ATE372990T1 - Oxazolderivat und deren verwendung als insulinsensibilisatoren - Google Patents

Oxazolderivat und deren verwendung als insulinsensibilisatoren

Info

Publication number
ATE372990T1
ATE372990T1 AT03762516T AT03762516T ATE372990T1 AT E372990 T1 ATE372990 T1 AT E372990T1 AT 03762516 T AT03762516 T AT 03762516T AT 03762516 T AT03762516 T AT 03762516T AT E372990 T1 ATE372990 T1 AT E372990T1
Authority
AT
Austria
Prior art keywords
insulin sensitizers
oxazole derivatives
oxazole
sensitizers
insulin
Prior art date
Application number
AT03762516T
Other languages
English (en)
Inventor
Bernd Brodbeck
Hans Hilpert
Roland Humm
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE372990T1 publication Critical patent/ATE372990T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03762516T 2002-07-03 2003-06-26 Oxazolderivat und deren verwendung als insulinsensibilisatoren ATE372990T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02014828 2002-07-03

Publications (1)

Publication Number Publication Date
ATE372990T1 true ATE372990T1 (de) 2007-09-15

Family

ID=29797151

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03762516T ATE372990T1 (de) 2002-07-03 2003-06-26 Oxazolderivat und deren verwendung als insulinsensibilisatoren

Country Status (16)

Country Link
US (1) US6747049B2 (de)
EP (1) EP1519925B1 (de)
JP (1) JP4290648B2 (de)
KR (1) KR100621294B1 (de)
CN (1) CN100402510C (de)
AR (1) AR040359A1 (de)
AT (1) ATE372990T1 (de)
AU (1) AU2003249879B2 (de)
BR (1) BR0312452A (de)
CA (1) CA2490152C (de)
DE (1) DE60316290T2 (de)
ES (1) ES2291688T3 (de)
MX (1) MXPA04012840A (de)
PL (1) PL374818A1 (de)
RU (1) RU2295520C2 (de)
WO (1) WO2004005266A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2277142T3 (es) * 2002-08-30 2007-07-01 Japan Tobacco Inc. Compuesto de dibencilamina y su uso medicinal.
CN101007790B (zh) * 2006-01-27 2011-03-30 北京摩力克科技有限公司 草氨酸衍生物、其制备方法和医药用途
CA2640608A1 (en) * 2006-02-01 2007-08-09 Merck & Co., Inc. Potassium channel inhibitors
US20190350955A1 (en) 2016-06-30 2019-11-21 Inserm (Institut National De La Sante Et De La Recherche Medicale Methods and pharmaceutical compositions for the treatment of cardiomyopathies
WO2020201263A1 (en) 2019-04-01 2020-10-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment and prevention of cardiac remodeling

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011326A (en) 1975-07-29 1977-03-08 Merck & Co., Inc. 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
TW222626B (de) * 1991-07-22 1994-04-21 Pfizer
GB9225386D0 (en) 1992-12-04 1993-01-27 Smithkline Beecham Plc Novel compounds
DE4317320A1 (de) 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
GB9326171D0 (en) 1993-12-22 1994-02-23 Smithkline Beecham Plc Novel compounds
GB9600464D0 (en) 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
ZA9711051B (en) 1996-12-10 1999-06-09 Bristol Myers Squibb Co Benzodioxole benzofuran dihydrobenzofuran and benzodioxane melatonergic agents
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
US6121397A (en) 1997-07-14 2000-09-19 Xerox Corporation Polymerization processes using oligomeric compound, monomer and surfactant
HN1998000118A (es) 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.
DE69815008T2 (de) 1997-09-19 2004-04-01 Ssp Co., Ltd. Alfa-substituierte Phenylpropionsäurederivate und diese enthaltende Arzneimittel
EP1073643B1 (de) 1998-04-23 2004-12-29 Dr. Reddy's Laboratories Ltd. Heterozyklische verbindungen,und deren verwendung in arzneimittel,verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
GB9817118D0 (en) 1998-08-07 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds
GB9914977D0 (en) * 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
PT1078923E (pt) 1999-08-02 2006-07-31 Hoffmann La Roche Processo para a preparacao de derivados de benzotiofeno
US6930120B2 (en) 2000-08-23 2005-08-16 Eli Lilly And Company Oxazolyl-arylproplonic acid derivatives and their use as ppar agonists

Also Published As

Publication number Publication date
JP4290648B2 (ja) 2009-07-08
KR20050025303A (ko) 2005-03-14
RU2295520C2 (ru) 2007-03-20
MXPA04012840A (es) 2005-02-24
JP2005535647A (ja) 2005-11-24
EP1519925B1 (de) 2007-09-12
AU2003249879B2 (en) 2008-12-18
AU2003249879A1 (en) 2004-01-23
EP1519925A1 (de) 2005-04-06
CA2490152C (en) 2009-04-07
DE60316290T2 (de) 2008-06-12
US20040006116A1 (en) 2004-01-08
CN1668606A (zh) 2005-09-14
BR0312452A (pt) 2005-04-19
CA2490152A1 (en) 2004-01-15
RU2005102817A (ru) 2005-11-20
AR040359A1 (es) 2005-03-30
US6747049B2 (en) 2004-06-08
WO2004005266A1 (en) 2004-01-15
KR100621294B1 (ko) 2006-09-06
PL374818A1 (en) 2005-10-31
CN100402510C (zh) 2008-07-16
ES2291688T3 (es) 2008-03-01
DE60316290D1 (de) 2007-10-25

Similar Documents

Publication Publication Date Title
CY2013027I2 (el) Νεα παραγωγα ινσουλινης
ATE395339T1 (de) Biphenylderivate und deren verwendung als fungizide
ATE426597T1 (de) Benzamidderivate und deren verwendung als glucokinaseaktivierende mittel
ATE346056T1 (de) Substituierte phenylacetamide und deren verwendung als glucokinaseaktivatoren
ATE403654T1 (de) Benzimidazol-, benzothiazol- und benzoxazolderivate und deren verwendung als lta4h-modulatoren
ATE430145T1 (de) 3-ä(2-ä 4-(hexyloxycarbonylamino-imino-methyl)- phenylaminoü-methylü-1-methyl-1h-benzimidazol-5 carbonyl)-pyridin-2-yl-aminoü -propionsäure- ethylester -methansulfonat und dessen verwendung als arzneimittel
DE50312295D1 (de) 8-ä3-amino-piperidin-1-ylü -xanthine, deren herstellung und deren verwendung als arzneimittel
DE60335151D1 (de) Pyrimidinderivate und deren Verwendung als CB2-Modulatoren
DE60202876D1 (de) 6 aryl 4 aminopicolinate und deren verwendung als herbizide
DE60328087D1 (de) Aryl substituierte pyrimidine und deren verwendung
ATE381335T1 (de) 2-cyanopyrrolopyrimidine und deren pharmazeutische verwendung
DE60303440D1 (de) Benzoxazinonderivate, deren herstellung und deren verwendung als medikamente
DE60323754D1 (de) Dioxan-2-alkylkarbamaten derivaten, deren herstellung und deren therapeutischen verwendung
EP1469860A4 (de) Antikrebskombination und deren verwendung
ATE316523T1 (de) Benzoxazinderivate als 5-ht6-modulatoren und deren verwendungen
DE50206476D1 (de) Cyanoanthranylamid-derivate und deren verwendung als arzneimittel
ATE371653T1 (de) Benzoxazinderivate und deren verwendungen
DE602004010284D1 (de) Aminochinolinderivate und deren verwendung als adenosin-a3-liganden
DE60311598D1 (de) Naphthyridin-derivate und ihre verwendung als fungizide
DE60322926D1 (de) Photopolymerisierbare zusammensetzung und verwendung davon
ATE555097T1 (de) 4-cycloalkyl-substituierte tetrahydrochinolinderivate und deren verwendung als medikamente
DE50313185D1 (de) 2-pyrrolidin-2-yl-ä1,3,4ü -oxadiazol-derivate und ihre verwendung als antidepressiva
ATE372990T1 (de) Oxazolderivat und deren verwendung als insulinsensibilisatoren
DE602004022169D1 (de) Tetrahydrocarbazolderivate und deren pharmazeutische verwendung
EP1553101A4 (de) N-acetylglucosaminderivate und deren verwendung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1519925

Country of ref document: EP