ATE372126T1 - Spüllösung und verfahren zur schmerzlinderung und entzündungshemmung - Google Patents

Spüllösung und verfahren zur schmerzlinderung und entzündungshemmung

Info

Publication number: ATE372126T1
Authority: AT; Austria
Prior art keywords: antagonist; solution; pain; inflammation; soluble receptor
Prior art date: 1998-11-05

Application number

AT99956954T

Other languages

English (en)

Inventor

Gregory Demopulos

Pamela Palmer

Jeffrey Herz

Original Assignee

Omeros Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-05

Filing date

1999-11-05

Publication date

2007-09-15

1999-11-05 Application filed by Omeros Corp filed Critical Omeros Corp

2007-09-15 Application granted granted Critical

2007-09-15 Publication of ATE372126T1 publication Critical patent/ATE372126T1/de

Links

238000000034 method Methods 0.000 title abstract 4
230000003110 anti-inflammatory effect Effects 0.000 title 1
206010061218 Inflammation Diseases 0.000 abstract 3
239000005557 antagonist Substances 0.000 abstract 3
230000004054 inflammatory process Effects 0.000 abstract 3
206010052428 Wound Diseases 0.000 abstract 2
208000027418 Wounds and injury Diseases 0.000 abstract 2
230000002401 inhibitory effect Effects 0.000 abstract 2
102000005962 receptors Human genes 0.000 abstract 2
108020003175 receptors Proteins 0.000 abstract 2
238000001356 surgical procedure Methods 0.000 abstract 2
229940127291 Calcium channel antagonist Drugs 0.000 abstract 1
229940122204 Cyclooxygenase inhibitor Drugs 0.000 abstract 1
102000016924 KATP Channels Human genes 0.000 abstract 1
108010053914 KATP Channels Proteins 0.000 abstract 1
102000000033 Purinergic Receptors Human genes 0.000 abstract 1
108010080192 Purinergic Receptors Proteins 0.000 abstract 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
239000000739 antihistaminic agent Substances 0.000 abstract 1
239000000480 calcium channel blocker Substances 0.000 abstract 1
BPKIGYQJPYCAOW-FFJTTWKXSA-I calcium;potassium;disodium;(2s)-2-hydroxypropanoate;dichloride;dihydroxide;hydrate Chemical compound O.[OH-].[OH-].[Na+].[Na+].[Cl-].[Cl-].[K+].[Ca+2].C[C@H](O)C([O-])=O BPKIGYQJPYCAOW-FFJTTWKXSA-I 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
238000007918 intramuscular administration Methods 0.000 abstract 1
238000001990 intravenous administration Methods 0.000 abstract 1
230000002262 irrigation Effects 0.000 abstract 1
238000003973 irrigation Methods 0.000 abstract 1
239000002756 mu opiate receptor agonist Substances 0.000 abstract 1
239000002742 neurokinin 1 receptor antagonist Substances 0.000 abstract 1
239000002746 neurokinin 2 receptor antagonist Substances 0.000 abstract 1
239000004036 potassium channel stimulating agent Substances 0.000 abstract 1
239000002599 prostaglandin synthase inhibitor Substances 0.000 abstract 1
239000003215 serotonin 5-HT2 receptor antagonist Substances 0.000 abstract 1
239000003369 serotonin 5-HT3 receptor antagonist Substances 0.000 abstract 1
239000000952 serotonin receptor agonist Substances 0.000 abstract 1
239000011780 sodium chloride Substances 0.000 abstract 1
238000007920 subcutaneous administration Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Surgery (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Cell Biology (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cosmetics (AREA)

AT99956954T 1998-11-05 1999-11-05 Spüllösung und verfahren zur schmerzlinderung und entzündungshemmung ATE372126T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10725698P	1998-11-05	1998-11-05

Publications (1)

Publication Number	Publication Date
ATE372126T1 true ATE372126T1 (de)	2007-09-15

Family

ID=22315706

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99956954T ATE372126T1 (de)	1998-11-05	1999-11-05	Spüllösung und verfahren zur schmerzlinderung und entzündungshemmung

Country Status (5)

Country	Link
EP (1)	EP1206275B1 (de)
AT (1)	ATE372126T1 (de)
AU (1)	AU1345000A (de)
DE (1)	DE69937070D1 (de)
WO (1)	WO2000025745A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7067144B2 (en)	1998-10-20	2006-06-27	Omeros Corporation	Compositions and methods for systemic inhibition of cartilage degradation
JP2003505427A (ja) *	1999-07-21	2003-02-12	オメロスコーポレイション	疼痛、炎症および軟骨分解の抑制のための溶液および方法
CN1697647A (zh) *	2002-02-01	2005-11-16	奥默罗斯公司	用于抑制疼痛,炎症和软骨退化的溶液及方法
CN101327325A (zh)	2002-07-30	2008-12-24	奥默罗斯公司	眼科冲洗液及方法
GB0319500D0 (en)	2003-08-19	2003-09-17	Resolution Chemicals Ltd	Particle-size reduction apparatus,and use thereof
GB0427568D0 (en)	2004-12-16	2005-01-19	Resolution Chemicals Ltd	Particle-size reduction apparatus, and the use thereof
EP2117538A1 (de)	2007-01-24	2009-11-18	Glaxo Group Limited	Pharmazeutische zusammensetzungen mit 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-)
AU2013201465B2 (en)	2012-10-24	2016-03-03	Rayner Intraocular Lenses Limited	Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI705812B (zh)	2014-12-01	2020-10-01	奥默羅斯公司	用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4968607A (en) *	1987-11-25	1990-11-06	Immunex Corporation	Interleukin-1 receptors
US5350683A (en) *	1990-06-05	1994-09-27	Immunex Corporation	DNA encoding type II interleukin-1 receptors
AU670125B2 (en) *	1992-09-15	1996-07-04	Immunex Corporation	Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists
US5844092A (en) *	1994-03-18	1998-12-01	Genentech, Inc.	Human TRK receptors and neurotrophic factor inhibitors
IT1274350B (it) *	1994-12-06	1997-07-17	Angeletti P Ist Richerche Bio	Antagonisti di interleuchina-6(il-6) che consistono di forme solubili del ricettore alfa di il-6, mutate nell'interfaccia che si lega a gp 130
KR100517210B1 (ko) *	1994-12-12	2006-06-07	오메로스 코포레이션	통증,염증및경련억제용관주용액
IL112834A (en) *	1995-03-01	2000-12-06	Yeda Res & Dev	Pharmaceutical compositions for controlled release of soluble receptors

1999
- 1999-11-05 AT AT99956954T patent/ATE372126T1/de not_active IP Right Cessation
- 1999-11-05 DE DE69937070T patent/DE69937070D1/de not_active Expired - Lifetime
- 1999-11-05 AU AU13450/00A patent/AU1345000A/en not_active Abandoned
- 1999-11-05 WO PCT/US1999/026330 patent/WO2000025745A2/en not_active Ceased
- 1999-11-05 EP EP99956954A patent/EP1206275B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69937070D1 (de)	2007-10-18
EP1206275A2 (de)	2002-05-22
EP1206275B1 (de)	2007-09-05
WO2000025745A3 (en)	2000-08-24
WO2000025745A2 (en)	2000-05-11
AU1345000A (en)	2000-05-22

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Legal Events

Date	Code	Title	Description
2008-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties