ATE370411T1 - Verfahren zum screening - Google Patents

Verfahren zum screening

Info

Publication number
ATE370411T1
ATE370411T1 AT01904318T AT01904318T ATE370411T1 AT E370411 T1 ATE370411 T1 AT E370411T1 AT 01904318 T AT01904318 T AT 01904318T AT 01904318 T AT01904318 T AT 01904318T AT E370411 T1 ATE370411 T1 AT E370411T1
Authority
AT
Austria
Prior art keywords
salt
tgr
screening procedure
neuromedin
hypertension
Prior art date
Application number
AT01904318T
Other languages
English (en)
Inventor
Shuji Hinuma
Yasushi Shintani
Masaki Hosoya
Ryo Fujii
Takeo Moriya
Hideki Matsui
Shoichi Okubo
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE370411T1 publication Critical patent/ATE370411T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9453—Cardioregulators, e.g. antihypotensives, antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00689—Automatic using computers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00695—Synthesis control routines, e.g. using computer programs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Holo Graphy (AREA)
AT01904318T 2000-02-04 2001-02-02 Verfahren zum screening ATE370411T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000032773 2000-02-04
JP2000052252 2000-02-24
JP2000097896 2000-03-30
JP2000187536 2000-06-19

Publications (1)

Publication Number Publication Date
ATE370411T1 true ATE370411T1 (de) 2007-09-15

Family

ID=27481019

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01904318T ATE370411T1 (de) 2000-02-04 2001-02-02 Verfahren zum screening

Country Status (10)

Country Link
US (1) US7138249B2 (de)
EP (1) EP1255109B1 (de)
KR (1) KR20020086491A (de)
CN (1) CN1397019A (de)
AT (1) ATE370411T1 (de)
AU (1) AU3222701A (de)
CA (1) CA2399052A1 (de)
DE (1) DE60129933T2 (de)
IL (1) IL150824A0 (de)
WO (1) WO2001057524A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6998255B1 (en) * 1999-09-24 2006-02-14 Solvay Pharmaceuticals B.V. Human G-protein coupled receptor
US6461836B1 (en) 1999-11-05 2002-10-08 Smithkline Beecham Corporation Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof
WO2001081418A1 (en) 2000-04-27 2001-11-01 Merck & Co., Inc. New neuromedin u receptor nmur2 and nucleotides encoding it
GB0100782D0 (en) * 2001-01-11 2001-02-21 Glaxo Group Ltd Assay
EP1365246A1 (de) * 2002-05-23 2003-11-26 Bayer Ag Diagnose und Therapie von mit dem Neuromedin U2 Rezeptor assoziierten Erkrankungen
US7943580B2 (en) 2004-12-24 2011-05-17 National Cerebral And Cardiovascular Center Polypeptide and the use thereof
WO2008029601A1 (fr) * 2006-08-16 2008-03-13 Forerunner Pharma Research Co., Ltd. Agent thérapeutique cancéreux comprenant un ligand pour la molécule (fm4) du récepteur 2 de neuromédine u en tant qu'ingrédient actif
US7767826B2 (en) * 2007-10-05 2010-08-03 Pharmatech International, Inc. Process for the synthesis of L-(+)-ergothioneine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801455D0 (sv) * 1998-04-24 1998-04-24 Astra Pharma Inc New receptor
WO2000002919A1 (en) 1998-07-13 2000-01-20 Merck & Co., Inc. Growth hormone secretagogue related receptors and nucleic acids
NZ510712A (en) 1998-10-13 2004-11-26 Arena Pharm Inc Non-endogenous, constitutively activated human G protein-coupled receptors
ATE301673T1 (de) 1998-11-20 2005-08-15 Arena Pharm Inc Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
US20030017528A1 (en) * 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
EP1237001A4 (de) 1999-11-29 2005-03-23 Takeda Pharmaceutical Screeningverfahren
US7029857B1 (en) 1999-12-17 2006-04-18 H. Lundbeck A/S Processes for obtaining compounds employing SNORF72 receptors
WO2001081418A1 (en) 2000-04-27 2001-11-01 Merck & Co., Inc. New neuromedin u receptor nmur2 and nucleotides encoding it

Also Published As

Publication number Publication date
US7138249B2 (en) 2006-11-21
US20040152136A1 (en) 2004-08-05
IL150824A0 (en) 2003-02-12
EP1255109B1 (de) 2007-08-15
EP1255109A4 (de) 2005-03-23
DE60129933D1 (de) 2007-09-27
EP1255109A1 (de) 2002-11-06
WO2001057524A1 (fr) 2001-08-09
AU3222701A (en) 2001-08-14
KR20020086491A (ko) 2002-11-18
CA2399052A1 (en) 2001-08-09
DE60129933T2 (de) 2008-02-14
CN1397019A (zh) 2003-02-12

Similar Documents

Publication Publication Date Title
ATA8612001A (de) Verfahren zum testen von software
DE60326760D1 (de) Verfahren zum verbinden
DE60237458D1 (de) Verfahren zum einstecken von seitenteilen mit seitenteilfalz-lokalisationskontrolle
DE60013420D1 (de) Verfahren zum ringförmigen abdichten
DE60122131D1 (de) Verfahren zum verkleben eines fügeteils
DE60138969D1 (de) Werkzeug zum einfangen freier thromben
DE60203210D1 (de) Automatisches System zum Reparieren von Artikeln
DE50104569D1 (de) Verfahren zum behandeln von tabak
DE60132243D1 (de) Verfahren zum indizieren von entitäten
DE60222206D1 (de) Verfahren zum Schneiden von elastomerischen Materialien
DE50211265D1 (de) Verfahren zum Herstellen von Zigarettenpackungen
DE60136355D1 (de) Verfahren zum entwickeln von werkzeugen
DE60034527D1 (de) Verfahren und Vorrichtung zum Ausrichten von Gegenständen
DE60044618D1 (de) Verfahren zum verbinden von strickwaren
DE60206863D1 (de) Verfahren zum hydraulischen Transfer
DE60129933D1 (de) Verfahren zum screening
DE602004022156D1 (de) Verfahren zum verbinden von strickwaren
EP1305625A4 (de) Verfahren zum immunnachweis von epitopen
DE60113684D1 (de) Verfahren zum dispergieren von polyacrylamiden
DE50203911D1 (de) Verfahren zum aktivieren von sicherheitseinrichtungen
DE60130929D1 (de) Giessverfahren zum herstellen von zementgegenständen
DE60208973D1 (de) Verfahren zum Transportieren von sehr grossen Reifen
DE50105330D1 (de) Verfahren zum herstellen von flachbandkabeln
DE60118595D1 (de) Verfahren zum hydrieren von gipsplatten, einrichtung dafür
DE50106697D1 (de) Verfahren zum auffinden von objekten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties