ATE362917T1 - Substituierte pyrinderivate zur steuerung von chemischer synaptischer übertragung - Google Patents

Substituierte pyrinderivate zur steuerung von chemischer synaptischer übertragung

Info

Publication number
ATE362917T1
ATE362917T1 AT01910414T AT01910414T ATE362917T1 AT E362917 T1 ATE362917 T1 AT E362917T1 AT 01910414 T AT01910414 T AT 01910414T AT 01910414 T AT01910414 T AT 01910414T AT E362917 T1 ATE362917 T1 AT E362917T1
Authority
AT
Austria
Prior art keywords
substituted
pyrine
derivatives
synaptic transmission
controlling chemical
Prior art date
Application number
AT01910414T
Other languages
English (en)
Inventor
Nan-Horng Lin
Liming Dong
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE362917T1 publication Critical patent/ATE362917T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT01910414T 2000-02-02 2001-02-01 Substituierte pyrinderivate zur steuerung von chemischer synaptischer übertragung ATE362917T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/496,538 US20010034357A1 (en) 2000-02-02 2000-02-02 Substituted pyridine compounds useful for controlling chemical synaptic transmission

Publications (1)

Publication Number Publication Date
ATE362917T1 true ATE362917T1 (de) 2007-06-15

Family

ID=23973070

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01910414T ATE362917T1 (de) 2000-02-02 2001-02-01 Substituierte pyrinderivate zur steuerung von chemischer synaptischer übertragung

Country Status (9)

Country Link
US (1) US20010034357A1 (de)
EP (1) EP1257535B1 (de)
JP (1) JP2003523973A (de)
AT (1) ATE362917T1 (de)
CA (1) CA2397798C (de)
DE (1) DE60128543T2 (de)
ES (1) ES2286105T3 (de)
MX (1) MXPA02007498A (de)
WO (1) WO2001056991A1 (de)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2711655A1 (de) * 1977-03-17 1978-09-21 Basf Ag Pyridinyl-aminoalkylaether
EP0287908A3 (de) * 1987-04-18 1989-12-27 ASTA Medica Aktiengesellschaft Neue stickstoffhaltige, cycloaliphatische Verbindungen mit einem Aminosäurerest sowie einem Pyridinrest
US5852041A (en) * 1993-04-07 1998-12-22 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acethylcholine receptors
US5616707A (en) * 1995-01-06 1997-04-01 Crooks; Peter A. Compounds which are useful for prevention and treatment of central nervous system disorders
IL118279A (en) * 1995-06-07 2006-10-05 Abbott Lab Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission
US6166048A (en) * 1999-04-20 2000-12-26 Targacept, Inc. Pharmaceutical compositions for inhibition of cytokine production and secretion
WO1997046544A1 (en) * 1996-06-03 1997-12-11 Akzo Nobel N.V. Acid catalysed process for preparing 2-mercaptobenzothiazole and derivatives thereof
MXPA00009619A (es) * 1998-04-02 2006-03-09 Targacept Inc Composiciones farmaceuticas y metodos de uso.
MXPA01012202A (es) * 1999-05-24 2002-06-21 Targacept Inc Composiciones farmaceuticas y metodos de uso.

Also Published As

Publication number Publication date
EP1257535B1 (de) 2007-05-23
WO2001056991A1 (en) 2001-08-09
US20010034357A1 (en) 2001-10-25
EP1257535A1 (de) 2002-11-20
ES2286105T3 (es) 2007-12-01
MXPA02007498A (es) 2003-01-28
CA2397798A1 (en) 2001-08-09
DE60128543T2 (de) 2008-01-31
JP2003523973A (ja) 2003-08-12
CA2397798C (en) 2011-01-04
DE60128543D1 (de) 2007-07-05

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Legal Events

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