ATE363480T1 - Alkylammoniumsalze von omeprazol und esomeprazol - Google Patents

Alkylammoniumsalze von omeprazol und esomeprazol

Info

Publication number: ATE363480T1
Authority: AT; Austria
Prior art keywords: sub; esomeprazole; omeprazole; salts; relates
Prior art date: 2002-03-05

Application number

AT03707279T

Other languages

English (en)

Inventor

Mikael Dahlstroem

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-05

Filing date

2003-03-04

Publication date

2007-06-15

2003-03-04 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE363480T1 publication Critical patent/ATE363480T1/de

Links

SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical class N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 title abstract 3
SUBDBMMJDZJVOS-DEOSSOPVSA-N esomeprazole Chemical class C([S@](=O)C1=NC2=CC=C(C=C2N1)OC)C1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-DEOSSOPVSA-N 0.000 title abstract 3
229960004770 esomeprazole Drugs 0.000 title abstract 3
229960000381 omeprazole Drugs 0.000 title abstract 3
150000003839 salts Chemical class 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
-1 4-methoxy-3,5-dimethyl-2-pyridinyl Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
150000003973 alkyl amines Chemical class 0.000 abstract 1
125000005210 alkyl ammonium group Chemical group 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives

Landscapes

Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Manufacturing & Machinery (AREA)
Ceramic Engineering (AREA)
Health & Medical Sciences (AREA)
Inorganic Chemistry (AREA)
Materials Engineering (AREA)
Structural Engineering (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Paper (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT03707279T 2002-03-05 2003-03-04 Alkylammoniumsalze von omeprazol und esomeprazol ATE363480T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US36218702P	2002-03-05	2002-03-05

Publications (1)

Publication Number	Publication Date
ATE363480T1 true ATE363480T1 (de)	2007-06-15

Family

ID=27789148

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03707279T ATE363480T1 (de)	2002-03-05	2003-03-04	Alkylammoniumsalze von omeprazol und esomeprazol

Country Status (12)

Country	Link
US (1)	US7345061B2 (de)
EP (1)	EP1487818B1 (de)
JP (1)	JP4495465B2 (de)
AT (1)	ATE363480T1 (de)
AU (1)	AU2003208686A1 (de)
CA (1)	CA2474246C (de)
CY (1)	CY1108024T1 (de)
DE (1)	DE60314105T2 (de)
DK (1)	DK1487818T3 (de)
ES (1)	ES2286408T3 (de)
PT (1)	PT1487818E (de)
WO (1)	WO2003074514A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1842525A (zh)	2003-05-05	2006-10-04	兰贝克赛实验室有限公司	苯并咪唑衍生物的钡盐
SE0302381D0 (sv)	2003-09-04	2003-09-04	Astrazeneca Ab	New salts I
SE0302382D0 (sv) *	2003-09-04	2003-09-04	Astrazeneca Ab	New salts II
WO2006013960A1 (ja) *	2004-08-06	2006-02-09	Eisai R & D Management Co., Ltd.	ベンズイミダゾール誘導体とアミンとの塩およびその製造方法
US7576219B2 (en)	2005-10-26	2009-08-18	Hanmi Pharm. Co., Ltd	Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same
EP1801110A1 (de) *	2005-12-22	2007-06-27	KRKA, tovarna zdravil, d.d., Novo mesto	Argininsalz des Esomeprazols
CN101460481A (zh) *	2006-06-07	2009-06-17	阿斯利康(瑞典)有限公司	制备埃索美拉唑的铵盐的新方法
EP2114919A2 (de)	2007-01-31	2009-11-11	Krka Tovarna Zdravil, D.D., Novo Mesto	Verfahren zur herstellung von optisch reinem omeprazol durch salzbildung mit einem chiralen amin oder behandlung mit einem enantiomer umwandelnden enzym und chromatographische auftrennung
EA201000101A1 (ru)	2007-07-16	2010-08-30	Астразенека Аб	Производные пиримидина 934
US20100280077A1 (en) *	2007-12-18	2010-11-04	Watson Pharma Private Limited	Process for Preparation of Stable Amorphous R-Lansoprazole
EP2303868A2 (de) *	2008-05-14	2011-04-06	Watson Pharma Private Limited	Stabiles r(+)-lansoprazolaminsalz und verfahren zu seiner herstellung
WO2011058569A1 (en)	2009-11-12	2011-05-19	Hetero Research Foundation	Process for the resolution of omeprazole
CN110935190A (zh) *	2019-12-20	2020-03-31	达州瓮福蓝剑化工有限责任公司	一种铵盐连续结晶工艺及装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE7804231L (sv) *	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
SE8301182D0 (sv)	1983-03-04	1983-03-04	Haessle Ab	Novel compounds
GB2189698A (en) *	1986-04-30	1987-11-04	Haessle Ab	Coated omeprazole tablets
FR2692146B1 (fr) *	1992-06-16	1995-06-02	Ethypharm Sa	Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
SE9301830D0 (sv) *	1993-05-28	1993-05-28	Ab Astra	New compounds
DK0723436T3 (da) *	1994-07-08	2001-11-26	Astrazeneca Ab	Tabletteret flerenhedsdoseringsform
SE504459C2 (sv) *	1994-07-15	1997-02-17	Astra Ab	Förfarande för framställning av substituerade sulfoxider
SE508669C2 (sv) *	1996-04-26	1998-10-26	Astra Ab	Nytt förfarande
SE510650C2 (sv) *	1997-05-30	1999-06-14	Astra Ab	Ny förening
US6048981A (en) *	1998-04-22	2000-04-11	Torcan Chemical Ltd.	Magnesium omeprazole and process for its preparation

2003
- 2003-03-04 ES ES03707279T patent/ES2286408T3/es not_active Expired - Lifetime
- 2003-03-04 DE DE60314105T patent/DE60314105T2/de not_active Expired - Lifetime
- 2003-03-04 AU AU2003208686A patent/AU2003208686A1/en not_active Abandoned
- 2003-03-04 DK DK03707279T patent/DK1487818T3/da active
- 2003-03-04 WO PCT/SE2003/000378 patent/WO2003074514A1/en not_active Ceased
- 2003-03-04 EP EP03707279A patent/EP1487818B1/de not_active Expired - Lifetime
- 2003-03-04 US US10/506,345 patent/US7345061B2/en not_active Expired - Fee Related
- 2003-03-04 CA CA2474246A patent/CA2474246C/en not_active Expired - Fee Related
- 2003-03-04 JP JP2003572982A patent/JP4495465B2/ja not_active Expired - Fee Related
- 2003-03-04 PT PT03707279T patent/PT1487818E/pt unknown
- 2003-03-04 AT AT03707279T patent/ATE363480T1/de active
2007
- 2007-07-20 CY CY20071100973T patent/CY1108024T1/el unknown

Also Published As

Publication number	Publication date
JP2005521693A (ja)	2005-07-21
HK1070886A1 (en)	2005-06-30
US7345061B2 (en)	2008-03-18
CA2474246C (en)	2010-06-29
DE60314105D1 (de)	2007-07-12
ES2286408T3 (es)	2007-12-01
US20050182099A1 (en)	2005-08-18
CY1108024T1 (el)	2013-09-04
DK1487818T3 (da)	2007-08-20
CA2474246A1 (en)	2003-09-12
EP1487818B1 (de)	2007-05-30
EP1487818A1 (de)	2004-12-22
WO2003074514A1 (en)	2003-09-12
AU2003208686A1 (en)	2003-09-16
DE60314105T2 (de)	2008-01-24
JP4495465B2 (ja)	2010-07-07
PT1487818E (pt)	2007-07-18

Legal Events

Date

Code

Title

Description

2007-10-15

UEP

Publication of translation of european patent specification

Ref document number: 1487818

Country of ref document: EP

Publication	Publication Date	Title
CY1108024T1 (el)	2013-09-04	Αλατα αλκυλαμμωνιου ομεπραζολης και εσομεπραζολης
DK0969819T3 (da)	2003-05-19	Ny krystalform af omeprazol
SE9900274D0 (sv)	1999-01-28	New compound
ES2397380T3 (es)	2013-03-06	Procedimiento para preparar compuestos activos ópticamente puros
ES2383679T3 (es)	2012-06-25	Procedimiento para la preparación de (S)-pantoprazol
SE0302382D0 (sv)	2003-09-04	New salts II
SE0302381D0 (sv)	2003-09-04	New salts I
MXPA05009183A (es)	2005-10-20	Polimorfos de s-omeprazol.
MY118724A (en)	2005-01-31	New crystalline form of omeprazole
CN1960987A (zh)	2007-05-09	制备吡啶－2－基甲基亚磺酰基－1h－苯并咪唑类化合物的方法
YU32301A (sh)	2005-07-19	Novi kristalni oblik omeprazola
KR20070031945A (ko)	2007-03-20	피리딘-2-일메틸설피닐-1ｈ-벤즈이미다졸 화합물의 제조방법