Heated device for array synthesis
IT201700030049A1 (it) * 2017-03-17 2018-09-17 Open Fields S R L Dispositivo mobile di rilevazione, relativo sistema e procedimento per la rilevazione e il monitoraggio di parametri chimico-fisici all’interno di un contenitore per lo stoccaggio e/o il trasporto di materiale solido
CN107358285B (zh) * 2017-08-17 2023-07-04 中国汽车工业工程有限公司 一种二进制编码带校验规则的硬介质条码
AU2018389222B2 (en) * 2017-12-22 2024-07-11 Electrocore, Inc. Systems and methods for initial provisioning and refilling of medical devices
US10732304B1 (en) * 2018-02-22 2020-08-04 National Technology & Engineering Solutions Of Sandia, Llc Hydrothermal aging-resistant plastic scintillator formulations
RU2679535C1 (ru) * 2018-06-20 2019-02-11 Евгений Петрович Гребенников Светочувствительная защитная метка для аппаратной идентификации
RU2679536C1 (ru) * 2018-06-20 2019-02-11 Евгений Петрович Гребенников Светочувствительная защитная метка для визуальной идентификации
WO2020112233A2 (en) * 2018-09-28 2020-06-04 President And Fellows Of Harvard College Storage of information using mixtures of molecules
CN112867443B (zh) 2018-10-16 2024-04-26 巴德阿克塞斯系统股份有限公司 用于建立电连接的安全装备连接系统及其方法
US12544101B2 (en) 2019-01-30 2026-02-10 Bard Access Systems, Inc. Systems and methods for tracking medical devices
US10818803B1 (en) 2019-07-19 2020-10-27 Globalfoundries Inc. Fin-type field-effect transistors including a two-dimensional material
FR3101568B1 (fr) 2019-10-03 2022-08-05 Aleph Sas Procede de fabrication d’un film comportant des cavites avec determination de profils d’etirage, de masse volumique, d’epaisseur et/ou de porosite du film
CN112295520A (zh) * 2020-10-28 2021-02-02 北京航空航天大学 一种光催化降解反应系统及其制备方法
EP4000597A1 (de) * 2020-11-17 2022-05-25 The Boots Company plc Tetrapeptid und zusammensetzungen mit tetrapeptiden
CN118866098A (zh) * 2024-07-01 2024-10-29 天津大学 一种以光子晶体反射峰为编码的dna信息存储方法

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3119099A (en) * 1960-02-08 1964-01-21 Wells Gardner Electronics Molecular storage unit
US3017025A (en) * 1960-04-26 1962-01-16 Western Electric Co Apparatus for distributing an article to one of several receiving locations
US3781120A (en) * 1970-09-14 1973-12-25 Technicon Instr Self-locating sample receptacle having integral identification label
US3692498A (en) * 1970-10-12 1972-09-19 Lab Aids Inc Chemical testing apparatus
US3713985A (en) * 1970-10-19 1973-01-30 Kantor F Device and method for testing potency of biological control reagents
AT315542B (de) * 1972-09-27 1974-05-27 Johannes Bancsich Dr Probenträger und Vorrichtung zum Einschreiben und Auslesen desselben
DE2503684A1 (de) * 1975-01-30 1976-08-05 Philips Patentverwaltung Einrichtung zum aufteilen einer probe
US4154795A (en) * 1976-07-23 1979-05-15 Dynatech Holdings Limited Microtest plates
US4133642A (en) * 1978-03-10 1979-01-09 Terumo Corporation Pipetting apparatus for automatic analyzer
US4382074A (en) * 1978-03-27 1983-05-03 Hiram Hart Scintillation proximity assay
US4333072A (en) * 1979-08-06 1982-06-01 International Identification Incorporated Identification device
JPS5716359A (en) * 1980-07-03 1982-01-27 Olympus Optical Co Ltd Sample container
JPS58189558A (ja) * 1982-04-28 1983-11-05 Mochida Pharmaceut Co Ltd 免疫学的測定用容器
US4507230A (en) * 1982-05-12 1985-03-26 Research Corporation Peptide synthesis reagents and method of use
US4542102A (en) * 1983-07-05 1985-09-17 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
FR2555744B1 (fr) * 1983-11-30 1986-05-09 Philips Ind Commerciale Eprouvette avec moyens de memorisation des resultats d'analyse
US4778767A (en) * 1984-12-17 1988-10-18 Akzo N.V. Solid phase immunoassay using immunoreagents immobilized on inert synthetic resin surfaces
DE3500180A1 (de) * 1985-01-04 1986-07-10 Ernst Prof. Dr. 7400 Tübingen Bayer Pfropfcopolymerisate aus vernetzten polymeren und polyoxyethylen, verfahren zu ihrer herstellung und ihre verwendung
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
JP2641880B2 (ja) * 1986-08-11 1997-08-20 シスカ・ダイアグノスティックス・インコーポレーテッド 核酸プローブアッセイ法および組成物
US4855909A (en) * 1987-11-20 1989-08-08 Hewlett-Packard Company Forensic sample tracking system and print station therefor
US4927879A (en) * 1988-02-25 1990-05-22 Purdue Research Foundation Method for solid phase membrane mimetics
WO1989008264A1 (en) * 1988-03-04 1989-09-08 Ballies Uwe W Process for automatic, fully selective analysis of blood or its constituents
SE8803602D0 (sv) * 1988-10-11 1988-10-11 Wallac Oy A sample plate with a plurality of sample wells or vials intended for radiolabeled binding assays
SE8804657D0 (sv) * 1988-12-27 1988-12-27 Gerald Potter Colin Support structure for use in a proximity assey
US5319181A (en) * 1992-03-16 1994-06-07 Symbol Technologies, Inc. Method and apparatus for decoding two-dimensional bar code using CCD/CMD camera
FI82144C (fi) * 1989-03-22 1991-01-10 Wallac Oy Foerfarande foer samtidig bestaemning av flera ligander.
US5120662A (en) * 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
US5012236A (en) * 1989-05-26 1991-04-30 Trovan Limited Electromagnetic energy transmission and detection apparatus
US5527681A (en) * 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5242974A (en) * 1991-11-22 1993-09-07 Affymax Technologies N.V. Polymer reversal on solid surfaces
US5547839A (en) * 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
JP2881826B2 (ja) * 1989-07-24 1999-04-12 東ソー株式会社 自動分析装置
US5262772A (en) * 1989-08-16 1993-11-16 Bio Medic Data Systems, Inc. Transponder scanner
EP0502123A4 (en) * 1989-12-01 1992-11-04 Packard Instrument Company, Inc. Scintillation proximity radioimmunoassay using solid scintillator support body
US5100626A (en) * 1990-05-24 1992-03-31 Levin Andrew E Binding assay device with removable cassette and manifold
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
IT1246349B (it) * 1990-07-11 1994-11-17 Healtech Sa Apparecchiatura per l'erogazione di contenitori per uso medico provvisti di indicazione per l'abbinamento permanente a un determinatopaziente
US5252962A (en) * 1990-08-03 1993-10-12 Bio Medic Data Systems System monitoring programmable implantable transponder
AU8868091A (en) * 1990-10-17 1992-05-20 Jack Love Identification and paternity determination by detecting presence or absence of multiple nucleic acid sequences
US5250944A (en) * 1990-10-29 1993-10-05 Bio Medic Data Systems, Inc. Antenna and driving circuit for transmitting and receiving images to and from a passive transponder
DK0562025T3 (da) * 1990-12-06 2001-06-18 Affymetrix Inc Forbindelser og deres anvendelse i en binær syntesestrategi
WO1992013271A1 (en) * 1991-01-25 1992-08-06 Markwell Medical Institute, Inc. Implantable biological fluid measuring device
RU1794088C (ru) * 1991-03-18 1993-02-07 Институт Молекулярной Биологии Ан@ Ссср Способ определени нуклеотидной последовательности ДНК и устройство дл его осуществлени
US5201728A (en) * 1991-05-03 1993-04-13 Giampapa Vincent C Subcutaneous implantable multiple-agent delivery system
US5266926A (en) * 1991-05-31 1993-11-30 Avid Marketing, Inc. Signal transmission and tag power consumption measurement circuit for an inductive reader
US5726014A (en) * 1991-06-27 1998-03-10 Genelabs Technologies, Inc. Screening assay for the detection of DNA-binding molecules
US5235326A (en) * 1991-08-15 1993-08-10 Avid Corporation Multi-mode identification system
EP0604552B1 (de) * 1991-09-18 1997-02-12 Affymax Technologies N.V. Verfahren zur synthese der verschiedenen sammlungen von oligomeren
US5639603A (en) * 1991-09-18 1997-06-17 Affymax Technologies N.V. Synthesizing and screening molecular diversity
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
DE69220888T2 (de) * 1991-11-05 1998-01-29 Perkin Elmer Corp Vorrichtung und Verfahren zur Herstellung von Biopolymeren
US5257011A (en) * 1991-12-03 1993-10-26 Avid Corporation Data altering means for multi-memory electronic identification tag
US5214409A (en) * 1991-12-03 1993-05-25 Avid Corporation Multi-memory electronic identification tag
US5253198A (en) * 1991-12-20 1993-10-12 Syracuse University Three-dimensional optical memory
NL9200207A (nl) * 1992-02-05 1993-09-01 Nedap Nv Implanteerbare biomedische sensorinrichting, in het bijzonder voor meting van de glucoseconcentratie.
EP0556005B1 (de) * 1992-02-14 1996-04-17 AMERSHAM INTERNATIONAL plc Fluoreszente Verbindungen
JP3164403B2 (ja) * 1992-03-27 2001-05-08 オリンパス光学工業株式会社 自動分析装置
JPH05288754A (ja) * 1992-04-10 1993-11-02 B M L:Kk 検体自動分取分配方法とシステム並びに検体表示方法
DE4313807C2 (de) * 1992-04-28 1995-03-09 Olympus Optical Co Reagenz-Container-System für die immunologische Analyse einer Probe in einem automatischen Analysiergerät
FI922004L (fi) * 1992-05-04 1993-11-05 Wallac Oy Maetningsfoerfarande och maetanordning
US5585275A (en) * 1992-09-02 1996-12-17 Arris Pharmaceutical Corporation Pilot apparatus for peptide synthesis and screening
HUT72495A (en) * 1992-10-01 1996-05-28 Cold Spring Harbor Lab Complex combinatorial chemical libraries encoded with tags
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5324483B1 (en) * 1992-10-08 1996-09-24 Warner Lambert Co Apparatus for multiple simultaneous synthesis
NZ257077A (en) * 1992-11-06 1997-05-26 Chiron Mimotopes Pty Ltd Support for synthesis of modular polymers
EP0672254A1 (de) * 1992-12-04 1995-09-20 Eurogenetics N.V. Verfahren und vorrichtung zur automatischen durchführung von immunologischen tests
WO1994013623A1 (en) * 1992-12-11 1994-06-23 Chiron Corporation Synthesis of encoded polymers
US5314829A (en) * 1992-12-18 1994-05-24 California Institute Of Technology Method for imaging informational biological molecules on a semiconductor substrate
DE4306563A1 (de) * 1993-03-03 1994-09-08 Jan Lichtenberg Probenbehälter für zu analysierende Proben
DE650396T1 (de) * 1993-05-17 1995-11-30 Amersham Int Plc Vorrichtung und verfahren zum nachweis zellularer und biochemischer prozesse.
US5306466A (en) * 1993-05-19 1994-04-26 California South Pacific Investors Detection of contaminants in food
AU684510B2 (en) * 1993-05-28 1997-12-18 Chiron Corporation Method for selection of biologically active peptide sequences
DE9308204U1 (de) * 1993-06-01 1993-08-05 Hecht, Manfred, 90765 Fürth Behälter zur Aufnahme temperaturempfindlicher medizinischer Präparationen
EP0708751A1 (de) * 1993-07-16 1996-05-01 The Regents Of The University Of California Synthese einer kombinatorischen matrix von organischen verbindungen durch die verwendung einer kombinatorischen mehrkomponenten matrix synthese
US6087186A (en) * 1993-07-16 2000-07-11 Irori Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
DE4326342A1 (de) * 1993-08-05 1995-02-09 Boehringer Mannheim Gmbh Verfahren zur Analyse von Probenflüssigkeiten
US5397709A (en) * 1993-08-27 1995-03-14 Becton Dickinson And Company System for detecting bacterial growth in a plurality of culture vials
JPH09511486A (ja) * 1994-01-13 1997-11-18 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 合成レセプター、ライブラリー及びこれらの使用
US5679773A (en) * 1995-01-17 1997-10-21 Affymax Technologies N.V Reagants and methods for immobilized polymer synthesis and display
US5549974A (en) * 1994-06-23 1996-08-27 Affymax Technologies Nv Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties
DE9416270U1 (de) * 1994-10-10 1994-12-08 Grieb, Reinhard, 63633 Birstein Laborprobenbehälter
GB2295152A (en) * 1994-11-18 1996-05-22 Pfizer Ltd Preparation of a library of compounds by solid-phase synthesis
WO1996021156A1 (en) * 1995-01-04 1996-07-11 Abbott Laboratories Method for preparing scintillation proximity assay targets
GB9502225D0 (en) * 1995-02-04 1995-03-22 Zeneca Ltd Method
US5609826A (en) * 1995-04-17 1997-03-11 Ontogen Corporation Methods and apparatus for the generation of chemical libraries
CN1181720A (zh) * 1995-04-25 1998-05-13 伊萝莉公司 可远程编程的存储器材料及其应用
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
US5624711A (en) * 1995-04-27 1997-04-29 Affymax Technologies, N.V. Derivatization of solid supports and methods for oligomer synthesis
GB9521943D0 (en) * 1995-10-26 1996-01-03 Univ Hertfordshire Coded particles for process sequence tracking in combinatorial compound library preparation
US5641634A (en) * 1995-11-30 1997-06-24 Mandecki; Wlodek Electronically-indexed solid-phase assay for biomolecules
EP0904540A1 (de) * 1996-03-22 1999-03-31 Ontogen Corporation Methoden für die synthese von räumlich verteilten kombinatorischen bibliotheken mit festgelegten positionen
EP0863858B1 (de) * 1996-04-08 2004-02-04 Glaxo Group Limited Auf masse basierte kodierung und qualitative analyse von kombinatorischen bibliotheken

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AU7257396A (en) 1997-04-28
EP0853497B1 (de) 2007-05-16
EP0853497A2 (de) 1998-07-22
WO1997012680A3 (en) 1997-08-21
DE69637085D1 (de) 2007-06-28
WO1997012680A2 (en) 1997-04-10

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