ATE369845T1 - Behandlung der nebenwirkungen von statinen - Google Patents
Behandlung der nebenwirkungen von statinenInfo
- Publication number
- ATE369845T1 ATE369845T1 AT01998341T AT01998341T ATE369845T1 AT E369845 T1 ATE369845 T1 AT E369845T1 AT 01998341 T AT01998341 T AT 01998341T AT 01998341 T AT01998341 T AT 01998341T AT E369845 T1 ATE369845 T1 AT E369845T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- relates
- side effects
- uridine
- therapy
- Prior art date
Links
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title abstract 3
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title 1
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 abstract 6
- 238000002560 therapeutic procedure Methods 0.000 abstract 4
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 abstract 3
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 abstract 3
- 235000017471 coenzyme Q10 Nutrition 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 abstract 3
- 229940045145 uridine Drugs 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 Coenzyme Q10 (Q10) Chemical compound 0.000 abstract 1
- 206010049565 Muscle fatigue Diseases 0.000 abstract 1
- 208000000112 Myalgia Diseases 0.000 abstract 1
- 150000004054 benzoquinones Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 abstract 1
- 229940110767 coenzyme Q10 Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000013465 muscle pain Diseases 0.000 abstract 1
- SOECUQMRSRVZQQ-UHFFFAOYSA-N ubiquinone-1 Chemical compound COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O SOECUQMRSRVZQQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Preparations (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR1773A AUPR177300A0 (en) | 2000-11-29 | 2000-11-29 | Therapeutic methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE369845T1 true ATE369845T1 (de) | 2007-09-15 |
Family
ID=3825810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01998341T ATE369845T1 (de) | 2000-11-29 | 2001-11-29 | Behandlung der nebenwirkungen von statinen |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20040063661A1 (de) |
| EP (1) | EP1343488B1 (de) |
| JP (2) | JP4596734B2 (de) |
| AT (1) | ATE369845T1 (de) |
| AU (3) | AUPR177300A0 (de) |
| CA (1) | CA2429979C (de) |
| DE (1) | DE60130023T2 (de) |
| ES (1) | ES2292643T3 (de) |
| NZ (1) | NZ526069A (de) |
| WO (1) | WO2002043721A1 (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR951101A0 (en) * | 2001-12-13 | 2002-01-24 | Centre For Molecular Biology And Medicine | Method of treatment |
| DK1641444T3 (en) * | 2003-06-02 | 2016-06-27 | Isis Innovation | Treatment of muscle fatigue |
| AU2004245567B2 (en) | 2003-06-03 | 2011-06-23 | Oxford University Innovation Limited | Nutritional supplements and therapeutic compositions comprising (R)-3-hydroxybutyrate derivatives |
| CA3031283A1 (en) | 2004-01-22 | 2005-08-04 | University Of Miami | Topical co-enzyme q10 formulations and methods of use |
| US20050288378A1 (en) * | 2004-06-21 | 2005-12-29 | Xiaoqiang Yan | Cancer chemotherapy |
| US20050288379A1 (en) * | 2004-06-21 | 2005-12-29 | Xiaoqiang Yan | Benzoquinone compounds as anti-cancer agents |
| WO2006057209A1 (ja) * | 2004-11-26 | 2006-06-01 | Sankyo Company, Limited | 血中遊離脂肪酸低下作用を有する医薬組成物 |
| JP4896501B2 (ja) * | 2004-11-26 | 2012-03-14 | 第一三共株式会社 | 血中遊離脂肪酸低下作用を有する医薬組成物 |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| PT2471530T (pt) | 2005-06-01 | 2017-04-19 | Edison Pharmaceuticals Inc | Produtos terapêuticos com atividade redox para o tratamento de doenças mitocondriais e de outras condições e modulação de biomarcadores energéticos |
| EP1991241A4 (de) * | 2006-02-23 | 2009-07-08 | Iomedix Sleep Internat Srl | Zusammensetzungen und verfahren zur einleitung und aufrechterhaltung von hochwertigem schlaf |
| US20070286906A1 (en) * | 2006-04-28 | 2007-12-13 | Hutchison Medipharma Enterprises Limited | Dihydrobenzoquinone compounds |
| EP3173068B1 (de) * | 2006-05-02 | 2020-09-09 | University of Miami | Topische co-enzym-q10-formulierungen und behandlung von wunden |
| ES2730879T3 (es) | 2008-01-04 | 2019-11-13 | Univ Oxford Innovation Ltd | Cuerpos de cetona y ésteres de cuerpos de cetona como agentes reductores de lípidos de la sangre |
| CA2716020C (en) | 2008-02-29 | 2018-10-16 | Biolab Sanus Farmaceutica Ltda. | Pharmaceutical compositions comprising piracetam and l-carnitine |
| AU2009233785B2 (en) | 2008-04-11 | 2015-08-20 | Berg Llc | Methods and use of inducing apoptosis in cancer cells |
| US8642654B2 (en) | 2009-04-16 | 2014-02-04 | Isis Innovation Limited | Hydroxybutyrate ester and medical use thereof |
| US8314153B2 (en) | 2008-09-10 | 2012-11-20 | Edison Pharmaceuticals, Inc. | Treatment of pervasive developmental disorders with redox-active therapeutics |
| JP5426918B2 (ja) * | 2009-04-20 | 2014-02-26 | 株式会社 伊藤園 | ウリジンを含有する抗疲労剤又は体力向上剤 |
| BRPI1010576A2 (pt) | 2009-05-11 | 2016-03-15 | Berg Biosystems Llc | métodos para tratamento de distúrbios oncológicos usando transferidores epimetabólicos, moléculas intracelulares multidimensionais ou influenciadores ambientais. |
| US8557236B2 (en) * | 2010-02-09 | 2013-10-15 | Vascure Natural LLC | Cardiovascular support supplement and compositions and methods thereof |
| GB201002983D0 (en) | 2010-02-22 | 2010-04-07 | Tdeltas Ltd | Nutritinal composition |
| EP2694463B8 (de) | 2011-04-04 | 2019-10-09 | Berg LLC | Behandlung von tumoren im zentralnervensystem mit coenzym q10 |
| CN103874490A (zh) * | 2011-08-15 | 2014-06-18 | 工业研究与发展基金会有限公司 | 咔咯和他汀类药物的组合 |
| TWI489982B (zh) * | 2012-09-18 | 2015-07-01 | Univ China Medical | 苯醌類化合物應用於抑制動脈粥狀血管硬化之用途 |
| TWI504390B (zh) * | 2012-09-18 | 2015-10-21 | Univ China Medical | 苯醌類化合物應用於抑制黑色素瘤細胞之Wnt/β-catenin訊息途徑之用途 |
| AU2013337308B2 (en) | 2012-11-05 | 2018-06-21 | Tdeltas | Ketone bodies to protect tissues from damage by ionizing radiation |
| GB201304467D0 (en) | 2013-03-12 | 2013-04-24 | Tdeltas Ltd | Compound for use in protecting skin |
| CN105246870A (zh) | 2013-03-14 | 2016-01-13 | 伊希斯创新有限公司 | (r)-3-羟基丁酸(r)-3-羟基丁酯的制备方法 |
| SG11201508272YA (en) | 2013-04-08 | 2015-11-27 | Berg Llc | Treatment of cancer using coenzyme q10 combination therapies |
| WO2015003246A1 (en) * | 2013-07-09 | 2015-01-15 | Mcmaster University | Combination of a statin with an inflammasome inhibitor |
| JP6595478B2 (ja) | 2013-09-04 | 2019-10-23 | バーグ エルエルシー | コエンザイムq10の連続注入によるがんの治療方法 |
| WO2017087576A1 (en) | 2015-11-16 | 2017-05-26 | Berg Llc | Methods of treatment of temozolomide-resistant glioma using coenzyme q10 |
| WO2017106803A1 (en) | 2015-12-17 | 2017-06-22 | Bioelectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| IL270682B2 (en) | 2017-05-17 | 2025-09-01 | Berg Llc | Use of coenzyme q10 formulations for the treatment and prevention of bullous dermatitis of the skin |
| WO2018218287A1 (en) * | 2017-05-29 | 2018-12-06 | Woodlinda Pty Ltd | Treatment and/or prevention of neuropathic symptoms associated with diabetes mellitus type ii |
| US20220088040A1 (en) * | 2017-10-13 | 2022-03-24 | Exerkine Corporation | Use of System XC-Inhibitor for Treating Statin-Induced Myalgia |
| KR102060722B1 (ko) * | 2017-11-06 | 2020-02-11 | 연세대학교 산학협력단 | 스타틴에 의한 약물유해반응용 동물 모델 및 이의 제조방법 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2462312A1 (de) * | 1974-03-04 | 1976-10-14 | Nadrol Chemie Pharma Keizer Kg | Arzneimittel zur behandlung von migraene-erkrankungen |
| SU988814A1 (ru) * | 1979-11-20 | 1983-01-15 | Филиал Всесоюзного научно-исследовательского химико-фармацевтического института им.Серго Орджоникидзе | Соли оротовой кислоты и @ -аминокислот, предупреждающие развитие утомлени при физических нагрузках |
| DE3110560A1 (de) * | 1981-03-18 | 1982-10-14 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | "angiotropine der leukozyten und des entzuendungsgewebes: eine neue klasse natuerlicher chemotropischer mitogene fuer das richtungswachstum von blutgefaessen und zur neovaskularisierung von geweben" |
| US4911917A (en) * | 1988-06-28 | 1990-03-27 | Hauser-Kuhrts, Inc. | Cholesterol-lowering combination comopsitions of magnesium salt and niacin |
| US4929437A (en) * | 1989-02-02 | 1990-05-29 | Merck & Co., Inc. | Coenzyme Q10 with HMG-CoA reductase inhibitors |
| DE69001146T2 (de) * | 1989-01-18 | 1993-10-07 | Merck & Co Inc | Koenzym Q10 mit HMG-COA-Reduktase-Inhibitoren. |
| US5316765A (en) * | 1989-09-07 | 1994-05-31 | Karl Folkers Foundation For Biomedical And Clinical Research | Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies |
| WO1993016704A1 (en) * | 1992-02-24 | 1993-09-02 | East Carolina University | Method of inhibiting carcinogenesis by treatment with dehydroepiandrosterone and analogs thereof |
| BE1005939A6 (fr) * | 1992-05-14 | 1994-03-15 | Pirmez Thierry Dr | Utilisation des sels de l'acide orotique comme tranporteurs preferentiels d'oligo-elements. |
| DK0643775T3 (da) * | 1992-05-28 | 2004-09-06 | Ct For Molecular Biology And M | Quinonderivater til forbedring af cellebioenergi |
| AT405477B (de) * | 1996-04-03 | 1999-08-25 | Norbert Mag Fuchs | Kombinationspräparat |
| US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
| US6245800B1 (en) * | 1999-06-08 | 2001-06-12 | Sigma-Tau | Method of preventing or treating statin-induced toxic effects using L-carnitine or an alkanoyl L-carnitine |
| IT1317008B1 (it) * | 2000-04-04 | 2003-05-26 | Sigma Tau Healthscience Spa | Integratore alimentare energizzante sulla muscolatura scheletrica eprotettivo sull'apparato cardiovascolare. |
| US6420342B1 (en) * | 2000-05-08 | 2002-07-16 | N.V. Nutricia | Nutritional preparation comprising ribose and medical use thereof |
-
2000
- 2000-11-29 AU AUPR1773A patent/AUPR177300A0/en not_active Abandoned
-
2001
- 2001-11-29 JP JP2002545692A patent/JP4596734B2/ja not_active Expired - Fee Related
- 2001-11-29 NZ NZ526069A patent/NZ526069A/en not_active IP Right Cessation
- 2001-11-29 DE DE60130023T patent/DE60130023T2/de not_active Expired - Lifetime
- 2001-11-29 US US10/433,074 patent/US20040063661A1/en not_active Abandoned
- 2001-11-29 EP EP01998341A patent/EP1343488B1/de not_active Expired - Lifetime
- 2001-11-29 AT AT01998341T patent/ATE369845T1/de not_active IP Right Cessation
- 2001-11-29 AU AU2002223302A patent/AU2002223302B2/en not_active Ceased
- 2001-11-29 CA CA2429979A patent/CA2429979C/en not_active Expired - Fee Related
- 2001-11-29 WO PCT/AU2001/001545 patent/WO2002043721A1/en not_active Ceased
- 2001-11-29 ES ES01998341T patent/ES2292643T3/es not_active Expired - Lifetime
- 2001-11-29 AU AU2330202A patent/AU2330202A/xx active Pending
-
2010
- 2010-02-16 US US12/706,257 patent/US20100144665A1/en not_active Abandoned
- 2010-07-02 JP JP2010151665A patent/JP2010248230A/ja active Pending
- 2010-08-04 US US12/849,943 patent/US20100323981A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HK1059044A1 (en) | 2004-06-18 |
| JP2010248230A (ja) | 2010-11-04 |
| US20100144665A1 (en) | 2010-06-10 |
| NZ526069A (en) | 2006-11-30 |
| AU2330202A (en) | 2002-06-11 |
| US20040063661A1 (en) | 2004-04-01 |
| CA2429979C (en) | 2011-11-15 |
| AU2002223302B2 (en) | 2006-08-31 |
| EP1343488A4 (de) | 2005-05-04 |
| AUPR177300A0 (en) | 2000-12-21 |
| EP1343488B1 (de) | 2007-08-15 |
| JP4596734B2 (ja) | 2010-12-15 |
| EP1343488A1 (de) | 2003-09-17 |
| WO2002043721A1 (en) | 2002-06-06 |
| DE60130023D1 (de) | 2007-09-27 |
| CA2429979A1 (en) | 2002-06-06 |
| DE60130023T2 (de) | 2008-05-08 |
| JP2004531468A (ja) | 2004-10-14 |
| ES2292643T3 (es) | 2008-03-16 |
| US20100323981A1 (en) | 2010-12-23 |
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