ATE362534T2 - Menschliche tslp nukleinsäuren und polypeptide - Google Patents
Menschliche tslp nukleinsäuren und polypeptide Download PDFInfo
- Publication number
- ATE362534T2 ATE362534T2 AT99960372T AT99960372T ATE362534T2 AT E362534 T2 ATE362534 T2 AT E362534T2 AT 99960372 T AT99960372 T AT 99960372T AT 99960372 T AT99960372 T AT 99960372T AT E362534 T2 ATE362534 T2 AT E362534T2
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- nucleic acids
- human tslp
- tslp nucleic
- purified
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5418—IL-7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10845298P | 1998-11-13 | 1998-11-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE362534T2 true ATE362534T2 (de) | 2007-06-15 |
Family
ID=22322307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99960372T ATE362534T2 (de) | 1998-11-13 | 1999-11-12 | Menschliche tslp nukleinsäuren und polypeptide |
Country Status (14)
| Country | Link |
|---|---|
| US (8) | US6555520B2 (de) |
| EP (1) | EP1129190B2 (de) |
| JP (3) | JP4454859B2 (de) |
| AT (1) | ATE362534T2 (de) |
| AU (1) | AU755562B2 (de) |
| CA (1) | CA2349762C (de) |
| CY (1) | CY1106806T1 (de) |
| DE (1) | DE69936105T3 (de) |
| DK (1) | DK1129190T4 (de) |
| ES (1) | ES2288036T5 (de) |
| IL (3) | IL143034A0 (de) |
| NZ (1) | NZ512105A (de) |
| PT (1) | PT1129190E (de) |
| WO (1) | WO2000029581A1 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030099947A1 (en) * | 1998-09-21 | 2003-05-29 | Bazan J. Fernando | Mammalian cytokines; related reagents and methods |
| JP2002526079A (ja) * | 1998-09-21 | 2002-08-20 | シェーリング コーポレイション | ヒトインターロイキン−b50、治療的使用 |
| DE69936105T3 (de) * | 1998-11-13 | 2017-07-27 | Immunex Corporation | Menschliche tslp nukleinsäuren und polypeptide |
| US6890734B2 (en) * | 2000-11-10 | 2005-05-10 | Schering Corporation | Nucleic acids encoding a cytokine receptor complex |
| PL371773A1 (en) * | 2001-07-23 | 2005-06-27 | Immunex Corporation | Modified human thymic stromal lymphopoietin |
| AU2003208888B2 (en) * | 2002-02-01 | 2006-10-19 | Merck Sharp & Dohme Llc | Uses of mammalian cytokine; related reagents |
| SI1651247T1 (sl) * | 2003-07-18 | 2009-02-28 | Schering Corp | Zdravljenje in diagnoza neoplazem z uporabo timusnega stromalnega limfopoietina |
| US20050249712A1 (en) * | 2004-03-23 | 2005-11-10 | The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services | Methods for use of TSLP and agonists and antagonists thereof |
| US20090156467A1 (en) * | 2004-07-28 | 2009-06-18 | Zhengbin Yao | Thymic stromal lymphpoietin promoter and use therefor |
| US20060171943A1 (en) * | 2005-02-01 | 2006-08-03 | Amgen Inc. | Compositions and methods of treating fibrotic disorders |
| CA2513350A1 (en) * | 2005-03-02 | 2006-09-02 | Sydney West Area Health Service | Treatment for multiple sclerosis |
| CA2635599C (en) * | 2006-01-13 | 2014-06-17 | Irm Llc | Antibodies against thymic stromal lymphopoietin receptor for treating allergic diseases |
| GB0603683D0 (en) | 2006-02-23 | 2006-04-05 | Novartis Ag | Organic compounds |
| SE532251C2 (sv) * | 2006-11-28 | 2009-11-24 | Theravac Pharmaceuticals Ab | Nya formuleringar av TSLP för behandling av TH2-medierade inflammatoriska sjukdomar genom vaccinering |
| UA120027C2 (uk) | 2006-12-14 | 2019-09-25 | Шерінг-Плау Лтд. | Ізольоване антитіло проти собачого тимусного стромального лімфопоетину (tslp) |
| JP5059119B2 (ja) | 2006-12-14 | 2012-10-24 | シェーリング コーポレイション | 操作された抗tslp抗体 |
| US8501678B2 (en) | 2007-03-06 | 2013-08-06 | Atara Biotherapeutics, Inc. | Variant activin receptor polypeptides and uses thereof |
| US7947646B2 (en) | 2007-03-06 | 2011-05-24 | Amgen Inc. | Variant activin receptor polypeptides |
| US7982016B2 (en) | 2007-09-10 | 2011-07-19 | Amgen Inc. | Antigen binding proteins capable of binding thymic stromal lymphopoietin |
| JP5611222B2 (ja) | 2008-11-26 | 2014-10-22 | アムジエン・インコーポレーテツド | アクチビンiib受容体ポリペプチドの変異体及びその使用 |
| EP2213682A1 (de) | 2009-01-30 | 2010-08-04 | Institut Curie | TSLP fördert Immunevasion und Persistenz von Viren |
| ES2784123T3 (es) | 2009-11-04 | 2020-09-22 | Merck Sharp & Dohme | Anticuerpo anti TSLP genomodificado |
| HK1203384A1 (en) | 2011-12-19 | 2015-12-11 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| AR090915A1 (es) | 2012-05-04 | 2014-12-17 | Intervet Int Bv | Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg |
| EA201590916A1 (ru) | 2012-11-09 | 2016-02-29 | Корнэлл Юниверсити | Низкомолекулярные ингибиторы malt1 |
| UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| AU2014212014A1 (en) | 2013-02-01 | 2015-08-27 | Amgen Inc. | Administration of an anti-activin-A compound to a subject |
| US9708375B2 (en) | 2013-03-15 | 2017-07-18 | Amgen Inc. | Inhibitory polypeptides specific to WNT inhibitors |
| US20160052985A1 (en) * | 2013-04-04 | 2016-02-25 | Ieo - Istituto Europeo Di Oncologia Srl | Thymic stromal lymphopoietin fragments and uses thereof |
| EP3041863A4 (de) | 2013-09-05 | 2017-08-16 | Amgen Inc. | Fc-haltige moleküle mit vorhersagbaren, konsistenten und reproduzierbaren glycoformprofilen |
| US10156562B2 (en) | 2014-05-16 | 2018-12-18 | Amgen Inc. | Assay for detecting Th1 and Th2 cell populations |
| PE20170471A1 (es) | 2014-06-13 | 2017-05-14 | Santa Maria Biotherapeutics Inc | Polipeptidos receptores formulados y metodos relacionados |
| KR101843248B1 (ko) | 2015-03-17 | 2018-03-29 | 고려대학교 세종산학협력단 | 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물 |
| WO2016148437A1 (ko) * | 2015-03-17 | 2016-09-22 | 고려대학교 산학협력단 | 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물 |
| EA038332B1 (ru) | 2015-09-09 | 2021-08-10 | Новартис Аг | Молекулы, связывающиеся с тимусным стромальным лимфопоэтином (tslp), и способы применения таких молекул |
| HRP20210650T1 (hr) | 2015-09-09 | 2021-05-28 | Novartis Ag | Protutijela koja vežu timusni stromalni limfopoetin (tslp) i postupci uporabe protutijela |
| CA3056011A1 (en) | 2017-03-14 | 2018-09-20 | Amgen Inc. | Control of total afucosylated glycoforms of antibodies produced in cell culture |
| US12325737B2 (en) | 2018-03-26 | 2025-06-10 | Amgen Inc. | Total afucosylated glycoforms of antibodies produced in cell culture |
| CN109678957B (zh) * | 2018-12-06 | 2021-04-06 | 浙江工业大学 | 一种抗人tslp单克隆抗体及其制备与应用 |
| KR102156335B1 (ko) * | 2018-12-28 | 2020-09-16 | (주)메디톡스 | 외래 단백질을 발현하는 미생물, 및 그의 용도 |
| BR112022005583A2 (pt) | 2019-09-26 | 2022-09-20 | Amgen Inc | Métodos para a produção de composições de anticorpos |
| US20230273126A1 (en) | 2020-06-04 | 2023-08-31 | Amgen Inc. | Assessment of cleaning procedures of a biotherapeutic manufacturing process |
| KR20230087539A (ko) | 2020-10-15 | 2023-06-16 | 암젠 인크 | 항체 생산 방법에서의 상대적인 비결합 글리칸 |
| EP4352094A1 (de) | 2021-06-07 | 2024-04-17 | Amgen Inc. | Verwendung von fucosidase zur steuerung des afucosylierungsniveaus glykosylierter proteine |
| US20250076309A1 (en) | 2021-10-05 | 2025-03-06 | Amgen Inc. | Fc-gamma receptor ii binding and glycan content |
| WO2023215725A1 (en) | 2022-05-02 | 2023-11-09 | Fred Hutchinson Cancer Center | Compositions and methods for cellular immunotherapy |
| US12110324B2 (en) | 2022-07-22 | 2024-10-08 | Flagship Pioneering Innovations Vi, Llc | Antigen binding molecules targeting thymic stromal lymphopoietin (TSLP) |
| AU2024256160A1 (en) | 2023-04-20 | 2025-10-02 | Amgen Inc. | Methods of determining relative unpaired glycan content |
| WO2025038600A1 (en) | 2023-08-14 | 2025-02-20 | Amgen Inc. | Methods for reducing yellow color |
| AU2024334289A1 (en) | 2023-08-25 | 2026-04-09 | Proteologix Us Inc. | Anti-il-13 multispecific antibody constructs and uses thereof |
| WO2025101820A1 (en) | 2023-11-08 | 2025-05-15 | Fred Hutchinson Cancer Center | Compositions and methods for cellular immunotherapy |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5011912A (en) * | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
| ATE188610T1 (de) | 1992-04-30 | 2000-01-15 | Amgen Inc | Methoden zur behandlung von interleukin- 1 und - tumor - nekrose - faktor - verursachten krankheiten |
| WO1995000103A2 (en) | 1993-06-15 | 1995-01-05 | Il-Yang Pharm. Co., Ltd. | Anti-sense oligodeoxynucleotide to fibrogenic cytokines and use thereof |
| GB9702944D0 (en) | 1997-02-13 | 1997-04-02 | Univ Manchester | Reducing fibrosis |
| US6844170B1 (en) * | 1998-03-19 | 2005-01-18 | Human Genome Sciences, Inc. | Cytokine receptor common gamma chain like |
| AU3072799A (en) | 1998-03-19 | 1999-10-11 | Human Genome Sciences, Inc. | Cytokine receptor common gamma chain like |
| US6982320B2 (en) | 1998-03-19 | 2006-01-03 | Human Genome Sciences, Inc. | Cytokine receptor common gamma chain like |
| US20030099947A1 (en) * | 1998-09-21 | 2003-05-29 | Bazan J. Fernando | Mammalian cytokines; related reagents and methods |
| JP2002526079A (ja) * | 1998-09-21 | 2002-08-20 | シェーリング コーポレイション | ヒトインターロイキン−b50、治療的使用 |
| DE69936105T3 (de) | 1998-11-13 | 2017-07-27 | Immunex Corporation | Menschliche tslp nukleinsäuren und polypeptide |
| EP1140976A4 (de) | 1998-12-30 | 2003-05-21 | Millennium Pharm Inc | Sekretierte proteine und ihre verwendungen. |
| US20010021380A1 (en) | 1999-04-19 | 2001-09-13 | Pluenneke John D. | Soluble tumor necrosis factor receptor treatment of medical disorders |
| EP1712239A3 (de) | 2000-05-12 | 2007-08-22 | Immunex Corporation | Interleukin-1 Inhibitoren zur Behandlung von Erkrankungen |
| US6955895B2 (en) | 2000-06-28 | 2005-10-18 | Whitehead Institute For Biomedical Research | Thymic stromal lymphopoietin receptor molecules and uses thereof |
| ES2391124T3 (es) | 2000-06-28 | 2012-11-21 | Amgen Inc. | Moléculas de receptor de linfopoyetina estromal tímica y usos de las mismas |
| AU2003208888B2 (en) * | 2002-02-01 | 2006-10-19 | Merck Sharp & Dohme Llc | Uses of mammalian cytokine; related reagents |
| HRP20020453A2 (en) | 2002-05-23 | 2003-12-31 | Pliva D D | 1,3-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof |
| KR101317045B1 (ko) | 2002-09-06 | 2013-10-16 | 암젠 인코포레이티드 | 치료학적 인체 항-il-1r1 모노클로날 항체 |
| SI1651247T1 (sl) | 2003-07-18 | 2009-02-28 | Schering Corp | Zdravljenje in diagnoza neoplazem z uporabo timusnega stromalnega limfopoietina |
| US20050249712A1 (en) * | 2004-03-23 | 2005-11-10 | The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services | Methods for use of TSLP and agonists and antagonists thereof |
| EP1793856A2 (de) | 2004-08-20 | 2007-06-13 | Amgen Inc. | Verfahren und zusammensetzungen zur behandlung allergischer entzündungen |
| CA2635599C (en) | 2006-01-13 | 2014-06-17 | Irm Llc | Antibodies against thymic stromal lymphopoietin receptor for treating allergic diseases |
| GB0603683D0 (en) | 2006-02-23 | 2006-04-05 | Novartis Ag | Organic compounds |
| JP5059119B2 (ja) | 2006-12-14 | 2012-10-24 | シェーリング コーポレイション | 操作された抗tslp抗体 |
| CN102027012A (zh) | 2007-06-20 | 2011-04-20 | Irm责任有限公司 | 用于治疗变应性疾病的方法和组合物 |
| US9157749B2 (en) † | 2011-04-11 | 2015-10-13 | Clarion Co., Ltd. | Position calculation method and position calculation apparatus |
-
1999
- 1999-11-12 DE DE69936105.2T patent/DE69936105T3/de not_active Expired - Lifetime
- 1999-11-12 DK DK99960372.3T patent/DK1129190T4/en active
- 1999-11-12 IL IL14303499A patent/IL143034A0/xx unknown
- 1999-11-12 ES ES99960372.3T patent/ES2288036T5/es not_active Expired - Lifetime
- 1999-11-12 WO PCT/US1999/027069 patent/WO2000029581A1/en not_active Ceased
- 1999-11-12 AU AU17266/00A patent/AU755562B2/en not_active Expired
- 1999-11-12 AT AT99960372T patent/ATE362534T2/de active
- 1999-11-12 PT PT99960372T patent/PT1129190E/pt unknown
- 1999-11-12 JP JP2000582564A patent/JP4454859B2/ja not_active Expired - Lifetime
- 1999-11-12 NZ NZ512105A patent/NZ512105A/en not_active IP Right Cessation
- 1999-11-12 EP EP99960372.3A patent/EP1129190B2/de not_active Expired - Lifetime
- 1999-11-12 CA CA2349762A patent/CA2349762C/en not_active Expired - Lifetime
-
2001
- 2001-05-08 IL IL143034A patent/IL143034A/en not_active IP Right Cessation
- 2001-05-09 US US09/852,391 patent/US6555520B2/en not_active Expired - Lifetime
-
2003
- 2003-02-27 US US10/376,406 patent/US7304144B2/en not_active Expired - Lifetime
-
2006
- 2006-06-13 US US11/452,762 patent/US7405058B2/en not_active Expired - Fee Related
-
2007
- 2007-08-08 CY CY20071101061T patent/CY1106806T1/el unknown
-
2008
- 2008-07-28 US US12/220,879 patent/US7786271B2/en not_active Expired - Fee Related
- 2008-12-09 IL IL195812A patent/IL195812A/en not_active IP Right Cessation
-
2009
- 2009-12-08 JP JP2009278611A patent/JP5632155B2/ja not_active Expired - Lifetime
-
2010
- 2010-06-23 US US12/822,050 patent/US20100266601A1/en not_active Abandoned
-
2011
- 2011-09-23 US US13/243,837 patent/US8444979B2/en not_active Expired - Fee Related
-
2012
- 2012-12-13 JP JP2012271983A patent/JP2013078331A/ja active Pending
-
2013
- 2013-05-06 US US13/887,893 patent/US20130225490A1/en not_active Abandoned
-
2014
- 2014-09-16 US US14/487,564 patent/US9346870B2/en not_active Expired - Fee Related
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| UEP | Publication of translation of european patent specification |
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