ATE374024T1 - Verwendung von 5-methoxytryptamin als kardioprotektives mittel - Google Patents
Verwendung von 5-methoxytryptamin als kardioprotektives mittelInfo
- Publication number
- ATE374024T1 ATE374024T1 AT04745141T AT04745141T ATE374024T1 AT E374024 T1 ATE374024 T1 AT E374024T1 AT 04745141 T AT04745141 T AT 04745141T AT 04745141 T AT04745141 T AT 04745141T AT E374024 T1 ATE374024 T1 AT E374024T1
- Authority
- AT
- Austria
- Prior art keywords
- methoxytryptamine
- cardioprotective agent
- prevention
- treatment
- tissue damage
- Prior art date
Links
- JTEJPPKMYBDEMY-UHFFFAOYSA-N 5-methoxytryptamine Chemical compound COC1=CC=C2NC=C(CCN)C2=C1 JTEJPPKMYBDEMY-UHFFFAOYSA-N 0.000 title abstract 6
- 229940097276 5-methoxytryptamine Drugs 0.000 title abstract 3
- 229940045200 cardioprotective agent Drugs 0.000 title 1
- 239000012659 cardioprotective agent Substances 0.000 title 1
- 210000005003 heart tissue Anatomy 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000000451 tissue damage Effects 0.000 abstract 2
- 231100000827 tissue damage Toxicity 0.000 abstract 2
- 229940123457 Free radical scavenger Drugs 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- -1 oxygen radicals Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002516 radical scavenger Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/627,398 US20050020666A1 (en) | 2003-07-25 | 2003-07-25 | Cardioprotective agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE374024T1 true ATE374024T1 (de) | 2007-10-15 |
Family
ID=34080633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04745141T ATE374024T1 (de) | 2003-07-25 | 2004-07-19 | Verwendung von 5-methoxytryptamin als kardioprotektives mittel |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20050020666A1 (de) |
| EP (1) | EP1653948B1 (de) |
| AT (1) | ATE374024T1 (de) |
| DE (1) | DE602004009197D1 (de) |
| WO (1) | WO2005009419A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008092084A2 (en) | 2007-01-26 | 2008-07-31 | Centocor, Inc. | Injectable non-aqueous suspension with high concentration of therapeutic agent |
| EP2140265B1 (de) * | 2007-03-22 | 2012-10-31 | Scandinavian Micro Biodevices A/S | Durchflusssystem, durchflussvorrichtung und verfahren zur durchführung eines tests |
| EP2307141B1 (de) | 2008-07-29 | 2019-02-20 | Scandinavian Micro Biodevices ApS | Mikrofluidische vorrichtung |
| US10792331B2 (en) * | 2015-09-09 | 2020-10-06 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Methods for reducing cardiotoxicity from chemotherapy by administering humanin analog compositions |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU227537A1 (en) * | 1960-09-19 | 1978-06-15 | P G Zherebchenko | Medicine |
| EP0330625B1 (de) * | 1988-02-25 | 1995-12-20 | I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi | Verfahren zur totalen Synthese von einer Indol-Struktur-Verbindungsklasse des Tryptamin-Typs, insbesondere Melatonin- oder N-Acetyl-5-methoxytryptamin mit hoher Reinheit und Löslichkeit, verwendbar in der AIDS-Therapie |
| US5405863A (en) * | 1992-12-01 | 1995-04-11 | Smithkline Beecham Corporation | Antioxidant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds |
| HUP9800731A3 (en) * | 1995-03-06 | 2000-03-28 | Novo Nordisk As | Stimulation of meiosis |
| FR2751539B1 (fr) * | 1996-07-25 | 1998-12-04 | Oreal | Nouvelles compositions topiques comprenant de tres faibles doses de melatonine ou ses derives et leur utilisation en cosmetique |
| US5885293A (en) * | 1997-03-03 | 1999-03-23 | Innovasive Devices, Inc. | Apparatus and method for cutting a surface at a repeatable angle |
| AU5168700A (en) * | 1999-05-28 | 2000-12-18 | Synaptic Pharmaceutical Corporation | Dna encoding snorf33 receptor |
| PT1272177E (pt) * | 2000-01-05 | 2007-07-11 | Neurim Pharma 1991 | Método e formulação para o tratamento da resistência aos antihipertensos e condições associadas. |
| JP2005524601A (ja) * | 2000-09-15 | 2005-08-18 | ザ スクリップス リサーチ インスティテュート | 抗体による過酸化水素およびスーパーオキシド生成に関する方法および組成物 |
| WO2002038141A2 (en) * | 2000-11-08 | 2002-05-16 | Massachusetts Institute Of Technology | Compositions and methods for treatment of mild cognitive impairment |
| US20040147581A1 (en) * | 2002-11-18 | 2004-07-29 | Pharmacia Corporation | Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy |
-
2003
- 2003-07-25 US US10/627,398 patent/US20050020666A1/en not_active Abandoned
-
2004
- 2004-07-19 AT AT04745141T patent/ATE374024T1/de not_active IP Right Cessation
- 2004-07-19 EP EP04745141A patent/EP1653948B1/de not_active Expired - Lifetime
- 2004-07-19 DE DE602004009197T patent/DE602004009197D1/de not_active Expired - Lifetime
- 2004-07-19 WO PCT/IN2004/000216 patent/WO2005009419A2/en not_active Ceased
-
2007
- 2007-04-26 US US11/789,974 patent/US20070203248A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1653948B1 (de) | 2007-09-26 |
| DE602004009197D1 (de) | 2007-11-08 |
| WO2005009419A2 (en) | 2005-02-03 |
| WO2005009419A3 (en) | 2005-03-24 |
| US20070203248A1 (en) | 2007-08-30 |
| EP1653948A2 (de) | 2006-05-10 |
| US20050020666A1 (en) | 2005-01-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |