ATE365042T1 - Verwendung von morpholinol zur behandlung von sexuellen funktionsstörungen - Google Patents

Verwendung von morpholinol zur behandlung von sexuellen funktionsstörungen

Info

Publication number: ATE365042T1
Authority: AT; Austria
Prior art keywords: morpholinol; sexual disorders; treat sexual; treat; disorders
Prior art date: 1998-01-21

Application number

AT99903200T

Other languages

English (en)

Inventor

Phillip Morgan

David Musso

John Partridge

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-21

Filing date

1999-01-20

Publication date

2007-07-15

1998-01-21 Priority claimed from GBGB9801230.5A external-priority patent/GB9801230D0/en

1999-01-20 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2007-07-15 Application granted granted Critical

2007-07-15 Publication of ATE365042T1 publication Critical patent/ATE365042T1/de

Links

OURXRFYZEOUCRM-UHFFFAOYSA-N 4-hydroxymorpholine Chemical compound ON1CCOCC1 OURXRFYZEOUCRM-UHFFFAOYSA-N 0.000 title 1
230000001568 sexual effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT99903200T 1998-01-21 1999-01-20 Verwendung von morpholinol zur behandlung von sexuellen funktionsstörungen ATE365042T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9801230.5A GB9801230D0 (en)	1998-01-21	1998-01-21	Pharmaceutically active morpholinol
US7218098P	1998-01-22	1998-01-22

Publications (1)

Publication Number	Publication Date
ATE365042T1 true ATE365042T1 (de)	2007-07-15

Family

ID=26312986

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99903200T ATE365042T1 (de)	1998-01-21	1999-01-20	Verwendung von morpholinol zur behandlung von sexuellen funktionsstörungen

Country Status (30)

Country	Link
US (2)	US6274579B1 (de)
EP (2)	EP1047428B1 (de)
JP (1)	JP2002501025A (de)
KR (1)	KR100568063B1 (de)
CN (2)	CN1203858C (de)
AP (1)	AP1229A (de)
AT (1)	ATE365042T1 (de)
AU (1)	AU755536B2 (de)
BR (1)	BR9907203A (de)
CA (1)	CA2318268A1 (de)
CY (1)	CY1106828T1 (de)
DE (1)	DE69936335T2 (de)
DK (1)	DK1047428T3 (de)
EA (1)	EA002410B1 (de)
EE (1)	EE04452B1 (de)
ES (1)	ES2288012T3 (de)
HR (2)	HRP20051024A2 (de)
HU (1)	HUP0100900A3 (de)
ID (1)	ID26334A (de)
IL (2)	IL161942A0 (de)
IS (1)	IS2494B (de)
NO (2)	NO326878B1 (de)
NZ (3)	NZ520349A (de)
PL (1)	PL193622B1 (de)
PT (1)	PT1047428E (de)
SG (1)	SG115489A1 (de)
SK (1)	SK10912000A3 (de)
TR (1)	TR200002126T2 (de)
WO (1)	WO1999037305A1 (de)
YU (1)	YU67102A (de)

Families Citing this family (42)

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US7098206B2 (en) *	1998-01-21	2006-08-29	Smithkline Beecham Corporation	Pharmaceutically active morpholinol
US6998400B2 (en)	1998-01-22	2006-02-14	Smithkline Beecham Corporation	Pharmaceutically active morpholinol
AU2483599A (en)	1998-01-29	1999-08-16	Sepracor, Inc.	Pharmaceutical uses of optically pure (-)-bupropion
AU2349999A (en) *	1998-01-29	1999-08-16	Sepracor, Inc.	Pharmacological uses of pure (+) -bupropion
US6855820B2 (en)	1999-01-20	2005-02-15	Smithkline Beecham Corporation	Pharmaceutically active morpholinol
US6734213B2 (en)	1999-01-20	2004-05-11	Smithkline Beecham Corporation	Pharmaceutically active morpholinol
US6337328B1 (en) *	1999-03-01	2002-01-08	Sepracor, Inc.	Bupropion metabolites and methods of use
US6342496B1 (en)	1999-03-01	2002-01-29	Sepracor Inc.	Bupropion metabolites and methods of use
EP1220673A2 (de) *	1999-10-13	2002-07-10	Glaxo Group Limited	Morpholinol-verbindungen zur behandlung von fettleibigkeit
GB0003232D0 (en) *	2000-02-11	2000-04-05	Smithkline Beecham Plc	Novel composition
US7145649B2 (en) *	2000-12-21	2006-12-05	Brasscorp Limited	Method of producing an ultra-violet or near ultra-violet light source for non-destructive inspection or testing
US6979104B2 (en)	2001-12-31	2005-12-27	R.J. Doran & Co. LTD	LED inspection lamp
EP3173082A1 (de)	2002-05-17	2017-05-31	Duke University	Verfahren zur behandlung von adipositas
US20050215552A1 (en) *	2002-05-17	2005-09-29	Gadde Kishore M	Method for treating obesity
GB0219687D0 (en) *	2002-08-23	2002-10-02	Lilly Co Eli	Benzyl morpholine derivatives
WO2004017977A2 (en) *	2002-08-23	2004-03-04	Eli Lilly And Company	2- (phenoxymethyl)- and 2- (phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors
HUE034290T2 (en)	2003-04-29	2018-02-28	Orexigen Therapeutics Inc	Preparations containing opioid antagonist and bupropion to affect weight loss
US20070093486A1 (en) *	2003-10-27	2007-04-26	Smith Kline Beecham Corporation ,Corporation	Enzyme-catalyzed dynamic kinetic resolution process for preparing (+)-(2s,3s)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinoland salts and solvates thereof
GB0325055D0 (en) *	2003-10-27	2003-12-03	Smithkline Beecham Corp	New process
GB0326148D0 (en) *	2003-11-10	2003-12-17	Lilly Co Eli	Morpholine derivatives
GB0327195D0 (en) *	2003-11-21	2003-12-24	Smithkline Beecham Corp	Novel use
GB0327619D0 (en) *	2003-11-27	2003-12-31	Smithkline Beecham Corp	New use
US7429580B2 (en) *	2004-01-13	2008-09-30	Orexigen Therapeutics, Inc.	Compositions of an anticonvulsant and an antipsychotic drug and methods of using the same for affecting weight loss
US7713959B2 (en) *	2004-01-13	2010-05-11	Duke University	Compositions of an anticonvulsant and mirtazapine to prevent weight gain
RU2006139930A (ru) *	2004-05-03	2008-06-10	Дюк Юниверсити (Сша/Сша) (Us)	Составы для содействия снижению веса
FI117283B (fi)	2005-02-04	2006-08-31	Kone Corp	Hissijärjestelmä
CA2630624C (en)	2005-11-22	2013-08-06	Orexigen Therapeutics, Inc.	Compositions and methods for increasing insulin sensitivity
CA2635261A1 (en) *	2006-01-03	2007-07-12	Algebra, Inc.	Therapeutic amine-arylsulfonamide conjugate compounds
US8916195B2 (en)	2006-06-05	2014-12-23	Orexigen Therapeutics, Inc.	Sustained release formulation of naltrexone
KR20170077291A (ko)	2006-11-09	2017-07-05	오렉시젠 세러퓨틱스 인크.	단위 용량 팩키지
TWI609702B (zh)	2006-11-09	2018-01-01	歐瑞根治療有限公司	層狀醫藥調配物
US20090075994A1 (en) *	2007-09-14	2009-03-19	Protia, Llc	Deuterium-enriched radafaxine
JP2011521973A (ja)	2008-05-30	2011-07-28	オレキシジェン・セラピューティクス・インコーポレーテッド	内臓脂肪の状態を処置するための方法
EP2419400A1 (de)	2009-04-15	2012-02-22	Research Triangle Institute	Monoaminwiederaufnahmehemmer
ES2762113T3 (es)	2010-01-11	2020-05-22	Nalpropion Pharmaceuticals Inc	Métodos de proporcionar terapia de pérdida de peso en pacientes con depresión mayor
JP2013526583A (ja)	2010-05-21	2013-06-24	リサーチ・トライアングル・インスティチュート	フェニルモルホリンおよびその類似体
CA2800219C (en)	2010-05-21	2019-03-12	Research Triangle Institute	1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
US9510405B2 (en)	2011-06-30	2016-11-29	Schneider Electric Industries Sas	Dual power SMPS for a modular lighting system
CN102670617B (zh) *	2012-04-13	2013-03-20	湖南大学	布洛芬2-（2-芳基吗啉-4-基）乙酯作为制备抗抑郁药物的应用
LT3730132T (lt)	2012-06-06	2022-08-25	Nalpropion Pharmaceuticals Llc	Kompozicija, skirta panaudoti pacientų su didele širdies ir kraujagyslių ligų rizika antsvorio ir nutukimo gydymo būde
CN105949142B (zh) *	2016-05-21	2018-03-27	南华大学	具有抗抑郁活性的单一手性化合物及其制备方法和应用
RU2763728C1 (ru) *	2021-06-17	2021-12-30	Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ)	Применение 3-(2-(4-нитрофенил)-2-оксоэтилиден)морфолин-2-она в качестве средства, обладающего противомикробной активностью

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US170430A (en) *		1875-11-30		Improvement in furnaces for heating steel in tempering
GB8417170D0 (en) *	1984-07-05	1984-08-08	Wellcome Found	Heterocyclic pharmaceutical compounds
GB9108629D0 (en)	1991-04-23	1991-06-12	Wellcome Found	Heterocyclic pharmaceutical compounds,preparation and use
US6337328B1 (en)	1999-03-01	2002-01-08	Sepracor, Inc.	Bupropion metabolites and methods of use

1999
- 1999-01-20 PL PL99342012A patent/PL193622B1/pl not_active IP Right Cessation
- 1999-01-20 US US09/233,531 patent/US6274579B1/en not_active Expired - Fee Related
- 1999-01-20 AU AU23280/99A patent/AU755536B2/en not_active Ceased
- 1999-01-20 EP EP99903200A patent/EP1047428B1/de not_active Expired - Lifetime
- 1999-01-20 SK SK1091-2000A patent/SK10912000A3/sk unknown
- 1999-01-20 WO PCT/US1999/001134 patent/WO1999037305A1/en not_active Ceased
- 1999-01-20 IL IL16194299A patent/IL161942A0/xx unknown
- 1999-01-20 IL IL13734699A patent/IL137346A0/xx not_active IP Right Cessation
- 1999-01-20 NZ NZ520349A patent/NZ520349A/en unknown
- 1999-01-20 CA CA002318268A patent/CA2318268A1/en not_active Abandoned
- 1999-01-20 HR HR20051024A patent/HRP20051024A2/hr not_active Application Discontinuation
- 1999-01-20 ES ES99903200T patent/ES2288012T3/es not_active Expired - Lifetime
- 1999-01-20 CN CNB998042706A patent/CN1203858C/zh not_active Expired - Fee Related
- 1999-01-20 JP JP2000528287A patent/JP2002501025A/ja active Pending
- 1999-01-20 NZ NZ505809A patent/NZ505809A/xx unknown
- 1999-01-20 SG SG200204411A patent/SG115489A1/en unknown
- 1999-01-20 PT PT99903200T patent/PT1047428E/pt unknown
- 1999-01-20 NZ NZ529316A patent/NZ529316A/en unknown
- 1999-01-20 DK DK99903200T patent/DK1047428T3/da active
- 1999-01-20 EP EP07110283A patent/EP1829544A1/de not_active Withdrawn
- 1999-01-20 DE DE69936335T patent/DE69936335T2/de not_active Expired - Lifetime
- 1999-01-20 HR HR20000494A patent/HRP20000494B1/xx not_active IP Right Cessation
- 1999-01-20 BR BR9907203-3A patent/BR9907203A/pt not_active Application Discontinuation
- 1999-01-20 AP APAP/P/2000/001869A patent/AP1229A/en active
- 1999-01-20 HU HU0100900A patent/HUP0100900A3/hu unknown
- 1999-01-20 CN CNB2004100085595A patent/CN1255389C/zh not_active Expired - Fee Related
- 1999-01-20 EE EEP200000438A patent/EE04452B1/xx not_active IP Right Cessation
- 1999-01-20 ID IDW20001597A patent/ID26334A/id unknown
- 1999-01-20 AT AT99903200T patent/ATE365042T1/de active
- 1999-01-20 KR KR1020007007996A patent/KR100568063B1/ko not_active Expired - Fee Related
- 1999-01-20 TR TR2000/02126T patent/TR200002126T2/xx unknown
- 1999-01-20 EA EA200000691A patent/EA002410B1/ru not_active IP Right Cessation
2000
- 2000-07-20 NO NO20003721A patent/NO326878B1/no not_active IP Right Cessation
- 2000-07-20 IS IS5568A patent/IS2494B/is unknown
2001
- 2001-06-22 US US09/886,391 patent/US6391875B2/en not_active Expired - Fee Related
2002
- 2002-09-06 YU YU67102A patent/YU67102A/sh unknown
2007
- 2007-08-31 CY CY20071101117T patent/CY1106828T1/el unknown
2008
- 2008-08-14 NO NO20083529A patent/NO20083529L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
YU67102A (sh)	2004-12-31
JP2002501025A (ja)	2002-01-15
HUP0100900A3 (en)	2002-08-28
AP1229A (en)	2003-12-04
IS2494B (is)	2009-02-15
HRP20000494A2 (en)	2000-12-31
EE04452B1 (et)	2005-04-15
WO1999037305A1 (en)	1999-07-29
AU755536B2 (en)	2002-12-12
CN1255389C (zh)	2006-05-10
DK1047428T3 (da)	2007-10-08
BR9907203A (pt)	2000-10-17
CN1294513A (zh)	2001-05-09
HUP0100900A2 (hu)	2002-05-29
ID26334A (id)	2000-12-14
TR200002126T2 (tr)	2000-12-21
EA002410B1 (ru)	2002-04-25
AP2000001869A0 (en)	2000-09-30
SK10912000A3 (sk)	2001-04-09
EP1829544A1 (de)	2007-09-05
KR20010034285A (ko)	2001-04-25
IL161942A0 (en)	2005-11-20
US6274579B1 (en)	2001-08-14
CA2318268A1 (en)	1999-07-29
US6391875B2 (en)	2002-05-21
EP1047428A1 (de)	2000-11-02
EA200000691A1 (ru)	2001-04-23
SG115489A1 (en)	2005-10-28
AU2328099A (en)	1999-08-09
CN1203858C (zh)	2005-06-01
US20020019396A1 (en)	2002-02-14
CN1528753A (zh)	2004-09-15
IL137346A0 (en)	2001-07-24
HRP20051024A2 (hr)	2006-04-30
NZ529316A (en)	2004-05-28
EP1047428A4 (de)	2001-12-19
ES2288012T3 (es)	2007-12-16
HRP20000494B1 (en)	2009-02-28
NZ520349A (en)	2004-02-27
NO20083529L (no)	2000-09-19
EP1047428B1 (de)	2007-06-20
KR100568063B1 (ko)	2006-04-07
NZ505809A (en)	2002-09-27
DE69936335T2 (de)	2008-02-28
DE69936335D1 (de)	2007-08-02
PT1047428E (pt)	2007-09-07
CY1106828T1 (el)	2012-05-23
NO20003721D0 (no)	2000-07-20
NO20003721L (no)	2000-09-19
PL342012A1 (en)	2001-05-07
NO326878B1 (no)	2009-03-09
PL193622B1 (pl)	2007-02-28
EE200000438A (et)	2001-12-17
IS5568A (is)	2000-07-20

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2007-10-15

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ATE365042T1 (de)	2007-07-15	Verwendung von morpholinol zur behandlung von sexuellen funktionsstörungen
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