ATE369351T1 - Enantiomere verbindungen zur behandlung von herzrythmusstörungen und verfahren zu ihrer anwendung - Google Patents

Enantiomere verbindungen zur behandlung von herzrythmusstörungen und verfahren zu ihrer anwendung

Info

Publication number
ATE369351T1
ATE369351T1 AT00972216T AT00972216T ATE369351T1 AT E369351 T1 ATE369351 T1 AT E369351T1 AT 00972216 T AT00972216 T AT 00972216T AT 00972216 T AT00972216 T AT 00972216T AT E369351 T1 ATE369351 T1 AT E369351T1
Authority
AT
Austria
Prior art keywords
compounds
treatment
cardiac
arthry
disorders
Prior art date
Application number
AT00972216T
Other languages
English (en)
Inventor
Pascal Druzgala
Peter Milner
Original Assignee
Aryx Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/680,873 external-priority patent/US6372783B1/en
Application filed by Aryx Therapeutics filed Critical Aryx Therapeutics
Application granted granted Critical
Publication of ATE369351T1 publication Critical patent/ATE369351T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00972216T 1999-10-15 2000-10-13 Enantiomere verbindungen zur behandlung von herzrythmusstörungen und verfahren zu ihrer anwendung ATE369351T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15960999P 1999-10-15 1999-10-15
US09/680,873 US6372783B1 (en) 1999-10-15 2000-10-06 Enantiomeric compounds for treatment of cardiac arrhythmias and methods of use
US09/684,046 US6362223B1 (en) 1999-10-15 2000-10-06 Enantiomeric compounds for treatment of cardiac arrhythmias and methods of use

Publications (1)

Publication Number Publication Date
ATE369351T1 true ATE369351T1 (de) 2007-08-15

Family

ID=27388333

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00972216T ATE369351T1 (de) 1999-10-15 2000-10-13 Enantiomere verbindungen zur behandlung von herzrythmusstörungen und verfahren zu ihrer anwendung

Country Status (11)

Country Link
EP (1) EP1222180B1 (de)
JP (1) JP4684514B2 (de)
AT (1) ATE369351T1 (de)
AU (1) AU774873B2 (de)
CA (1) CA2392016C (de)
DE (1) DE60035888T2 (de)
DK (1) DK1222180T3 (de)
ES (1) ES2290054T3 (de)
HK (1) HK1049829B (de)
PT (1) PT1222180E (de)
WO (1) WO2001029018A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002038557A2 (en) * 1993-06-16 2002-05-16 Aryx Therapeutics Benzoylbenzofurane derivatives for treatment of cardiac arrhythmia
AU2002211479B2 (en) * 2000-10-06 2007-08-30 Aryx Therapeutics Benzoylbenzofurane derivatives for treatment of cardiac arrhythmia
DE10129119B4 (de) * 2001-06-16 2007-10-04 Schwarz Pharma Ag Kristalline Salze von Benzoylbenzofuran-Derivaten, insbesondere von[2-(4-{1-[2-((S)-sec.-Butoxycarbonylmethyl)-benzofuran-3-carbonyl]-methanoyl}-2,6-diiod-phenoxy)-ethyl]-diethylamino und [2-(4-{1-[(3-Methyl-2-(S)-Butoxycarbonylmethyl)-benzofuran-3-carbonyl]- methanoyl}-2,6-diiodphenoxy)-ethyl]-diethylamino, deren Verwendung und Herstellung sowie diese Salze enthaltende Arzneimittel
AU2005232701A1 (en) * 2004-04-09 2005-10-27 Aryx Therapeutics Benzofuranyl derivatives useful for the treatment of cardiac arrhytmia
EP2145881A1 (de) 2005-07-15 2010-01-20 Aryx Therapeutics, Inc. Antiarrhythmische Vorläuferverbindungen, Syntheseverfahren und Verwendungsverfahren
WO2010059119A1 (en) * 2008-11-21 2010-05-27 Astrazeneca Ab A combination of tert -butyl (2-{7- [2- (4-cyano-2- f luorophenoxy) ethyl] -9-oxa-3, 7-diazabicyclo [3.3.1] non-3- yl } ethyl) carbamate and certain antiarrhythmic benzofurans

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364880A (en) * 1993-06-16 1994-11-15 Advanced Therapies, Inc. Compound for treatment of cardiac arrhythmia, synthesis, and methods of use

Also Published As

Publication number Publication date
EP1222180B1 (de) 2007-08-08
HK1049829A1 (en) 2003-05-30
WO2001029018A3 (en) 2001-11-29
JP2003512364A (ja) 2003-04-02
AU774873B2 (en) 2004-07-08
DK1222180T3 (da) 2007-12-27
CA2392016A1 (en) 2001-04-26
ES2290054T3 (es) 2008-02-16
PT1222180E (pt) 2007-09-20
AU1091201A (en) 2001-04-30
HK1049829B (en) 2008-02-22
JP4684514B2 (ja) 2011-05-18
DE60035888T2 (de) 2007-12-06
CA2392016C (en) 2010-04-13
EP1222180A2 (de) 2002-07-17
DE60035888D1 (de) 2007-09-20
WO2001029018A2 (en) 2001-04-26

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