ATE371735T1 - Hematopoietischer zytokin rezeptor - Google Patents
Hematopoietischer zytokin rezeptorInfo
- Publication number
- ATE371735T1 ATE371735T1 AT97924775T AT97924775T ATE371735T1 AT E371735 T1 ATE371735 T1 AT E371735T1 AT 97924775 T AT97924775 T AT 97924775T AT 97924775 T AT97924775 T AT 97924775T AT E371735 T1 ATE371735 T1 AT E371735T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- cells
- cytokine receptor
- ligand
- vitro
- Prior art date
Links
- 102000003675 cytokine receptors Human genes 0.000 title 1
- 108010057085 cytokine receptors Proteins 0.000 title 1
- 230000003394 haemopoietic effect Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 239000003446 ligand Substances 0.000 abstract 3
- 238000000338 in vitro Methods 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000005962 receptors Human genes 0.000 abstract 2
- 108010001857 Cell Surface Receptors Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
- 108020001756 ligand binding domains Proteins 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 210000003563 lymphoid tissue Anatomy 0.000 abstract 1
- 102000006240 membrane receptors Human genes 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000000066 myeloid cell Anatomy 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/653,740 US5792850A (en) | 1996-05-23 | 1996-05-23 | Hematopoietic cytokine receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE371735T1 true ATE371735T1 (de) | 2007-09-15 |
Family
ID=24622131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97924775T ATE371735T1 (de) | 1996-05-23 | 1997-05-19 | Hematopoietischer zytokin rezeptor |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US5792850A (de) |
| EP (2) | EP1555318A3 (de) |
| JP (1) | JP2000512492A (de) |
| AT (1) | ATE371735T1 (de) |
| AU (1) | AU3009397A (de) |
| DE (1) | DE69738066T2 (de) |
| WO (1) | WO1997044455A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6153424A (en) * | 1995-11-09 | 2000-11-28 | Zymogenetics, Inc. | Protease-deficient strains of Pichia methanolica |
| US8212004B2 (en) | 1999-03-02 | 2012-07-03 | Human Genome Sciences, Inc. | Neutrokine-alpha fusion proteins |
| US6812327B1 (en) | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
| CA2315977A1 (en) * | 1997-12-24 | 1999-07-08 | Ludwig Institute For Cancer Research | Expression vectors and cell lines expressing vascular endothelial growth factor d, and method of treating melanomas |
| WO1999040195A1 (en) * | 1998-02-06 | 1999-08-12 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
| US20020098541A1 (en) * | 1998-10-20 | 2002-07-25 | Jian Ni | TNFR related gene 12 |
| US6986990B1 (en) * | 1999-04-27 | 2006-01-17 | Genox Research, Inc. | Pollen allergy-related gene 513 |
| US20030153050A1 (en) * | 1999-06-28 | 2003-08-14 | Conklin Darrell C. | Helical polypeptide zalpha29 |
| AU7078200A (en) | 1999-08-27 | 2001-03-26 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Polypeptides, comprising il-6 ligand-binding receptor domains and related nucleic acids, antibodies, compositions, and methods of use |
| KR100874280B1 (ko) * | 1999-10-20 | 2008-12-18 | 제넨테크, 인크. | T 헬퍼 세포 매개 질환의 치료를 위한 t 세포 분화의조절 |
| US6346247B1 (en) | 1999-10-28 | 2002-02-12 | Promega Corporation | Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies |
| US7879328B2 (en) | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
| PT2281843T (pt) | 2000-06-16 | 2017-01-02 | Human Genome Sciences Inc | Anticorpos que se ligam imunoespecificamente a blys |
| US7393532B1 (en) * | 2000-10-18 | 2008-07-01 | Genentech, Inc. | Modulation of T cell differentiation for the treatment of T helper cell mediated diseases |
| EP2840089A1 (de) | 2002-01-18 | 2015-02-25 | ZymoGenetics, Inc. | Zytokinrezeptor Zyctor17-Multimere |
| US9738700B2 (en) | 2002-01-18 | 2017-08-22 | Zymogenetics Inc. | ZCYTOR17 heterodimeric cytokine receptor |
| DK1961811T3 (da) | 2002-01-18 | 2010-11-08 | Zymogenetics Inc | Cytokinligand til behandling af asthma og luftvejs-hyper-responsivitet |
| WO2005018552A2 (en) * | 2003-08-12 | 2005-03-03 | University Of Utah Research Foundation | Heparin binding proteins: sensors for heparin detection |
| ATE517914T1 (de) | 2004-03-08 | 2011-08-15 | Zymogenetics Inc | Dimere fusionsproteine und materialien und verfahren zu deren herstellung |
| US20060177436A1 (en) * | 2004-12-16 | 2006-08-10 | Genentech, Inc. | Methods for Treating Autoimmune Disorders |
| JP2008528039A (ja) * | 2005-01-28 | 2008-07-31 | ザイモジェネティクス,インコーポレイティド | Il−31の均質調製物 |
| WO2006088955A2 (en) * | 2005-02-14 | 2006-08-24 | Zymogenetics, Inc. | Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells |
| US8101183B2 (en) | 2005-05-06 | 2012-01-24 | Zymogentics, Inc. | Variable region sequences of IL-31 monoclonal antibodies |
| KR101443050B1 (ko) * | 2005-05-06 | 2014-09-22 | 지모제넥틱스, 인코포레이티드 | Il-31 단클론성 항체 및 사용법 |
| US20130216542A1 (en) | 2005-05-06 | 2013-08-22 | Zymogenetics, Inc. | Variable region sequences of il-31 monoclonal antibodies and methods of use |
| US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
| EP2749571A3 (de) | 2006-01-10 | 2014-08-13 | ZymoGenetics, Inc. | Verfahren zur Behandlung von Schmerzen und Entzündungen in Nervengewebe mithilfe von IL-31RA- und OSMRb-Antagonisten |
| WO2007123765A2 (en) | 2006-03-31 | 2007-11-01 | Human Genome Sciences Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
| WO2008025032A1 (en) * | 2006-08-25 | 2008-02-28 | Zymogenetics, Inc. | Soluble il-27 receptor |
| JP2010515755A (ja) | 2007-01-10 | 2010-05-13 | ザイモジェネティクス, インコーポレイテッド | 気道過敏および喘息を処置するためのil−31の使用法 |
| ME03057B (de) | 2007-12-07 | 2019-01-20 | Zymogenetics Inc | Für IL-31 spezifische humanisierte Antikörpermoleküle |
| US8309688B2 (en) * | 2008-12-30 | 2012-11-13 | Centocor Ortho Biotech Inc. | Monkey homolog of human oncostatin M and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68926888T2 (de) * | 1988-01-22 | 1997-01-09 | Zymogenetics Inc | Verfahren zur Herstellung von sekretierten Rezeptoranalogen |
| CA2097291A1 (en) * | 1990-12-13 | 1992-06-14 | David P. Gearing | Leukemia inhibitory factor receptors |
| CA2164623A1 (en) * | 1993-06-07 | 1994-12-22 | Robert Enrico Pacifici | Hybrid receptor molecules |
| NZ271230A (en) * | 1994-02-14 | 1998-03-25 | Zymogenetics Inc | Hematopoietic proteins, production and use |
-
1996
- 1996-05-23 US US08/653,740 patent/US5792850A/en not_active Expired - Lifetime
-
1997
- 1997-05-19 DE DE69738066T patent/DE69738066T2/de not_active Expired - Fee Related
- 1997-05-19 JP JP09542641A patent/JP2000512492A/ja active Pending
- 1997-05-19 WO PCT/US1997/008502 patent/WO1997044455A1/en not_active Ceased
- 1997-05-19 EP EP04030182A patent/EP1555318A3/de not_active Withdrawn
- 1997-05-19 EP EP97924775A patent/EP0910635B1/de not_active Expired - Lifetime
- 1997-05-19 AT AT97924775T patent/ATE371735T1/de not_active IP Right Cessation
- 1997-05-19 AU AU30093/97A patent/AU3009397A/en not_active Abandoned
-
1998
- 1998-05-06 US US09/073,594 patent/US5925735A/en not_active Expired - Fee Related
-
1999
- 1999-03-24 US US09/275,925 patent/US6080406A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5925735A (en) | 1999-07-20 |
| AU3009397A (en) | 1997-12-09 |
| US6080406A (en) | 2000-06-27 |
| EP0910635B1 (de) | 2007-08-29 |
| EP1555318A2 (de) | 2005-07-20 |
| EP0910635A1 (de) | 1999-04-28 |
| DE69738066D1 (de) | 2007-10-11 |
| US5792850A (en) | 1998-08-11 |
| EP1555318A3 (de) | 2008-10-08 |
| JP2000512492A (ja) | 2000-09-26 |
| DE69738066T2 (de) | 2008-05-21 |
| WO1997044455A1 (en) | 1997-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |