ATE362917T1 - Substituierte pyrinderivate zur steuerung von chemischer synaptischer übertragung - Google Patents
Substituierte pyrinderivate zur steuerung von chemischer synaptischer übertragungInfo
- Publication number
- ATE362917T1 ATE362917T1 AT01910414T AT01910414T ATE362917T1 AT E362917 T1 ATE362917 T1 AT E362917T1 AT 01910414 T AT01910414 T AT 01910414T AT 01910414 T AT01910414 T AT 01910414T AT E362917 T1 ATE362917 T1 AT E362917T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- pyrine
- derivatives
- synaptic transmission
- controlling chemical
- Prior art date
Links
- 230000005062 synaptic transmission Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000003957 neurotransmitter release Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- -1 pyridyl ethers Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/496,538 US20010034357A1 (en) | 2000-02-02 | 2000-02-02 | Substituted pyridine compounds useful for controlling chemical synaptic transmission |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE362917T1 true ATE362917T1 (de) | 2007-06-15 |
Family
ID=23973070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01910414T ATE362917T1 (de) | 2000-02-02 | 2001-02-01 | Substituierte pyrinderivate zur steuerung von chemischer synaptischer übertragung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20010034357A1 (de) |
| EP (1) | EP1257535B1 (de) |
| JP (1) | JP2003523973A (de) |
| AT (1) | ATE362917T1 (de) |
| CA (1) | CA2397798C (de) |
| DE (1) | DE60128543T2 (de) |
| ES (1) | ES2286105T3 (de) |
| MX (1) | MXPA02007498A (de) |
| WO (1) | WO2001056991A1 (de) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2711655A1 (de) * | 1977-03-17 | 1978-09-21 | Basf Ag | Pyridinyl-aminoalkylaether |
| EP0287908A3 (de) * | 1987-04-18 | 1989-12-27 | ASTA Medica Aktiengesellschaft | Neue stickstoffhaltige, cycloaliphatische Verbindungen mit einem Aminosäurerest sowie einem Pyridinrest |
| US5852041A (en) * | 1993-04-07 | 1998-12-22 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acethylcholine receptors |
| US5616707A (en) * | 1995-01-06 | 1997-04-01 | Crooks; Peter A. | Compounds which are useful for prevention and treatment of central nervous system disorders |
| IL118279A (en) * | 1995-06-07 | 2006-10-05 | Abbott Lab | Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission |
| US6166048A (en) * | 1999-04-20 | 2000-12-26 | Targacept, Inc. | Pharmaceutical compositions for inhibition of cytokine production and secretion |
| WO1997046544A1 (en) * | 1996-06-03 | 1997-12-11 | Akzo Nobel N.V. | Acid catalysed process for preparing 2-mercaptobenzothiazole and derivatives thereof |
| MXPA00009619A (es) * | 1998-04-02 | 2006-03-09 | Targacept Inc | Composiciones farmaceuticas y metodos de uso. |
| MXPA01012202A (es) * | 1999-05-24 | 2002-06-21 | Targacept Inc | Composiciones farmaceuticas y metodos de uso. |
-
2000
- 2000-02-02 US US09/496,538 patent/US20010034357A1/en not_active Abandoned
-
2001
- 2001-02-01 AT AT01910414T patent/ATE362917T1/de not_active IP Right Cessation
- 2001-02-01 EP EP01910414A patent/EP1257535B1/de not_active Expired - Lifetime
- 2001-02-01 JP JP2001556841A patent/JP2003523973A/ja active Pending
- 2001-02-01 ES ES01910414T patent/ES2286105T3/es not_active Expired - Lifetime
- 2001-02-01 WO PCT/US2001/003546 patent/WO2001056991A1/en not_active Ceased
- 2001-02-01 DE DE60128543T patent/DE60128543T2/de not_active Expired - Lifetime
- 2001-02-01 CA CA2397798A patent/CA2397798C/en not_active Expired - Fee Related
- 2001-02-01 MX MXPA02007498A patent/MXPA02007498A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP1257535B1 (de) | 2007-05-23 |
| WO2001056991A1 (en) | 2001-08-09 |
| US20010034357A1 (en) | 2001-10-25 |
| EP1257535A1 (de) | 2002-11-20 |
| ES2286105T3 (es) | 2007-12-01 |
| MXPA02007498A (es) | 2003-01-28 |
| CA2397798A1 (en) | 2001-08-09 |
| DE60128543T2 (de) | 2008-01-31 |
| JP2003523973A (ja) | 2003-08-12 |
| CA2397798C (en) | 2011-01-04 |
| DE60128543D1 (de) | 2007-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |