ATE373483T1 - Zusammensetzung zur behandlung von prostatakrebs - Google Patents

Zusammensetzung zur behandlung von prostatakrebs

Info

Publication number
ATE373483T1
ATE373483T1 AT00989699T AT00989699T ATE373483T1 AT E373483 T1 ATE373483 T1 AT E373483T1 AT 00989699 T AT00989699 T AT 00989699T AT 00989699 T AT00989699 T AT 00989699T AT E373483 T1 ATE373483 T1 AT E373483T1
Authority
AT
Austria
Prior art keywords
prostate cancer
composition
treating prostate
living mammal
glycosidase
Prior art date
Application number
AT00989699T
Other languages
English (en)
Inventor
Muharrem Gokcen
Original Assignee
Immunolytics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunolytics Inc filed Critical Immunolytics Inc
Application granted granted Critical
Publication of ATE373483T1 publication Critical patent/ATE373483T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
AT00989699T 1999-10-28 2000-10-25 Zusammensetzung zur behandlung von prostatakrebs ATE373483T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/428,375 US6428785B1 (en) 1999-10-28 1999-10-28 Method and composition for treating prostate cancer

Publications (1)

Publication Number Publication Date
ATE373483T1 true ATE373483T1 (de) 2007-10-15

Family

ID=23698630

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00989699T ATE373483T1 (de) 1999-10-28 2000-10-25 Zusammensetzung zur behandlung von prostatakrebs

Country Status (9)

Country Link
US (2) US6428785B1 (de)
EP (1) EP1242110B1 (de)
JP (1) JP2003513931A (de)
CN (1) CN1176714C (de)
AT (1) ATE373483T1 (de)
AU (1) AU2617901A (de)
CA (1) CA2389176A1 (de)
DE (1) DE60036490T2 (de)
WO (1) WO2001034176A1 (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595199B1 (en) * 1998-07-31 2009-09-29 Max-Planck-Gesellschaft zur Förderung der Wissenchaften e.V. Method of detecting amyloid-like fibrils or protein aggregates
ES2424348T3 (es) * 2002-06-24 2013-10-01 Incept, Llc Cargas y métodos para desplazar tejidos para mejorar los resultados radiológicos
AU2003298972A1 (en) * 2003-07-14 2005-02-04 Dmitry Dmitrievich Genkin Method for treating oncological, virulent and somatic diseases, method for controlling treatment efficiency, pharmaceutical agents and composition for carrying out said treatment
WO2006130034A1 (fr) * 2005-04-25 2006-12-07 Dmitry Dmitrievich Genkin Procede pour prolonger la duree de vie d'animaux ou de l'humain
US8388951B2 (en) 2003-07-14 2013-03-05 Cls Therapeutics Limited Method for treating systemic DNA mutation disease
US9248166B2 (en) 2003-07-14 2016-02-02 Cls Therapeutics Limited Method for treating oncological diseases
US8431123B2 (en) * 2003-07-14 2013-04-30 Cls Therapeutics Limited Method for treating systemic bacterial, fungal and protozoan infection
US8710012B2 (en) * 2003-07-14 2014-04-29 Cls Therapeutics Limited Method for treating oncological diseases
GB2408207A (en) * 2003-11-24 2005-05-25 Johnson & Johnson Medical Ltd Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme
MXPA03011987A (es) * 2003-12-19 2005-06-23 Osio Sancho Alberto Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
WO2005080589A1 (en) * 2004-02-19 2005-09-01 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 3 (klk3)
WO2005097149A2 (en) * 2004-04-09 2005-10-20 Nicholas Piramal India Limited Herbal extract for renal disorders
JP2008505853A (ja) 2004-04-13 2008-02-28 クインテセンス バイオサイエンシーズ インコーポレーティッド 細胞傷害性薬剤としての非天然のリボヌクレアーゼ複合体
ES2509872T3 (es) 2005-03-03 2014-10-20 Allergan, Inc. Procedimientos para obtener una toxina clostrídica
JP3989936B2 (ja) * 2005-04-07 2007-10-10 進 須永 抗腫瘍剤及び新規dnアーゼ
CA2633980A1 (en) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Improved composition for collecting and preserving placental stem cells and methods of using the composition
US8840882B2 (en) * 2006-06-23 2014-09-23 Quintessence Biosciences, Inc. Modified ribonucleases
WO2008010991A2 (en) 2006-07-17 2008-01-24 Quintessence Biosciences, Inc. Methods and compositions for the treatment of cancer
US20080027554A1 (en) * 2006-07-31 2008-01-31 Talmadge Karen D Kit and methods of treatment of an intervertebral disc
US8871200B2 (en) * 2006-11-28 2014-10-28 Cls Therapeutics Limited Method for treating human diseases associated with an increased deoxyribonucleic acid content in extracellular spaces of tissues and a medicinal preparation for carrying out said method
CA2678038C (en) 2007-02-15 2016-10-11 Allergan, Inc. Use of botulinum toxin and enzymes for treating bladder or prostate disorders, or hyperhydrosis
CN101313926B (zh) * 2007-05-30 2012-12-26 中央研究院 转录调控物组合物
PL2187965T3 (pl) 2007-08-17 2020-05-18 Purdue Research Foundation Koniugaty wiążący psma ligand-łącznik i sposoby ich zastosowania
WO2009048909A1 (en) * 2007-10-08 2009-04-16 Quintessence Biosciences, Inc. Compositions and methods for ribonuclease-based therapies
CA2734446C (en) 2008-08-22 2017-06-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
BRPI0920743A2 (pt) 2008-10-01 2016-09-20 Quintessence Biosciences Inc ribonucleases terapeuticas
WO2010138918A1 (en) * 2009-05-29 2010-12-02 Pacira Pharmaceuticals, Inc. Hyaluronidase as an adjuvant for increasing the injection volume and dispersion of large diameter synthetic membrane vesicles containing a therapeutic agent
CA3149284A1 (en) 2009-12-15 2011-07-14 Incept, Llc Implants and biodegradable fiducial markers
US9951324B2 (en) 2010-02-25 2018-04-24 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
US8557777B2 (en) 2010-07-09 2013-10-15 The Board Of Trustees Of The University Of Illinois Methods for treating cancer using prostate specific antigen and tumor endothelial marker peptides
WO2012006634A2 (en) * 2010-07-09 2012-01-12 The Board Of Trustees Of The University Of Illiniois Prostate specific antigen (psa) peptide therapy
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
WO2012109387A1 (en) 2011-02-08 2012-08-16 Halozyme, Inc. Composition and lipid formulation of a hyaluronan-degrading enzyme and the use thereof for treatment of benign prostatic hyperplasia
JP6104896B2 (ja) 2011-06-01 2017-03-29 アントフロゲネシス コーポレーション 胎盤幹細胞を使用する疼痛の治療
WO2013091657A1 (en) * 2011-12-22 2013-06-27 Herlev Hospital Therapeutic applications of calcium electroporation to effectively induce tumor necrosis
DK2883104T3 (da) 2012-08-10 2024-07-29 Osio Corp D/B/A Yolia Health Anvendelse af kontaktlinse ved behandling af en ofthalmologisk lidelse
EA201590783A1 (ru) 2012-11-15 2015-11-30 Эндосайт, Инк. Конъюгаты для доставки лекарственных средств и способы лечения заболеваний, вызванных клетками, экспрессирующими psma
EP3456700A1 (de) 2013-10-18 2019-03-20 Deutsches Krebsforschungszentrum Markierte inhibitoren des prostataspezifischen membranantigens (psma), deren verwendung als kontrastmittel und pharmazeutika zur behandlung von prostatakrebs
EP3533473A3 (de) 2013-11-14 2019-12-18 Endocyte, Inc. Verbindungen für positronenemissionstomografie
CZ307195B6 (cs) * 2013-11-18 2018-03-14 František Trnka Farmaceutická kompozice obsahující směs proenzymů a enzymů
WO2015140802A2 (en) * 2014-03-20 2015-09-24 Technion Research & Development Foundation Limited Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof
US12144519B2 (en) 2014-04-03 2024-11-19 Corbin Clinical Resources, Llc Transperineal prostate biopsy and treatment methods
US10743909B2 (en) 2014-04-03 2020-08-18 Corbin Clinical Resources, Llc Transperineal prostate biopsy device, systems, and methods of use
US10064681B2 (en) 2014-04-03 2018-09-04 Corbin Clinical Resources, Llc Method, system, and device for planning and performing, guided and free-handed transperineal prostate biopsies
US10617743B2 (en) 2014-06-19 2020-04-14 Cls Therapeutics Limited Method to improve safety and efficacy of anti-cancer therapy
GB2528304B (en) * 2014-07-17 2020-05-13 Cambridge Univ Hospitals Nhs Foundation Trust Perineal prostate biopsy apparatus
WO2016025922A1 (en) * 2014-08-14 2016-02-18 Dana-Farber Cancer Institute, Inc. Coated particles for drug delivery
CN105477627B (zh) * 2014-09-19 2021-04-30 山东蓝金生物工程有限公司 治疗前列腺癌的组合物及其用途
KR101683635B1 (ko) 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
US10188759B2 (en) 2015-01-07 2019-01-29 Endocyte, Inc. Conjugates for imaging
ES2799515T3 (es) 2015-05-22 2020-12-18 Dmitry Dmitrievich Genkin ADN extracelular como una diana terapéutica en la neurodegeneración
WO2017074257A1 (en) * 2015-10-26 2017-05-04 Nanyang Technological University Non-viable derivatives of clostridium sporogenes as anti-cancer therapeutic agents
CN105255825B (zh) * 2015-11-16 2019-07-19 广州赛莱拉干细胞科技股份有限公司 一种跟腱来源肌腱干细胞原代分离消化液及分离方法
AU2019209770B2 (en) 2018-01-16 2025-07-31 Cls Therapeutics Limited Treatment of diseases by liver expression of an enzyme which has a deoxyribonuclease (DNase) activity
WO2019145950A1 (en) 2018-01-23 2019-08-01 Technion Research & Development Foundation Limited Collagenase loaded liposomes for enhancing drug delivery
CN112368024A (zh) 2018-04-17 2021-02-12 恩多塞特公司 治疗癌症的方法
EP3698806A1 (de) * 2019-02-19 2020-08-26 Fundacion Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz Chemisches skalpell
CN114096264B (zh) 2019-05-20 2025-03-14 因多塞特股份有限公司 制备psma缀合物的方法
CN111705051A (zh) * 2020-07-28 2020-09-25 金紫晶(南京)生物医药技术有限公司 一种复合消化酶及复合消化酶冻干粉
CN112941009B (zh) * 2021-02-22 2024-03-01 新格元(南京)生物科技有限公司 一种ffpe样本预处理液及从ffpe样本中分离单细胞的方法
CN115671267A (zh) * 2021-07-23 2023-02-03 上海宝济药业有限公司 一种皮下抗生素药物组合物
CN117258047B (zh) * 2023-10-12 2024-06-18 成都世联康健生物科技有限公司 一种猪牙髓组织脱细胞外基质水凝胶及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524065A (en) 1983-08-04 1985-06-18 Bio-Specifics N.V. Method for the prevention and treatment of scars with enzymes
US4645668A (en) 1983-08-04 1987-02-24 Biospecifics, Nv Method for the prevention and treatment of scars with enzymes
US4678668A (en) 1985-10-28 1987-07-07 Md Associates Method of reducing soft tissue swelling and pain
US4978332A (en) 1987-09-28 1990-12-18 Matrix Pharmaceutical, Inc. Treatments employing vasoconstrictive substances in combination with cytotoxic agents for introduction into cellular lesion areas
US5116615A (en) 1989-01-27 1992-05-26 Immunolytics, Inc. Method for treating benign prostatic hypertrophy
HK1003981A1 (en) * 1989-01-27 1998-11-13 Immunolytics, Inc. Composition and method for treating benign prostatic hypertrophy
US5162115A (en) 1989-05-09 1992-11-10 Pietronigro Dennis D Antineoplastic solution and method for treating neoplasms
US5051257A (en) 1989-05-09 1991-09-24 Pietronigro Dennis D Antineoplastic solution and method for treating neoplasms
US5958406A (en) * 1994-11-22 1999-09-28 Phairson Medical Inc. Acne treatment with multifunctional enzyme
US5422261A (en) 1993-04-16 1995-06-06 Baxter International Inc. Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells
JPH09508892A (ja) 1993-11-17 1997-09-09 マサチューセッツ インスティテュート オブ テクノロジー ヘパリナーゼを用いる血管形成の阻害方法
CA2189646C (en) 1994-06-24 1999-05-25 Francis E. Dwulet A purified mixture of collagenases and two other proteases obtained from clostridium histolyticum
US5658730A (en) 1994-12-23 1997-08-19 Ctrc Research Foundation Methods of human prostate cancer diagnosis
US5854206A (en) 1995-08-25 1998-12-29 Corixa Corporation Compounds and methods for treatment and diagnosis of prostate cancer
AU7130696A (en) 1995-09-19 1997-04-09 Schering Aktiengesellschaft Combination of beta-interferon for the treatment of prostate cancer
US5783182A (en) 1996-01-30 1998-07-21 Baylor College Of Medicine Method for identifying metastatic sequences
US5780435A (en) 1995-12-15 1998-07-14 Praecis Pharmaceuticals Incorporated Methods for treating prostate cancer with LHRH-R antagonists
US5989888A (en) 1996-01-24 1999-11-23 Roche Diagnostics Corporation Purified mixture of collagenase I, collagenase II and two other proteases
US5716541A (en) 1996-09-23 1998-02-10 Bayer Corporation Azeotrope-like compositions of 1,1,1,3,3 pentafluoropropane and tetramethylsilane
US5830741A (en) 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease

Also Published As

Publication number Publication date
DE60036490D1 (de) 2007-10-31
CA2389176A1 (en) 2001-05-17
US6428785B1 (en) 2002-08-06
EP1242110A1 (de) 2002-09-25
US20020106359A1 (en) 2002-08-08
WO2001034176A1 (en) 2001-05-17
CN1384754A (zh) 2002-12-11
JP2003513931A (ja) 2003-04-15
US6913744B2 (en) 2005-07-05
US20020061300A1 (en) 2002-05-23
AU2617901A (en) 2001-06-06
DE60036490T2 (de) 2008-06-19
EP1242110B1 (de) 2007-09-19
CN1176714C (zh) 2004-11-24

Similar Documents

Publication Publication Date Title
DE60036490D1 (de) Zusammensetzung zur behandlung von prostatakrebs
ATE255418T1 (de) Neurotoxine zur behandlung von pankreatischen krankheiten
MEP26808A (en) The use of substituted azetidinone compounds for the treatment of sitosterolemia
TR199801151T2 (xx) Trombin inhibit�r� �n ila�lar.
DK0719154T3 (da) Aktiveret faktor VIII som terapeutisk middel og metode til behandling af faktor VIII-mangel
ATE543509T1 (de) Material und verfahren zur förderung der reparatur von nervengewebe
ATE518540T1 (de) Beta-lactam verbindung enthaltende neurotherapeutische zusammensetzung
DE60042153D1 (de) Pharmauzetisch zusammensetzung nitratenquelle und ansäuerungsmitteln enthaltende zur behandlung von offenen wunden und verbrennungen
MX9606386A (es) Agentes que afectan la hemostasis trombotica.
ATE121946T1 (de) Zusammensetzung und verfahren für die behandlung gutartiger prostata-hypertrophie.
DE60139078D1 (de) Plasminogen aktivator zur verhinderung von horn- und subepithelialeintrübung nach laser-sehkraftkorrektur-chirurgie
EP1226109A4 (de) Phenylamin-carbonsäure-verbindungen und zubereitungen zur verabreichung von wirkstoffen
EP1098642A4 (de) Verfahren zur behandlung von zustanden moduliert durch lactosylceramiden
ES2082198T3 (es) Inhibidores de esteroide-sulfatasa.
MXPA02009904A (es) Derivados de apomorfina y metodos para su uso.
HK1049115A1 (zh) 治療過敏性失調的成分和方法
ATE385807T1 (de) Pharmazeutische verbindung und methoden zur behandlung von menschlichen karzinomen mittels arginin entzug
ATE255904T1 (de) Fibrin-/fibrinogen-abbau und gerinsel-auflösung durch eine fibrinolytische matrix- metallproteinase
ATE368455T1 (de) Verwendung von (+)-tramadol, o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz
ATE277943T1 (de) Trypsininhibitoren
AU5170400A (en) Topical application of muscarinic and opioid agents for treatment of tinnitus
ATE230609T1 (de) Verfahren zur behandlung von entzündungen und zusammensetzungen dafür
ATE493147T1 (de) Pharmazeutische zusammensetzungen und methoden nützlich zur behandlung von krebs oder leberfibrose
ATE321045T1 (de) Methoden und zusammensetzungen zur behandlung von schmerzen
ES2284528T3 (es) Utilizacion de elastasa para abrir arterias y venas obstruidas.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties