ATE369873T1 - Metabolische intervention mit glp-1 oder seinen biologisch aktiven analogen zur verbesserung der funktion des ischämischen und wiederdurchbluteten gehirns - Google Patents
Metabolische intervention mit glp-1 oder seinen biologisch aktiven analogen zur verbesserung der funktion des ischämischen und wiederdurchbluteten gehirnsInfo
- Publication number
- ATE369873T1 ATE369873T1 AT00928616T AT00928616T ATE369873T1 AT E369873 T1 ATE369873 T1 AT E369873T1 AT 00928616 T AT00928616 T AT 00928616T AT 00928616 T AT00928616 T AT 00928616T AT E369873 T1 ATE369873 T1 AT E369873T1
- Authority
- AT
- Austria
- Prior art keywords
- glp
- reperfumed
- ischemic
- brain
- improve
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/303,016 US6429197B1 (en) | 1998-10-08 | 1999-04-30 | Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE369873T1 true ATE369873T1 (de) | 2007-09-15 |
Family
ID=23170209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00928616T ATE369873T1 (de) | 1999-04-30 | 2000-05-01 | Metabolische intervention mit glp-1 oder seinen biologisch aktiven analogen zur verbesserung der funktion des ischämischen und wiederdurchbluteten gehirns |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6429197B1 (de) |
| EP (1) | EP1187628B1 (de) |
| JP (1) | JP2002543145A (de) |
| CN (1) | CN1376072A (de) |
| AT (1) | ATE369873T1 (de) |
| AU (2) | AU774084B2 (de) |
| CA (1) | CA2368772C (de) |
| DE (1) | DE60035987T2 (de) |
| ES (1) | ES2290029T3 (de) |
| IL (1) | IL145829A0 (de) |
| MX (1) | MXPA01010937A (de) |
| NO (1) | NO20015298L (de) |
| NZ (1) | NZ514609A (de) |
| WO (1) | WO2000066142A2 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7138486B2 (en) * | 1986-05-05 | 2006-11-21 | The General Hospital Corporation | Insulinotropic hormone derivatives and uses thereof |
| US6849708B1 (en) * | 1986-05-05 | 2005-02-01 | The General Hospital Corporation | Insulinotropic hormone and uses thereof |
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| US6924264B1 (en) * | 1999-04-30 | 2005-08-02 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
| US20060160740A1 (en) * | 1999-10-21 | 2006-07-20 | Suad Efendic | Use of GLP-1 or analogs in treatment of stroke |
| EP1803730A1 (de) | 2000-04-12 | 2007-07-04 | Human Genome Sciences, Inc. | Albuminfusionsproteine |
| US6706689B2 (en) * | 2000-05-19 | 2004-03-16 | Amylin Pharmaceuticals, Inc. | Treatment of acute coronary syndrome with GLP-1 |
| EP1294757B1 (de) * | 2000-06-16 | 2006-11-22 | Eli Lilly And Company | Analoge des glucagon ähnlichen peptid-1 |
| DE60136958D1 (de) | 2000-12-01 | 2009-01-22 | Takeda Pharmaceutical | Verfahren zur herstellung einer zubereitung mit einer bioaktiven substanz |
| JP2002293799A (ja) * | 2001-03-29 | 2002-10-09 | Itoham Foods Inc | 新規ペプチド及びそれを含有する消化管運動抑制剤 |
| EP1411968B1 (de) * | 2001-07-31 | 2008-09-17 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Glp 1 exendin 4 peptidanaloga und deren verwendungen |
| EP1997829A1 (de) | 2001-12-21 | 2008-12-03 | Human Genome Sciences, Inc. | Albumin Fusionsproteine |
| CA2513213C (en) | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| WO2004071393A2 (en) * | 2003-02-13 | 2004-08-26 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with glucagon-like peptide 1 receptor (glp1r) |
| EP3572106A1 (de) | 2003-04-23 | 2019-11-27 | Valeritas, Inc. | Hydraulisch aktivierte pumpe für langzeitabgabe von medikamenten |
| US20080194483A1 (en) * | 2003-12-12 | 2008-08-14 | Brownlee Michael A | GLP-1 (9-36) methods and compositions |
| CA2550217A1 (en) * | 2003-12-12 | 2005-07-07 | Michael A. Brownlee | Glp-1 (9-36) methods and compositions |
| WO2006014425A1 (en) | 2004-07-02 | 2006-02-09 | Biovalve Technologies, Inc. | Methods and devices for delivering glp-1 and uses thereof |
| CN103239773B (zh) | 2006-03-30 | 2015-08-26 | 瓦莱里塔斯公司 | 多筒式流体递送器械 |
| US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
| WO2010013012A2 (en) * | 2008-08-01 | 2010-02-04 | Lund University Bioscience Ab | Novel polypeptides and uses thereof |
| US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
| CA2737461A1 (en) | 2008-09-19 | 2010-03-25 | Tandem Diabetes Care, Inc. | Solute concentration measurement device and related methods |
| US8926561B2 (en) | 2009-07-30 | 2015-01-06 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| CN101706297B (zh) * | 2009-08-10 | 2012-10-17 | 浙江鼎立实业有限公司 | 数显式微压和微流量综合检测台 |
| US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
| US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| EP2873422A4 (de) | 2012-07-10 | 2015-12-30 | Takeda Pharmaceutical | Pharmazeutische zubereitung zur injektion |
| CN103566354B (zh) * | 2012-07-25 | 2017-12-05 | 江苏豪森药业集团有限公司 | 含有glp‑1类似物的衍生物或其可药用盐的药物组合物 |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| LT2934568T (lt) | 2012-12-21 | 2018-02-12 | Sanofi | Dvigubi glp1/gip arba trigubi glp/gip/gliukagono agonistai |
| US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
| TW201609797A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/升糖素受體促效劑 |
| EP3080152A1 (de) | 2013-12-13 | 2016-10-19 | Sanofi | Nicht-acylierte exendin-4-peptidanaloga |
| WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
| EP3080150B1 (de) | 2013-12-13 | 2018-08-01 | Sanofi | Exendin-4-peptidanaloga als duale glp-1/gip-rezeptoragonisten |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
| CN118078956A (zh) * | 2016-05-06 | 2024-05-28 | 免疫新炉有限公司 | 用于受控和持续释放的elp融合蛋白 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4196196A (en) * | 1978-06-19 | 1980-04-01 | Tiholiz Ivan C | Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states |
| US4976959A (en) * | 1986-05-12 | 1990-12-11 | Burroughs Wellcome Co. | T-PA and SOD in limiting tissue damage |
| US6204259B1 (en) * | 1993-01-14 | 2001-03-20 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| US5424286A (en) * | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| US5373016A (en) | 1993-05-28 | 1994-12-13 | Zeneca, Inc. | Protection of isothiazolinone biocides from free radicals |
| US5574008A (en) | 1994-08-30 | 1996-11-12 | Eli Lilly And Company | Biologically active fragments of glucagon-like insulinotropic peptide |
| US5512549A (en) | 1994-10-18 | 1996-04-30 | Eli Lilly And Company | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
| US6277819B1 (en) | 1996-08-30 | 2001-08-21 | Eli Lilly And Company | Use of GLP-1 or analogs in treatment of myocardial infarction |
| DK1629849T4 (en) | 1997-01-07 | 2017-12-04 | Amylin Pharmaceuticals Llc | Pharmaceutical compositions comprising exedins and agonists thereof |
| US5846937A (en) | 1997-03-03 | 1998-12-08 | 1149336 Ontario Inc. | Method of using exendin and GLP-1 to affect the central nervous system |
| WO1998043658A1 (en) * | 1997-03-31 | 1998-10-08 | Eli Lilly And Company | Glucagon-like peptide-1 analogs |
| MY155270A (en) * | 1998-09-24 | 2015-09-30 | Lilly Co Eli | Use of glp-1 or analogs in treatment of stroke |
| US6284725B1 (en) | 1998-10-08 | 2001-09-04 | Bionebraska, Inc. | Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue |
| NZ519752A (en) | 2000-10-20 | 2005-04-29 | Amylin Pharmaceuticals Inc | Treatment of hibernating myocardium and diabetic cardiomyopathy with a GLP-1 peptide |
-
1999
- 1999-04-30 US US09/303,016 patent/US6429197B1/en not_active Ceased
-
2000
- 2000-05-01 IL IL14582900A patent/IL145829A0/xx not_active IP Right Cessation
- 2000-05-01 CN CN00806935A patent/CN1376072A/zh active Pending
- 2000-05-01 AU AU46825/00A patent/AU774084B2/en not_active Ceased
- 2000-05-01 ES ES00928616T patent/ES2290029T3/es not_active Expired - Lifetime
- 2000-05-01 JP JP2000615026A patent/JP2002543145A/ja active Pending
- 2000-05-01 AT AT00928616T patent/ATE369873T1/de not_active IP Right Cessation
- 2000-05-01 WO PCT/US2000/011652 patent/WO2000066142A2/en not_active Ceased
- 2000-05-01 NZ NZ514609A patent/NZ514609A/xx not_active IP Right Cessation
- 2000-05-01 MX MXPA01010937A patent/MXPA01010937A/es active IP Right Grant
- 2000-05-01 DE DE60035987T patent/DE60035987T2/de not_active Expired - Lifetime
- 2000-05-01 CA CA2368772A patent/CA2368772C/en not_active Expired - Fee Related
- 2000-05-01 EP EP00928616A patent/EP1187628B1/de not_active Expired - Lifetime
-
2001
- 2001-10-29 NO NO20015298A patent/NO20015298L/no not_active Application Discontinuation
-
2004
- 2004-08-06 US US10/913,309 patent/USRE41288E1/en not_active Expired - Lifetime
- 2004-09-15 AU AU2004212547A patent/AU2004212547B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01010937A (es) | 2002-05-06 |
| EP1187628A2 (de) | 2002-03-20 |
| USRE41288E1 (en) | 2010-04-27 |
| WO2000066142A2 (en) | 2000-11-09 |
| ES2290029T3 (es) | 2008-02-16 |
| NO20015298L (no) | 2001-12-28 |
| DE60035987D1 (de) | 2007-09-27 |
| JP2002543145A (ja) | 2002-12-17 |
| EP1187628B1 (de) | 2007-08-15 |
| CN1376072A (zh) | 2002-10-23 |
| US6429197B1 (en) | 2002-08-06 |
| WO2000066142A3 (en) | 2002-01-24 |
| AU774084B2 (en) | 2004-06-17 |
| CA2368772C (en) | 2011-11-15 |
| DE60035987T2 (de) | 2008-05-08 |
| AU2004212547A1 (en) | 2004-10-14 |
| AU2004212547B2 (en) | 2008-03-20 |
| CA2368772A1 (en) | 2000-11-09 |
| AU4682500A (en) | 2000-11-17 |
| NO20015298D0 (no) | 2001-10-29 |
| IL145829A0 (en) | 2002-07-25 |
| NZ514609A (en) | 2004-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE369873T1 (de) | Metabolische intervention mit glp-1 oder seinen biologisch aktiven analogen zur verbesserung der funktion des ischämischen und wiederdurchbluteten gehirns | |
| MXPA05006994A (es) | Composiciones y metodos para la prevencion y el control de hipoglucemia inducida por insulina. | |
| EA200701956A1 (ru) | Лекарственные формы октреотида с контролируемым высвобождением | |
| EA200501422A1 (ru) | Длительнодействующая инъецируемая композиция инсулина и способы её изготовления и применения | |
| MY158627A (en) | Halogen-stabilized insulin | |
| ATE283701T1 (de) | Metabolische intervention mit glp-1 zur verbesserung der funktion von ischämischem und wiederdurchblutetem gewebe | |
| RU2011119988A (ru) | Композиции инсулинов длительного действия | |
| PE20011363A1 (es) | Analogos del peptido-1 semejante a glucagon | |
| IL208184A0 (en) | Glp-1, and methods for treating diabetes | |
| PH12015501009B1 (en) | A composition for treating diabetes or diabesity comprising oxyntomodulin analog | |
| MX366314B (es) | Uso de derivados de insulina por inyecciones con intervalos variables. | |
| ES2099245T3 (es) | Tratamiento de la osteoporosis usando factor de liberacion de hormona de crecimiento (grf) en combinacion con hormona paratiroidea (pth). | |
| EA200200324A1 (ru) | Способы применения селективных ингибиторов обратного захвата серотонина быстрого запуска для лечения половой дисфункции | |
| AU2002331226A1 (en) | Methods for improving islet signaling in diabetes mellitus and for its prevention | |
| EP1153607A3 (de) | Wachstumshormon zur Behandlung von Gelenkentzündung | |
| RU2003113987A (ru) | Способ лечения и профилактики заболеваний воздействием на биологически активные точки и зоны | |
| MX2025011528A (es) | Tirzepatida para usar en el tratamiento de dt2 | |
| ECSP982534A (es) | Nuevo metodo de tratamiento | |
| PL372345A1 (en) | Treatment of type i diabetes mellitus using growth hormone antagonist | |
| ECSP982542A (es) | Nuevo metodo de tratamiento iii | |
| James | Successful treatment of" buffalo hump" with growth hormone | |
| AR077460A1 (es) | Uso de la combinacion de teriflunomida e interferon beta para el tratamiento de la esclerosis multiple | |
| UA116600U (uk) | Спосіб лікування гострого ішемічного інсульту | |
| RU2009145054A (ru) | Оксинтомодулин человека, его применение, лекарственный препарат на его основе и способ применения препарата для лечения и профилактики гипергликемии | |
| AU8716001A (en) | Treatment of hepatitis c with thymosin and pegylated interferon |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |