ATE362768T1 - Prb2/p130 peptidinhibitoren der cdk2 kinaseaktivität - Google Patents

Prb2/p130 peptidinhibitoren der cdk2 kinaseaktivität

Info

Publication number: ATE362768T1
Authority: AT; Austria
Prior art keywords: kinase activity; prb2; cdk2 kinase; peptide inhibitors; cdk2
Prior art date: 1997-08-21

Application number

AT98939257T

Other languages

English (en)

Inventor

Antonio Giordano

Original Assignee

Univ Jefferson

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-21

Filing date

1998-08-06

Publication date

2007-06-15

1998-08-06 Application filed by Univ Jefferson filed Critical Univ Jefferson

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE362768T1 publication Critical patent/ATE362768T1/de

Links

230000000694 effects Effects 0.000 title abstract 3
102100033943 Basic salivary proline-rich protein 2 Human genes 0.000 title 1
102000015792 Cyclin-Dependent Kinase 2 Human genes 0.000 title 1
108010024986 Cyclin-Dependent Kinase 2 Proteins 0.000 title 1
101001068639 Homo sapiens Basic salivary proline-rich protein 2 Proteins 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
108091000080 Phosphotransferase Proteins 0.000 abstract 2
102100022828 Retinoblastoma-like protein 2 Human genes 0.000 abstract 2
108050002651 Retinoblastoma-like protein 2 Proteins 0.000 abstract 2
101150073031 cdk2 gene Proteins 0.000 abstract 2
102000020233 phosphotransferase Human genes 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
239000012634 fragment Substances 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)

AT98939257T 1997-08-21 1998-08-06 Prb2/p130 peptidinhibitoren der cdk2 kinaseaktivität ATE362768T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5620797P	1997-08-21	1997-08-21

Publications (1)

Publication Number	Publication Date
ATE362768T1 true ATE362768T1 (de)	2007-06-15

Family

ID=22002895

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98939257T ATE362768T1 (de)	1997-08-21	1998-08-06	Prb2/p130 peptidinhibitoren der cdk2 kinaseaktivität

Country Status (7)

Country	Link
US (1)	US6297357B1 (de)
EP (1)	EP1015015B1 (de)
JP (1)	JP4323716B2 (de)
AT (1)	ATE362768T1 (de)
CA (1)	CA2301333C (de)
DE (1)	DE69837808T2 (de)
WO (1)	WO1999008700A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1629090B1 (de) *	2002-11-06	2014-03-05	iBio, Inc.	Expression von fremdsequenzen in pflanzen unter verwendung eines trans-aktivierungssystems
US7692063B2 (en) *	2002-11-12	2010-04-06	Ibio, Inc.	Production of foreign nucleic acids and polypeptides in sprout systems
US7683238B2 (en) *	2002-11-12	2010-03-23	iBio, Inc. and Fraunhofer USA, Inc.	Production of pharmaceutically active proteins in sprouted seedlings
ES2531125T3 (es)	2003-02-03	2015-03-10	Ibio Inc	Sistema para la expresión de genes en plantas
ES2532609T3 (es) *	2004-02-20	2015-03-30	Ibio, Inc.	Sistemas y métodos para expresión clonales en plantas
US20090054333A1 (en) *	2006-10-17	2009-02-26	Antonio Giordano	Peptide inhibitors of cyclin-dependent kinase activity and uses thereof
US7470670B2 (en) *	2006-10-17	2008-12-30	Sbarro Health Research Organization, Inc.	Peptide inhibitors of cyclin-dependent kinase activity and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5596079A (en) *	1991-12-16	1997-01-21	Smith; James R.	Mimetics of senescent cell derived inhibitors of DNA synthesis
US5496731A (en)	1993-03-25	1996-03-05	Xu; Hong-Ji	Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy
US5457049A (en) *	1993-08-12	1995-10-10	Temple University - Of The Commonwealth System Of Higher Education	Tumor suppressor protein pRb2, related gene products, and DNA encoding therefor
US5688665A (en) *	1994-01-07	1997-11-18	Fred Hutchinson Cancer Research Center	Isolated nucleic acid molecules encoding the p27 KIP-1 protein
US5625031A (en)	1994-02-08	1997-04-29	Bristol-Myers Squibb Company	Peptide inhibitors of the p33cdk2 and p34cdc2 cell cycle regulatory kinases and human papillomavirus E7 oncoprotein
US5672508A (en) *	1996-01-23	1997-09-30	Mitotix, Inc.	Inhibitors of cell-cycle progression, and uses related thereto

1998
- 1998-08-06 WO PCT/US1998/016381 patent/WO1999008700A1/en not_active Ceased
- 1998-08-06 EP EP98939257A patent/EP1015015B1/de not_active Expired - Lifetime
- 1998-08-06 CA CA2301333A patent/CA2301333C/en not_active Expired - Lifetime
- 1998-08-06 JP JP2000509437A patent/JP4323716B2/ja not_active Expired - Fee Related
- 1998-08-06 DE DE69837808T patent/DE69837808T2/de not_active Expired - Lifetime
- 1998-08-06 AT AT98939257T patent/ATE362768T1/de not_active IP Right Cessation
- 1998-08-06 US US09/130,425 patent/US6297357B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP2002500160A (ja)	2002-01-08
CA2301333C (en)	2011-12-06
DE69837808T2 (de)	2008-02-07
US6297357B1 (en)	2001-10-02
WO1999008700A1 (en)	1999-02-25
EP1015015A1 (de)	2000-07-05
EP1015015B1 (de)	2007-05-23
CA2301333A1 (en)	1999-02-25
EP1015015A4 (de)	2004-12-08
JP4323716B2 (ja)	2009-09-02
DE69837808D1 (de)	2007-07-05

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Legal Events

Date	Code	Title	Description
2007-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties