ATE373486T1 - Impfstoffe zur behandlung von kolonkrebs - Google Patents

Impfstoffe zur behandlung von kolonkrebs

Info

Publication number
ATE373486T1
ATE373486T1 AT01102609T AT01102609T ATE373486T1 AT E373486 T1 ATE373486 T1 AT E373486T1 AT 01102609 T AT01102609 T AT 01102609T AT 01102609 T AT01102609 T AT 01102609T AT E373486 T1 ATE373486 T1 AT E373486T1
Authority
AT
Austria
Prior art keywords
hormone
fragment
epitope
immunologically equivalent
peptide
Prior art date
Application number
AT01102609T
Other languages
English (en)
Inventor
Vernon C Stevens
Original Assignee
Univ Ohio State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio State Res Found filed Critical Univ Ohio State Res Found
Application granted granted Critical
Publication of ATE373486T1 publication Critical patent/ATE373486T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0006Contraceptive vaccins; Vaccines against sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001144Hormones, e.g. calcitonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/5555Muramyl dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT01102609T 1992-09-30 1992-09-30 Impfstoffe zur behandlung von kolonkrebs ATE373486T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1992/008370 WO1994007530A1 (en) 1992-09-30 1992-09-30 Vaccines and antigenic conjugates

Publications (1)

Publication Number Publication Date
ATE373486T1 true ATE373486T1 (de) 2007-10-15

Family

ID=25677857

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01102609T ATE373486T1 (de) 1992-09-30 1992-09-30 Impfstoffe zur behandlung von kolonkrebs

Country Status (7)

Country Link
EP (2) EP1129724B1 (de)
JP (1) JPH08502062A (de)
AT (1) ATE373486T1 (de)
AU (1) AU679902B2 (de)
CA (1) CA2145391A1 (de)
DE (1) DE69233711D1 (de)
WO (1) WO1994007530A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
GB9514816D0 (en) 1995-07-19 1995-09-20 Ucli Ltd Substances and their medical use
US7135457B1 (en) 1997-05-15 2006-11-14 Cytogen Corporation Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
US7053177B1 (en) 1997-05-15 2006-05-30 Cytogen Corporation Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
US6703362B1 (en) 1997-05-15 2004-03-09 Cytogen Corporation Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
JP2002534478A (ja) * 1998-12-18 2002-10-15 エイブイアイ バイオファーマ, インコーポレイテッド 絨毛性ゴナドトロピンdnaワクチンおよび方法
JP4658423B2 (ja) * 1999-08-03 2011-03-23 ザ オハイオ ステイト ユニバーシティ Her−2タンパク質に対する免疫反応性を増強するためのポリペプチドおよびポリヌクレオチド
RU2172182C1 (ru) * 2000-07-27 2001-08-20 Бритов Василий Александрович Способ профилактики и лечения заболеваний иммунной системы и средство для его осуществления
JP2005508838A (ja) 2001-03-23 2005-04-07 アフトン コーポレーション 膵癌の組合せ治療
US20090191232A1 (en) 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
WO2004088326A2 (en) 2003-03-28 2004-10-14 Aphton Corporation Gastrin hormone immunoassays
EP1794586B1 (de) 2004-09-22 2013-01-30 Cancer Advances, Inc., Monoklonale antikörper gegen progastrin
JP2008528643A (ja) * 2005-02-04 2008-07-31 スルバック アーぺーエス サバイビンペプチドワクチン
US7691396B2 (en) 2005-06-15 2010-04-06 The Ohio State University Research Foundation Chimeric peptides comprising HER-2 B-cell epitopes and measles virus fusion protein T-cell epitopes
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
EP2496255A4 (de) * 2009-11-05 2014-03-26 Mercia Pharma Inc Adjuvierter influenza-impfstoff in nanopartikelform
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
KR102772810B1 (ko) 2017-06-15 2025-02-28 캔서 어드밴시스 아이엔씨 종양 및 암에 대한 체액성 및 세포 면역을 유도하기 위한 조성물 및 방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4691006A (en) * 1983-03-04 1987-09-01 Ohio State University Antigenic modification of polypeptides
US4526716A (en) * 1981-11-20 1985-07-02 The Ohio State University Antigenic modification of polypeptides
US4762913A (en) * 1973-05-07 1988-08-09 The Ohio State University Antigenic modification of polypeptides
US5006334A (en) * 1973-05-07 1991-04-09 The Ohio State University Antigenic modification of polypeptides
US4201770A (en) * 1973-05-07 1980-05-06 The Ohio State University Antigenic modification of polypeptides
US4384995A (en) * 1980-01-16 1983-05-24 The Ohio State University Antigenic modification of polypeptides
US4302386A (en) * 1978-08-25 1981-11-24 The Ohio State University Antigenic modification of polypeptides
US4310455A (en) * 1979-04-17 1982-01-12 Research Corporation Antigen for early pregnancy test and contraceptive vaccine
US4855285A (en) * 1985-12-04 1989-08-08 The Ohio State University Research Foundation Antigenic modification of polypeptides
US4882145A (en) * 1986-12-09 1989-11-21 Scripps Clinic And Research Foundation T cell epitopes of the hepatitis B virus nucleocapsid protein
US4886782A (en) * 1987-02-26 1989-12-12 The United States Of America As Represented By The Department Of Health And Human Services Malarial immunogen
FR2649013B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
IT1237764B (it) * 1989-11-10 1993-06-17 Eniricerche Spa Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.

Also Published As

Publication number Publication date
EP0662839A1 (de) 1995-07-19
EP0662839A4 (de) 1995-09-06
AU679902B2 (en) 1997-07-17
WO1994007530A1 (en) 1994-04-14
EP1129724B1 (de) 2007-09-19
EP1129724A2 (de) 2001-09-05
JPH08502062A (ja) 1996-03-05
DE69233711D1 (de) 2007-10-31
AU2806392A (en) 1994-04-26
EP1129724A3 (de) 2001-11-07
CA2145391A1 (en) 1994-04-14

Similar Documents

Publication Publication Date Title
DE69233711D1 (de) Impfstoffe zur Behandlung von Kolonkrebs
PT92938A (pt) Imunogenes e processo para a preparacao de composicoes imunogenicas contra os peptidos da gastrina
RU95105991A (ru) Конъюгат, вакцина, способы усиления иммуногенности, способы иммунизации
GB2303855B (en) Helicobacter pylori antigenic protein preparation and immunoassays
DE69939706D1 (de) Verbesserte adjuvant zusammensetzungen auf basis von saponin und damit zusammenhängende methoden
EP0680338A4 (de) Konjugatimpfstoffe von gangliosid-klh mit qs-21.
DK521584A (da) Antigener, modificerede antigener og antigent modificerede polypeptider, fremgangsmaade til fremstilling heraf og vacciner indeholdende disse
BR9605153B1 (pt) vacina de combinação, e, kit de vacinação.
KR937000146A (ko) 거세되지 않은 수컷 가축의 고기의 관능적 품질을 개선하기 위한 방법, 이 방법에 이용 가능한 백신, 특히 그 백신을 생산하기 위한 신규의 펩티드 및 그에 관계된 백신반응 키트
GR3020610T3 (en) Monoclonal antibodies against tumor associated antigen, their preparation and use
NO883306D0 (no) Farmasoeytisk aktive konjugater med forbedret bindingsspesifisitet for kroppsvev.
EP0495008A4 (en) Method of treatment
NZ314585A (en) Method of treating H. Pylori associated gastroduodenal disease
ATE185148T1 (de) Lipopeptide, t-cytotoxische lymphocyte aktivierend, und deren verwendung als vakzine
ATE261314T1 (de) P53 impfstoff
GR3029727T3 (en) Synthetic peptides and vaccines against parvovirus.
DK543988A (da) Fremgangsmaade til behandling af infertilitet og middel til anvendelse ved fremgangsmaaden
ATE134705T1 (de) Rekombinantes hyopneumoniae antigen und dessen verwendung
DK0623170T3 (da) Vacciner baseret på streptokinase
EP0282501A1 (de) Regulierung der tierreproduktion
BR9306187A (pt) Vacina bacterin-toxóide pasteurella haemolytica tipo a-1
DE69322960D1 (de) Empfängnisverhütender impfstoff
DE69012328D1 (de) Srif-verwandte peptide und deren verwendungen.
Kocken Recombinant fusion proteins of herpes simplex virus type 1 glycoprotien D; expression in Escherichia col, purification and immunological properties
RU96123906A (ru) Способ и вакцина для профилактики и лечения иммунодефицитов, например рака

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties