ATE364710T1 - Rekombinante mikroorganismen für die produktion von vitamin b6 - Google Patents
Rekombinante mikroorganismen für die produktion von vitamin b6Info
- Publication number
- ATE364710T1 ATE364710T1 AT03748056T AT03748056T ATE364710T1 AT E364710 T1 ATE364710 T1 AT E364710T1 AT 03748056 T AT03748056 T AT 03748056T AT 03748056 T AT03748056 T AT 03748056T AT E364710 T1 ATE364710 T1 AT E364710T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- phosphate
- production
- erythrose
- recombinant microorganisms
- Prior art date
Links
- 244000005700 microbiome Species 0.000 title abstract 3
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- 108030004509 Erythrose-4-phosphate dehydrogenases Proteins 0.000 abstract 3
- 108010060155 deoxyxylulose-5-phosphate synthase Proteins 0.000 abstract 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 abstract 2
- WHOMFKWHIQZTHY-UHFFFAOYSA-L pyridoxine 5'-phosphate(2-) Chemical compound CC1=NC=C(COP([O-])([O-])=O)C(CO)=C1O WHOMFKWHIQZTHY-UHFFFAOYSA-L 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 abstract 1
- 239000011726 vitamin B6 Substances 0.000 abstract 1
- 235000019158 vitamin B6 Nutrition 0.000 abstract 1
- 229940011671 vitamin b6 Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02021623 | 2002-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE364710T1 true ATE364710T1 (de) | 2007-07-15 |
Family
ID=32039107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03748056T ATE364710T1 (de) | 2002-09-27 | 2003-09-18 | Rekombinante mikroorganismen für die produktion von vitamin b6 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060228785A1 (de) |
| EP (1) | EP1543139B1 (de) |
| CN (1) | CN100441681C (de) |
| AT (1) | ATE364710T1 (de) |
| AU (1) | AU2003267385A1 (de) |
| DE (1) | DE60314430T2 (de) |
| WO (1) | WO2004029271A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103857786B (zh) * | 2011-07-29 | 2016-04-06 | 庆尚大学校产学协力团 | 从微生物中制造类视黄醇的方法 |
| KR20140147982A (ko) * | 2013-06-20 | 2014-12-31 | 경상대학교산학협력단 | 레티노이드 생산에 관여하는 효소를 코딩하는 유전자를 포함하는 미생물 및 이를 이용한 레티노이드의 생산 방법 |
| CN112375725B (zh) * | 2021-01-18 | 2021-03-30 | 中国科学院天津工业生物技术研究所 | 一种生产维生素b6的代谢工程菌株及其构建方法与应用 |
| CN114657159B (zh) * | 2022-05-24 | 2022-08-23 | 中国科学院天津工业生物技术研究所 | 4-磷酸羟基-L-苏氨酸脱氢酶PdxA突变体及其在制备维生素B 6中的应用 |
| CN116286692B (zh) * | 2022-08-26 | 2025-10-31 | 中国科学院天津工业生物技术研究所 | 赤藓糖-4-磷酸脱氢酶突变体及其编码基因在生产维生素b6中的应用 |
| CN117165615A (zh) * | 2023-09-25 | 2023-12-05 | 江南大学 | 一种通过调节胞内plp供给提高1,5-戊二胺从头合成能力的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0950715A3 (de) * | 1998-04-15 | 2001-07-25 | F. Hoffmann-La Roche Ag | Enzymatische Herstellung von Vitamin B6 |
-
2003
- 2003-09-18 DE DE60314430T patent/DE60314430T2/de not_active Expired - Fee Related
- 2003-09-18 AU AU2003267385A patent/AU2003267385A1/en not_active Abandoned
- 2003-09-18 US US10/528,891 patent/US20060228785A1/en not_active Abandoned
- 2003-09-18 CN CNB038226146A patent/CN100441681C/zh not_active Expired - Fee Related
- 2003-09-18 AT AT03748056T patent/ATE364710T1/de not_active IP Right Cessation
- 2003-09-18 WO PCT/EP2003/010403 patent/WO2004029271A1/en not_active Ceased
- 2003-09-18 EP EP03748056A patent/EP1543139B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1685051A (zh) | 2005-10-19 |
| DE60314430D1 (de) | 2007-07-26 |
| EP1543139A1 (de) | 2005-06-22 |
| US20060228785A1 (en) | 2006-10-12 |
| EP1543139B1 (de) | 2007-06-13 |
| AU2003267385A1 (en) | 2004-04-19 |
| DE60314430T2 (de) | 2008-02-07 |
| CN100441681C (zh) | 2008-12-10 |
| WO2004029271A1 (en) | 2004-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |