ATE370414T1 - Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs - Google Patents

Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs

Info

Publication number
ATE370414T1
ATE370414T1 AT03813582T AT03813582T ATE370414T1 AT E370414 T1 ATE370414 T1 AT E370414T1 AT 03813582 T AT03813582 T AT 03813582T AT 03813582 T AT03813582 T AT 03813582T AT E370414 T1 ATE370414 T1 AT E370414T1
Authority
AT
Austria
Prior art keywords
colorectal cancer
methyltransferase
nicotinamide
diagnosis
diagnosing colorectal
Prior art date
Application number
AT03813582T
Other languages
English (en)
Inventor
Peter Berndt
Marie-Luise Hagmann
Hanno Langen
Stefan Palme
Markus Roessler
Wolfgang Rollinger
Michael Tacke
Werner Zolg
Johann Karl
Theresa Kott
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE370414T1 publication Critical patent/ATE370414T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03813582T 2002-12-20 2003-12-19 Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs ATE370414T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02028715 2002-12-20

Publications (1)

Publication Number Publication Date
ATE370414T1 true ATE370414T1 (de) 2007-09-15

Family

ID=32668733

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03813582T ATE370414T1 (de) 2002-12-20 2003-12-19 Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs

Country Status (13)

Country Link
US (1) US7205118B2 (de)
EP (1) EP1579220B1 (de)
JP (1) JP4248496B2 (de)
KR (1) KR100711046B1 (de)
CN (1) CN100437115C (de)
AT (1) ATE370414T1 (de)
AU (1) AU2003296684A1 (de)
BR (1) BR0317394A (de)
CA (1) CA2510377C (de)
DE (1) DE60315715T2 (de)
ES (1) ES2291750T3 (de)
MX (1) MXPA05006382A (de)
WO (1) WO2004057336A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE370414T1 (de) 2002-12-20 2007-09-15 Hoffmann La Roche Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs
WO2005124353A1 (en) * 2004-06-18 2005-12-29 Roch Diagnostics Gmbh Use of inorganic pyrophosphatase as a marker for colorectal cancer
ATE426168T1 (de) * 2004-12-23 2009-04-15 Hoffmann La Roche Verwendung von asc als marker fur kolorektalkarzinome
WO2006066916A1 (en) * 2004-12-23 2006-06-29 Roche Diagnostics Gmbh Use of microsomal dipeptidase as a marker for colorectal cancer
CA2585788C (en) 2004-12-23 2013-03-05 F. Hoffmann-La Roche Ag Use of cyfra 21-1 as a marker for colorectal cancer
EP1917530B1 (de) 2005-08-19 2011-02-23 Indivumed GmbH Verwendung eines endoplasmin-fragments und von derivaten davon als biomarker für kolorektaladenom und/oder -karzinom; nachweisverfahren und testsystem
CN101346628A (zh) * 2005-12-22 2009-01-14 霍夫曼-拉罗奇有限公司 包含骨桥蛋白和癌胚抗原的标记物组合在结肠直肠癌的评估中的用途
JP4981133B2 (ja) * 2006-08-01 2012-07-18 エフ．ホフマン−ラ ロシュ アーゲー 肺癌用マーカーとしてのｎｎｍｔの使用
US20110104177A1 (en) * 2006-12-28 2011-05-05 The Johns Hopkins University Histone deacetylase inhibitors, combination therapies and methods of use
KR100883530B1 (ko) 2007-07-30 2009-02-13 한국과학기술연구원 대장암 진단용 단백질 마커 아데노실호모시스테이나제 및이에 대한 항체를 포함하는 대장암 진단키트
KR101458483B1 (ko) 2007-08-06 2014-11-10 제노마인(주) 신장암 진단 조성물 및 키트
ES2490613T3 (es) 2008-12-22 2014-09-04 F. Hoffmann-La Roche Ag ARMET como marcador de cáncer
US10815517B2 (en) 2009-04-28 2020-10-27 Roche Diagnostics Operations, Inc. Use of DPPIV/seprase as a marker for cancer
JP5731488B2 (ja) 2009-05-29 2015-06-10 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 癌のマーカーとしてのセセルニン‐１
EP2454596B1 (de) 2009-07-16 2014-06-11 Roche Diagnostics GmbH Flap-endonuklease-1 als marker für krebs
CN102375049A (zh) * 2010-08-04 2012-03-14 索尼公司 生物信息获取方法和烟酰胺代谢物测量方法
CN103415770B (zh) * 2011-03-11 2015-09-02 霍夫曼-拉罗奇有限公司 Nnmt作为慢性阻塞性肺病(copd)的标志物
CA2948548C (en) 2014-05-13 2022-06-28 Vastcon Methionine aminopeptidase overexpression in the peripheral blood and peripheral blood mononuclear cells is a marker for colorectal cancer screening, diagnosis and prognosis
CN104894073B (zh) * 2015-02-16 2018-03-27 浙江大学 杂交瘤细胞株Zj/2D8及其检测尼克酰胺‑N‑甲基化酶抗原的应用
CN110308281B (zh) * 2019-06-06 2022-08-23 北京蛋白质组研究中心 一种泛素链固相检测方法和应用
CN116726012B (zh) * 2023-03-16 2026-02-27 华中科技大学同济医学院附属协和医院 Nnmt在炎症性肠病诊断和治疗中的用途

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Publication number Priority date Publication date Assignee Title
US5547928A (en) 1993-12-17 1996-08-20 Matritech, Inc. Methods and compositions for the detection of colon cancers
WO1996039419A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Colon specific genes and proteins
US5939265A (en) * 1996-11-05 1999-08-17 Abbott Laboratories Reagents and methods useful for detecting diseases of the lung
EP1108021A2 (de) 1998-08-31 2001-06-20 Bayer Corporation Humane gene differentiell exprimiert in kolorektalkrebs
US6936424B1 (en) 1999-11-16 2005-08-30 Matritech, Inc. Materials and methods for detection and treatment of breast cancer
AU2001252945A1 (en) 2000-03-24 2001-10-08 Corixa Corporation Compositions and methods for therapy and diagnosis of colon cancer
WO2001096390A2 (en) 2000-06-09 2001-12-20 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
US20020177552A1 (en) 2000-06-09 2002-11-28 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
AU2001266790A1 (en) 2000-06-09 2001-12-24 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
AU2001280982A1 (en) 2000-08-03 2002-02-18 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
WO2002012280A2 (en) 2000-08-03 2002-02-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
JP2002070501A (ja) 2000-09-04 2002-03-08 Honda Motor Co Ltd 回転流体機械
AU2002306952A1 (en) 2001-03-28 2002-10-15 Matritech, Inc. Detection and treatment of colorectal cancer
AU2002257254A1 (en) * 2001-05-07 2002-11-18 Genaissance Pharmaceuticals, Inc. Haplotypes of the nnmt gene
ATE370414T1 (de) 2002-12-20 2007-09-15 Hoffmann La Roche Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs

Also Published As

Publication number Publication date
DE60315715T2 (de) 2008-06-05
HK1088947A1 (zh) 2006-11-17
US7205118B2 (en) 2007-04-17
KR20050114604A (ko) 2005-12-06
EP1579220A2 (de) 2005-09-28
CN100437115C (zh) 2008-11-26
CN1742204A (zh) 2006-03-01
CA2510377A1 (en) 2004-07-08
MXPA05006382A (es) 2005-10-24
WO2004057336A3 (en) 2005-01-20
JP4248496B2 (ja) 2009-04-02
US20060003368A1 (en) 2006-01-05
ES2291750T3 (es) 2008-03-01
WO2004057336A2 (en) 2004-07-08
DE60315715D1 (de) 2007-09-27
EP1579220B1 (de) 2007-08-15
AU2003296684A1 (en) 2004-07-14
JP2006510889A (ja) 2006-03-30
BR0317394A (pt) 2005-11-16
KR100711046B1 (ko) 2007-04-24
CA2510377C (en) 2009-11-17

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