ATE37185T1 - Kontrazeptive zusammensetzungen auf basis von levo-norgestrel-estern. - Google Patents

Kontrazeptive zusammensetzungen auf basis von levo-norgestrel-estern.

Info

Publication number: ATE37185T1
Authority: AT; Austria
Prior art keywords: norgestrel; levo; esters; oxime; compositions based
Prior art date: 1983-05-19

Application number

AT84300611T

Other languages

English (en)

Inventor

Sidney Department Of Ch Archer

Egon Swedish Medica Diczfalusy

Sjukhuset

Josef Department Of Chem Fried

Ellis Avenue South

Guiseppe Benagiano

Pierre Crabbe

Carl Djerassi

Original Assignee

World Health Org

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-05-19

Filing date

1984-01-31

Publication date

1988-09-15

1984-01-31 Application filed by World Health Org filed Critical World Health Org

1988-09-15 Application granted granted Critical

1988-09-15 Publication of ATE37185T1 publication Critical patent/ATE37185T1/de

Links

WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical class O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 title abstract 4
239000003433 contraceptive agent Substances 0.000 title abstract 2
230000002254 contraceptive effect Effects 0.000 title 1
239000000203 mixture Substances 0.000 title 1
150000002148 esters Chemical class 0.000 abstract 4
229960004400 levonorgestrel Drugs 0.000 abstract 3
TZZXNSUFTUXHRE-AYEDEZQKSA-N O([C@]1(CC[C@H]2[C@H]3[C@@H]([C@H]4CCC(=O)C=C4CC3)CC[C@@]21CC)C#C)C(=O)C1CC1 Chemical compound O([C@]1(CC[C@H]2[C@H]3[C@@H]([C@H]4CCC(=O)C=C4CC3)CC[C@@]21CC)C#C)C(=O)C1CC1 TZZXNSUFTUXHRE-AYEDEZQKSA-N 0.000 abstract 1
GPKLGCALNRZIDS-AYEDEZQKSA-N [(8r,9s,10r,13s,14s,17r)-13-ethyl-17-ethynyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] butanoate Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@](C#C)(OC(=O)CCC)[C@@]1(CC)CC2 GPKLGCALNRZIDS-AYEDEZQKSA-N 0.000 abstract 1
WWGTWFPUIPEHNX-UKNJCJGYSA-N [(8r,9s,10r,13s,14s,17r)-13-ethyl-17-ethynyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] cyclobutanecarboxylate Chemical compound O([C@]1(CC[C@H]2[C@H]3[C@@H]([C@H]4CCC(=O)C=C4CC3)CC[C@@]21CC)C#C)C(=O)C1CCC1 WWGTWFPUIPEHNX-UKNJCJGYSA-N 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
229940124558 contraceptive agent Drugs 0.000 abstract 1
230000001186 cumulative effect Effects 0.000 abstract 1
NZNMSOFKMUBTKW-UHFFFAOYSA-N cyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1 NZNMSOFKMUBTKW-UHFFFAOYSA-N 0.000 abstract 1
JBDSSBMEKXHSJF-UHFFFAOYSA-N cyclopentanecarboxylic acid Chemical compound OC(=O)C1CCCC1 JBDSSBMEKXHSJF-UHFFFAOYSA-N 0.000 abstract 1
230000007774 longterm Effects 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Orthopedics, Nursing, And Contraception (AREA)
Medicinal Preparation (AREA)

AT84300611T 1983-05-19 1984-01-31 Kontrazeptive zusammensetzungen auf basis von levo-norgestrel-estern. ATE37185T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB838313921A GB8313921D0 (en)	1983-05-19	1983-05-19	Contraceptive compositions
EP84300611A EP0129947B1 (de)	1983-05-19	1984-01-31	Kontrazeptive Zusammensetzungen auf Basis von Levo-Norgestrel-Estern

Publications (1)

Publication Number	Publication Date
ATE37185T1 true ATE37185T1 (de)	1988-09-15

Family

ID=10543055

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT84300611T ATE37185T1 (de)	1983-05-19	1984-01-31	Kontrazeptive zusammensetzungen auf basis von levo-norgestrel-estern.

Country Status (4)

Country	Link
EP (1)	EP0129947B1 (de)
AT (1)	ATE37185T1 (de)
DE (1)	DE3474024D1 (de)
GB (1)	GB8313921D0 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3511588A1 (de) *	1985-03-27	1986-10-02	Schering AG, Berlin und Bergkamen, 1000 Berlin	Waessrige kristallsuspension von steroidglykoestern
DE4232521A1 (de) *	1992-09-22	1994-03-24	Schering Ag	Gestagen wirksame 4,5;11,12-Estradiene, Verfahren zu ihrer Herstellung, diese Estradiene enthaltende Arzneimittel sowie deren Verwendung zur Herstellung von Arzneimitteln
AU4957999A (en) *	1998-07-17	2000-02-07	Pharmacia & Upjohn Company	Subcutaneous medroxyprogesterone acetate for contraception
TW200403065A (en) *	2002-05-30	2004-03-01	Akzo Nobel Nv	New etonogestrel esters
EP2399566A1 (de) *	2010-06-28	2011-12-28	Laboratoire HRA Pharma	Verfahren zur Empfängnisverhütung einmal im Monat
JP2019506443A (ja) *	2016-02-24	2019-03-07	イースタンバージニアメディカルスクール	改良された持効性注射用デポ型ブタン酸レボノルゲストレル懸濁製剤
WO2019078983A1 (en) *	2017-10-19	2019-04-25	Evestra, Inc.	CONTRACEPTIVES OF PROGESTINE PRODRANT WITH EXTENDED ACTION
US11186585B2 (en) *	2018-08-17	2021-11-30	Kappa-Pharma LLC	Compositions and methods of enhancing opioid receptor engagement by opioid hexadienoates and optionally substituted hexadienoates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4027019A (en) *	1975-07-24	1977-05-31	Ortho Pharmaceutical Corporation	3-Oximes of D-17α-ethynyl-19-nortestosterone esters and method

1983
- 1983-05-19 GB GB838313921A patent/GB8313921D0/en active Pending
1984
- 1984-01-31 EP EP84300611A patent/EP0129947B1/de not_active Expired
- 1984-01-31 DE DE8484300611T patent/DE3474024D1/de not_active Expired
- 1984-01-31 AT AT84300611T patent/ATE37185T1/de active

Also Published As

Publication number	Publication date
EP0129947A3 (en)	1985-05-22
EP0129947A2 (de)	1985-01-02
DE3474024D1 (en)	1988-10-20
EP0129947B1 (de)	1988-09-14
GB8313921D0 (en)	1983-06-22

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