ATE364706T1 - Nukleotid- und proteinsequenz von mammastatin und anwendungsmethoden - Google Patents
Nukleotid- und proteinsequenz von mammastatin und anwendungsmethodenInfo
- Publication number
- ATE364706T1 ATE364706T1 AT98964170T AT98964170T ATE364706T1 AT E364706 T1 ATE364706 T1 AT E364706T1 AT 98964170 T AT98964170 T AT 98964170T AT 98964170 T AT98964170 T AT 98964170T AT E364706 T1 ATE364706 T1 AT E364706T1
- Authority
- AT
- Austria
- Prior art keywords
- mammastatin
- kda
- phosphorylated
- mammary
- express
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/994,076 US6500937B1 (en) | 1996-10-03 | 1997-12-19 | Nucleotide sequence encoding a mammary cell growth inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE364706T1 true ATE364706T1 (de) | 2007-07-15 |
Family
ID=25540260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98964170T ATE364706T1 (de) | 1997-12-19 | 1998-12-18 | Nukleotid- und proteinsequenz von mammastatin und anwendungsmethoden |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US6500937B1 (de) |
| EP (1) | EP1037989B1 (de) |
| JP (1) | JP4441113B2 (de) |
| AT (1) | ATE364706T1 (de) |
| AU (1) | AU1935399A (de) |
| CA (1) | CA2315239C (de) |
| DE (1) | DE69837935T2 (de) |
| WO (1) | WO1999032625A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6500937B1 (en) * | 1996-10-03 | 2002-12-31 | University Of Michigan | Nucleotide sequence encoding a mammary cell growth inhibitor |
| BR9713248A (pt) * | 1996-10-03 | 2000-01-18 | Biotherapies Inc | Sequência de nucleotìdeos e de proteìnas de mamastatina e processos de uso |
| IL147148A0 (en) * | 1999-06-18 | 2002-08-14 | Biotherapies Inc | Epithelial cell growth inhibitors |
| US6939714B2 (en) | 1999-06-18 | 2005-09-06 | Biotherapies, Inc. | Epithelial cell growth inhibitors |
| WO2001013117A2 (en) * | 1999-08-13 | 2001-02-22 | Oxford Glycosciences (Uk) Limited | Proteins, genes and their use for diagnosis and treatment of breast cancer |
| AU2596901A (en) * | 1999-12-21 | 2001-07-03 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| EP1266225A2 (de) * | 2000-03-20 | 2002-12-18 | Oxford GlycoSciences (UK) Limited | Diagnose und behandlung von brustkrebs |
| US20030212263A1 (en) * | 2000-06-19 | 2003-11-13 | The University Of Michigan | Mammastatin sequence variant C |
| WO2002088750A2 (en) * | 2001-05-02 | 2002-11-07 | Oxford Glycosciences (Uk) Ltd | Proteins, genes and their use for diagnosis and treatment of breast cancer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4379839A (en) | 1977-05-23 | 1983-04-12 | The Trustees Of Columbia University In The City Of New York | Method for detecting cancer |
| US4753894A (en) | 1984-02-08 | 1988-06-28 | Cetus Corporation | Monoclonal anti-human breast cancer antibodies |
| JPH05506351A (ja) | 1988-05-20 | 1993-09-22 | ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン | ヒト乳房細胞成長インヒビターに対する抗体ならびにその製造方法および使用 |
| JPH05506423A (ja) | 1988-05-20 | 1993-09-22 | ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン | ヒト乳房細胞成長インヒビターならびにその製造方法および使用 |
| US5878385A (en) * | 1996-09-16 | 1999-03-02 | Ergo Linguistic Technologies | Method and apparatus for universal parsing of language |
| US6500937B1 (en) | 1996-10-03 | 2002-12-31 | University Of Michigan | Nucleotide sequence encoding a mammary cell growth inhibitor |
| BR9713248A (pt) * | 1996-10-03 | 2000-01-18 | Biotherapies Inc | Sequência de nucleotìdeos e de proteìnas de mamastatina e processos de uso |
| IL147148A0 (en) | 1999-06-18 | 2002-08-14 | Biotherapies Inc | Epithelial cell growth inhibitors |
-
1997
- 1997-12-19 US US08/994,076 patent/US6500937B1/en not_active Expired - Fee Related
-
1998
- 1998-12-18 DE DE69837935T patent/DE69837935T2/de not_active Expired - Lifetime
- 1998-12-18 EP EP98964170A patent/EP1037989B1/de not_active Expired - Lifetime
- 1998-12-18 WO PCT/US1998/027147 patent/WO1999032625A2/en not_active Ceased
- 1998-12-18 CA CA002315239A patent/CA2315239C/en not_active Expired - Fee Related
- 1998-12-18 JP JP2000525544A patent/JP4441113B2/ja not_active Expired - Fee Related
- 1998-12-18 AT AT98964170T patent/ATE364706T1/de not_active IP Right Cessation
- 1998-12-18 AU AU19353/99A patent/AU1935399A/en not_active Abandoned
-
2000
- 2000-08-22 US US09/643,476 patent/US6599495B1/en not_active Expired - Fee Related
-
2003
- 2003-06-11 US US10/459,218 patent/US7256277B2/en not_active Expired - Fee Related
-
2007
- 2007-08-14 US US11/838,654 patent/US7816097B2/en not_active Expired - Fee Related
-
2010
- 2010-07-29 US US12/846,386 patent/US20110003318A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69837935D1 (de) | 2007-07-26 |
| US6599495B1 (en) | 2003-07-29 |
| EP1037989A2 (de) | 2000-09-27 |
| CA2315239A1 (en) | 1999-07-01 |
| EP1037989B1 (de) | 2007-06-13 |
| US20080207506A1 (en) | 2008-08-28 |
| US20110003318A1 (en) | 2011-01-06 |
| US7256277B2 (en) | 2007-08-14 |
| WO1999032625A2 (en) | 1999-07-01 |
| US20070082334A1 (en) | 2007-04-12 |
| CA2315239C (en) | 2008-05-13 |
| JP2001526891A (ja) | 2001-12-25 |
| US6500937B1 (en) | 2002-12-31 |
| JP4441113B2 (ja) | 2010-03-31 |
| WO1999032625A3 (en) | 1999-09-16 |
| DE69837935T2 (de) | 2008-02-21 |
| US7816097B2 (en) | 2010-10-19 |
| AU1935399A (en) | 1999-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |