ATE364087T1 - Regulierung der expression von eer-7, ein mitglied der lysyl oxidase genfamilie, durch oestrogenrezeptoren - Google Patents

Regulierung der expression von eer-7, ein mitglied der lysyl oxidase genfamilie, durch oestrogenrezeptoren

Info

Publication number
ATE364087T1
ATE364087T1 AT01963850T AT01963850T ATE364087T1 AT E364087 T1 ATE364087 T1 AT E364087T1 AT 01963850 T AT01963850 T AT 01963850T AT 01963850 T AT01963850 T AT 01963850T AT E364087 T1 ATE364087 T1 AT E364087T1
Authority
AT
Austria
Prior art keywords
eer
lysyl oxidase
estrogen receptors
regulation
expression
Prior art date
Application number
AT01963850T
Other languages
English (en)
Inventor
Mark Evans
Marshall Scicchitano
Ashok Bapat
Eric Beer
Ramesh Bhat
Elissa Ferris
Robert Mastroeni
Jianziong Zhang
Sotirios Karathanasis
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE364087T1 publication Critical patent/ATE364087T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01963850T 2000-08-08 2001-08-08 Regulierung der expression von eer-7, ein mitglied der lysyl oxidase genfamilie, durch oestrogenrezeptoren ATE364087T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22376300P 2000-08-08 2000-08-08
US25583800P 2000-12-15 2000-12-15

Publications (1)

Publication Number Publication Date
ATE364087T1 true ATE364087T1 (de) 2007-06-15

Family

ID=26918106

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01963850T ATE364087T1 (de) 2000-08-08 2001-08-08 Regulierung der expression von eer-7, ein mitglied der lysyl oxidase genfamilie, durch oestrogenrezeptoren

Country Status (11)

Country Link
US (2) US7208300B2 (de)
EP (1) EP1354046B1 (de)
JP (1) JP2004505631A (de)
AT (1) ATE364087T1 (de)
AU (1) AU2001284769A1 (de)
BR (1) BR0113257A (de)
CA (1) CA2418952A1 (de)
DE (1) DE60128830T2 (de)
IL (1) IL154036A0 (de)
MX (1) MXPA03001196A (de)
WO (1) WO2002012470A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
US8119599B2 (en) * 2001-08-31 2012-02-21 Orthopeutics, L.P. Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
US20070021365A1 (en) * 2005-06-21 2007-01-25 The Board Of Trustees Of The Leland Stanford Junior University Inhibition of Lysyl oxidase for treating tumor growth and diagnostics relating thereto
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
US9687262B2 (en) * 2005-11-30 2017-06-27 CARDINAL HEALTH SWITZERLAND 515 GmbH Methods and devices for treating vulnerable plaque
US10278947B2 (en) 2007-02-28 2019-05-07 Orthopeutics, L.P. Crosslinker enhanced repair of connective tissues
ES2402334T3 (es) 2007-08-02 2013-04-30 Gilead Biologics, Inc Procedimientos y composiciones para el tratamiento y el diagnóstico de la fibrosis
US9107935B2 (en) * 2009-01-06 2015-08-18 Gilead Biologics, Inc. Chemotherapeutic methods and compositions
CN102711821A (zh) * 2009-08-21 2012-10-03 吉联亚生物科技有限公司 治疗方法和组合物
US20110207144A1 (en) * 2009-08-21 2011-08-25 Derek Marshall In vitro screening assays
WO2011022670A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vivo screening assays
SG178845A1 (en) 2009-08-21 2012-04-27 Gilead Biologics Inc Catalytic domains from lysyl oxidase and loxl2
CN102711820A (zh) * 2009-08-21 2012-10-03 吉联亚生物科技有限公司 治疗肺纤维化疾病的方法和组合物
BR112012019693A2 (pt) 2010-02-04 2017-06-20 Gilead Biologics Inc anticorpos que se ligam à lisil oxidase-like 2 (loxl2) e métodos de uso para eles.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834213A (en) * 1991-05-02 1998-11-10 Baylor College Of Medicine Screening system and assay for identifying compounds that regulate steroid and orphan receptors mediation of DNA transcription
HUP0104719A3 (en) 1998-12-18 2004-03-01 Wyeth Corp Bioassay for identifying estrogen receptor-betha/alfa selective modulators
AU4073600A (en) 1999-04-09 2000-11-14 Human Genome Sciences, Inc. Bone morphogenic proteins
US7264926B2 (en) * 2000-04-18 2007-09-04 Millennium Pharmaceuticals, Inc. Nucleoside Phosphatase
WO2001083702A2 (en) * 2000-05-03 2001-11-08 University Of Hawaii Novel members of the lysyl oxidases family of amine oxidases related applications
WO2001092495A2 (en) 2000-05-26 2001-12-06 Millennium Pharmaceuticals, Inc. A human lysyl ixodase (47765) and uses thereof

Also Published As

Publication number Publication date
HK1060148A1 (en) 2004-07-30
WO2002012470A2 (en) 2002-02-14
AU2001284769A1 (en) 2002-02-18
DE60128830D1 (de) 2007-07-19
CA2418952A1 (en) 2002-02-14
BR0113257A (pt) 2003-10-28
US20040171110A1 (en) 2004-09-02
WO2002012470A3 (en) 2003-08-28
EP1354046A2 (de) 2003-10-22
IL154036A0 (en) 2003-07-31
JP2004505631A (ja) 2004-02-26
DE60128830T2 (de) 2008-01-31
US20020102645A1 (en) 2002-08-01
US7208300B2 (en) 2007-04-24
EP1354046B1 (de) 2007-06-06
MXPA03001196A (es) 2004-04-05
US7445920B2 (en) 2008-11-04

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